SPDR Dow Jones Industrial Average ETF

SPDR S&P 500 ETF Trust

Invesco QQQ Trust Series 1

GameStop Corp. engages in offering games and entertainment products through its ecommerce properties and stores. The firm’s stores and ecommerce sites operate primarily under the names GameStop, EB Games, and Micromania. It operates through the following geographical segments: United States, Canada, Australia, and Europe. The company was founded by Daniel A. DeMatteo in 1996 and is headquartered in Grapevine, TX.

Gamestop Corporation - Ordinary Shares - Class A

GameStop Corp

GameStop is trending following an unsolicited bid to acquire eBay in a multi-billion dollar cash-and-stock deal, sparking intense community debate over potential share dilution versus the strategic vision of transforming into a broader e-commerce platform. Investors are expressing skepticism regarding financing and the viability of the deal, while many community members remain focused on the potential for a massive short squeeze driven by retail momentum.

SoundHound AI, Inc. engages in the development, owning, and commercialization of voice, sound, and natural language artificial intelligence technologies and related activities. The company was founded on September 2, 2005 and is headquartered in Santa Clara, CA.

SoundHound AI Inc - Ordinary Shares - Class A

SoundHound AI Inc

SoundHound AI is currently surging due to a combination of heavy short interest and positive momentum, leading investors to speculate on an impending short squeeze ahead of upcoming earnings. The community is focused on high borrow rates and limited share availability, fueling bullish sentiment despite broader market volatility.

Xanadu Quantum Technologies Ltd. engages in the provision of quantum computing solutions for enterprise and government customers. The company was founded by Christian Weedbrook on October 2, 2025 and is headquartered in Toronto, Canada.

Xanadu Quantum Technologies Ltd. - Ordinary Shares - Class B (Sub Voting)

Xanadu Quantum Technologies is experiencing extreme volatility and intense community debate following a share resale registration that investors are interpreting as either a massive dilution event or a standard unlock of existing shares. While some traders are aggressively buying the dip, banking on the company's photonic technology and potential government contracts, others are labeling the recent price action as a classic pump-and-dump scheme and warning of significant downward pressure.

Micron Technology, Inc. engages in the provision of innovative memory and storage solutions. It operates through the following segments: Compute and Networking Business Unit (CNBU), Mobile Business Unit (MBU), Embedded Business Unit (EBU), and Storage Business Unit (SBU). The CNBU segment includes memory products and solutions sold into client, cloud server, enterprise, graphics, and networking markets. The MBU segment is involved in memory and storage products sold into smartphone and other mobile-device markets. The EBU segment focuses on memory and storage products sold into automotive, industrial, and consumer Markets. The SBU segment consists of SSDs and component-level solutions sold into enterprise and cloud, client, and consumer storage markets. The company was founded by Ward D. Parkinson, Joseph Leon Parkinson, Dennis Wilson, and Doug Pitman on October 5, 1978 and is headquartered in Boise, ID.

Micron Technology Inc.

Micron Technology Inc

Micron Technology is trending as a key beneficiary of the ongoing AI infrastructure build-out, with the community actively debating whether the company has transitioned from a cyclical memory player to a structural AI hardware leader. Investors are closely monitoring high-conviction analyst price targets and significant demand for HBM that has caused supply shortages, leading to widespread discussion about the sustainability of the stock's parabolic climb.

Skycorp Solar Group Ltd. is a holding company which designs, develops, manufactures and sells solar PV products and solar power system solutions services, through its indirectly wholly owned subsidiary. Its products include One-stop Solar system, Inverter, LFP Battery, Balcony Storage, and PV Cable. It operates through the following segments: Solar PV Products, High Performance Computing Products, and Others. The Solar PV Products segment includes servers, photovoltaic cable, and photovoltaic connectors. The High Performance Computing Products segment refers to the HPC servers and accessories delivered to the customers. The company was founded on January 19, 2022 and is headquartered in Ningbo, China.

Skycorp Solar Group Ltd. - Ordinary Shares - Class A

Skycorp Solar Group Ltd.

Skycorp Solar Group is trending following news of a significant acquisition of a majority stake in Nanjing Cesun Power and a private placement, fueling community speculation about a potential short squeeze. Traders are actively debating the impact of the limited float and lock-up periods on price volatility, with many monitoring for explosive momentum.

CNS Pharmaceuticals, Inc. is a preclinical stage pharmaceutical company, which engages in the development of anticancer drug candidates for the treatment of primary and metastatic brain and central nervous system tumors. Its product pipeline includes berubicin, and CNS-12. The company was founded by Waldemar Priebe in July 2017 and is headquartered in Houston, TX.

Cns Pharmaceuticals Inc

CNS Pharmaceuticals is experiencing significant market interest driven by an oversubscribed private placement that investors are interpreting as validation for its new strategic focus on neurology and oncology. The community is actively debating the stock's extreme volatility and low float, with many participants focused on potential short-squeeze dynamics and the impact of the company's shift toward acquiring clinical-stage assets.

Clene, Inc. is a clinical-stage biopharmaceutical company, which focuses on the discovery, development, and commercialization of novel clean-surfaced nanotechnology therapeutics. It offers a nanotechnology drug platform for the development of a new class of orally administered neurotherapeutic drugs. The company was founded in 2013 and is headquartered in Salt Lake City, UT.

Clene Inc

Clene Inc. is currently trending as investors anticipate the upcoming release of clinical data concerning the company's ALS drug candidate, CNM-Au8, following an FDA-guided development program. Community discussion is heavily focused on the potential for an accelerated approval NDA filing, with traders analyzing insider activity and volume patterns as they wait for definitive regulatory updates.

eBay, Inc. is a commerce company, whose platforms include an online marketplace and its localized counterparts, including off-platform businesses in South Korea, Japan, and Turkey, as well as eBay’s suite of mobile apps. It offers a platform for various product categories, including parts and accessories, collectibles, fashion, electronics, and home & garden. eBay generates revenue mainly through fees from sales, payment processing, and advertising. The company was founded by Pierre Morad Omidyar in September 1995 and is headquartered in San Jose, CA.

EBay Inc.

eBay Inc

eBay is trending following the announcement of an unsolicited, non-binding acquisition bid from GameStop, sparking intense debate among retail traders regarding the feasibility of such a large-scale merger. While some market participants see potential for a major e-commerce turnaround, others remain skeptical, focusing on the significant funding gap and the potential for shareholder dilution.

Alpha Tau Medical Ltd. is a clinical-stage oncology therapeutics company, which focuses on the research, development, and commercialization of diffusing alpha-emitters radiation therapy for the treatment of cancer. The firm is involved in the clinical trials at cancer centers with indications that include skin cancer, oral cavity cancer, breast cancer, and pancreatic cancer. The company was founded by Uzi Sofer, Yona Keisari, and Itzhak Kelson in November 2015 and is headquartered in Jerusalem, Israel.

Alpha Tau Medical Ltd

ALPHA TAU MEDICAL LTD

Alpha Tau Medical is trending as investors react to a significant expansion of its pancreatic cancer trials in both the U.S. and Europe, alongside anticipation for upcoming data presentations at Digestive Disease Week. Community sentiment is overwhelmingly bullish, with active discussions focused on the company's clinical progress, potential for rapid scaling, and the high-conviction belief that current market valuations do not fully reflect the platform's efficacy.

Federal National Mortgage Association is a government-sponsored company, which engages in the provision of liquidity for purchases of homes and financing of multifamily rental housing and refinancing existing mortgages. It operates through the Single-Family and Multifamily segments. The Single-Family segment offers liquidity to the mortgage market and increases the availability and affordability of housing for single families. The Multifamily segment includes guaranty fees on mortgages and on multifamily mortgage loans. The company was founded in 1938 and is headquartered in Washington, DC.

Federal National Mortgage Association

Fannie Mae shares are rallying as the community reacts to high-profile bullish sentiment from prominent investors, fueling intense speculation about a potential end to conservatorship. Investors are actively discussing the possibility of a major policy catalyst and a subsequent IPO, leading to significant trading volume and a sentiment shift focused on the stock's long-term valuation potential.

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Bitcoin

Ethereum

Solana

Ripple

Dogecoin

Cardano

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Nifty 50

Nifty Bank

Reliance Industries Ltd.

Zomato Ltd.

Tata Consultancy Services

Tata Motors Ltd.

HDFC Bank Ltd.

ITC Ltd.

Adani Enterprises Ltd

Axis Bank Ltd

Bajaj Finance Ltd

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SPDR S&P 500 ETF

Apple Inc.

Tesla Inc

Microsoft Corporation

NVIDIA Corp

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<ul class="summary-bullets"><li>Investor focus shifted toward a shareholder vote on a proposal to expand the company’s incentive share pool by 20 million shares.</li><li>CEO Angelos Stergiou urged investors to support the expansion, reiterating confidence in the Phase 3 Regal trial.</li><li>The Regal study had recorded 72 overall-survival events as of Dec. 26, nearing the 80-event threshold required to trigger topline analysis.</li></ul>Shares of Sellas Life Sciences Group, Inc. (SLS) hovered near the $5 level on Thursday as investor attention shifted from upcoming AML trial results to a shareholder vote on a proposal to add 20 million shares to the company’s incentive plan.SLS stock jumped 6% on Thursday to end at 4.95, climbing close to the $5 threshold last hit more than a month ago.&nbsp;<h2 class="st-heading-2">Sellas Seeks 20M Share Incentive Expansion</h2>Sellas CEO Angelos Stergiou recently urged shareholders to support a proposal to expand the share reserve under the company’s 2023 Amended and Restated Equity Incentive Plan by 20 million shares, saying his conviction in the Phase 3 Regal study evaluating GPS in acute myeloid leukemia (AML) remains unchanged.Sellas previously disclosed that 72 overall-survival events had been recorded as of Dec. 26, moving the study closer to the 80-event threshold required for topline analysis. Stergiou also said that a slower accumulation of survival events in oncology trials can sometimes indicate that patients are living longer than initially expected.The proposed equity plan would replenish the company’s stock-based compensation pool after Sellas said only 7,991 shares remained available for future awards under the existing plan as of mid-April. Approval would also allow a previously approved grant of 1.1 million restricted stock units to Stergiou to take effect.As of April 15, Sellas reported 2.64 million stock options and 2.26 million restricted stock units outstanding, with total equity overhang representing about 2.6% of shares outstanding.<h2 class="st-heading-2">Retail Flags Dilution Concerns Near $5</h2>Retail investors on Stocktwits voiced concerns about the timing and scale of the proposed equity plan, particularly as the Regal Phase 3 milestone approaches. Sentiment for SLS slipped to ‘neutral’ from ‘bullish’ levels a week ago amid a 32% rise in 24-hour message volumes.&nbsp;<figure class="image"><img src="https://news.stocktwits-cdn.com/sls_ss_png_a286a7daf7.webp" alt="sls ss.png" width="966" height="146"><figcaption>SLS sentiment and message volume as of May 1 | Source: Stocktwits</figcaption></figure>Some investors&nbsp;<a href="https://stocktwits.com/nashvilleRN/message/651903417">argued</a> that the proposal represented about a 20% dilution, questioning whether such a request should be made before the full Phase 3 data are revealed. Meanwhile, another turned&nbsp;<a href="https://stocktwits.com/Usser888990/message/651903766">bearish</a> at the idea of diluting the stock around the $5 range.&nbsp;In a separate&nbsp;<a href="https://stocktwits.com/FlockOfSeagulls/message/651841400">investor poll</a>, about 70% of respondents indicated they planned to vote against the proposal, compared with 30% supporting it. Another investor&nbsp;<a href="https://stocktwits.com/Bio_Wizard/message/651898473">said</a> that they had already voted against the measure and rotated capital into long-term equities.&nbsp;<h2 class="st-heading-2">AML Pipeline Remains In Focus</h2>Despite the debate regarding share dilution, investors are closely watching the upcoming milestones from the company’s AML programs. The event-driven Phase 3 Regal study is evaluating GPS, which activates immune cells that help destroy leukemia cells in patients whose AML returned but later entered remission after additional therapy.Stergiou also pointed to 2026 as an important year for the company’s CDK9 inhibitor SLS009, with clinical updates and top-line data expected from ongoing Phase 2 studies.Preclinical findings presented ahead of a recent cancer summit showed that the therapy triggered the natural self-destruction process in leukemia cells, reduced survival-support proteins, and remained active in AML linked to ASXL1 and TP53 mutations, which are typically associated with poorer outcomes.For updates and corrections, email newsroom[at]stocktwits[dot]com.Read Next:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/rivian-stock-amazon-drives-auto-revenue-r2-buzz/cZQNMpZReIN">Rivian Stock Slides Overnight: Investors Look Past R2 Buzz To Amazon’s Growing Grip On Auto Revenue&nbsp;</a>

SLS stock jumped 6% on Thursday to end at 4.95. (Photo credit: Getty Images)

SLS Stock Tests $5 Again: Retail Targets ‘No’ Vote On 20M Share Dilution Push Before AML Trial Results 

Sellas reported 2.64 million stock options and 2.26 million RSUs outstanding as of April 15, representing an equity overhang of about 2.6% of the total float.

Equity

<ul class="summary-bullets"><li>Markets eased from record highs as investors brace for the Fed rate decision and a crucial wave of Big Tech earnings.&nbsp;</li><li>Brent oil prices surged above $110 amid renewed geopolitical tensions in the Middle East.</li><li>Gold slips to a three-week low, signaling mixed safe-haven positioning.</li></ul>U.S. stock futures retreated from record highs early Tuesday as investors tread carefully ahead of big tech earnings and the Fed's rate decision tomorrow. Geopolitical tensions are also weighing on sentiment. Hopes for a swift resolution to the conflict in the Middle East dimmed after President Trump reportedly expressed skepticism over Iran’s latest peace proposal.Brent crude soared above $110, while gold slipped to a three-week low. As of 4:00 a.m. ET on Tuesday: Nasdaq futures declined 0.5%, S&amp;P 500 futures slipped 0.3%, Russell 2000 futures were down 0.1%, while Dow futures were flat.&nbsp;Retail sentiment toward the&nbsp;<a href="https://stocktwits.com/symbol/SPY">SPDR S&amp;P 500 ETF (SPY)</a>, an exchange-traded fund that tracks the S&amp;P 500 Index, has moved back to ‘bullish’ territory, while the&nbsp;<a href="https://stocktwits.com/symbol/QQQ">Invesco QQQ Trust (QQQ)</a> ETF, which tracks the Nasdaq-100 Index, has remained ‘bearish’, as the tech sector heads into a critical earnings stretch.&nbsp;Trending Stocks To WatchPoet Technologies (POET):&nbsp;Shares were down another 9% in early pre-market trade on news that&nbsp;Marvell Technologies (MRVL) canceled a purchase order connected to its Celestial AI unit.&nbsp;Sellas Lifesciences (SLS):&nbsp;A portfolio manager, Commonwealth Equity Services, known for backing several “Magnificent Seven” stocks, increased its stake in the cancer drugmaker ahead of a survival-event trigger in its Phase 3 acute myeloid leukemia (AML) program.Nvidia (NVDA) has solidified its status as the most valuable company in the world after hitting a new 52-week high on AI-driven momentum in Monday’s session.&nbsp;Google (GOOGL) has reportedly joined OpenAI and xAI in signing a deal with the U.S. Department of Defense to allow its AI models to be used for classified military work.&nbsp;Oracle (ORCL)&nbsp;is attracting retail interest, driven by buzz around OpenAI's financial health and Oracle’s role as its primary AI backbone.&nbsp;Bed Bath &amp; Beyond (BBBY)&nbsp;is trending on retail radar after reporting its first quarterly revenue growth in five years.&nbsp;Joby Aviation (JOBY):&nbsp;A successful air-taxi demo and a confirmed target for passenger flights in late 2026 are driving this stock 3% higher in early premarket trading.&nbsp;Dynatrace (DT):&nbsp;Activist investor Starboard Value has reportedly built a significant stake in the AI software maker.&nbsp;Intellia Therapeutics (NTLA) and Rocket Labs (RKLB): Cathie Wood’s ARK Invest sold off a portion of its position in Rocket Labs, while adding on to Intellia Therapeutics.&nbsp;Other tickers trending on Stocktwits&nbsp;at the time of writing included Moolec Science SA (MLEC), Canadian Solar Inc (CSIQ), Vir Biotechnology (VIR), and Nio Inc (NIO).Other Catalysts To WatchOn the economic front, traders will be watching the release of the JOLTS Job Openings and CB Consumer Confidence reports this morning.On earnings radar, watch out for quarterly reports from&nbsp;UPS (UPS), General Motors (GM), Commvault Systems (CVLT), JetBlue (JBLU), Sysco (SYY), Spotify (SPOT), Coca-Cola (KO), T-Mobile (TMUS), Kimberly Clark (KMB), Centene (CNC), and Zimmer Biomet (ZBH), before the bell. For updates and corrections, email newsroom[at]stocktwits[dot]com

Nasdaq, S&P 500 Futures Edge Lower Before Fed Call, Earnings Rush: Why POET, MRVL, NVDA, ORCL, SLS Are In Focus

Data from Stocktwits show mixed positioning, with retail turning bullish on SPY but remaining cautious on QQQ.

<ul class="summary-bullets"><li>Commonwealth Equity Services increased its stake by 32%, adding 9,226 shares worth $162,730.</li><li>CEO Angelos Stergiou reaffirmed confidence in the trial, saying his conviction in its commercial potential remains “as steadfast today as it was day 1.”</li><li>Sellas is also seeking shareholder approval to expand its equity incentive plan by 20 million shares.</li></ul>Shares of Sellas Life Sciences Group, Inc. (SLS) came into focus on early Tuesday after a portfolio manager, known for backing several “Magnificent Seven” stocks, increased its stake in the cancer drugmaker ahead of a survival-event trigger in its Phase 3 acute myeloid leukemia (AML) program.<a href="https://stocktwits.com/symbol/SLS">SLS stock</a> jumped over 9% on Monday amid rising hopes around the database-lock milestone for Sellas’ Regal study, which could unlock topline survival data from its lead immunotherapy candidate, GPS.<h2 class="st-heading-2">SLS Draws Fresh Institutional Interest</h2>On Monday, Commonwealth Equity Services increased its stake by 32%, adding 9,226 shares to bring its total holdings to 38,470 shares valued at about $162,730 as of March 31. The boost in stake places Sellas among its other heavyweight healthcare bets, including Eli Lilly, Pfizer, and UnitedHealth.Among its larger portfolio, Sellas sits among its “Magnificent Seven” allocations, including Apple, Nvidia, Microsoft and Amazon.Recently, BlackRock also disclosed ownership of 12.1 million shares, representing 6.8% of Sellas’ shares. Additionally, Dagco raised its position by 78% to 1.03 million shares valued at $4.35 million, making Sellas its second-largest allocation alongside healthcare holdings such as Merck, Thermo Fisher Scientific and Johnson &amp; Johnson.<h2 class="st-heading-2">CEO Reaffirms Confidence In Sellas’ AML Trial</h2>The increase in stake comes after Sellas CEO Angelos Stergiou said&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/sls-stock-jumps-overnight-ceo-backs-aml-drug-20m-share-plan/cZBNIW8Re2E">late Sunday</a> that his confidence in the Regal study’s commercial potential remains unchanged despite the trial remaining blinded. “My conviction in the REGAL trial’s prospects and ultimate commercial potential remains as steadfast today as it was day 1,” he said.The ongoing event-driven Phase 3 Regal study is evaluating GPS in patients whose acute myeloid leukemia returned but later entered remission following additional therapy. Final analysis is expected once 80 overall-survival events are recorded, which will trigger database lock, statistical analysis and unblinding. The company previously reported 72 survival events as of Dec. 26, bringing the study closer to the required threshold. Stergiou previously said that slower accumulation of survival events in oncology trials can sometimes indicate patients are living longer than initially expected.Beyond the Regal program, Stergiou also said investors should expect updates and topline data readouts from ongoing Phase 2 studies of the company’s CDK9 inhibitor SLS009 this year.&nbsp;<h2 class="st-heading-2">Sellas Proposes 20M Share Reserve Increase&nbsp;</h2>Alongside pipeline progress, Sellas is seeking shareholder approval to expand its share reserve under its 2023 Amended and Restated Equity Incentive Plan by 20 million shares.The company said that only 7,991 shares are available for future awards under the existing plan as of mid-April. The approval would allow a previously approved grant of 1.1 million restricted stock units to Stergiou to take effect. If rejected, the award would automatically be canceled, and alternative compensation arrangements may be required.<h2 class="st-heading-2">How Do Retail Traders Feel About SLS?</h2>On Stocktwits, retail sentiment for SLS was ‘bullish’ amid ‘high’ message volume.<figure class="image"><img src="https://news.stocktwits-cdn.com/sls_ss_png_656e44509c.webp" alt="sls ss.png" width="968" height="147"><figcaption>SLS sentiment and message volume as of April 28 | Source: Stocktwits</figcaption></figure>One user&nbsp;<a href="https://stocktwits.com/OnTheBalance/message/651586857">said</a>, “Far more important than Blackrock or Vanguard is the fact that private wealth and family offices have been actively buying and hoarding shares. Lot of money in that segment. Careful but patient money.”<stembedurl>https://stocktwits.com/OnTheBalance/message/651586857</stembedurl>Another user&nbsp;<a href="https://stocktwits.com/Macme/message/651533145">said</a>, “The CEO must have already discussed this 20 million shares with huge partners. It wil pass. Retail is just making noise. The real players like blackrock will surely approve.”<stembedurl>https://stocktwits.com/Macme/message/651533145</stembedurl>SLS stock has surged nearly 250% over the past year.&nbsp;For updates and corrections, email newsroom[at]stocktwits[dot]com.Read Next:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/rivian-ceo-400m-pay-retail-bullish-ahead-of-earnings/cZB8nCTRe5L">Rivian CEO Got $400M While EV Maker Lost $3.6B Last Year — Retail Is Bullish Anyway As Q1 Earnings Near&nbsp;</a>

SLS stock has surged nearly 250% over the past year. (Photo credit: Getty Images)

SLS Stock Gains Momentum: NVDA, MSFT Investor Loads Up Ahead Of AML Trial Milestone Trigger 

Commonwealth holds Sellas alongside major healthcare names like Eli Lilly, Pfizer, and UnitedHealth.

SELLAS Life Sciences Group (NASDAQ:SLS) Shares Gap Up - Still a Buy?

SELLAS Life Sciences Group (NASDAQ:SLS) Shares Gap Up - Still a Buy...

<ul class="summary-bullets"><li>The CEO reaffirmed confidence in the Phase 3 Regal trial evaluating GPS in AML, despite the study remaining blinded.</li><li>Sellas expects clinical updates and Phase 2 readouts for its CDK9 inhibitor, SLS009, this year.</li><li>BlackRock disclosed a 6.8% stake in the cancer drugmaker on Friday.</li></ul>Shares of Sellas Life Sciences Group, Inc. (SLS) jumped over 7% overnight late Sunday after its CEO signaled “steadfast” confidence in the company’s lead acute myeloid leukemia (AML) therapy and urged investors to support a proposal to expand its equity incentive plan by 20 million shares.<a href="https://stocktwits.com/symbol/SLS">SLS stock</a> slid about 15% last week, logging its worst weekly performance in nearly four months.<h2 class="st-heading-2">Sellas CEO Signals ‘Steadfast’ Confidence In Regal Trial</h2>CEO Angelos Stergiou said in a&nbsp;<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.linkedin.com/feed/update/urn:li:activity:7454295346865729537/">LinkedIn post</a> late Sunday that his conviction in the Regal trial’s commercial prospects remains unchanged despite the study still being blinded.“My conviction in the REGAL trial’s prospects and ultimate commercial potential remains as steadfast today as it was day 1,” he said. The ongoing event-driven Phase 3 Regal study is evaluating GPS in patients whose AML returned but later entered remission after additional therapy. Final analysis of the trial is expected once 80 overall-survival events are recorded, which triggers database lock, statistical analysis and unblinding.Sellas previously said 72 survival events had been recorded as of Dec. 26, bringing the study closer to the milestone required for topline analysis. Stergiou also said that slower accumulation of survival events in cancer studies can sometimes indicate that patients are living longer than initially expected.“While strict trial blinding prevents any definitive guarantees before unblinding, my belief in the asset—and the prolonged survival trend we are observing—has not diminished in the slightest,” Stergious said in the post.GPS targets Wilms Tumor-1 (WT1), a protein commonly found in many cancers and ranked by the National Cancer Institute as a leading immunotherapy target. The treatment uses engineered fragments of WT1 to activate key immune cells that help destroy cancer cells.<h2 class="st-heading-2">SLS009 Updates Expected This Year</h2>Stergiou also pointed to 2026 as an important year for&nbsp;the development of the CDK9 inhibitor SLS009. “Investors should look for clinical updates and top-line data readouts from our ongoing Phase 2 studies this calendar year,” he said.Recent lab findings presented ahead of a key cancer summit showed that the therapy helped trigger the natural self-destruction process in leukemia cells while reducing proteins that cancer cells rely on to survive. The drug also remained active in hard-to-treat forms of AML linked to ASXL1 and TP53 mutations, which are typically associated with poorer outcomes.Investor expectations had been building around potential updates from SLS009 last week, leaving the stock in&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/sls-stock-slips-after-hours-cancer-pipeline-silence-china-licensing-arbitration/cZBBanERI6u">wait-and-watch mode</a> after the anticipated pipeline developments did not immediately land at a cancer summit.<h2 class="st-heading-2">Sellas Seeks Approval To Add 20M Shares</h2>Alongside pipeline updates, Stergiou sought approval to expand the share reserve under its 2023 Amended and Restated Equity Incentive Plan by 20 million shares. The amendment would add more shares to the company’s stock-based compensation pool after Sellas disclosed that only 7,991 shares remained available for future awards under its existing plan as of mid-April.Approval of the new proposal would allow a previously approved grant of 1.1 million restricted stock units to Stergiou to take effect, while rejection would automatically cancel the award and could require the company to consider alternative compensation arrangements.As of April 15, Sellas reported 2.64 million stock options and 2.26 million restricted stock units outstanding, with total equity overhang representing about 2.6% of shares outstanding.&nbsp;<h2 class="st-heading-2">Institutional Participation Builds Ahead Of Catalysts</h2>Institutional participation in the stock has remained active ahead of expected clinical milestones. On Friday, BlackRock disclosed a stake of about 12.1 million shares, representing 6.8% of Sellas’ outstanding common stock.Data compiled by Quiver Quantitative showed last week that Dagco&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/sls-stock-premarket-dagco-raises-stake-ahead-of-aacr-leukemia-data/cZBIfhbRICL">increased its stake</a> by 78%, bringing its total holdings to 1.03 million shares valued at about $4.35 million as of March 31. The position now represents Dagco’s second-largest disclosed allocation at 1.01% of its portfolio, placing Sellas among its healthcare bets alongside larger pharma companies such as Merck, Thermo Fisher Scientific, and Johnson &amp; Johnson.<h2 class="st-heading-2">How Do Retail Traders Feel About SLS?</h2>On Stocktwits, retail sentiment for SLS has jumped to ‘bullish’ from ‘bearish’ levels over the past week amid ‘high’ message volume.<figure class="image"><img src="https://news.stocktwits-cdn.com/sls_ss_png_9245b89031.webp" alt="sls ss.png" width="973" height="142"><figcaption>SLS sentiment and message volume as of April 26 | Source: Stocktwits</figcaption></figure>One user&nbsp;<a href="https://stocktwits.com/vlucky16/message/651465697">said</a>, “Sterge doing what's best for patients and stockholders. Just sit back and watch warrants and loose shares get gobbled up. At some point Game Over for shorts!!!”<stembedurl>https://stocktwits.com/vlucky16/message/651465697</stembedurl>Another user&nbsp;<a href="https://stocktwits.com/PejalPapa/message/651464553">said</a>, “I would at least like to see an IDMC report with event no and a signal to keep going. Not sure how his posts like that are building a shareholder value with so much uncertainty on the direction of the trial.”<stembedurl>https://stocktwits.com/PejalPapa/message/651464553</stembedurl>SLS stock has surged 233% over the past year.&nbsp;For updates and corrections, email newsroom[at]stocktwits[dot]com.Read Next:&nbsp;<a href="https://stocktwits.com/news-articles/markets/cryptocurrency/jpmorgan-sees-tokenized-etfs-as-the-next-big-thing/cZBkpZpRe23">JPMorgan Sees Tokenized ETFs As The Next Big Thing, But Adoption Timeline Is Still Unclear</a>

SLS stock has surged 233% over the past year. (Photo credit: Getty Images)

SLS Stock Jumps Overnight: CEO Doubles Down On ‘Steadfast’ Confidence In AML Drug And Pushes For 20M Share Plan Approval 

Sellas is seeking approval to add 20 million shares to its equity plan after nearly exhausting its current pool, with only 7,991 shares remaining.

SELLAS Life Sciences Group (NASDAQ:SLS)  Shares Down 8.1%   - Here's Why

SELLAS Life Sciences Group (NASDAQ:SLS) Shares Down 8.1% - Here's Why...

<ul class="summary-bullets"><li>Anticipated updates on the company’s leukemia drug SLS009 did not land, dampening near-term catalyst momentum.</li><li>Earlier studies showed SLS009 triggered leukemia cell death and remained active in difficult-to-treat AML cases with ASXL1 and TP53 mutations.</li><li>Attention also remains on the Phase 3 Regal trial, where survival events are approaching the threshold required to begin topline analysis.</li></ul>Shares of Sellas Life Sciences Group, Inc. (SLS) slipped nearly 1% in after-hours trading on Tuesday as investors remained in wait-and-watch mode after expected cancer-pipeline updates failed to land, turning focus toward a pending China licensing arbitration decision tied to Phase 3 milestone payments for its lead acute myeloid leukemia (AML) program.<a href="https://stocktwits.com/symbol/SLS">SLS stock</a> ended the regular session about 1% higher at $5.03.<h2 class="st-heading-2">SLS009 Update Fails To Land</h2>Investor expectations had been building around potential updates on the company’s leukemia drug SLS009, which earlier studies showed could help trigger cancer cell death while blocking survival signals that leukemia cells rely on. The treatment also showed activity in hard-to-treat AML cases with ASXL1 and TP53 mutations, genetic changes often linked to poorer outcomes.SLS shares also drew investor attention on Tuesday after U.S. investment manager Dagco&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/sls-stock-premarket-dagco-raises-stake-ahead-of-aacr-leukemia-data/cZBIfhbRICL">increased</a> its stake in the company by 78% ahead of anticipated catalysts in the company's leukemia pipeline.<h2 class="st-heading-2">China Milestone Payment Dispute In Focus</h2>Focus has now turned to an arbitration proceeding involving Sellas and its Chinese partner 3D Medicines covering development and commercialization rights for 3D189, the regional version of the company’s immunotherapy candidate Galinpepimut-S (GPS), as well as 3D059, the regional version of SLS009.The arbitration includes disputes over milestone payments tied to the initiation of Phase 3 clinical development for 3D189, and whether the regional partner maintained sufficient expertise and resources to meet its obligations under the licensing agreement.The tribunal directed both parties to submit final closing submissions by April 21, moving the case into its decision phase.&nbsp;Sellas previously said that it received $10.5 million in upfront and milestone payments under its Greater China agreement with 3D Medicines, while up to $191.5 million in additional development, regulatory and commercial milestone payments remain possible under the licensing deal, excluding potential future royalties.<h2 class="st-heading-2">Regal Trial Readout Watch Builds</h2>Beyond the arbitration process, investor attention continues to center on the company’s ongoing Phase 3 Regal trial evaluating GPS as a maintenance therapy for AML patients whose disease returned but later entered remission after additional therapy.Sellas previously said 72 overall survival events had been recorded as of late December, approaching the 80-event threshold required to begin topline analysis. CEO Angelos Stergiou has said that slower accumulation of survival events in oncology trials can sometimes indicate patients are living longer than expected compared with historical assumptions.However, with no meaningful update emerging from the summit session as expected, attention appears to shift toward another near-term catalyst for the drugmaker.&nbsp;<h2 class="st-heading-2">How Do Retail Traders Feel About SLS?</h2>On Stocktwits, retail sentiment for SLS has improved to ‘bullish’ from ‘neutral’ levels a day ago amid ‘high’ message volumes.<figure class="image"><img src="https://news.stocktwits-cdn.com/sls_ss_png_8e6702e3ff.webp" alt="sls ss.png" width="968" height="144"><figcaption>SLS sentiment and message volume as of April 21 | Source: Stocktwits</figcaption></figure>One user&nbsp;<a href="https://stocktwits.com/Arnold_Stonkinator/message/650962118">noted</a> that while the SLS009 poster presentation drew attention, the absence of a formal company update or management communication on National AML Awareness Day stood out.<stembedurl>https://stocktwits.com/Arnold_Stonkinator/message/650962118</stembedurl>Another user expressed frustration, saying, “If they are going to go silent then do that and don't go to conferences, don't tweet, stop communicating completely.&nbsp; It just gives Shorts something else to see. Sterg we don't want to hear from you unless it is a BO.”<stembedurl>https://stocktwits.com/StandingByWaiting/message/650959906</stembedurl>SLS stock has surged 290% over the past year.&nbsp;For updates and corrections, email newsroom[at]stocktwits[dot]com.Read Next:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/hims-stock-pares-losses-after-hours-citi-amazon-glp1-caveat/cZBB74RRI6q">HIMS Stock Pares Losses After-Hours: Citi Flags ‘Big Caveat’ In Amazon’s GLP-1 Push That Limits Risk To Hims Model</a>

SLS stock has surged 290% over the past year.  (Photo credit: Getty Images)

SLS Stock Slips After-Hours As Cancer Pipeline Silence Frustrates Retail — China Licensing Fight Now In Spotlight

SLS Stock - Investor focus has shifted to an ongoing arbitration with 3D Medicines over Phase 3 milestone payments tied to the Greater China rights for GPS and SLS009.

Investor focus has shifted to an ongoing arbitration with 3D Medicines over Phase 3 milestone payments tied to the Greater China rights for GPS and SLS009.

<ul class="summary-bullets"><li>Dagco added 451,240 shares, making Sellas its second-largest holding at 1.01% of portfolio weight.</li><li>The stake increase comes ahead of AACR presentation of preclinical data on SLS009, Sellas’ CDK9 inhibitor targeting acute myeloid leukemia (AML).</li><li>Investor focus remains centered on the Phase 3 Regal trial of GPS, with 72 of 80 required survival events recorded as of Dec. 26, moving the study closer to topline analysis.</li></ul>Shares of Sellas Life Sciences Group, Inc. (SLS) jumped 5% in premarket trading on Monday after U.S. investment manager Dagco increased its stake by 78% ahead of a major AACR leukemia data catalyst and the closely watched Regal survival trigger.<a href="https://stocktwits.com/symbol/SLS">SLS stock</a> snapped four sessions of gains on Monday to end over 4% lower at $4.99.<h2 class="st-heading-2">Dagco Loads Up Ahead Of SLS009 AACR Data</h2>Data compiled by Quiver Quantitative showed that Dagco added 451,240 shares on Tuesday, bringing its total holdings to 1.03 million shares valued at $4.35 million as of March 31. The position now represents its second biggest holding at 1.01% of Dagco’s disclosed portfolio, placing Sellas among its healthcare bets alongside larger pharma holdings such as Merck, Thermo Fisher Scientific and Johnson &amp; Johnson.The stake increase comes just as Sellas prepares to present new preclinical findings on SLS009, its CDK9 inhibitor for acute myeloid leukemia (AML), during a poster session at AACR in San Diego on Tuesday.According to the company, lab studies showed that SLS009 triggered leukemia-cell death by increasing activity of caspase-3, a protein involved in the body’s natural cell-death process, while lowering survival signals such as MCL-1 and survivin that help cancer cells persist. The drug also showed stronger potency with repeated exposure, with early biological effects appearing within hours and becoming more pronounced over 24 hours.Notably, SLS009 remained active in AML carrying ASXL1 and TP53 mutations, which are genetic subtypes associated with treatment resistance and poorer outcomes.&nbsp;<h2 class="st-heading-2">Regal Survival Countdown In Focus</h2>While the AACR presentation represents a near-term catalyst, investor attention remains firmly centered on the company’s ongoing Phase 3 Regal trial evaluating GPS, an immunotherapy targeting the Wilms Tumor-1 antigen, as a maintenance treatment for AML patients whose disease returned but later entered remission after additional therapy.The event-driven study will begin final analysis once 80 overall-survival events are recorded. Sellas previously said 72 events had been logged as of Dec. 26, bringing the trial closer to the threshold required to initiate topline analysis.CEO Angelos Stergiou previously said that slower accumulation of survival events in oncology trials can sometimes indicate patients are living longer than expected compared with historical assumptions. Once the 80th event occurs, the company plans to proceed with database lock, statistical analysis, trial unblinding and disclosure of topline results.<h2 class="st-heading-2">How Do Retail Traders Feel About SLS?</h2>On Stocktwits, retail sentiment for SLS was ‘extremely bullish’ amid ‘extremely high’ message volume.<figure class="image"><img src="https://news.stocktwits-cdn.com/sls_ss_png_226ba9d4c9.webp" alt="sls ss.png" width="973" height="147"><figcaption>SLS sentiment and message volume as of April 21 | Source: Stocktwits</figcaption></figure>One user&nbsp;<a href="https://stocktwits.com/yG19/message/650823713">noted</a> Diagco’s stake and said, “It's likely clearly see the asymmetric upside with the margin of safety of no REGAL downside.”<stembedurl>https://stocktwits.com/yG19/message/650823713</stembedurl>Another user&nbsp;<a href="https://stocktwits.com/vlucky16/message/650846855">said</a>, “Can't wait to get update on 009, since GPS has been put on hold for an 80th event that might happen from old age.”<stembedurl>https://stocktwits.com/vlucky16/message/650846855</stembedurl>SLS stock has surged over 280% over the past year.&nbsp;For updates and corrections, email newsroom[at]stocktwits[dot]com.Read Next:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/tesla-stock-premarket-ross-gerber-brand-backlash-ai-pivot-earnings-check/cZBIOqKRICO">Tesla Stock Rises Premarket: Investor Ross Gerber Says ‘People Just Hate The Brand Now’ As AI Pivot Faces Earnings Reality Check</a>

SLS Stock Jumps Premarket: US Investor Dagco Boosts Stake By 78% Ahead Of Fresh Cancer Drug Data Reveal 

Sellas is now Dagco’s second-largest disclosed holding, putting the small-cap leukemia biotech alongside pharma giants like Merck and Johnson & Johnson.

Wall Street Analysts Think SELLAS Life Sciences Group, Inc. (SLS) Could Surge 66.09%: Read This Before Placing a Bet

The mean of analysts' price targets for SELLAS Life Sciences Group, Inc. (SLS) points to a 66.1% upside in the stock. While this highly sought-after metric has not proven reasonably effective, strong agreement among analysts in raising earnings estimates does indicate an upside in the stock.

While SLS stock has surged nearly 300% over the past year, ATNM has climbed 7% over the same period. (Photo credit: Getty Images)

SLS Vs ATNM: Which Cancer Stock Has Bigger Upside Ahead Of Fresh Data Reveal?

Analyst estimates suggest ATNM carries the wider valuation runway, with 342% upside versus about 66% for SLS.

SELLAS Life Sciences Group, Inc. is a clinical stage biopharmaceutical company, which engages in the development and commercialization of immunotherapeutic for cancer indications. Its product pipeline includes galinpepimut-S. The company was founded by Angelos M. Stergiou on April 3, 2006 and is headquartered in New York, NY.

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Sophisticated analysis of patient survival statistics and trial duration, arguing that current data points to a high probability of success for GPS.

Active speculation regarding a major buyout deal, with frequent comparisons to Lilly and potential multi-billion dollar acquisition values.

High-intensity clash between long-term investors tracking fundamental milestones and skeptical traders labeling the price action and management as a scheme.

Discussion centered on FDA designations like Fast Track and RTOR, and how these catalysts could accelerate approval timelines for clinical success.

Polarizing debate among shareholders concerning upcoming RSU proposals, share offerings, and corporate transparency issues regarding compensation.

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