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Eli Lilly & Co. engages in the discovery, development, manufacture, and sale of pharmaceutical products. The firm's products include diabetes, oncology, immunology, neuroscience, and other products and therapies. The company was founded by Eli Lilly on May 10, 1876 and is headquartered in Indianapolis, IN.

Lilly(Eli) & Co

Encouraging early-stage ESMO results for Lillys investigational ovarian-cancer drug Sofe-M plus bevacizumab are drawing attention, with traders viewing the oncology pipeline as diversification beyond obesity treatments. The findings come from a small study, so their broader significance remains uncertain.

BioNTech SE operates as immunotherapy company, which engages therapies for cancer and other serious diseases. Its product pipeline include BNT162b2, BNT161, BNT164, FixVac, iNeST, RiboMabs, CAR-T Cells, TCRs and Next-Gen CP Immunomodulators. The company was founded by Christopher Huber, Oezlem Tuereci, and Ugur Sahin on June 2, 2008 and is headquartered in Mainz, Germany.

BioNTech SE - ADR

BioNTech and Bristol Myers Squibbs Phase 2 pumitamig-plus-docetaxel results in advanced NSCLC are drawing attention, with traders focused on the response and progression-free-survival signal after prior immunotherapy and chemotherapy. The main question is whether the benefit will prove durable in later analyses.

Ouster, Inc. engages in the provision of high resolution digital lidar sensors that offer advanced 3D vision to machinery, vehicles, robots, and fixed infrastructure assets. The company was founded by Angus Pacala and Mark Frichtl on June 30, 2015 and is headquartered in San Francisco, CA.

Ouster Inc - Ordinary Shares - Class A

OUST is drawing attention for its sharp, volatile pullback, which traders variously blame on weakness in high-beta growth stocks or see as a buying opportunity. Bulls cite expanding lidar deploymentsincluding planned use of Rev8 sensors in John Deeres autonomous orchard machinesas support for Ousters Physical AI growth story, while skeptics question valuation, adoption and profitability.

Coinbase Global, Inc. engages in the provision of a trusted platform that serves as a compliant on-ramp to the onchain economy and enables users to engage in a wide variety of activities with their crypto assets in both proprietary and third-party product experiences enabled by access to decentralized applications. It offers consumers primary financial account for the cryptoeconomy, institutions a full-service prime brokerage platform with access to deep pools of liquidity across the crypto marketplace, and developers a suite of products granting access to build onchain. The company was founded by Brian Armstrong and Fred Ernest Ehrsam in May 2012 and is headquartered in New York, NY.

Coinbase Global Inc - Ordinary Shares - Class A

Coinbase Global Inc

Coinbase is drawing attention for its weakness and repeated underperformance versus Bitcoin and other crypto-linked stocks amid volatile crypto prices. Traders debate whether the slide is mainly crypto-driven or reflects company-specific concerns, with Q3 results and revenue trends also in focus.

Johnson & Johnson is a holding company, which engages in the research, development, manufacture, and sale of products in the healthcare field. It operates through the Innovative Medicine and MedTech segments. The Innovative Medicine segment focuses on immunology, infectious diseases, neuroscience, oncology, cardiovascular and metabolism, and pulmonary hypertension. The MedTech segment includes a portfolio of products used in interventional solutions, orthopaedics, surgery, and vision categories. The company was founded by Robert Wood Johnson I, James Wood Johnson, and Edward Mead Johnson Sr. in 1887 and is headquartered in New Brunswick, NJ.

Johnson & Johnson

Positive prostate-cancer trial results including a reported reduction in recurrence risk and a strong tumor response rateare driving attention to J&Js oncology pipeline. Traders are weighing whether the data can support further gains or is already priced in, with some watching whether shares hold their recent advance.

Kratos Defense & Security Solutions, Inc. engages in the provision of mission critical products, services and solutions for United States national security priorities. It operates through the Kratos Government Solutions (KGS) and Unmanned Systems (US) segments. The KGS segment consists of an aggregation of KGS operating segments, including microwave electronic products, space, satellite and cyber, training solutions. The US segment refers to the unmanned aerial, unmanned ground, unmanned seaborne and related command, control and communications system businesses. The company was founded on December 19, 1994, and is headquartered in Round Rock, TX.

Kratos Defense & Security Solutions Inc

Kratos is drawing attention for its steep selloff toward 52-week lows, despite reported contract wins and analyst upgrades. Traders are split between viewing the weakness as an oversold buying opportunity and worrying about valuation, insider selling, and whether production growth can translate into stronger margins and cash flow.

Galaxy Digital, Inc. engages in digital assets and data center infrastructure, delivering solutions that accelerate progress in finance and artificial intelligence. It operates through the following segments: Digital Assets, Data Centers, and Treasury and Corporate. The digital assets segment offers institutional access to trading, advisory, asset management, staking, self-custody, and tokenization technology. The Data Centers segment competes with a range of infrastructure providers that are building or repurposing facilities to support the rapidly growing demand for AI and compute-intensive workloads. The Treasury and Corporate segment includes the company’s proprietary trading and mining activities, as well as the company’s principal investments and related gains and losses. The company was founded by Michael Novogratz in 2018 and is headquartered in New York, NY.

Galaxy Digital Inc. - Ordinary Shares - Class A

GLXY is under pressure amid weakness across crypto and AI/data-center stocks, with traders focused on upcoming earnings and worried about the companys CoreWeave exposure and lack of further tenant news. Sentiment is largely bearish, though some traders see the selloff as overdone and expect earnings or a tenant update to offer support.

Shiba Inu (SHIB) is a decentralized, community-led cryptocurrency ecosystem built on the Ethereum blockchain. Originally launched as a meme-based project, it has evolved into a comprehensive financial ecosystem designed to offer a decentralized alternative to traditional banking. Its main value proposition lies in its transition from a social phenomenon into a functional utility network, supported by a vast global community known as the ShibArmy and a commitment to 100% community ownership with no central leadership.  The ecosystem features its own decentralized exchange, ShibaSwap, where users can trade, provide liquidity, and earn rewards. To address Ethereum’s high costs and slow speeds, the project utilizes Shibarium, a Layer 2 scaling solution that processes transactions faster and more affordably.  The project employs a unique three-token model to manage its economy and governance. SHIB serves as the primary currency for trading and payments, while LEASH offers scarcity-based incentives for dedicated supporters. BONE acts as the governance token, allowing holders to vote on proposals through the Doggy DAO and serving as the native gas token for the Shibarium network.

Shiba Inu

SHIB is drawing attention for its prolonged sideways, choppy trading, with repeated technical posts describing consolidation and traders watching for a breakout. The community is split between dip-buying and hopes for a meme-coin rally versus frustration over weak momentum, declining-price concerns, and questions about token utility and burns.

Caterpillar, Inc. engages in the business of manufacturing construction and mining equipment, off-highway diesel and natural gas engines, industrial gas turbines, and diesel-electric locomotives. It operates through the following segments: Construction Industries, Resource Industries, Power and Energy, and All Other. The Construction Industries segment is involved in supporting customers using machinery in infrastructure and building construction applications. The Resource Industries segment offers machinery in mining, heavy construction, quarry, and aggregates. The Power and Energy segment focuses on reciprocating engines, turbines, diesel-electric locomotives, and related services across industries serving oil and gas, power generation, industrial, and transportation applications including marine- and rail-related businesses. The All Other segment includes activities such as the business strategy, product management and development, manufacturing, and sourcing of wear and maintenance components products, parts distribution, integrated logistics solutions, distribution services responsible for dealer development, and administration. The company was founded on April 15, 1925, and is headquartered in Irving, TX.

Caterpillar Inc.

Caterpillars steep pullback has traders debating whether oversold conditions and support will attract dip buyers or whether the decline has further to run. The upcoming earnings report is seen as a key test of whether strong backlog and AI/data-center power demand can offset concerns about softer guidance and slowing investment.

Cisco Systems, Inc. engages in the design, manufacture, and sale of Internet Protocol-based networking products and services related to the communications and information technology industry. The firm operates through the following geographical segments: the Americas, EMEA, and APJC. Its products include the following categories: Secure, Agile Networks, Internet for the Future, Collaboration, End-to-End Security, Optimized Application Experiences, and Other Products. The company was founded by Sandra Lerner and Leonard Bosack in 1984 and is headquartered in San Jose, CA.

Cisco Systems, Inc.

Ciscos shares have drawn attention amid a prolonged pullback despite solid results and AI-networking demand, with traders pointing to Piper Sandlers reduced price target and concerns about peak growth and valuation as possible reasons for weakness. Bulls counter that AI infrastructure demand supports the business and view the decline as a buying opportunity, while many traders remain frustrated by the stocks sluggish, range-bound action.

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XLEI leads a pack of high-yield energy ETFs as oil volatility and Middle East tensions keep income-focused funds in the spotlight.

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Energy ETFs are likely to remain strong, as oil prices are unlikely to return to pre-war levels even if an Iran war truce materializes, keeping high-yield funds in focus.

After 47 Years, US And Iran Begin Direct Talks While US Vice President Vance Leads Negotiations

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According to Al Jazeera, Israeli air attacks in southern Lebanon killed civilians and emergency personnel while negotiation talks took place in Pakistan.

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<ul class="summary-bullets"><li>Vice President JD Vance and top officials met Iranian counterparts in Islamabad for the first direct discussions since 1979.&nbsp;</li><li>The Pakistan-mediated “Islamabad Talks” transitioned from indirect to face-to-face discussions, aiming to transform a weak truce into a lasting deal.</li><li>Lebanon tensions impacted diplomacy, with Israeli attacks reportedly killing civilians and PM Salam postponing a US-UN trip due to the turmoil.</li></ul>US Vice President JD Vance and senior American officials have held direct, face-to-face talks with an Iranian delegation in Islamabad, the White House confirmed—marking the first such high-level engagement between the two countries since Iran’s 1979 Islamic Revolution, a gap of 47 years.The White House reportedly <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.bbc.com/news/live/cn4v0xm9y0kt">confirmed</a> that US Vice President JD Vance and top officials met with an Iranian team in Islamabad, the first high-level contact between the two nations since Iran's 1979 Islamic Revolution, according to reports.The Associated Press <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://apnews.com/article/iran-us-israel-trump-lebanon-april-11-2026-2be904aee3f804892336730279e054b9">reported</a> that Vance met with Iranian officials in person as part of the high-stakes diplomatic effort. The US team included envoys Steve Witkoff and Jared Kushner, signifying an increase in Washington's role. The direct interaction marks a significant step after weeks of indirect conversations mediated by Pakistan, with both parties now talking face-to-face for the first time in decades.<h2 class="st-heading-2">Vance Arrives For ‘Make-or-Break’ Talks</h2>Vance arrived in Pakistan earlier on Saturday to oversee efforts to resolve the US-Israeli crisis with Iran. <a href="https://stocktwits.com/news-articles/markets/equity/us-iran-peace-talks-stop-america-first-stance/cZJjkpZRIMe">The "Islamabad Talks,"</a> led by Pakistan, are seen as a key effort to transform a fragile truce into a long-term accord. Pakistan has positioned itself as a crucial mediator, holding delegations under strict security as it seeks a long-term settlement.Developments in Lebanon continue to cast a pall on the talks.According to an Al Jazeera&nbsp;<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.aljazeera.com/news/liveblog/2026/4/11/iran-war-live-us-negotiators-due-to-arrive-in-pakistan-for-ceasefire-talks">report</a>, Israeli air strikes in southern Lebanon killed civilians and emergency professionals, including a paramedic and a member of the Lebanese Civil Defense, in the towns of Kfar Sir, Zefta, and Toul in the Nabatieh area. Lebanese Prime Minister Nawaf Salam <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://x.com/nawafsalam/status/2042959998603452658">announced</a> on Saturday that has postponed a scheduled trip to the United Nations and the United States due to the "current internal situation" in Lebanon, adding to political tensions.<figure class="image"><a class="st-link-external" href="https://x.com/nawafsalam/status/2042959998603452658" target="_blank" rel="noopener noreferrer nofollow"><img src="https://news.stocktwits-cdn.com/Screenshot_2026_04_11_at_12_29_35_PM_png_4b47cd4db5.webp" alt="Screenshot 2026-04-11 at 12.29.35 PM.png" width="804" height="334"></a><figcaption>Lebanese Primie Minister on postponing trip to USA and the United nations. Source: @@nawafsalam/x</figcaption></figure><a href="https://stocktwits.com/symbol/QQQ">The Invesco QQQ ETF (QQQ)</a>, which tracks the performance of the Nasdaq-100 Index, ended Friday essentially flat at around $610, slipping marginally by about 0.01% on the day.&nbsp;<a href="https://stocktwits.com/symbol/XLE">Street Street Energy Select Sector SPDR ETF (XLE)</a>, a benchmark ETF for US energy stocks that is heavily tied to oil prices and energy demand trends, underperformed, closing down roughly 0.68% to $56.94, reflecting weakness in energy stocks. Meanwhile, the <a href="https://stocktwits.com/symbol/USO">United States Oil Fund (USO)</a> closed down about 1.69% on Friday.Get updates to this story developing directly on Stocktwits.Read also:&nbsp;<a href="https://stocktwits.com/news-articles/markets/cryptocurrency/trumplinked-wlfi-crashes-to-record-low/cZJj8WaRIMB">Trump-Linked WLFI Crashes To Record Low After $150M Borrowing Raises Red Flags</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

Pakistani Premier Sharif holds talks with Iranian delegation. (Photo by Iranian Foreign Ministry/Handout/Anadolu via Getty Images)

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