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RAGE GUY (RAGE) is a cryptocurrency inspired by the Rage Guy meme, one of the earliest and most recognizable characters from internet rage comics. The project captures the cultural legacy of early meme history and brings it onto the blockchain in tokenized form. It is designed as a community-driven digital asset that celebrates internet culture, nostalgia, and the role memes play in shaping online communities.

Rage Guy

$RAGE is trending as the community rallies around the revival of 'OG Memes' and a return to the '2021 vibes', with community members highlighting its strong base and potential for substantial growth following recent market events. Active discussions center on potential exchange listings and the overall revival of Rage Comics. The community emphasizes conviction and actively 'working for their bags' in the current market.

Memecoin on Cronos launched by the Cro Crow community

crow with knife

CAW CRYPTO, also known as crow with knife, is trending as the community rallies around its meme-driven identity and organic, community-led development. The focus is on strong community and the coin's multichain functionality. Bullish sentiment is high, with many urging others to "buy more caw" and highlighting the project's burn mechanism.

DOVU

DOVU is trending as the community buzzes about staking rewards and potential listings, with some highlighting its role in Real World Asset (RWA) tokenization on the Hedera network. Recent partnerships and developments around DOVU OS, particularly within the ecological credit space, have also sparked interest. Talk within the community highlights DOVU's potential within the Hedera ecosystem.

Algorand is a scalable, secure, and decentralized digital currency and smart contract platform. Its protocol uses a variation of Proof-of-Stake (PoS) called Pure PoS (PPoS) to secure the network and reach consensus on block production. Developers can build decentralized applications (dApps) using familiar programming languages, including Python, which Algorand supports natively. Its infrastructure enables various use cases, including payment systems, digital identity solutions, supply-chain tracking, and financial services. The protocol's architecture allows for tokenization of assets and the development of smart contracts, while its technical specifications support both retail users seeking basic transaction capabilities and enterprises requiring more, complex, blockchain solutions.

Algorand

ALGO is trending as the community debates its future amid fluctuating prices and a broader crypto market downturn, with some fearing it may reach new all-time lows. Discussions include the Algorand Foundation's actions and potential token supply adjustments, which are causing concern for some investors. However, others remain optimistic, pointing to long-term potential, staking rewards, and developments within the Algorand ecosystem, such as new projects and partnerships.

Hedera is a decentralized public network where developers can build secure, fair applications with near real-time consensus. The platform is owned and governed by a council of global innovators including Avery Dennison, Boeing, Deutsche Telekom, DLA Piper, FIS (WorldPay), Google, IBM, LG Electronics, Magalu, Nomura, Swirlds, Tata Communications, University College London (UCL), Wipro, and Zain Group.   The Hedera Consensus Service (HCS) acts as a trust layer for any application or permissioned network and allows for the creation of an immutable and verifiable log of messages. Application messages are submitted to the Hedera network for consensus, given a trusted timestamp, and fairly ordered. Use HCS to track assets across a supply chain, create auditable logs of events in an advertising platform, or even use it as a decentralized ordering service.

Hedera Hashgraph

HBAR is trending as the community debates its potential amid a broader crypto downturn, with some expressing concerns about its price action and tokenomics.  Discussion includes comparison with other cryptos and speculation about accumulation by large holders, while others highlight potential Keeta partnerships and broader enterprise-level distributed ledger solutions.

SAP SE engages in the provision of enterprise application software and software-related services. It operates through the following segments: Applications, Technology, and Support; Qualtrics; and Services. The Applications, Technology, and Services segment includes sale of software licenses, support offerings, and cloud subscriptions. The Qualtrics segment sells experience management cloud solutions. The Services segment offers professional services, premium support services, implementation services for software products, and education services on the use of products. The company was founded by Hasso Plattner, Klaus Tschira, Claus Wellenreuther, Dietmar Hopp, and Hans-Werner Hector on April 1, 1972 and is headquartered in Walldorf, Germany.

Sap SE - ADR

SAP AG

SAP is trending as the company expands its alliances to strengthen its cloud and AI solutions in Europe, with community members discussing the potential impact on digital sovereignty. Some traders are also noting constructive premarket flow, while others point to concerns about SAP's competitive practices and valuation. Palantir ($PLTR) is also heavily mentioned by the community, often in direct comparison to SAP's AI offerings.

Amplify ETF Trust - Amplify Seymour Cannabis ETF

Amplify Seymour Cannabis ETF

Amplify Seymour Cannabis ETF ($CNBS) is trending as cannabis stocks are reacting to potential regulatory shifts, including speculation around federal policy changes. The community is weighing the potential impacts of these changes on the sector, while also considering structured approaches to cannabis exposure. Discussion includes analysis of top holdings and the ETF's positioning within the broader cannabis market.

Loopring is a Decentralized Exchange (DEX) built on an Ethereum Layer-2 (L2) solution called zkRollup. It has both Automated Market Maker (AMM)-based and orderbook-based exchanges.   zkRollup is an Ethereum L2 scaling solution that migrates computations off the blockchain. Loopring protocol only uses the underlying Ethereum blockchain as a data layer and a verification layer. As a result, Loopring's throughput is as high as 2,025 trades per second compared to Ethereum’s current throughput of 15 transactions per second. The result is that the cost per trade settlement is as small as $0.00015.  Loopring's performance is sufficient for professional traders and market makers to deploy algorithmic strategies and other automated trading bots. This was not previously possible on any DEX as it was prohibitively slow and expensive. By building on top of Loopring 3.0, orderbook-based DEXs can be commercially viable for the first time. Loopring expects non-custodial exchanges can begin to outcompete and displace many centralized counterparts.

Loopring

Loopring is trending as community members discuss potential AI-related news catalysts and possible short squeezes. Bullish sentiment is fueled by anticipation of a major price movement, with some eyeing targets significantly higher. However, there are also mentions of past disappointments and skepticism about its ability to keep pace with broader market gains.

ARB IOT Group Ltd. is a holding company that engages in the provision of solutions for the integration of IoT systems and devices. It operates through the Internet of Things and Investment Holding and Others segments. The company was founded on March 1, 2022 and is headquartered in Singapore.

ARB IOT Group Ltd

ARBB is trending due to community excitement around its low float and potential for a short squeeze, with comparisons being drawn to similar past runners. The renewed interest seems to be fueled by social media speculation regarding a previous AI server deal and the company's reverse split. Traders are closely watching key price levels to determine potential for further upward momentum.

Digimarc Corp. provides digital watermarking technology services. It develops solutions, licenses intellectual property, and provides development services. The company also connects print, audio, and packaging to brand-defined online content, protects, identifies, and tracks digital files, and confirms content and objects are genuine, unaltered, and from an authorized source. Its products include Digimarc Validate, Digimarc Engage, Digimarc Recycle and Digimarc Retail Experience. The company was founded on January 3, 1995 and is headquartered in Beaverton, OR.

Digimarc Corporation

Digimarc ($DMRC) is trending amid ongoing discussions about a major contract, potentially with Walmart ($WMT), driving speculation and optimism within the community. Despite positive sentiments and potential applications of Digimarc's technology, concerns linger around leadership, execution, and past promises, contributing to community skepticism. Investor focus remains on upcoming earnings and updates regarding strategic partnerships.

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Norges Bank Acquires New Position in Upstream Bio, Inc. $UPB

Norges Bank bought a new position in shares of Upstream Bio, Inc. (NASDAQ:UPB - Free Report) in the 2nd quarter, according to its most recent 13F filing with the Securities & Exchange Commission. The...

Geode Capital Management LLC Buys 235,958 Shares of Upstream Bio, Inc. $UPB

Geode Capital Management LLC boosted its stake in Upstream Bio, Inc. (NASDAQ:UPB - Free Report) by 57.5% in the second quarter, according to the company in its most recent 13F filing with the...

Upstream Bio (NASDAQ:UPB) Shares Up 8.5% - Should You Buy?

Upstream Bio (NASDAQ:UPB) Shares Up 8.5% - Time to Buy...

Upstream Bio (NASDAQ:UPB) Hits New 12-Month High - What's Next?

Upstream Bio (NASDAQ:UPB) Reaches New 12-Month High - Still a Buy...

Evercore ISI Begins Coverage on Upstream Bio (NASDAQ:UPB)

Evercore ISI assumed coverage on shares of Upstream Bio in a research note on Tuesday. They set an "outperform" rating and a $40.00 price objective for the company...

Upstream Bio (NASDAQ:UPB) Announces Earnings Results

Upstream Bio (NASDAQ:UPB - Get Free Report) issued its earnings results on Wednesday. The company reported ($0.63) earnings per share for the quarter, topping analysts' consensus estimates of ($0.78...

Upstream Bio (UPB) shares saw an increase in after-hours trading on Friday following the company's presentation of pharmacology modeling data, which showed investigational antibody verekitug as potentially more potent than tezepelumab by targeting the TSLP receptor rather than its ligand.Shares of the company finished at $11.36, down by 1.7%, but rose to $11.41 in after-hours trading with a 0.4% gain.Results from the European Academy of Allergy &amp; Clinical Immunology Congress demonstrated that verekitug produced lasting and thorough blockage of the TSLP/TSLPR complex, which drives critical inflammatory diseases, including severe asthma, as well as COPD and chronic rhinosinusitis with nasal polyps (CRSwNP).The FDA-approved antibody Tezspire (tezepelumab), which targets severe asthma, operates through TSLP ligand inhibition and was developed jointly by AstraZeneca and Amgen.The modeling study used a mechanistic PK/PD approach and incorporated clinical and published data.&nbsp;Simulations predicted that verekitug would lead to a greater reduction in fractional exhaled nitric oxide (FeNO)—a biomarker for airway inflammation—compared to tezepelumab.The company is looking to assess top-line Phase 2 data in CRSwNP later this year, and in severe asthma in the first half of 2026.”Verekitug is the only known monoclonal antibody in clinical development that directly targets the TSLP receptor, offering what the company describes as a more upstream and durable blockade of the inflammatory cascade.The stock moved higher after the release, with investors responding positively to the strengthened differentiation case for verekitug as it advances through multiple Phase 2 trials.&nbsp;These include the Valiant study in severe asthma, the Vibrant trial in CRSwNP, and a planned trial in COPD.Upstream Bio previously reported favorable tolerability, high subcutaneous bioavailability, and a consistent pharmacokinetic profile for verekitug in completed Phase 1 studies.On Stocktwits, retail sentiment was ‘neutral’ amid ‘high’ message volume.Upstream’s stock has declined 30.3% so far in 2025.For updates and corrections, email newsroom[at]stocktwits[dot]com.

Portrait of a doctor woman on the background of stock charts. | Image source: Getty Images

Upstream Bio Stock Gets A Boost As New Lung Inflammation Drug Shows Higher Potency

The company is progressing with multiple Phase 2 trials for its investigational treatment targeting severe respiratory diseases.

Equity

Upstream Bio, Inc. is a clinical-stage biotechnology company, which engages in the development of treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. It develops verekitug, the only known antagonist currently in clinical development that targets the receptor for Thymic Stromal Lymphopoietin. The company was founded in April 2021 and is headquartered in Waltham, MA.

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