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Iovance Biotherapeutics, Inc. engages in the development and commercialization of cell therapies using autologous tumor-infiltrating lymphocytes (TIL) for the treatment of cancer. Its products include Amtagvi (lifileucel), and Proleukin (aldesleukin). The firm also develops investigational TIL therapies for other solid tumor cancers. The company was founded by Robert T. Brooke on September 17, 2007 and is headquartered in San Carlos, CA.

Iovance Biotherapeutics Inc

Updated Phase 2 lung-cancer data triggered a sharp selloff: lifileucels overall response rate was 24.6%, while a small biomarker-selected subgroup showed a higher rate of 59.1%. Traders are divided between viewing the subgroup results as a promising path for precision treatment and worrying that the narrower population, need for further validation, and potentially longer route to approval weaken the opportunity.

Alphabet, Inc. is a holding company, which engages in software, health care, transportation, and other technologies. It operates through the following segments: Google Services, Google Cloud, and Other Bets. The Google Services segment includes products and services, such as ads, Android, Chrome, devices, Google Maps, Google Play, Search, and YouTube. The Google Cloud segment refers to infrastructure and platform services, collaboration tools, and other services for enterprise customers. The Other Bets segment relates to the sale of healthcare-related services and internet services. The company was founded by Lawrence E. Page and Sergey Mikhaylovich Brin on October 2, 2015 and is headquartered in Mountain View, CA.

Alphabet Inc - Ordinary Shares - Class A

Alphabet Inc Class A

Alphabets earnings miss and sharp selloff are drawing attention, with slower Search and advertising growth, heavy AI infrastructure spending, and negative free cash flow fueling concerns about monetization and returns. Many traders call the drop an overreaction and are buying the dip on Cloud and AI optimism, while others see lasting pressure from AI competition and weaker Search economics.

ServiceNow, Inc. engages in the provision of an end-to-end workflow automation platform for digital businesses. Its Now Platform is a cloud-based solution embedded with artificial intelligence (AI) and machine learning (ML). The company was founded by Frederic B. Luddy in June 2004 and is headquartered in Santa Clara, CA.

ServiceNow Inc

ServiceNows quarterly results and softer outlook for near-term contracted revenue growth triggered a sharp selloff, despite revenue growth and stronger AI targets. Traders are split between calling the move an overreaction and arguing that slowing contract growth, high expectations, and uncertainty over AIs impact on software justify the repricing.

Alphabet Inc - Ordinary Shares - Class C

Alphabets earnings miss has triggered a sharp selloff, with traders focused on slower Search and advertising growth and heavy AI infrastructure spending weighing on cash flow. Some see the decline as an overreaction given strong Cloud growth and are buying the dip, while others question whether AI investments can generate returns and whether AI is eroding Google Searchs business.

Microsoft Corp. engages in the development and support of software, services, devices, and solutions. It operates through the following segments: Productivity and Business Processes, Intelligent Cloud, and More Personal Computing. The Productivity and Business Processes segment is composed of products and services relating to productivity, communication, and information services such as Office Commercial, Office Consumer, LinkedIn, and Dynamics business solutions. The Intelligent Cloud segment consists of public, private, and hybrid server products and cloud services for businesses and developers, as well as enterprise and partner services. The More Personal Computing segment refers to products and services including Windows operating system, Windows cloud services, Surface, HoloLens, personal computer accessories, Xbox hardware, Xbox Cloud Gaming, Microsoft News, and Microsoft Edge. The company was founded by Paul Gardner Allen and William Henry Gates, III in 1975 and is headquartered in Redmond, WA.

Microsoft Corporation

Microsoft Corp

Microsofts quarterly earnings beat and accelerating Azure growth, with stronger cloud guidance, drew attention, but shares faded after the initial rally. Traders debated whether AI infrastructure spending, weaker free cash flow and a new bond offering weighed on the stock, while others argued strong cloud demand supports the investment; some also blamed broader tech weakness following Alphabets results.

Norwegian Cruise Line Holdings Ltd. engages in the provision of cruise travel services. It offers cruise experiences for travelers with itineraries in Europe, Asia, Australia, New Zealand, South America, Africa, Canada, Bermuda, Caribbean, Alaska and Hawaii. Its brands include Norwegian Cruise Line, Oceania Cruises, and Regent Seven Seas Cruises. The company was founded in 1966 and is headquartered in Miami, FL.

Norwegian Cruise Line Holdings Ltd

Norwegians quarterly earnings beat expectations and its raised full-year outlook are driving a sharp rally. Many traders are celebrating the results and speculating about short covering, while others are taking profits and flagging debt, fuel costs, and lingering yield concerns.

Teladoc Health, Inc. engages in the provision of telehealthcare services using a technology platform via mobile devices, the Internet, video and phone. It operates through the following segments: Teladoc Health Integrated Care, BetterHelp, and Others. The Teladoc Health Integrated Care segment offers virtual medical services. The BetterHelp segment includes virtual mental health and other wellness services. The company was founded in June 2002 by George Byron Brooks, Michael Gorton, and Gary Wald and is headquartered in New York, NY.

Teladoc Health Inc

Teladocs quarterly results and outlook are driving the rally, with traders highlighting improved profitability, margins and cash generation alongside stronger EBITDA guidance. Bulls see signs of a turnaround and speculate about a short squeeze, while skeptics point to declining revenue and ongoing BetterHelp weakness.

Hyperliquid Strategies, Inc. is a holding and operating company, which engages in the business of crypto asset management. The firm operates as a digital asset treasury company which focuses on the Hyperliquid ecosystem. The company was founded on July 2, 2025 and is headquartered in New York, NY.

Hyperliquid Strategies Inc.

PURR is drawing attention as traders connect its move to strength in Hyperliquids HYPE token, with some expecting the digital-asset treasury stock to catch up and speculating about short covering. Others argue that potential share dilution and PURRs lagging performance versus HYPE could limit gains.

Carvana Co. is a holding company and an eCommerce platform, which engages in the buying and selling of used cars. The company was founded by Ernest Garcia, III, Benjamin Huston and Ryan Keeton in 2012 and is headquartered in Tempe, AZ.

Carvana Co. - Ordinary Shares - Class A

Carvana Co.

Carvanas Q3 results are driving attention, with record vehicle sales and revenue growth lifting shares despite an earnings-per-share miss. Traders are divided between those welcoming the sales momentum and outlook and those focused on margin compression, debt, and auto-credit risks.

iShares Trust - iShares Russell 2000 Index Fund

iShares Russell 2000 ETF

IWM is drawing attention for holding up relatively well as technology and semiconductor stocks sell off, renewing discussion of a rotation into small caps. Traders debate whether the strength signals a lasting recovery or a temporary bounce, with elevated oil prices, yields, and uncertainty around Fed policy weighing on sentiment.

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Smirnoff Parent Diageo’s Stock In Spotlight After Company Warns of $200M Impact From Trump Tariffs: Retail’s Extremely Bearish

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The impact would impact mainly its tequila products, which must be made in Mexico

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Shares of spirits company Diageo plc ($DEO) were in the spotlight as the company warned about a potential impact of $200 million to its second half operating profit as a result of Trump's imminent Mexico and Canada tariffs, dragging down retail sentiment.The impact would impact mainly its tequila products, which must be made in Mexico, and also Canadian whisky, said the company. &nbsp;Diageo on Tuesday withdrew its medium-term guidance of organic net sales growth of between 5% and 7% due to the current macroeconomic and geopolitical uncertainty in its key markets.According to analyst firm Jefferies, nearly half of Diageo’s U.S. sales come from imports from Mexico and Canada. President Trump on Monday agreed to pause for 30 days his plans to levy 25% tariffs on Canada and Mexico imports.The impact of Trump tariffs are expected to impact its key supply chains, said the company, which said it is now taking a number of initiatives to mitigate the tariff impact and disruption to its business that tariffs may cause, according to an interim update on its first half fiscal performance.“We will also continue to engage with the U.S. administration on the broader impact that this will have on everyone supporting the U.S. hospitality industry, including consumers, employees, distributors, restaurants, bars and other retail outlets,” Debra Crew, Diageo’s CEO, said in a statement.However Chew assured that it was confident about a favorable industry fundamentals and its ability to outperform. Diageo declared interim dividend of $40.5, according to the statement.For the first half, it expects net sales to be about $10.9 billion, down 0.6% due to unfavorable foreign exchange, and partially offset by an increase in organic net sales. Its organic net sales returned to growth and increased by 1%, driven by a positive price/mix of 1.2pps, according to the company. "Our fiscal 25 first half results marked a return to growth, delivering organic net sales growth of 1% despite a challenging industry backdrop as consumers continue to navigate through inflationary pressures. Growth in four of our five regions was supported by market share gains," said Crew.Sentiment on Stocktwits dropped further in the ‘extremely bearish’ category. Message volumes remained ‘high’.<figure class="image"><img style="aspect-ratio:1294/302;" src="https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/Screenshot_2025_02_05_at_9_42_19_AM_8f07d66ea2.png" alt="Screenshot 2025-02-05 at 9.42.19 AM.png" width="1294" height="302"><figcaption>DEO sentiment meter and message volumes on Feb 4 as of 11:45 pm ET</figcaption></figure><stembedurl>https://stocktwits.com/john20242025/message/602617788</stembedurl>Diageo’s brands include Ketel One vodkas, Casamigos, DeLeon and Don Julio tequilas, Captain Morgan,Tanqueray and Guinness.Diageo stock is down 8/8% year-to-date.For updates and corrections, email newsroom[at]stocktwits[dot]com.

(Photo by Dimitrios Kambouris/Getty Images for National Board of Review)

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