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ImmunityBio, Inc. is a clinical stage immunotherapy company. It develops next generation therapies that drive immunogenic mechanisms for defeating cancers and infectious diseases. The company's immunotherapy platform activates both the innate and adaptive immune systems to create long term immunological memory. ImmunityBio was founded by Patrick Soon-Shiong in 2014 and is headquartered in San Diego, CA.

ImmunityBio Inc

ImmunityBio's new 3-year clinical roadmap detailing ANKTIVA's expansion across numerous cancer types, sepsis, and lymphopenia, alongside impressive revenue growth, is fueling robust community discussion and short squeeze speculation, as the company is seen transforming beyond a single-drug focus.

Paramount Skydance Corp. is a next-generation global media and entertainment company that engages in providing content creation and distribution services. It operates through the following business segments: Studios, Direct-to-Consumer, and TV Media. Its portfolio unites brands including Paramount Pictures, Paramount Television, CBS, CBS News, Nickelodeon, MTV, BET, Comedy Central, Showtime, Paramount Plus, Pluto TV, and Skydance’s Animation, Film, Television, Interactive/Games, and Sports divisions. The company was founded on June 3, 2024 and is headquartered in New York, NY.

Paramount Skydance Corp. - Ordinary Shares - Class B

Paramount Skydance is trending as its enhanced offer for Warner Bros. Discovery, including financial protections and a ticking fee, has prompted WBD to re-engage in deal discussions. The community is actively debating PSKY's perceived clearer regulatory path compared to Netflix's ongoing antitrust scrutiny, while also weighing the potential debt implications for PSKY if the acquisition proceeds.

International Business Machines Corp. is an information technology company, which engages in the provision of integrated solutions that leverage information technology and knowledge of business processes. It operates through the following segments: Software, Consulting, Infrastructure, Financing, and Other. The Software segment combines hybrid cloud platform and software solutions to help clients become more data-driven, and to automate, secure, and modernize their environments. The Consulting segment focuses on integrating skills on strategy, experience, technology and operations by domain and industry. The Infrastructure segment offers solutions for hybrid cloud and is the foundation of the hybrid cloud stack. Infrastructure is optimized for infusing AI into mission-critical transactions and tightly integrated with IBM Software including Red Hat for accelerated hybrid cloud benefits. The Financing segment refers to the client and commercial financing, facilitating IBM clients’ acquisition of IT systems, software, and services. The company was founded by Charles Ranlett Flint and Thomas J. Watson Sr. on June 16, 1911 and is headquartered in Armonk, NY.

International Business Machines Corp.

IBM is trending sharply lower as fears escalate that Anthropic's Claude AI tool could disrupt its legacy COBOL modernization services, despite community discussions highlighting IBM's established AI integrations and robust fundamentals.

Atlassian Corp. is a holding company, which engages in providing team collaboration and productivity software. Its products include Jira Software, Confluence, Jira Service Management, and Loom. The company was founded by Michael Cannon-Brookes and Scott Farquhar in October 2002 and is headquartered in San Francisco, CA.

Atlassian Corporation - Ordinary Shares - Class A

Atlassian Corporation Plc

Atlassian is trending due to a significant post-earnings sell-off, despite reporting strong results, driven by pervasive market fears that AI tools like Claude will disrupt and replace traditional SaaS platforms. This has led to widespread panic among investors over substantial losses, though some believe the stock is now deeply oversold and fundamentally undervalued.

BlackRock Institutional Trust Company N.A. - iShares Expanded Tech-Software Sector ETF

iShares Expanded Tech-Software Sector ETF

The iShares Expanded Tech-Software Sector ETF ($IGV) is trending as widespread fears of AI disruption, particularly from Anthropic's Claude and recent research, are driving a dramatic "SaaS-pocalypse" sell-off across the software sector, though many argue the market's reaction is an extreme overreaction and a significant buying opportunity.

Ardelyx, Inc. is a biopharmaceutical company, which engages in the business of developing and commercializing biopharmaceutical products. The firm is also involved in developing a unique and innovative platform that enables the discovery of new biological mechanisms and pathways to develop potent and efficacious therapies that minimize the side effects and drug-drug interactions frequently encountered with traditional, systemically absorbed medicines. The company was founded by Dominique Charmot, Peter G. Schultz, and Jean M. Frechet in October 2007 and is headquartered in Waltham, MA.

Ardelyx Inc

Ardelyx (ARDX) is trending amid debate following mixed Q4 results, where robust Ibsrela revenue growth and extended patent life are weighed against increased operating expenses that temper near-term profitability expectations. The community is split between those viewing the stock as deeply undervalued with strong long-term potential and ongoing buyout speculation, and those cautious about immediate financial performance and market volatility.

Vir Biotechnology, Inc. operates as a clinical-stage immunology company that focuses on combining immunologic insights with cutting-edge technologies to treat and prevent serious infectious diseases. The firm's technology platforms include antibody, T cell, innate immunity and siRNA, which are designed to stimulate and enhance the immune system by exploiting critical observations of natural immune processes. The company was founded by Robert Taylor Nelsen, Klaus Frueh, Jay Parrish, Lawrence Corey, and Louis Picker in April 7, 2016 and is headquartered in San Francisco, CA.

Vir Biotechnology Inc

Vir Biotechnology is trending due to a global strategic collaboration with Astellas for its prostate cancer T-cell engager, VIR-5500, backed by promising updated Phase 1 data. The community is actively discussing the potential for a significant run, with some anticipating a short squeeze, while others remain cautious, expecting a historical pullback.

The Home Depot, Inc. engages in the sale of building materials and home improvement products. Its products include building materials, home improvement products, lawn and garden products and decor products. The firm operates through the following geographical segments: U.S., Canada and Mexico. It offers home improvement installation services, and tool and rental equipment. The company was founded by Bernard Marcus, Arthur M. Blank, Kenneth Gerald Langone and Pat Farrah on June 29, 1978 and is headquartered at Atlanta, GA.

Home Depot, Inc.

Home Depot is trending after its Q3 earnings miss, lowered full-year outlook, and cautious 2026 guidance, with the community actively debating the impact of softening housing demand and consumer spending, further fueled by the company's explanation citing a "lack of storms" for sales underperformance.

Visa, Inc. engages in the provision of digital payment services. It also facilitates global commerce through the transfer of value and information among a global network of consumers, merchants, financial institutions, businesses, strategic partners, and government entities. It offers debit cards, credit cards, prepaid products, commercial payment solutions, and global automated teller machines. The company was founded by Dee Hock in 1958 and is headquartered in San Francisco, CA.

Visa Inc - Ordinary Shares - Class A

Visa Inc

Visa is trending due to recent regulatory challenges, including a blocked acquisition in Mexico and political proposals for credit card interest rate caps, sparking debate among investors who are weighing these pressures against the company's strong fundamentals and evolving role in AI and stablecoin payments.

Zeta Global Holdings Corp. operates as a marketing technology software company, which engages in the provision of enterprises with consumer intelligence and marketing automation software. It enables its customers to target, connect and engage consumers through software that delivers marketing across all addressable channels, including email, social media, web chat, connected TV and video among others. The company was founded by David A. Steinberg and John Sculley on May 9, 2012 and is headquartered in New York, NY.

Zeta Global Holdings Corp - Ordinary Shares - Class A

Zeta Global Holdings Corp

ZETA is actively debated amid a deep sector-wide software sell-off, fueled by "AI replacement" fears, causing many investors to view current price drops as an opportune "discount" to accumulate shares before its anticipated strong earnings report.

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Shares of Swiss pharmaceutical giant Novartis AG were flat on Friday morning in heavy trading volume, despite the company reporting impressive quarterly results.&nbsp;Novartis posted core fourth-quarter (Q4) earnings per share (EPS) of $1.98, up from $1.53 last year, beating the consensus estimate of $1.80.&nbsp;Meanwhile, Q4 revenue reached $13.2 billion, surpassing the previous year’s $11.4 billion and analysts’ expectations of $12.84 billion.The company attributed its strong sales growth to its blockbuster heart-failure drug Entresto and arthritis medication Cosentyx.&nbsp;CEO Vas Narasimhan expressed optimism, stating, “In our first full year as a pure-play innovative medicines company, Novartis delivered one of the strongest financial performances in our history, growing sales 12% cc [constant currency basis] and core operating income 22% cc.”&nbsp;He added that the company achieved key innovation milestones, including new drug approvals and promising data that would drive growth in the mid- to long-term.Despite the upbeat results, retail sentiment on Stocktwits was mixed. Although message volume surged into ‘extremely bullish’ territory, sentiment remained ‘bearish,’ indicating some hesitation among retail traders.&nbsp;<figure class="image"><img style="aspect-ratio:1318/324;" src="https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/NVS_sentiment_and_message_volume_Jan_31_d92ad15174.png" alt="NVS sentiment and message volume Jan 31.png" width="1318" height="324"><figcaption>NVS sentiment and message volume Jan 31 as of 11:45 am ET | source: Stocktwits</figcaption></figure>Novartis is facing upcoming patent expirations for three key drugs, with Entresto expected to face generic competition in the U.S. mid-year.&nbsp;Additionally, two other top-selling drugs, Tasigna for leukemia and Promacta for a blood disorder, will face generics in the U.S.However, Narasimhan reassured investors, emphasizing the company’s “tremendous replacement power” and its ability to bring new treatments to market when patents on existing drugs expire.&nbsp;He also highlighted the company’s strong pipeline, with more than 30 assets that could drive differentiated growth over the long term, including updates on its cardiovascular drug candidate pelacarsen and a key late-stage trial this year.Looking ahead, Novartis forecasted FY25 net sales growth in the mid- to high-single-digit range, with core operating income expected to grow in the high single to low double-digit range.&nbsp;The company also proposed a 6.1% increase in its dividend to 3.50 Swiss francs per share for 2024.Although <a href="https://stocktwits.com/symbol/NVS">Novartis' stock</a> has lost 0.1% over the past 12 months, it is up more than 7% so far this year.For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, the Novartis company logo is seen displayed on a smartphone screen. (Photo Illustration by Piotr Swat/SOPA Images/LightRocket via Getty Images)

Novartis Gets Retail Chatting After Upbeat Q4, But Sentiment Stays Tepid Amid Volatile Trading

The company is facing upcoming patent expirations for three key drugs, with Entresto expected to face generic competition in the U.S. mid-year. 

Equity

The company is facing upcoming patent expirations for three key drugs, with Entresto expected to face generic competition in the U.S. mid-year. 


U.S. shares of Sony Group Corp. (<a class="mention" data-mention="$SONY" data-symbol-id="SONY" href="https://stocktwits.com/symbol/SONY" target="_blank">$SONY</a>) surged over 7% pre-market Friday after the company reported a 69% jump in fiscal&nbsp;second-quarter (Q2) profit, driven by strength in its gaming and imaging divisions.&nbsp;Sony posted a profit of 338.5 billion yen (about $2.21 billion) on revenue of 2.91 trillion yen, up 3% year-over-year.&nbsp;The&nbsp;earnings per share (EPS) of 55.86 yen beat the consensus estimate of 39.84 yen, according to FactSet.The company saw robust performance in its Game &amp; Network Services and Imaging &amp; Sensing Solutions segments.&nbsp;Operating profit for the imaging business nearly doubled to 92.41 billion yen due to strong demand for image sensors, though Sony lowered its full-year sales and profit outlook for this segment.&nbsp;Despite selling only 3.8 million PlayStation 5 units this quarter — down from 4.9 million a year ago — Sony raised its annual profit forecast for the game division to 355.0 billion yen from 320.0 billion yen.Sony also launched its upgraded PlayStation 5 Pro this week, ahead of the holiday season, offering enhanced performance over the original 2020 model.&nbsp;The company revised its revenue forecast for the fiscal year ending March 2025, now expecting a 2.4% decline to 12.71 trillion yen, slightly better than the previously forecasted 3.2% drop.&nbsp;However, it maintained its outlook for a modest 1% increase in net profit to 980.0 billion yen.On Stocktwits, Sony was one of the top 30 trending tickers as of 7:30 am ET, reflecting heightened retail interest.&nbsp;<stembedurl>https://stocktwits.com/DT777/message/591690734</stembedurl>Still, Sony’s U.S.-listed shares are down over 2% year-to-date. Meanwhile, Tokyo-listed shares of the firm ended 1.2% higher on Friday.For updates and corrections, email&nbsp;<a target="_blank" rel="noopener noreferrer nofollow" href="mailto:newsroom@stocktwits.com">newsroom@stocktwits.com</a>Read next:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/usm-tds-stocks-get-upgraded-by-raymond-james/cJ45RFrRaJ">Are USM, TDS Trump Trades Now? Raymond James Upgrades Mid-Cap Telecom Stocks On Reduced Regulatory Risk</a>

Sony also launched its upgraded PlayStation 5 Pro this week, ahead of the holiday season.

Sony Stock Jumps Pre-Market As Profit Booms Nearly 70%: Retail Buzz Builds

Despite selling only 3.8 million PlayStation 5 units this quarter — down from 4.9 million a year ago — Sony raised its annual profit forecast.

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