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Altimmune, Inc. is a clinical stage biopharmaceutical company, which focuses on the development of novel peptide-based therapeutics for the treatment of obesity and liver diseases. The company's lead product candidate, pemvidutide, is a GLP-1/glucagon dual receptor agonist that is being developed for the treatment of obesity and NASH. In addition, Altimmune is developing HepTcell, an immunotherapeutic designed to achieve a functional cure for chronic hepatitis B. The company was founded in 1997 and is headquartered in Gaithersburg, MD.

Altimmune Inc

A recent $75 million direct offering to an undisclosed institutional investor, coupled with a notable increase in Vanguard's stake, has Altimmune driving vigorous community debate over whether this development validates its 'best-in-class' MASH drug for a strategic partnership or reflects a costly dilution to fund upcoming Phase 3 preparations.

Oxford Lane Capital Corp. is a closed-end management investment company, which engages in investing in debt and equity tranches of collateralized loan obligation vehicles. The company was founded on June 9, 2010 and is headquartered in Greenwich, CT.

Oxford Lane Capital Corp

Oxford Lane Capital Corp is trending after reporting significantly missed earnings, announcing a 50% dividend cut, and hitting a new 52-week low on heavy volume, fueling widespread community outrage over management and concerns about the CLO market's impact.

Luckin Coffee, Inc. engages in providing food and beverage items, and operates coffee retail stores. It has a pioneered a technology-driven retail network to provide coffee and other products of high quality, high convenience and high affordability to customers. The company manages pick-up stores, relax stores, and delivery kitchens. It also offers tea, snacks, and light meals through its mobile application. The company was founded by Zhi Ya Qian, Fei Yang and Jin Yi Guo on June 16, 2017 and is headquartered in Xiamen, China.

Luckin Coffee Inc - ADR

Luckin Coffee is trending as a key competitor ends its aggressive price war, fueling investor optimism for significantly improved profit margins, while the community debates whether this, alongside rapid store expansion, will finally unlock appreciation for the undervalued, OTC-listed stock.

Roblox Corp. engages in the provision of online gaming services. Its platform consists of Roblox Client, Roblox Studio, and Roblox Cloud. Roblox Client is an application that allows users to explore 3D digital worlds. Roblox Studio is the toolset that allows developers and creators to build, publish, and operate 3D experiences and other content accessed with Roblox Client. Roblox Cloud includes the services and infrastructure that power the human co-experience platforms. The company was founded by Erik Cassel and David B. Baszucki in March 2004 and is headquartered in San Mateo, CA.

Roblox Corporation - Ordinary Shares - Class A

Roblox Corp.

Roblox is trending due to a sharp decline fueled by market concerns over Google's new AI-powered 3D world creation tool and ongoing lawsuits regarding child safety on its platform. This has led to a split in community sentiment, with some viewing it as an "overreaction" and a "buy-the-dip" opportunity given strong user engagement and viral content, while others highlight profitability challenges and the potential impact of new age verification policies.

Memecoin on Cronos launched by the Cro Crow community

crow with knife

Crow with Knife ($CAW) is trending as a multi-chain meme coin, drawing buzz for its deflationary burn mechanism and an enthusiastic community that sees it as the "king of the memes" poised to generate significant activity across Solana, Cronos, and Base.

Fefe is a memecoin inspired by Matt Furie's book "Mindviscosity," published in 2020.  Follow FEFE, the alter ego of PEPE in the book “Mindviscosity” by Matt Furie.  Fefe is a main character in the book, who is a laid back and carefree frog living in a whimsical world. Fefe's relaxed and adventurous spirit captures the heart of this imaginative universe.  Launched stealth with no presale, zero taxes, LP burnt and contract renounced - TAX: 0/0 This narrative has its roots in a fascinating story.  Join us and become part of the $FEFE community today!

Fefe

Community discussion around FEFE is intensely bullish, driven by chart patterns indicating controlled accumulation and a potential breakout. Many are actively touting its strong narrative as the direct representation of $PEPE by its original creator, viewing it as a micro-cap with significant upside potential.

First Majestic Silver Corp. engages in the production, development, exploration and acquisition of mineral properties. It owns and operates producing mines in México including the La Encantada Silver Mine, La Parrilla Silver Mine, San Martin Silver Mine, La Guitarra Silver Mine, Del Toro Silver Mine, Santa Elena Silver & Gold Mine, and San Dimas Silver & Gold Mine. The company was founded by Keith Neumeyer on September 26, 1979 and is headquartered in Vancouver, Canada.

First Majestic Silver Corporation

First Majestic Silver Corporation is trending as silver prices continue to surge and command significant premiums in physical markets, with the community actively discussing potential market manipulation suppressing paper prices. Many investors view recent volatility and miner underperformance as a prime opportunity to acquire shares ahead of anticipated strong earnings, believing the broader silver bull market is poised for further expansion.

Pyth Network is a decentralised oracle network designed to provide real-time financial market data to decentralised applications (dApps) across multiple blockchains. It allows developer to secure smart contracts with reliable, low-latency market data from institutional sources, and build apps with high-fidelity oracle feeds designed for mission-critical systems.

Pyth Network

PYTH is trending due to its recent Robinhood listing and the community's focus on its new PYTH Reserve for token buybacks, alongside its expanding role as an oracle for institutional Real World Asset (RWA) price feeds.

Joby Aviation, Inc. is a transportation company, which engages in developing an all-electric, vertical take-off and landing aircraft that intends to operate as a commercial passenger aircraft. The company was founded by Bevirt Joebenn in 2009 and is headquartered in Santa Cruz, CA.

Joby Aviation Inc

Joby Aviation is trending due to a significant capital raise and stock offering, which has sparked mixed community reactions concerning share dilution versus providing essential funding to accelerate FAA certification, manufacturing scaling, and its anticipated 2026 commercial launch. Investors are actively debating the long-term growth potential against current pre-revenue challenges, with many viewing the dip as a strategic entry point given Joby's strong partnerships and lead in the eVTOL market.

Archer Aviation, Inc. engages in the development of electric vertical take-off and landing (eVTOL) aircraft. The company was founded by Brett Adcock and Adam Goldstein on October 16, 2018, and is headquartered in San Jose, CA.

Archer Aviation Inc - Ordinary Shares - Class A

Archer Aviation Inc

Archer Aviation is gaining attention following a new partnership with Serbia to introduce air taxi operations and BlackRock's significant stake, which fuels community discussions contrasting its strategic positioning and financial strength against competitors facing capital raises and dilution.

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Telomir Pharmaceuticals (NASDAQ:TELO) Shares Down 8.9% - Here's What Happened

Telomir Pharmaceuticals (NASDAQ:TELO) Shares Down 8.9% - Here's What Happened...

<ul><li>According to Telomir, more than 60,000 new cases of Leukemia are diagnosed each year in the U.S.</li><li>Leukemia cells rely heavily on iron as a fuel source, and Telomir-1 in previous research demonstrated the ability to reduce intracellular iron levels.&nbsp;</li><li>The new findings expand on the experimental drug’s previously reported activity in triple-negative breast, pancreatic, and aggressive prostate cancer models.</li></ul>Telomir Pharmaceuticals, Inc. (TELO) said on Friday that its investigational compound Telomir-1 killed aggressive human leukemia (HL60) cells in an in-vitro study.HL60 leukemia cells were treated with Telomir-1, which produced a clear, dose-dependent reduction in viable leukemia cells, indicating strong activity, the company said.Leukemia is a cancer of the blood and bone marrow defined by the uncontrolled growth of abnormal white blood cells.<a href="https://stocktwits.com/symbol/TELO">TELO shares</a> rose 8% at the time of writing.<h2 class="st-heading-2">New Findings</h2>According to Telomir, more than 60,000 new cases of Leukemia are diagnosed each year in the U.S. Leukemia cells rely heavily on iron as a fuel source, and Telomir-1 in previous research demonstrated the ability to reduce intracellular iron levels."The potency observed in HL60 leukemia cells is consistent with the broader biological patterns we have seen throughout Telomir's research…These findings support our scientific framework for evaluating Telomir-1 and inform the ongoing advancement of our overall oncology research program," the company’s chief scientific advisor, Itzchak Angel,<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://telomirpharma.com/#"> said</a>.The new findings expand on the experimental drug’s previously reported activity in triple-negative breast, pancreatic, and aggressive prostate cancer models. The compound is the company’s lead candidate.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>On Stocktwits, retail sentiment around TELO jumped from ‘bearish’ to ‘bullish’ territory over the past 24 hours, while message volume levels rose from ‘extremely low’ to ‘high’ levels.TELO stock is down 66% this year and by 69% over the past 12 months.Also See: <a href="https://stocktwits.com/news-articles/markets/equity/google-ai-infra-chief-must-double-ai-compute-twice-a-year/cLPMFWiREOK">Google AI Infra Chief Says It Must Double AI Compute Twice A Year To Meet Demand: Report</a>For updates and corrections, email newsroom[at]stocktwits[dot]com

In this photo illustration, the Telomir Pharmaceuticals logo is seen displayed on a smartphone screen. (Photo Illustration by Thomas Fuller/SOPA Images/LightRocket via Getty Images)

TELO Stock Jumps Pre-market After Early Study Results Show Leukemia Cell Death 

HL60 leukemia cells were treated with Telomir-1, which produced a clear, dose-dependent reduction in viable leukemia cells, indicating strong activity, the company said.

Equity

HL60 leukemia cells were treated with Telomir-1, which produced a clear, dose-dependent reduction in viable leukemia cells, indicating strong activity, the company said.


Shares of Telomir Pharmaceuticals surged nearly 40% in premarket trading on Thursday after the company announced promising new lab results showing that its experimental compound, Telomir-1, can selectively destroy triple-negative breast cancer cells.In laboratory studies using human triple-negative breast cancer (TNBC) cells, researchers observed that as Telomir-1 concentrations increased, more cancer cells stopped growing and eventually died. When iron was reintroduced into the system, the cells regained their ability to survive, pointing to a finding that confirmed Telomir-1’s effects are tied to iron regulation and cellular energy balance.The discovery is significant as TNBC cells are highly dependent on iron to fuel their rapid growth and spread. By cutting off that iron-driven metabolism, Telomir-1 appears to exploit a key vulnerability in these tumors, while normal cells, which process iron differently, remain largely unaffected.Telomir-1 has previously&nbsp;demonstrated the ability to reset abnormal DNA methylation patterns, which are chemical modifications that can alter gene function in preclinical models of cancer and age-related diseases.&nbsp;In this latest study, researchers believe its impact on energy and iron metabolism may stem from its influence on certain enzymes, known as Jumonji domain histone demethylases, which are known to drive tumor aggressiveness and treatment resistance.The study suggests that Telomir-1 may help restore the body’s natural balance, reactivating the normal genetic controls that cancer cells&nbsp;typically shut down to maintain growth.Telomir said it will now seek to use the drug in other hard-to-treat cancers, such as pancreatic and blood cancers, based on these results. The company also expects to soon begin animal studies, a crucial step in the process of seeking FDA approval to begin human trials.On Stocktwits, retail sentiment for Telomir was ‘extremely bullish’ amid ‘extremely high’ message volume.One user said they were surprised the stock hadn’t “gone nuclear” after the breast cancer news broke, adding that they expect it to “go parabolic” in the next session.<stembedurl>https://stocktwits.com/DadiscplinedTrader/message/631612120</stembedurl>Another user commented that the company could eventually attract a buyout offer from a larger pharmaceutical player, suggesting the stock might rise ten to fifteen times, comparing it to past biotech acquisition successes, including that of Provention Bio by Sanofi.<stembedurl>https://stocktwits.com/MarketAttack/message/631581755</stembedurl><a href="https://stocktwits.com/symbol/TELO">Telomir’s stock</a> has declined 60% so far in 2025.For updates and corrections, email newsroom[at]stocktwits[dot]com.

Telomir’s stock (TELO) has declined 60% so far in 2025. | Image source: Getty Images

Why Telomir Pharmaceuticals Stock Is Rising 40% Premarket Today

The company said that its experimental drug, Telomir-1, selectively kills aggressive triple-negative breast cancer cells by disrupting their iron-based energy systems.

Shares of Telomir Pharmaceuticals surged during after-hours trading Thursday following the announcement of early laboratory data from research conducted on progeria-affected cells from a young patient.The stock closed at $1.21 on Thursday, then surged 138.8% after hours to $2.89 following the preclinical data.The rare disease, Hutchinson-Gilford Progeria Syndrome (HGPS), emerges from one gene mutation which triggers the accumulation of progerin within the body. The disease affects fewer than 30 children in the U.S.Most start showing symptoms like growth delays and heart problems by age two, and many don’t live past their early teens.&nbsp;The only approved drug, Zokinvy, can add a few years to their lives but doesn’t stop the damage or undo what’s already happened.In the new study, conducted by Smart Assays using cells provided by the Progeria Research Foundation, Telomir-1 improved cell survival in a dose-dependent manner, even under stress conditions.&nbsp;It also reduced levels of reactive oxygen species, a marker of oxidative damage, and corrected iron-induced calcium overload linked to mitochondrial dysfunction.The company stated that these results, observed in actual patient-derived cells, demonstrate that Telomir-1 not only protects cells but also restores critical biological functions.&nbsp;Telomir-1 is designed to regulate metal ions, reduce oxidative stress, restore mitochondrial health, extend telomeres, reverse muscle loss, and reset age-related DNA methylation patterns.CEO Erez Aminov said that the findings support broader potential beyond progeria, including neurodegeneration and metabolic disorders.The results also validated prior preclinical work in animal models, where Telomir-1 extended lifespan and reversed age phenotypes in zebrafish and C. elegans models of Werner syndrome, an adult form of progeria.&nbsp;Telomir is completing IND-enabling studies and is due to meet with the U.S. Food and Drug Administration (FDA) to discuss potential regulatory pathways, including orphan drug designation.On Stocktwits, retail sentiment was ‘extremely bullish’ amid ‘extremely high’ message volume.The Telomir stream on Stocktwits saw a nearly 30% increase in watcher count over the past 24 hours, leading up to late Thursday, with the 24-hour message volume surging up by 8,600%.One user predicted a sharp move, saying Telomir could hit $8–$10 in post-market trading before “a crazy rocket” at the open toward $20 or higher.&nbsp;<stembedurl>https://stocktwits.com/time4themoon/message/621444979</stembedurl>Another user noted the stock’s momentum late in the session, and added that it was “seeing a nice bid going into the extended session close” with expectations to be “jamming in premarket.”<stembedurl>https://stocktwits.com/phijammaslamma/message/621430208</stembedurl><a href="https://stocktwits.com/symbol/TELO">Telomir’s stock</a> has declined 70.3% so far in 2025.For updates and corrections, email newsroom[at]stocktwits[dot]com.

Telomir Pharmaceuticals (TELO) said early lab results showed its drug candidate helped restore damaged cells from a child with progeria. (Photo credit: Getty Images)

Telomir Pharma Jumps In After-Hours Trading After Drug Reverses Damage In Progeria Cells; Retail Eyes Bigger Gains

The early lab study used cells from a child with progeria and showed improvements in cell survival, reduced oxidative stress, and restored mitochondrial function, which are key signs of aging. 

Telomir Pharma Jumps In After-Hours Trading After Drug Reverses Damage in Progeria Cells; Retail Eyes Bigger Gains

Telomir Pharmaceuticals, Inc. is a pre-clinical-stage pharmaceutical company, which focuses on the development and commercialization of TELOMIR-1, a novel small molecule being developed to function as an oral in situ therapeutic treatment for human stem cells. The firm’s initial focus on treatments to inhibit the production of pro-inflammatory cytokines, such as IL-17, by oral administration of TELOMIR-1 as a therapeutic treatment for stem cells in situ. TELOMIR-1 is under investigation to provide a potential therapeutic intervention against age-related inflammatory conditions such as hemochromatosis, as well as for post-chemotherapy recovery, by interrupting and preventing the IL-17 induced inflammatory pathways that create the systemic imbalance of cellular metals. The company was founded by Christopher C. Chapman Jr. on August 26, 2021 and is headquartered in Miami, FL.

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