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Cadrenal Therapeutics, Inc. is a clinical-stage biopharmaceutical company, which engages in developing novel therapy. It develops tecarfarin, a novel therapy with orphan drug indication, designed for the prevention of systemic thromboembolism of cardiac origin in patients with end-stage renal disease and atrial fibrillation. The company was founded by Quang X. Pham and Matthew K. Szot on January 25, 2022 and is headquartered in Ponte Vedra, FL.

Cadrenal Therapeutics Inc

Cadrenal Therapeutics, Inc.

Cadrenal Therapeutics (CVKD) is trending due to recent pipeline expansion with VLX-1005 for heparin-induced thrombocytopenia and ongoing progress for its lead candidate tecarfarin, including manufacturing readiness and a collaboration with Abbott for its Phase 3 trial. The community is sharply divided, with bulls highlighting the potential for a "warfarin replacement" and analyst price targets, while skeptics point to cash burn concerns, dilution risk, and accusations of bot-driven pumping.

USA Rare Earth, Inc. is domestic supplier of rare earth magnets and heavy rare earth elements. It is developing a vertically integrated, domestic supply chain for rare earth element magnet production, with a facility in Stillwater, Oklahoma, and mining rights to the Round Top heavy rare earth and critical minerals deposit in West Texas. The company was founded in May 2019 and is headquartered in Stillwater, OK.

USA Rare Earth Inc. - Ordinary Shares - Class A

USA Rare Earth Inc

USA Rare Earth is currently a major talking point following reports of a substantial US government investment, including an equity stake and a significant loan, aimed at securing domestic critical mineral supply. The community is highly bullish, anticipating a massive price surge and potential short squeeze, drawing comparisons to other rare earth stocks that previously received government backing. This strategic move highlights ongoing efforts to reduce reliance on foreign nations for essential resources, intensely fueling discussions around USAR's future valuation.

A project grown out of the community's love and passion for the weed culture. Launched around early 2025, $weedcoin, “Like Bitcoin but way higher,” emphasizes its alignment with cannabis culture and a laid-back vibe. Unlike other Weed communities, this project leans heavily into community engagement over technical utility, aiming to build a “stoner community” through social media presence and decentralized governance. We also aim to focus on onboarding web2 businesses and users onto web3 through the token.

Weedcoin

Weedcoin is currently trending, driven by its community's emphasis on a patient, culture-first approach within the Solana ecosystem. Discussions frequently highlight its alignment with the global cannabis movement and the long-term potential of hemp-related innovation, often expressed as being "like Bitcoin, but way higher." The community values steady growth and collective belief, embodying a "Bongterm" commitment rather than short-term hype.

Avino Silver & Gold Mines Ltd. engages in the mining and exploration activities. It focuses on silver reserves in the Durango region of North Central Mexico. It operates through the Silver, Gold, and Copper segments. The company was founded on May 15, 1968 and is headquartered in Vancouver, Canada.

Avino Silver & Gold Mines Ltd.

Avino Silver & Gold Mines is trending as a key beneficiary of the ongoing silver rally, with robust production growth and a strengthened balance sheet positioning it for significant upside. Investors are actively discussing its perceived undervaluation compared to surging metal prices and the anticipated impact of the fully owned La Preciosa project, expecting exponential margin expansion and a sector re-rating.

SentinelOne, Inc. engages in the provision of endpoint security software that detects, models, and predicts threat behavior to block attacks on any computing device. Its services include vigilance, support, and training. The company was founded by Tomer Weingarten and Almog Cohen in 2013 and is headquartered in Mountain View, CA.

SentinelOne Inc - Ordinary Shares - Class A

SentinelOne Inc

SentinelOne (S) is trending following its recent earnings report, which, despite strong revenue growth and improved profitability, led to a notable stock drop, with conservative guidance being a key point of community discussion. Investors are actively debating whether the stock is severely undervalued in the growing cybersecurity sector, frequently pointing to its robust balance sheet and expressing hopes for a potential acquisition. Much of the conversation reflects a strong belief in the company's long-term potential contrasting with its current low valuation, fueling speculation about market manipulation.

Visa, Inc. engages in the provision of digital payment services. It also facilitates global commerce through the transfer of value and information among a global network of consumers, merchants, financial institutions, businesses, strategic partners, and government entities. It offers debit cards, credit cards, prepaid products, commercial payment solutions, and global automated teller machines. The company was founded by Dee Hock in 1958 and is headquartered in San Francisco, CA.

Visa Inc - Ordinary Shares - Class A

Visa Inc

Visa is a trending topic amidst market chatter regarding proposed credit card interest rate caps and competition legislation. However, the community widely believes these measures will not directly impact Visa's core transaction-based revenue, as the company continues to showcase robust payments volume and strategic expansion into stablecoin settlements and AI-driven commerce. Investors are actively highlighting Visa's durable business model and its proactive innovations in the evolving digital payments ecosystem.

Dog (Bitcoin) is a fully decentralized memecoin on the Bitcoin blockchain, backed by a community dedicated to onboarding millions of people to Bitcoin.  Dog is secured by the Bitcoin blockchain and exists on Bitcoin L1, marking a significant innovation compared to Bitcoin with just BTC. Dog is a Bitcoin Runes token with a minimal on-chain footprint, native to Bitcoin, and stored in UTXOs, just like Bitcoin.   What is the project about?  Dog does not do any paid promotion and is fully decentralized just like Bitcoin. Every influencer who chooses to post about Dog either received the airdrop or bought on secondary. Dog leverages the CC0 license to ensure that Dog is not owned by any single entity but rather by everyone. This had lead to the "DOG Army" independently creating art, apps, lotteries, plushies, websites, podcast, magazines, X account, IRL meetups, clothing lines, PFP collections, Telegram groups, and TikTok/Instagram about Dog.  What makes your project unique?  Dog was airdropped in the fairest memecoin launch ever. In early 2024, the Bitcoin Ordinals ecosystem came together in a full volunteer initiative that rewarded early adopters of the Ordinals Protocol. There was no team allocation, and 100% of the supply was airdropped for free. The airdrop algorithm favored neither whales nor influencers; it was determined by the community and made open-source for maximum transparency.

Dog (Bitcoin)

DOG CRYPTO is currently trending due to widespread excitement over its reported rollout on Coinbase, indicating a major expansion opportunity for the Bitcoin-native memecoin. The community strongly emphasizes its fixed supply and direct integration with the Bitcoin network as key differentiators, touting its inherent security and unique position. Holders express conviction that this foundational strength, combined with its recent momentum, points towards significant long-term growth within the crypto ecosystem.

Satellogic, Inc. operates as a vertically integrated geospatial company. It is creating and continuously enhancing the first scalable, fully automated EO platform with the ability to remap the entire planet at both high-frequency and high-resolution, providing accessible and affordable solutions for customers. The company was founded by Emiliano Kargieman and Gerardo Richarte in July 2010 and is headquartered in Davidson, NC.

Satellogic Inc - Ordinary Shares - Class A

Satellogic is trending amidst growing anticipation of significant contract awards for its high-resolution satellite imagery, fueled by its strong connections within the defense and government sectors. The community is actively discussing its potential as an undervalued space play, drawing comparisons to established industry leaders and highlighting recent successful satellite launches and strategic agreements as key drivers for future growth and partnerships with major players in the tech and space ecosystem.

Sigma Lithium Corp. engages in the producing of a lithium property. It focuses its project in Minas Gerais. The firm also plans to build a world-class commercial-scale lithium concentration plant. The company was founded on June 8, 2011 and is headquartered in Sao Paulo, Brazil.

Sigma Lithium Corporation

Sigma Lithium is trending due to its recent sale of high-purity lithium fines at a premium, coupled with clarifications addressing past operational concerns. The community is actively discussing renewed bullish sentiment in the broader lithium market, driven by surging lithium futures prices and a forecasted demand increase, leading many to anticipate significant upside and potential short covering for SGML.

American Airlines Group, Inc. is a holding company, which engages in the operation of a network carrier through its principal wholly owned mainline operating subsidiary, American. The firm offers air transportation for passengers and cargo. It operates through the following geographical segments: Domestic, Latin America, Atlantic, and Pacific. The company was founded on December 9, 2013, and is headquartered in Fort Worth, TX.

American Airlines Group Inc

American Airlines is trending as a major winter storm and an urgent Airbus A320 software recall lead to extensive flight cancellations and operational disruptions. The community is actively discussing these challenges, with some traders viewing current price action as a "Blue Box" buying opportunity, while others remain cautious ahead of the airline's anticipated earnings report.

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180 Life Sciences Corp, which is rebranding as ETHZilla, drew heavy retail interest on Tuesday after revealing that it holds $349 million worth of Ethereum and about $238 million in cash equivalents, alongside a recent 7.5% stake disclosure from billionaire investor Peter Thiel.The stock more than tripled to $6.9 on Tuesday, hitting a 10-month high, and added another 6.7% in after-hours trading.The company stated that it owns 82,186 Ether (ETH) at an average purchase price of $3,806.71, with recent acquisitions intended for long-term holding and staking through Electric Capital’s proprietary strategies, which aim to generate yield.&nbsp;Executive Chairman McAndrew Rudisill said more than $350 million had been deployed since closing a $425 million private investment in public equity (PIPE) deal last week.ETHZilla’s treasury strategy is based on plans announced on July 29 to make Ether its principal reserve asset, managed through an on-chain yield generation program designed to outperform traditional ETH staking.&nbsp;The PIPE deal drew more than 60 institutional and crypto-native investors, including Electric Capital, Polychain Capital, GSR, and Ethereum ecosystem founders such as Konstantin Lomashuk, Sreeram Kannan, and Robert Leshner.The Palo Alto-based company said its DeFi Council, comprising capital markets veterans, engineers, and protocol founders, will advise on strategies that combine staking, lending, liquidity provision, and private agreements.&nbsp;ETHZilla stated that it aims to establish itself as a benchmark for on-chain treasury management among public companies.In a regulatory filing with the U.S. Securities and Exchange Commission&nbsp;late Monday, Thiel reported beneficial ownership of 11.6 million shares, or 7.5% of ETHZilla, through entities linked to his Founders Fund.Originally a biotechnology company, 180 Life Sciences is shifting toward Ethereum-focused treasury management, software-enabled gaming, and entertainment, while seeking to monetize its legacy biotech assets.On Stocktwits, retail sentiment was ‘extremely bullish’ amid a 2,363% surge in 24-hour message volume.One user noted that traders who bought $ATNF warrants had seen outsized gains, attributing the rally largely to Ethereum’s strength and calling crypto treasury plays “hot” across multiple tickers.<stembedurl>https://stocktwits.com/CCTVon/message/624880257</stembedurl>Another user pointed out that $ATNF was now another Ethereum treasury company with backing from Peter Thiel, who had also invested in $BMNR, and said they planned to take a position.<stembedurl>https://stocktwits.com/moonstocks777/message/624875436</stembedurl>180 Life Sciences’ stock has risen nearly 463% so far in 2025.For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration of the ethereum cryptocurrency 'altcoin' sits arranged for a photograph on April 25, 2018 in London, England. (Photo by Jack Taylor/Getty Images)

This Small-Cap Life Sciences Stock More Than Tripled, Thanks To An Ethereum Pivot And Peter Thiel

180 Life Sciences, set to rebrand as ETHZilla, revealed a $349 million Ethereum reserve, a staking plan with Electric Capital, and a 7.5% stake from Peter Thiel’s Founders Fund.

Equity

180 Life Sciences (ATNF) 180 Life Sciences surged more than 500% on Wednesday becoming the top gainer across U.S. exchanges, boosting retail sentiment.The <a href="https://stocktwits.com/news-articles/markets/equity/atnf-stock-surges-on-online-gaming-pivot/cJcz40JRIG">sharp rally</a> followed the company’s announcement of its strategic pivot into online gaming, or iGaming, a move that seems to have sent retail investors into a frenzy.Retail sentiment on Stocktwits has skyrocketed to ‘extremely bullish’ (97/100) from ‘neutral’ a day ago.<img src="https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/Screenshot_2024_10_16_223155_cd82ae123f.png" alt="Screenshot 2024-10-16 223155.png">NuScale Power Corp. (SMR)NuScale Power shares surged 33% on Wednesday, buoyed by <a href="https://stocktwits.com/news-articles/markets/equity/amazon-signs-agreements-to-support-nuclear-energy-development/cJcza0dRIc">Amazon's decision</a> to invest in nuclear energy to power its data centers and other facilities at its Washington state headquarters.NuScale specializes in small modular reactors (SMRs), the same cutting-edge technology Amazon is considering to meet its growing energy demands. The stock soared to an all-time high of $18.01, marking a remarkable 473% year-to-date increase.Retail sentiment on Stocktwits has dramatically shifted, moving from 'bearish' to 'extremely bullish' (97/100) within a day.<img src="https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/Screenshot_2024_10_16_225310_41cad3a0dc.png" alt="Screenshot 2024-10-16 225310.png">Korro Bio (KRRO)Korro Bio's shares skyrocketed 111% on Wednesday following Wave Life Sciences’ <a href="https://stocktwits.com/news-articles/markets/equity/wave-life-sciences-stock-surges-on-rna-editing-breakthrough/cJczOOPRI5">announcement</a> of early validation for its latest RNA editing technology, a promising breakthrough in the field of genetic medicine.Korro Bio is heavily investing in RNA editing therapies, specifically targeting Alpha-1 Antitrypsin Deficiency (AATD). The company plans to seek regulatory approval by the end of the year to begin clinical trials for its RNA editing treatments.Retail sentiment around the company on Stocktwits has been initiated at ‘extremely bullish’ (97/100).<img src="https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/Screenshot_2024_10_16_231152_5247ea7ca2.png" alt="Screenshot 2024-10-16 231152.png">For updates and corrections email newsroom@stocktwits.com.Read more:<a href="https://stocktwits.com/news-articles/markets/equity/tsla-stock-falls-after-robotaxi-event-underwhelms/cJcVcLcR4T">&nbsp;</a><a href="https://stocktwits.com/news-articles/markets/equity/abbott-labs-stock-dips-pre-market-on-narrowed-profit-outlook-retail-turns-bearish/cJcz2u7R4D">Abbott Labs Stock Dips Pre-Market On Narrowed Profit Outlook: Retail Turns Bearish</a>

Rising stock prices of 180 Life Sciences, Korro Bio, and NuScale Power fuel bullish retail sentiment on Stocktwits

180 Life Sciences, Korro Bio, NuScale Power: Retail Investors Turn Most Bullish On These Stocks

Small-cap stocks like Korro Bio and NuScale Power are benefiting from the momentum generated by larger stocks.

Shares of 180 Life Sciences Corp. (<a class="mention" data-mention="$ATNF" data-symbol-id="ATNF" href="https://stocktwits.com/symbol/ATNF" target="_blank">$ATNF</a>) surged more than 500% on Wednesday, becoming the top gainer across U.S. exchanges, boosting retail sentiment.The sharp rally followed the company’s announcement of its strategic pivot into online gaming, or iGaming, a move that has sent retail investors into a frenzy.In a letter to shareholders, interim CEO Blair Jordan revealed that 180 Life Sciences plans to enter the global iGaming market using a newly acquired blockchain-based gaming platform, which supports cryptocurrency transactions.Initially, the company will focus on B2C online casinos, with plans to expand into a B2B model that will provide blockchain-enabled technology solutions to gaming operators worldwide.180 Life highlighted that it sees attractive acquisition opportunities within the iGaming industry, leveraging the company’s Nasdaq listing to consolidate private gaming firms.“We hope that this liquidity advantage will allow 180 to acquire private gaming companies at attractive valuations,” the company stated, though no immediate acquisitions are planned as it continues conducting preliminary diligence.<figure class="image"><a href="https://stocktwits.com/symbol/ATNF"><img style="aspect-ratio:1314/320;" src="https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/ATNF_sentiment_and_message_volume_Oct_16_2024_910b66e22e.png" alt="ATNF sentiment and message volume Oct 16 2024.png" width="1314" height="320"></a><figcaption>ATNF sentiment and message volume Oct 16 2024 as of 10:45 am ET | source: Stocktwits</figcaption></figure>Retail investors responded enthusiastically on Stocktwits, where sentiment shifted to ‘extremely bullish’ (97/100) from ‘neutral’ just a day prior.<stembedurl>https://stocktwits.com/JJ353/message/589101640</stembedurl><stembedurl>https://stocktwits.com/evanevans/message/589087909</stembedurl>180 Life Sciences confirmed last week that it had regained compliance with Nasdaq’s minimum stockholders’ equity requirement, a crucial step that enables it to focus on its iGaming expansion while continuing to advance its biotechnology programs.Earlier this month, the company reported progress on its synthetic CBD analogs (SCAs), designed as safer, more effective alternatives to unregulated CBD products.Year-to-date, the stock is up more than 165%. The company's current market cap is under a million dollars.Read next: <a href="https://stocktwits.com/news-articles/markets/equity/nvax-stock-falls-after-fda-clinical-hold-on-vaccine-candidates/cJczdHnR4y">Novavax Stock Tanks After FDA’s Clinical Hold On Vaccine Candidates: Retail Turns Jittery</a> &nbsp;

These stocks hit a new 52-week high today

180 Life Sciences Turns Retail Heads With Online Gaming Entry, Stock Surges 500% 

Interim CEO Blair Jordan revealed that 180 Life Sciences plans to enter the global iGaming market using a newly acquired blockchain-based gaming platform, which supports cryptocurrency transactions.

ETHZilla Corp. is a technology company in the decentralized finance (DeFi) industry, which intends to connect financial institutions, businesses, and organizations worldwide by enabling secure, accessible blockchain transactions through Ethereum Network protocol implementations. It continues to maintain the deployment and development of its biotech and gaming operations. The company was founded by Marc Feldmann, Lawrence J. Steinman, and Jonathan B. Rothbard on September 7, 2016 and is headquartered in Palm Beach, FL.

ETHZilla Corp

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