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Palantir Technologies, Inc. engages in the business of building and deploying software platforms that serve as the central operating systems for its customers. It operates through the Commercial and Government segments. The Commercial segment focuses on customers working in non-government industries. The Government segment is involved in providing services to customers that are the United States government and non-United States government agencies. Its platforms are widely used in areas such as defense, intelligence, healthcare, energy, and financial services, supporting data integration, large-scale analytics, and operational decision-making. The company was founded by Alexander Ceadmon Karp, Peter Andreas Thiel, Stephen Cohen, Joseph Lonsdale, and Nathan Dale Gettings in 2003 and is headquartered in Denver, CO.

Palantir Technologies Inc - Ordinary Shares - Class A

Palantir Technologies Inc

Palantir is trending due to mixed reactions following its earnings release and subsequent stock movement, with community members debating whether the stock is overvalued. A significant point of discussion is Michael Burry's reported short position against the company. Despite positive earnings news, the stock's high valuation and potential AI bubble concerns are driving bearish sentiment.

Uber Technologies, Inc. is a technology platform, which engages in the development and operation of technology applications, networks, and product to power movement from point A to point B. The firm offers ride services and merchants delivery service providers for meal preparation, grocery, and other delivery services. It operates through the following segments: Mobility, Delivery, and Freight. The Mobility segment refers to products that connect consumers with Mobility Drivers who provide rides in a variety of vehicles, such as cars, auto rickshaws, motorbikes, minibuses, or taxis. The Delivery segment offers consumers the chance to search for and discover local restaurants, order a meal, and either pick-up at the restaurant or have the meal delivered. The Freight segment focuses on connecting Carriers with Shippers on its platform, and gives Carriers upfront, transparent pricing, and the ability to book a shipment. The company was founded by Oscar Salazar Gaitan, Travis Kalanick, and Garrett Camp in 2009 and is headquartered in San Francisco, CA.

Uber Technologies Inc

Uber is trending as investors assess the implications of Q3 earnings, which included a massive EPS beat, even as some profit forecasts fell slightly short. The community is actively discussing the company's growth in bookings and trips, particularly the impact of Uber One memberships, while also debating whether the stock is currently undervalued given its market dominance and future potential in autonomous vehicles. Short-term manipulation and broader market conditions are also being considered as factors influencing the stock's price movement.

$WAGMI is a community-driven meme token built on the Solana blockchain, designed to bring positivity, unity, and humor into the crypto space. The project encourages community engagement through memes, social interaction, and token-based activities. It leverages Solana’s fast and low-cost infrastructure to allow for smooth on-chain interactions, such as token transfers, community games, and NFT integration. The goal is to foster a fun, inclusive ecosystem where holders feel they are part of a larger movement – "We Are Gonna Make It."

WAGMI

WAGMI CRYPTO is gaining attention, particularly within communities focused on the Solana ecosystem, with some users expressing bullish sentiment while others discuss challenges. The community emphasizes a shared vision and encourages building together, fostering a sense of unity despite market conditions.

Sarepta Therapeutics, Inc. is a commercial-stage biopharmaceutical company, which is engaged in the discovery and development of therapeutics for the treatment of rare diseases. The company was founded on July 22, 1980, and is headquartered in Cambridge, MA.

Sarepta Therapeutics Inc

Sarepta Therapeutics is trending amid discussions about a confirmatory trial and its potential impact on existing PMO therapies, which are facing scrutiny, while Elevidys sales remain a key focus. The community is weighing the implications for future revenue and potential FDA actions, with some speculating about a possible Roche buyout amid the uncertainty. Discussions also involve management's handling of recent data releases and their overall strategy.

Bitcoin is the first successful internet money based on peer-to-peer technology; whereby no central bank or authority is involved in the transaction and production of the Bitcoin currency. It was created by an anonymous individual/group under the name, Satoshi Nakamoto. The source code is available publicly as an open source project, anybody can look at it and be part of the developmental process.  Bitcoin is changing the way we see money as we speak. The idea was to produce a means of exchange, independent of any central authority, that could be transferred electronically in a secure, verifiable and immutable way. It is a decentralized peer-to-peer internet currency making mobile payment easy, very low transaction fees, protects your identity, and it works anywhere all the time with no central authority and banks.  Bitcoin is designed to have only 21 million BTC ever created, thus making it a deflationary currency. Bitcoin uses the SHA-256 hashing algorithm with an average transaction confirmation time of 10 minutes. Miners today are mining Bitcoin using ASIC chip dedicated to only mining Bitcoin, and the hash rate has shot up to peta hashes.  Being the first successful online cryptography currency, Bitcoin has inspired other alternative currencies such as Litecoin, Peercoin, Primecoin, and so on.  The cryptocurrency then took off with the innovation of the turing-complete smart contract by Ethereum which led to the development of other amazing projects such as EOS, Tron, and even crypto-collectibles such as CryptoKitties.

Bitcoin

Bitcoin's recent price volatility has the community debating whether a longer-term correction is underway. Some traders believe institutions are strategically selling off, while others see the dip as a bear trap before a potential rally toward previous highs. Discussions also involve the influence of broader market factors, such as the Nasdaq and potential government actions, on Bitcoin's price.

Zcash is a decentralized and open-source cryptocurrency that offers privacy and selective transparency of transactions. Zcash payments are published on a public blockchain, but the sender, recipient, and amount of a transaction remain private.  Zcash is based on peer-reviewed cryptographic research, and built by a security-specialized engineering team on an open source platform based on Bitcoin Core's battle-tested codebase. Our improvement over Bitcoin is the addition of privacy. Zcash uses advanced cryptographic techniques, namely zero-knowledge proofs, to guarantee the validity of transactions without revealing additional information about them.  How Zcash works  Zcash encrypts the contents of shielded transactions. Since the payment information is encrypted, the protocol uses a novel cryptographic method to verify their validity.  Zcash uses a zero-knowledge proof construction called a zk-SNARK, developed by our team of experienced cryptographers based on recent breakthroughs in cryptography. These constructions allow the network to maintain a secure ledger of balances without disclosing the parties or amounts involved. Instead of publicly demonstrating spend-authority and transaction values, the transaction metadata is encrypted and zk-SNARKs are used to prove that nobody is cheating or stealing.  Zcash also enables users to send public payments which work similarly to Bitcoin. With the support for both shielded and transparent addresses, users can choose to send Zcash privately or publicly. Zcash payments sent from a shielded address to a transparent address reveal the received balance, while payments from a transparent address to a shielded address protect the receiving value.   Check out CoinBureau for guide on What is ZCash.

Zcash

Zcash is trending amid discussions about its potential as a leading privacy coin and a hedge against Bitcoin's volatility, as some community members suggest it could reach new all-time highs. The conversations also highlight its upcoming anniversary, possibly leading to increased attention and speculation about future developments. Simultaneously, some traders are noting its overbought conditions and anticipating a potential pullback.

Pfizer Inc. is a research-based global biopharmaceutical company, which engages in the discovery, development, manufacture, marketing, sales and distribution of biopharmaceutical products worldwide. The firm works across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases. The company was founded by Charles Pfizer Sr. and Charles Erhart in 1849 and is headquartered in New York, NY.

Pfizer Inc.

Pfizer Inc

Pfizer is trending as community members assess the implications of recent earnings, raised guidance, and a notable dividend yield. Discussions include whether the market is undervaluing the stock, and speculation on potential acquisitions in the competitive obesity therapeutics market with some suggesting it may be a good long-term hold. Additionally, Michael Burry's position in PFE calls is generating buzz among investors.

JasmyCoin is based on the ERC 20 standard. The token can also be used by an unspecified number of individuals and businesses to transfer tokens using digital devices as proof of value exchange or payment for services. By not limiting its usability, the token can have a wide range of purposes.

JasmyCoin

JASMY is trending amidst mixed sentiment, with some traders citing potential partnerships and real-world utility while others express concerns about its price action and long-term viability. Community discussions revolve around identifying key resistance levels and whether the current market cap is justified. Speculation about future developments and potential catalysts continues to fuel the conversation.

Verastem, Inc. is a biopharmaceutical company, which engages in the development and commercialization of drugs for the treatment of cancer. The company was founded by Richard H. Aldrich, Michelle Dipp, Piyush Gupta, Satish Jindal, Eric S. Lander, Robert F. Weinberg, and Christoph H. Westphal on August 4, 2010 and is headquartered in Needham, MA.

Verastem Inc

Verastem ($VSTM) is trending as optimism grows around potential FDA approvals and encouraging clinical trial data, particularly in KRAS-mutant cancers. The community is actively discussing long-term prospects, potential buyouts, and comparisons to competitors in the oncology space. Bullish sentiment is fueled by expectations of significant valuation increases and potential for a short squeeze.

Shopify, Inc. is a global commerce company that provides essential internet infrastructure for commerce, offering trusted tools to start, scale, market, and run a retail business of any size. The Company's software enables merchants to run their business across all of their sales channels, including web and mobile storefronts, physical retail locations, social media storefronts and marketplaces. The Shopify platform provides merchants with a single view of their business across all of their sales channels and enables them to manage products and inventory, process orders and payments, fulfill and ship orders, build customer relationships, source products, leverage analytics and reporting and access financing, all from one integrated back office. The company was founded on September 28, 2004 and is headquartered in Ottawa, Canada.

Shopify Inc - Ordinary Shares - Class A (Sub Voting)

Shopify Inc

Shopify is trending as investors discuss the company's recent earnings report, which revealed revenue growth and cash flow positivity. Community members are debating whether the current valuation is justified amidst competition and broader market conditions. Some are optimistic about the company's future prospects, citing potential AI modeling and strategic partnerships with established brands.

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Upstream Bio (UPB) shares saw an increase in after-hours trading on Friday following the company's presentation of pharmacology modeling data, which showed investigational antibody verekitug as potentially more potent than tezepelumab by targeting the TSLP receptor rather than its ligand.Shares of the company finished at $11.36, down by 1.7%, but rose to $11.41 in after-hours trading with a 0.4% gain.Results from the European Academy of Allergy &amp; Clinical Immunology Congress demonstrated that verekitug produced lasting and thorough blockage of the TSLP/TSLPR complex, which drives critical inflammatory diseases, including severe asthma, as well as COPD and chronic rhinosinusitis with nasal polyps (CRSwNP).The FDA-approved antibody Tezspire (tezepelumab), which targets severe asthma, operates through TSLP ligand inhibition and was developed jointly by AstraZeneca and Amgen.The modeling study used a mechanistic PK/PD approach and incorporated clinical and published data.&nbsp;Simulations predicted that verekitug would lead to a greater reduction in fractional exhaled nitric oxide (FeNO)—a biomarker for airway inflammation—compared to tezepelumab.The company is looking to assess top-line Phase 2 data in CRSwNP later this year, and in severe asthma in the first half of 2026.”Verekitug is the only known monoclonal antibody in clinical development that directly targets the TSLP receptor, offering what the company describes as a more upstream and durable blockade of the inflammatory cascade.The stock moved higher after the release, with investors responding positively to the strengthened differentiation case for verekitug as it advances through multiple Phase 2 trials.&nbsp;These include the Valiant study in severe asthma, the Vibrant trial in CRSwNP, and a planned trial in COPD.Upstream Bio previously reported favorable tolerability, high subcutaneous bioavailability, and a consistent pharmacokinetic profile for verekitug in completed Phase 1 studies.On Stocktwits, retail sentiment was ‘neutral’ amid ‘high’ message volume.Upstream’s stock has declined 30.3% so far in 2025.For updates and corrections, email newsroom[at]stocktwits[dot]com.

Portrait of a doctor woman on the background of stock charts. | Image source: Getty Images

Upstream Bio Stock Gets A Boost As New Lung Inflammation Drug Shows Higher Potency

The company is progressing with multiple Phase 2 trials for its investigational treatment targeting severe respiratory diseases.

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Automotive Security Leaders Must Take Immediate Action to Mitigate the Surging Cyber Threats--Upstream Report Reveals Critical Gaps

Automotive Security Leaders Must Take Immediate Action to Mitigate the Surging Cyber Threats--Upstream Report Reveals Critical Gaps Automotive Security Leaders Must Take Immediate Action to Mitigate...

Upstream Bio, Inc. is a clinical-stage biotechnology company, which engages in the development of treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. It develops verekitug, the only known antagonist currently in clinical development that targets the receptor for Thymic Stromal Lymphopoietin. The company was founded in April 2021 and is headquartered in Waltham, MA.

Upstream Bio Inc.

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Current Price	$25.02
Prev Close	$25.85
Open	$25.92
Dividend Yield	0.00%
50-Day Moving Average	$19.49
Beta	1.16
Avg. Volume	353,554.13
PE Ratio	-12.20

52-Week High	$29.46
52-Week Low	$5.14
Market Capitalization	$1.35B
EPS (Annual)	-$1.43
Price to Book	3.29
Revenue Per Employee	$45,576.92
Enterprise Value/EBITDA	N/A

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