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Hims & Hers Health, Inc. operates a telehealth consultation platform. It connects consumers to healthcare professionals, enabling them to access medical care for mental health, sexual health, dermatology and primary care. The company was founded in 2017 and is headquartered in San Francisco, CA.

Hims & Hers Health Inc - Ordinary Shares - Class A

Hims & Hers Health Inc

Hims & Hers Health is seeing a significant surge amid widespread rumors of an impending partnership with Novo Nordisk to sell obesity drugs on its platform, fueling intense short squeeze speculation due to high short interest and renewed optimism around its expanding peptide offerings.

United States Oil Fund LP - United States Oil Fund

United States Oil Fund

USO is seeing immense upward pressure as escalating geopolitical tensions in the Middle East have effectively disrupted shipping through the critical Strait of Hormuz, causing widespread concerns about global oil supply. The community is actively discussing the potential for significantly higher crude prices, viewing the situation as a genuine supply 'plumbing break' rather than just a fleeting fear-driven rally.

SELLAS Life Sciences Group, Inc. is a clinical stage biopharmaceutical company, which engages in the development and commercialization of immunotherapeutic for cancer indications. Its product pipeline includes galinpepimut-S. The company was founded by Angelos M. Stergiou on April 3, 2006 and is headquartered in New York, NY.

SELLAS Life Sciences Group Inc

Sellas Life Sciences (SLS) is gaining significant attention after its CEO highlighted potential "curative outcomes" for AML with GPS and SLS009, reinforcing expectations of extended patient survival in the REGAL trial and fueling widespread community speculation of an impending buyout and substantial short squeeze.

Brand Engagement Network, Inc. engages in the provision of conversational artificial intelligence assistants with the purpose of transforming engagement and analytics for businesses through security-focused, multimodal communication and human-like artificial intelligence assistants. The firm is also involved in delivering highly personalized, multi-modal artificial intelligence engagement with a focus on industries where there is a massive workforce gap and an opportunity to transform how consumers engage with networks, providers, and brands. The company is founded on March 14, 2024 and is headquartered in Jackson, WY.

Brand Engagement Network Inc

Brand Engagement Network (BNAI) is trending following news of an AI licensing partnership in Africa, sparking intense community discussion and predictions of a significant short squeeze driven by its notably low float and high cost to borrow.

uniQure NV engages in the discovery, development, and commercialization of innovative gene therapies. Its discoveries intend to treat hemophilia, Huntington's disease, glybera, and cardiovascular problems. The company was founded by Sander J. van Deventer in 1998 and is headquartered in Amsterdam, Netherlands.

uniQure N.V.

uniQure NV

uniQure (QURE) is trending as the community speculates that the impending departure of a key FDA official could lead to a more favorable regulatory path for its Huntington's disease gene therapy, AMT-130, after prior setbacks. This has sparked intense debate between those anticipating accelerated approval for gene therapies and bears who remain skeptical of the underlying drug data and the sustainability of the rally.

Capricor Therapeutics, Inc. is a clinical-stage biotechnology company, which focuses on the development of transformative cell and exosome-based therapeutics for treating Duchenne muscular dystrophy (“DMD”), a rare form of muscular dystrophy which results in muscle degeneration and premature death, and other diseases with unmet medical needs. Its product candidate consists of CAP-1002, Engineered Exosomes, CAP-2003, and Exosome-Based Vaccine. The company was founded on June 17, 1996 and is headquartered in San Diego, CA.

Capricor Therapeutics Inc

Community excitement for Capricor Therapeutics is surging, driven by news of a key FDA official's departure, with many believing this removes a significant hurdle for Deramiocel's approval for Duchenne Muscular Dystrophy and could trigger a substantial short squeeze ahead of upcoming Phase 3 data presentation.

Seeker is building a decentralized mobile ecosystem designed to challenge entrenched mobile incumbents through its TEEPin network architecture and community governance. It aims to solve the pain points of centralized app store gatekeeping, lack of developer freedom, and restricted user access to crypto applications. The vision is to create a community-owned platform with decentralized governance, no gatekeepers, direct developer-user access, and TEEPin security architecture.

Seeker

SKR (Seeker), a Solana Smartphone Token, is trending following recent exchange listings and an incentive offering a discount for purchases made with SKR. The community is keenly focused on breaching a key price resistance level amid high trading volume, with anticipation for future catalysts balanced by warnings of potential sell-offs from early participants.

What Is Pi Network? Pi Network is a social cryptocurrency, developer platform, and ecosystem designed for widespread accessibility and real-world utility. It enables users to mine and transact Pi using a mobile-friendly interface while supporting applications built within its blockchain ecosystem.  Supply Model and Mining Mechanism The Maximum Supply of Pi is 100 billion tokens. The Maximum Supply is comprised of the following: 65 Billion tokens (or 65%) are allocated for all community mining rewards; 10 billion (10%) are allocated for foundation reserves; 5 billion (5%) are allocated for liquidity purposes; and 20 billion (20%) are allocated for the Core Team. Each allocation mentioned above tracks the community Migrated Mining Rewards issuance pace, so the proportions of each allocation in the total supply remains the same at any given time.   The Effective Total Supply of Pi—the total Pi supply at the current time—allocates Pi proportionally the same as the Maximum Supply. Since every allocation tracks the Migrated Mining Rewards of the community, the Effective Total Supply can be calculated by dividing the current Migrated Mining Rewards of Pi on the Mainnet blockchain by 65%. The other allocations within the Effective Total Supply can then be calculated based on the same proportions as the Maximum Supply, e.g. at most 10% of the Effective Total Supply is available in the foundation reserve, 5% of the Effective Total Supply is available for liquidity purposes, and 20% of the Effective Total Supply is available for the Core Team. This remains true despite the fact that all tokens were minted at the genesis as technically required by the blockchain protocol.  Circulating Supply includes all Migrated Mining Rewards and all tokens that entered circulation from other buckets of the allocations, which at its maximum could be summed up to equal the Effective Total Supply.   Pi’s mining rewards are distributed based on an issuance formula that follows a declining exponential model defined in the Pi whitepaper. Users can increase the amount of mining rewards they receive based on their individual contributions to the network, like Security Circles, using utility-based Pi apps, running Nodes, etc. For each month, the amount of Pi to be distributed as mobile balance is capped and determined by the model, regardless of how many people or how many types of mining rewards there are during the month. The capping is achieved by the design of a system-wide base mining rate, and each type of mining rewards to each individual are just a multiplier of this base mining rate. As the monthly supplies always diminish, the base mining rate generally decreases over time.   Fewer Pi may also be issued because the real Pi issuance on the blockchain depends on Pioneers passing KYC and completing all steps required for migration to the Mainnet. Despite all efforts to facilitate and remind Pioneers to complete those required steps, there are always dropoffs along the way, resulting in less than all outstanding mobile balances to be issued on the blockchain. Because of this mechanism, the community issued amount (Migrated Mining Rewards) on the blockchain will likely be closer and closer to a line lower than the 65 billion. This is thus the reason for the variable Effective Total Supply which incorporates this effect. Effective Total Supply results from all Migrated Mining Rewards divided by 65%, as opposed to the Maximum Supply of 100 billion.  Ecosystem and Adoption Pi Network has built an integrated ecosystem that facilitates real-world transactions and decentralized applications. Pi can be used as a medium of exchange for goods and services, including online commerce and local brick-and-mortar businesses.  Users can engage with Core Team and community-built apps in the Pi ecosystem through the Pi Browser, where integrated features like the Pi Wallet provide a seamless experience. Events like PiFest 2024 showcased Pi’s growing adoption, with over 27,000 active sellers and 28,000 test merchants across 160 countries.  Who Are the Founders of Pi Network? Pi Network was founded by Dr. Nicolas Kokkalis and Dr. Chengdiao Fan, both of whom have PhDs from Stanford University and a passion for improving human lives through technology.  Dr. Nicolas Kokkalis is a Stanford PhD in EE and postdoc in CS with research on distributed systems and human-computer interaction. His work focuses on combining distributed systems and human computer interaction to bring cryptocurrency to everyday people. As a strong and long-term believer of the technical, financial and social potential of cryptocurrencies, he is determined to move them beyond their current limitations and is committed to bringing the power of blockchain to more people.  Dr. Chengdiao Fan holds a Stanford PhD in Anthropological Sciences, harnessing social computing to unlock human potential on a global scale. Chengdiao is building Pi Network to mobilize individuals all over the world to participate and be rewarded for their contributions, and establish an inclusive ecosystem for global citizens to unleash and capture their own agency, and in turn create utilities and productions for society and the world.  Compliance and Identity Verification Pi Network follows a one-account-per-person policy through its Know Your Customer (KYC) solution. This system combines machine automation and human verification to authenticate user identities while preserving privacy.  The KYC process emphasizes real individuals, combats fraudulent activities and enables fair participation in the mining process of the network. Pi’s identity verification approach balances scalability, security, and accessibility, allowing millions of users worldwide to validate their accounts while maintaining regulatory compliance.

Pi Network

Pi Network is trending as its community intensely debates the crypto's future, with many users expressing frustration over stalled KYC processes, unverified balances, and the lack of major exchange listings, while others remain steadfast in their long-term bullish outlook for the project.

Iovance Biotherapeutics, Inc. is a biopharmaceutical company, which engages in the development and commercialization of cell therapies as novel cancer immunotherapy products. Its lead product candidate, LN-144 for metastatic melanoma, is an autologous adoptive cell therapy utilizing tumor-infiltrating lymphocytes (TIL), which are T cells derived from patients' tumors. The company was founded by Robert T. Brooke on September 17, 2007 and is headquartered in San Carlos, CA.

Iovance Biotherapeutics Inc

Iovance Biotherapeutics is trending due to significant short covering and heightened M&A speculation in the oncology sector, particularly following the DAWN acquisition. The community is expressing strong optimism for its undervalued TIL therapy platform, anticipating key data readouts and a potential re-rating to fair value.

Direxion Shares ETF Trust - Direxion Daily Semiconductor Bull 3X Shares

Direxion Daily Semiconductor Bull 3X Shares

Direxion Daily Semiconductor Bull 3X Shares (SOXL) is seeing significant two-way action as investors react to ongoing geopolitical tensions impacting energy markets and mixed sentiment on AI demand post-earnings. While many are buying recent dips, confident in long-term chip sector growth, others remain wary of its struggle to break key resistance levels and the amplified volatility of this leveraged ETF.

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Tiziana Life Sciences (NASDAQ:TLSA) Trading Up 0.7% - Here's What Happened

Tiziana Life Sciences (NASDAQ:TLSA) Shares Up 0.7% - Should You Buy...

Tiziana Life Sciences (NASDAQ:TLSA) Stock Price Up 3.1% - Should You Buy?

Tiziana Life Sciences (NASDAQ:TLSA) Trading 3.1% Higher - Still a Buy...

Tiziana Life Sciences (NASDAQ:TLSA) Trading Up 7.4% - Still a Buy?

Tiziana Life Sciences (NASDAQ:TLSA) Shares Up 7.4% - What's Next...

Tiziana Life Sciences (NASDAQ:TLSA) Trading Down 4.4% - Here's Why

Tiziana Life Sciences (NASDAQ:TLSA) Shares Down 4.4% - Should You Sell...

Tiziana Life Sciences (NASDAQ:TLSA) Shares Down 4.5% - Here's Why

Tiziana Life Sciences (NASDAQ:TLSA) Trading Down 4.5% - Here's What Happened...

Nasdaq-listed shares of Tiziana Life Sciences (TLSA) rose 2% by Thursday afternoon after the company announced that it will advance its second asset, TZLS-501, and pursue non-dilutive funding strategies for its development.TZLS-501 is a fully human anti-IL-6 receptor monoclonal antibody or a biological therapy that blocks the action of interleukin-6 protein. Tiziana <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://ir.tizianalifesciences.com/news-releases/news-release-details/tiziana-advance-tzls-501-its-fully-human-il-6r-monoclonal">sees</a> potential to develop it as a monotherapy or in combination with its lead candidate, as well as with other anti-inflammatory and anti-infective agents.The company stated that TZLS-501 may offer therapeutic advantages in managing acute and chronic inflammatory conditions where excessive IL-6 signaling plays a central role, such as rheumatoid arthritis (RA), acute respiratory distress syndrome (ARDS), idiopathic pulmonary fibrosis (IPF), systemic lupus erythematosus, and various types of cancer.The company also stated that it will continue to advance intranasal Foralumab as its lead program, not diverting resources or focus from it. The firm is currently evaluating Foralumab in the treatment of multiple sclerosis, a chronic autoimmune disease in which the immune system attacks the protective myelin sheath surrounding nerve cells in the brain and spinal cord, causing numbness, vision problems, muscle weakness, balance issues, and fatigue.On Stocktwits, retail sentiment around <a href="https://stocktwits.com/symbol/TLSA">TLSA stock</a> jumped from ‘neutral’ to ‘bullish’ territory over the past 24 hours, while message volume rose from ‘normal’ to ‘high’ levels.<figure class="image"><img style="aspect-ratio:573/66;" src="https://news.stocktwits-cdn.com/Screenshot_2025_09_25_at_1_37_07_PM_png_487989b630.webp" alt="TLSA's Sentiment Meter and Message Volume as of 1:37 p.m. ET on Sept. 25, 2025 | Source: Stocktwits" width="573" height="66"><figcaption>TLSA's Sentiment Meter and Message Volume as of 1:37 p.m. ET on Sept. 25, 2025 | Source: Stocktwits</figcaption></figure>A Stocktwits user believes that the stock has “so much potential.”<stembedurl>https://stocktwits.com/GoCubsGo1124/message/629975723</stembedurl>Tiziana said on Thursday that the <a href="https://stocktwits.com/news-articles/markets/equity/tourmaline-stock-rockets-pre-market-after-novartis-buy-out-announcement/chwKP7BRdt5">recent acquisition</a> of Tourmaline Bio by Novartis for about $1.4 billion validates the importance of IL-6 therapeutics. The acquisition, announced earlier in September, includes Tourmaline’s Pacibekitug, a monoclonal antibody that targets IL-6, which is being evaluated as a treatment option for atherosclerotic cardiovascular disease.“With recent market developments, we feel it is an opportune time to explore TZLS-501’s development,” said Tiziana CEO Ivor Elrifi.TLSA stock nearly tripled in value this year.&nbsp;Read also:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/eli-lilly-terminates-study-of-bimagrumab-in-obesity/chDlEmYR34I">Eli Lilly Terminates A Study Of Bimagrumab In Obesity</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

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Tiziana Life Sciences Shares Rise On Advancing Second Asset Besides Foralumab: Retail Thinks Stock Has ‘So Much Potential’

Tiziana said that TZLS-501 may offer therapeutic advantages in managing acute and chronic inflammatory conditions.

Equity

Tiziana said that TZLS-501 may offer therapeutic advantages in managing acute and chronic inflammatory conditions.


AIM ImmunoTech, Inc. (1100% jump in message volume)AIM ImmunoTech surged in retail discussions after announcing the first new subject was dosed in Phase 2 of its Phase 1b/2 trial for Ampligen and AstraZeneca’s (AZN) Imfinzi in late-stage pancreatic cancer treatment. Several Phase 1 patients who received the highest dose will also be included in Phase 2. The trial, known as DURIPANC, is taking place in the Netherlands and will enroll up to 25 patients in this phase.PepGen, Inc. (700% jump in message volume)PepGen shares and retail chatter <a href="https://stocktwits.com/news-articles/markets/equity/pepgen-stock-heads-for-best-week-since-sept-2022/chdghv2RyH">soared</a> after the company released early clinical data from its FREEDOM-DM1 Phase 1 trial for PGN-EDODM1 in myotonic dystrophy type 1 (DM1), a genetic disorder causing progressive muscle weakness. The company reported dose-dependent splicing correction of 12.3% at 5 mg/kg and 29.1% at 10 mg/kg at 28 days post-dosing.While single-dose studies haven’t shown functional improvements, PepGen sees early signs of benefits with repeat dosing. H.C. Wainwright called the data “very encouraging.”Aeon Biopharma, Inc. (700% jump in message volume)Aeon gained attention after announcing a 1-for-72 reverse stock split to meet NYSE American’s minimum share price requirement. The move took effect on Wednesday, with fractional shares rounded up.Last month, Aeon received a non-compliance notice from NYSE American for failing to meet the $2 million stockholders’ equity requirement. The company reported a $32.1 million stockholders’ deficit as of Sept. 30 and has suffered losses in its last two fiscal years. Aeon has until March 5 to submit a plan to regain compliance.Tiziana Life Sciences Ltd. (600% jump in message volume)Tiziana’s stock buzz jumped after a Nature Neuroscience study showed its nasal anti-CD3 monoclonal antibody significantly reduced neuroinflammation and improved recovery in a preclinical model of traumatic brain injury (TBI). The treatment correlated with less anxiety, reduced cognitive decline, and improved motor skills.Additionally, Tiziana revealed on Tuesday that its nasal anti-CD3 preclinical study is nearing completion and that foralumab could be a novel treatment for long COVID.Moleculin Biotech, Inc.&nbsp;(600% jump in message volume)Moleculin saw heightened retail discussion after announcing a $1.07 per share direct offering of about 3.3 million shares and warrants to an institutional investor, with 6.5 million warrants exercisable at $1.07 per share for five years.The company&nbsp;expected to close the offering on Feb. 26, with Roth Capital Partners as the placement agent. The company said proceeds would be used for working capital and general corporate purposes.For updates and corrections, email newsroom[at]stocktwits[dot]com.

Hand holding test tube over stock data on computer monitor. | Image source: Getty Images

AIM ImmunoTech, PepGen, Aeon, Tiziana, Moleculin: 5 Biotech Stocks That Led Retail Message Growth Last Week

New trial data, a reverse split, and financing moves triggered a spike in retail chatter for these biotech stocks in the week ending Feb. 28, 2025.

Tiziana Life Sciences Ltd. is a clinical-stage biotechnology company, which engages in developing therapies for neurodegenerative and lung diseases. Its clinical pipeline includes drug assets for Secondary Progressive Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and Alzheimer’s. The company was founded by Gabriele Marco Antonio Cerrone on February 11, 1998 and is headquartered in London, the United Kingdom.

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