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Candel Therapeutics, Inc. is a clinical stage biotechnology company, which engages in the development and commercialization of viral immunotherapies. Its pipeline includes CAN-2409 and CAN-3110. The company was founded by Estuardo Aguilar-Cordova in 2002 and is headquartered in Needham, MA.

Candel Therapeutics Inc

Candel Therapeutics is trending after announcing a public stock offering alongside a non-dilutive royalty funding agreement for its prostate cancer therapy, CAN-2409; the community is actively debating whether this represents a strategic capital raise for commercialization and pipeline advancement or a significant dilution impacting shareholder value.

GRAIL, Inc. operates as a commercial-stage healthcare company, which engages in the development of a technology for early detection of cancer. It utilizes machine learning, software, and automation to detect and identify multiple deadly cancer types in earlier stages. The company was founded by Jeffrey T. Huber, William H. Rastetter, Mostafa Ronaghi, and Richard D. Klausner on September 11, 2015 and is headquartered in Menlo Park, CA.

GRAIL Inc.

GRAIL (GRAL) is experiencing a sharp decline following mixed trial results for its Galleri cancer test in a UK study that missed a primary endpoint, with bears predicting further collapse. However, many in the community view this as an overreaction, citing strong underlying data for early cancer detection, substantial cash reserves, an ongoing US FDA submission, and recent institutional investments at higher valuations.

Ardelyx, Inc. is a biopharmaceutical company, which engages in the business of developing and commercializing biopharmaceutical products. The firm is also involved in developing a unique and innovative platform that enables the discovery of new biological mechanisms and pathways to develop potent and efficacious therapies that minimize the side effects and drug-drug interactions frequently encountered with traditional, systemically absorbed medicines. The company was founded by Dominique Charmot, Peter G. Schultz, and Jean M. Frechet in October 2007 and is headquartered in Waltham, MA.

Ardelyx Inc

Ardelyx is trending after its Q4 earnings, which showed strong revenue growth but an EPS miss, as the company prioritizes significant investments in pipeline expansion, including a new patent extending protection to 2042 and dosing the first patient in a Phase 3 CIC trial. Investors are debating the short-term impact of increased expenses versus the long-term value from a potential buyout and rising analyst price targets, despite general market volatility.

StarkNet is a permissionless decentralized Layer 2 (L2) validity rollup, built to allow Ethereum to scale via cryptographic protocols called STARKs, without compromising Ethereum’s core principles of decentralization, transparency, inclusivity and security. The StarkNet Token is needed to operate the ecosystem, maintain and secure it, decide on its values and strategic goals, and direct its evolution. This token will be required for (i) governance, (ii) payment of transaction fees on StarkNet, and (iii) participation in StarkNet’s consensus mechanism.

Starknet

Starknet is trending due to significant technological advancements like its quantum-resistant ZK-STARKs and new enterprise privacy integrations, alongside growing on-chain metrics such as rising TVL and developer activity, which the community sees as a strong opportunity despite past token unlock FUD.

Codatta

Codatta (XNY CRYPTO) is trending as it demonstrates significant strength and outperformance amidst broader market fluctuations, leading the community to aggressively buy dips and anticipate further upward movement. Discussions highlight its underlying utility in decentralized AI and data.

Scilex Holding Co. engages in the acquisition, development, and commercialization of non-opioid pain management products for the treatment of acute and chronic pain. Its products include ZTLido, Elyxyb, and Gloperba. The company was founded on February 21, 2020 and is headquartered in Palo Alto, CA.

Scilex Holding Company

Scilex Holding Company is trending as investors debate the impact of its strategic $20 million investment in Quantum Scan Holdings and continued sales of Datavault AI shares, while community chatter focuses on CEO Henry Ji's controversial leadership, recent dividend revocation, and the company's precarious financial position.

Klarna Group Plc is a global digital bank and flexible payments provider. It operates through an AI-powered payments and commerce network that empowers people to pay smarter, with a mission to be available everywhere, for everything. The company was founded by Gustav Erik Niklas Adalberth, Karl Anders Victor Jacobsson, and Sebastian Marcin Siemiatkowski in 2005 and is headquartered in London, the United Kingdom.

Klarna Group plc

Klarna is trending sharply lower following a reported Q4 loss and cautious Q1 forecast, largely impacted by increased credit loss provisions. The community is actively debating the long-term viability of its Buy Now, Pay Later model and its path to profitability, with some viewing the significant price drop as an overreaction.

Walmart, Inc. engages in the retail and wholesale business. The company offers an assortment of merchandise and services at everyday low prices. It operates through the following business segments: Walmart U.S., Walmart International, and Sam's Club. The Walmart U.S. segment operates as a mass merchandiser of consumer products, operating under the Walmart and Walmart Neighborhood Market brands, including walmart.com. The Walmart International segment includes operations of wholly-owned subsidiaries in Canada, Chile, China, and Africa, and majority-owned subsidiaries in India, as well as Mexico and Central America. The Sam's Club segment manages membership-only warehouse clubs and operates samsclub.com. The company was founded by Samuel Moore Walton and James Lawrence Walton on July 2, 1962 and is headquartered in Bentonville, AR.

Walmart Inc

Walmart is a major talking point after its earnings report showcased robust e-commerce and advertising growth alongside a substantial share buyback, even as conservative full-year guidance fuels community debate over its high valuation and the outlook for consumer spending.

Solana is a high-performance Layer 1 blockchain designed for mass adoption by providing a fast, secure, and low-cost environment for decentralized applications. It distinguishes itself by scaling globally without the use of complex sharding or multiple layers, instead maintaining a single, unified ledger to avoid liquidity fragmentation. This architecture allows it to process thousands of transactions per second with sub-second finality, often at a cost of less than a penny per transaction.  The network operates on a unique hybrid model that combines Proof of Stake with an innovation called Proof of History, which functions as a decentralized clock to timestamp transactions. This system reduces the need for constant node communication, allowing the Sealevel engine to run non-conflicting smart contracts in parallel across multiple CPU cores. Further efficiency is gained through the Gulf Stream protocol, which reduces confirmation times by forwarding transactions to validators before the current block is finished.  Founded in 2017 by Anatoly Yakovenko, Solana is now supported by the Switzerland-based Solana Foundation and significant institutional investors like Andreessen Horowitz and Polychain Capital. The platform’s native token, SOL, serves as the primary currency for paying transaction fees, participating in network governance, and securing the system through staking.   Solana has also seen significant institutional adoption ranging from spot Solana ETFs to major partnerships including Visa's 2025 launch of USDC settlement on the network and the tokenization of public equity by firms like Galaxy Digital.

Solana

Solana is generating buzz as institutional interest grows through new staking loan structures and spot ETF inflows, with its ecosystem expanding into decentralized identity, gaming, and publishing. The community is actively debating its utility-driven growth, potential market decoupling, and the impact of upcoming regulatory clarity like the Clarity Act.

Moonlake Immunotherapeutics operates as a clinical-stage biotechnology company. It offers tri-specific Nanobody, Sonelokimab to address significant unmet needs in inflammatory skin and joint diseases. The company was founded by Kristian Reich, Jorge Santos da Silva, and Arnout Ploos van Amstel in 2021 and is headquartered in Zug, Switzerland.

MoonLake Immunotherapeutics - Ordinary Shares - Class A

MoonLake Immunotherapeutics

MoonLake Immunotherapeutics is trending with high anticipation for its upcoming Investor Day, where new data on its best-in-class sonelokimab nanobody is expected, driving community excitement amidst significant institutional share repurchases and speculation about a potential short squeeze from its current undervaluation.

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