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RAGE GUY (RAGE) is a cryptocurrency inspired by the Rage Guy meme, one of the earliest and most recognizable characters from internet rage comics. The project captures the cultural legacy of early meme history and brings it onto the blockchain in tokenized form. It is designed as a community-driven digital asset that celebrates internet culture, nostalgia, and the role memes play in shaping online communities.

Rage Guy

Rage Crypto is trending as its community leans into the project's roots as an internet culture OG, actively promoting their restored original comic-making tools to generate viral, cross-platform engagement. Supporters are focused on aggressive grassroots 'bagworking' and building a dedicated following, framing the project as a highly undervalued play on historical meme nostalgia.

"What's Updog?" is a Community Led token.

UpDog

UpDog is trending as the community highlights its multi-year track record and organic growth on the Solana network while actively encouraging others to load their bags. Participants are rallying behind the ticker with memes and dad jokes, emphasizing the project's presence on the Jupiter strict list as a core point of interest.

OpenGradient is the Network for Open Intelligence — a decentralized infrastructure network designed to host, inference, and verify AI models at scale. Rather than functioning as a standalone blockchain, OpenGradient operates as a specialized AI coprocessor: it enables applications, blockchains, and autonomous agents to outsource computationally-heavy AI tasks to a dedicated network of GPU and Trusted Execution Environment (TEE) nodes. The validator set verifies every computational proof (TEE attestation or zkML proof) at the consensus level before it is committed on-chain, enabling trustless usage of AI from any network or application.

OpenGradient

OpenGradient is gaining momentum as a newly listed token benefiting from increased trading volume and heightened public awareness. Investors are actively discussing the asset's growth potential while comparing it to other high-volatility projects following recent exchange launches.

Aerodrome Finance is a next-generation AMM designed to serve as Base's central liquidity hub, combining a powerful liquidity incentive engine, vote-lock governance model, and friendly user experience. Aerodrome inherits the latest features from Velodrome V2.

Aerodrome Finance

Aerodrome Finance is attracting significant community attention as investors debate its role as a key liquidity hub on the Base ecosystem, with many closely tracking its ongoing revenue generation and supply-reduction efforts. While some discuss the potential for long-term growth driven by institutional interest and upcoming network expansions, others are navigating recent price volatility and debating the merits of accumulation at current levels.

ETHGas is a Blockspace Infrastructure protocol that decomposes Ethereum blockspace into tradable, composable block units, enabling real‑time block production and laying the foundation for a crypto‑native commodities market for gas. By restructuring gas as a financial primitive, ETHGas unlocks: - Faster block times (sub‑second confirmations vs 12‑second Ethereum blocks) through real‑time sequencing. - A futures/forward market for gas, enabling the creation of a native Ethereum yield curve. - Gas abstraction for end users via the Open Gas Initiative, removing gas volatility and shifting costs to protocols. - Commoditization of blockspace, similar to energy or metals markets in traditional finance.

ETHGas

GWEI is gaining momentum through exchange listings and community buzz surrounding its utility in Ethereum gas fee dynamics, despite relatively quiet social media engagement. Traders are actively monitoring its price action in relation to broader Ethereum network activity and staking rewards.

The TROLL token on the Solana network is a meme coin inspired by internet trolling culture, designed for entertainment and community engagement with no intrinsic value. Built on Solana’s blockchain, it leverages the network’s fast transactions and low fees to appeal to meme enthusiasts. Launched on decentralized exchanges, TROLL aims to foster a fun, community-driven ecosystem through social media, influencer partnerships, and viral marketing, embodying the playful spirit of online trolling.

Troll

The $TROLL community is heavily promoting the coin as a classic memetic powerhouse, drawing comparisons to other high-profile internet culture tokens. Investors are actively discussing the project's roots in viral Rage Comics while pushing for broader market adoption through community-driven content and social media awareness.

Dumb SEND IT

Dumb SEND IT ($DSIT) is gaining traction as investors flock to the newly launched, low-cap meme coin, with the community actively rallying to drive growth through social media engagement and trending efforts. Supporters are focused on the developer's commitment to transparency and periodic airdrops as they work to overcome early liquidity hurdles and build momentum on Solana-based platforms.

The Aircoin memecoin was born from a viral Twitter post from March, 2014 which proclaimed the following:   Evolution: 1. Aircoin 2. Fartcoin 3. Artcoin  Aircoin was launched in August, 2025 and CTO'd twice, with the second CTO team bringing vast experience and expertise to the project. The team includes industry veterans and visual arts professionals.  Aircoin is destined for greatness as a premier memecoin on the BONK.fun platform.

aircoin

$AIRCOIN is gaining attention on Solana due to its long-term community conviction, characterized by high token lock rates and significant holder retention. Investors are highlighting the project's consistent development and treasury growth as a differentiator from typical short-lived memecoin trends.

Orca is the most user-friendly DEX on Solana.  Orca is one of the first general-purpose AMMs launched on Solana. Users can swap assets, provide liquidity, and earn yield through an easy-to-use interface. Projects can use Orca as a money-lego to easily integrate swapping, farming, or on-chain data into their dApp.  Orca strives to provide easy and effective financial tools for everyone, bringing DeFi to the masses.

Orca

Orca is seeing massive buying momentum and volatility as traders discuss a potential short squeeze fueled by high short interest and market anticipation of upcoming DAO-led buyback programs. The community is actively debating the token's low circulating supply as a catalyst for potential upside while keeping a close watch on key technical levels.

PENGU is the official coin of Pudgy Penguins.  Pudgy Penguins has become the face of crypto with one of the most influential communities in the industry. From large companies wearing the Penguin, to being featured in ETF commercials, to garnering millions of followers and over 100 billion views, the Pengu has become a cultural icon making PENGU the world’s social currency.  PENGU allows for the ever-expanding Pudgy Penguin fanbase and the hundreds of millions of people outside of crypto that see and share the Pudgy Penguin everyday, to join The Huddle. PENGU is a symbol for community, memes, and good vibes.  Believe in Pengu. Believe in the Prophecy.

Pudgy Penguins

Pudgy Penguins is trending as holders discuss its transition from a niche digital asset to a phygital powerhouse, fueled by its growing retail presence in major physical stores and utility-focused developments. The community remains focused on long-term accumulation, debating the potential for future price breakthroughs while drawing comparisons to established meme coins.

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<ul class="summary-bullets"><li>The trial was conducted by &nbsp;Sagimet’s license partner for China, Ascletis Bioscience Co., in 480 patients with moderate to severe acne vulgaris.</li><li>The company said that once daily oral 50 mg Denifanstat achieved highly statistically significant and clinically meaningful improvements across all primary and secondary efficacy endpoints in the study.&nbsp;</li><li>Ascletic said in October that it plans to submit a new drug application to China National Medical Products Administration for Denifanstat for the treatment of moderate-to-severe acne soon. &nbsp;</li></ul>Shares of Sagimet Biosciences Inc. (SGMT) soared 22% by Friday afternoon after its Denifanstat drug yielded positive results in the treatment of acne in a late-stage trial.The trial was conducted by Sagimet’s license partner for China, Ascletis Bioscience Co., in 480 patients with moderate to severe acne vulgaris. It was aimed at evaluating the safety and efficacy of Denifanstat in acne treatment.<h2 class="st-heading-2">Trial Takeaways</h2>Acne vulgaris is a common skin condition caused by clogged hair follicles from oil and dead skin cells, which can result in whiteheads, blackheads, pimples, and in severe cases, painful nodules and cysts.The company <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://ir.sagimet.com/news-releases/news-release-details/denifanstat-achieved-all-endpoints-treatment-moderate-severe">said</a> that once daily oral 50 mg Denifanstat achieved highly statistically significant and clinically meaningful improvements across all primary and secondary efficacy endpoints. Primary endpoints included the percentage change in total lesion count, and the percentage change in inflammatory lesion count, among others.At week 12, treatment success rates with Denifanstat were more than double those of placebo, with marked reductions in both inflammatory and non-inflammatory lesions, it noted.Furthermore, the drug was generally well-tolerated, the company added.<h2 class="st-heading-2">Plans Ahead</h2>Ascletis said in October that it plans to soon submit a new drug application to China National Medical Products Administration for Denifanstat for the treatment of moderate-to-severe acne.Sagimet, meanwhile, is studying the drug in the treatment of metabolic dysfunction associated steatohepatitis, a serious form of liver disease, characterized by fat buildup, inflammation, and liver cell damage.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>On Stocktwits, retail sentiment around<a href="https://stocktwits.com/symbol/SGMT"> SGMT stock</a> jumped from ‘bearish’ to ‘bullish’ territory over the past 24 hours, while message volume increased from ‘normal’ to ‘extremely high’ levels.<figure class="image"><img style="aspect-ratio:622/59;" src="data:image/png;base64,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" width="622" height="59" alt="SGMT's Sentiment Meter and Message Volume as of 2:15 p.m. ET on Oct. 24, 2025 | Source: Stocktwits"><figcaption>SGMT's Sentiment Meter and Message Volume as of 2:15 p.m. ET on Oct. 24, 2025 | Source: Stocktwits</figcaption></figure>A Stocktwits user sounded positive on the stock, citing the size of the Chinese market.<stembedurl>https://stocktwits.com/Mikrus36/message/633613843</stembedurl>SGMT stock has nearly doubled this year.&nbsp;Read also: <a href="https://stocktwits.com/news-articles/markets/equity/gm-reportedly-lays-off-over-200-employees-days-after-raising-2025-earnings-guidance/cLGJFcKR3tb">GM Reportedly Lays Off Over 200 Employees Days After Raising 2025 Earnings Guidance</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

Rising stock market chart on a trading board background.

Sagimet Biosciences Stock Soars After Positive Data For Experimental Drug In Acne Study

The trial was conducted by  Sagimet’s license partner for China, Ascletis Bioscience Co., in 480 patients with moderate to severe acne vulgaris.

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