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Applied Digital Corp. is a technology company, which engages in the provision of development and operation of data centers which provide computing power. It operates through the Data Center Hosting Business and HPC Hosting Business segments. The Data Center Hosting Business segment provides energized infrastructure services to crypto mining customers. The HPC Hosting Business segment focuses on the designing, constructing, and operating data centers tailored to support high power density applications like HPC and AI. The company was founded by Wesley Carl Cummins and Jason Zhang in May 2001 and is headquartered in Dallas, TX.

Applied Digital Corporation

Applied Digital is trending after reporting robust earnings, driven by significant revenue growth and an improving path to profitability. The company highlighted expanding hyperscaler lease agreements and advanced discussions for substantial new data center capacity, leading the community to anticipate strong long-term growth and discussing potential pressure on short positions.

Regencell Bioscience Holdings Ltd. is a early-stage bioscience company that focuses on research, development and commercialization of Traditional Chinese Medicine for the treatment of neurocognitive disorders and degeneration, specifically Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorder. The company was founded by Yat-Gai Au on October 30, 2014 and is headquartered in Hong Kong.

Regencell Bioscience Holdings Ltd

Regencell Bioscience is experiencing a significant surge, fueled by intense speculation around an extreme short squeeze. Community discussions highlight an exceptionally high borrow rate and near-zero shortable shares, leading many to compare its volatile price action to past low-float runners. Despite ongoing skepticism about the company's fundamentals and lack of revenue, retail investors view it as a high-stakes "casino play" within the Hong Kong nano-float sector.

SMX (Security Matters) Plc is a holding company, which engages in the provision of authentication solutions. It offers brand protection, authentication, and track and trace technology. The company was founded by Haggai Alon on July 1, 2022 and is headquartered in Dublin, Ireland.

SMX (Security Matters) Plc

SMX (Security Matters) PLC

SMX is experiencing a significant surge, driven by optimism around its blockchain-based Plastic Cycle Token technology for material verification and traceability. The trading community is actively discussing the stock's extremely low float and high cost to borrow, fueling widespread speculation about a potential short squeeze. Many are comparing its setup to other high-volatility runners, anticipating substantial further gains.

Apple, Inc. engages in the design, manufacture, and sale of smartphones, personal computers, tablets, wearables and accessories, and other varieties of related services. It operates through the following geographical segments: Americas, Europe, Greater China, Japan, and Rest of Asia Pacific. The Americas segment includes North and South America. The Europe segment consists of European countries, as well as India, the Middle East, and Africa. The Greater China segment comprises China, Hong Kong, and Taiwan. The Rest of Asia Pacific segment includes Australia and Asian countries. Its products and services include iPhone, Mac, iPad, AirPods, Apple TV, Apple Watch, Beats products, AppleCare, iCloud, digital content stores, streaming, and licensing services. The company was founded by Steven Paul Jobs, Ronald Gerald Wayne, and Stephen G. Wozniak in April 1976 and is headquartered in Cupertino, CA.

Apple Inc

Apple is actively discussed due to its notable stock decline and perceived underperformance relative to the broader market, which has seen peers like Alphabet gain significant ground on AI optimism. The community is expressing frustration over this sustained weakness, questioning Apple's AI strategy and valuation, despite some anticipating a bounce from oversold levels. This comes as the company also navigates a significant corporate shift with JPMorgan reportedly taking over the Apple Card from Goldman Sachs.

Novavax, Inc. Is a biotechnology company, which engages in the discovery, development, and commercialization of recombinant vaccines. The company was founded in 1987 and is headquartered in Gaithersburg, MD.

Novavax, Inc.

Novavax Inc

Novavax is trending with investors keenly anticipating strategic announcements, possibly a major partnership or acquisition, expected around the upcoming J.P. Morgan Healthcare Conference. Community sentiment is split between hope for a significant deal leveraging its advanced protein-based vaccine platform and superior COVID-flu combo data, and frustration over perceived management inaction and high short interest. The high short interest and Shah Capital's push for change are central to discussions amid broader biotech sector activity.

PMGC Holdings, Inc. is a physician-dispensed skincare company, which engages in the research and development of skincare formulations. It is involved in the production and commercialization of topical skincare products that contain its proprietary stem cell-derived Elevai Exosomes. The company was founded by Hatem Abou-Sayed, Braeden William Lichti, and Jordan R. Plews on June 9, 2020 and is headquartered in Newport Beach, CA.

PMGC Holdings Inc

PMGC Holdings Inc.

PMGC Holdings (ELAB) is generating significant buzz following a recent reverse stock split that drastically reduced its public float, alongside news of strategic ventures into the nuclear energy sector and aerospace certification. The community is heavily discussing the ultra-low float, anticipating a significant short squeeze or "float lock" similar to past runners, fueled by reports of extremely high cost-to-borrow fees and the company's robust cash position. Traders are actively debating its potential for a rapid, parabolic move given the tight share structure and new strategic ventures.

Bitcoin is the world's first decentralized cryptocurrency, created in 2009 by the pseudonymous Satoshi Nakamoto. It enables peer-to-peer electronic cash transactions without intermediaries like banks or governments, operating on a blockchain secured by Proof of Work mining and the SHA-256 cryptographic algorithm.   With a fixed supply cap of 21 million coins and programmatic halvings every four years that reduce miner rewards, Bitcoin is designed as a deflationary digital asset often called "digital gold." Its value stems from solving the double-spending problem without trusted intermediaries, creating the first truly scarce digital asset with censorship resistance and permissionless access that no government, corporation, or individual can control.  Bitcoin operates as a decentralized peer-to-peer network where transactions are recorded on a public ledger called the blockchain, distributed across thousands of computers globally. Transactions are grouped into blocks added approximately every 10 minutes through mining, where specialized computers compete to solve complex mathematical puzzles.   Bitcoin has achieved mainstream adoption through multiple vectors. The January 2024 SEC approval of 11 spot Bitcoin ETFs opened Bitcoin investment to traditional finance participants, and corporations like Strategy (formerly MicroStrategy) are using Bitcoin as a treasury reserve asset to protect against currency debasement, offering MSTR holders amplified exposure to Bitcoin.   The Bitcoin ecosystem continues to evolve with innovations like Ordinals, which emerged in January 2023 to enable NFT-like functionality directly on Bitcoin, and BRC-20 tokens, an experimental standard for creating fungible tokens using Ordinal inscriptions. BTCFi (Bitcoin Finance) represents emerging financial applications extending beyond Bitcoin's traditional role, with protocols like Babylon allowing Bitcoin holders to stake BTC to secure Proof of Stake chains.

Bitcoin

Bitcoin is trending amid a clear battle between bulls expecting new highs driven by institutional interest and potential crypto-friendly legislation, and bears citing historical cycles and alleged market manipulation for further downside. The community is closely watching key support and resistance levels as debates continue over its role as a "digital gold" versus a speculative asset. This strong divergence in perspective highlights the market's current uncertainty despite recent positive news surrounding digital asset treasury firms.

Ondas Holdings, Inc. engages in the development, marketing, and sale of wireless radio systems for secure, wide area mission-critical business-to-business networks. It operates through the Ondas Networks and Ondas Autonomous Systems segments. The Ondas Networks segment provides wireless connectivity solutions enabling mission-critical Industrial Internet applications and services. The Ondas Autonomous Systems segment designs, develops, and markets commercial drone solutions via the Optimus System and Scout System. The company was founded on December 22, 2014 and is headquartered in West Palm Beach, FL.

Ondas Holdings Inc

Ondas Holdings is trending following its Airobotics subsidiary securing a significant contract for autonomous drone systems with Israel's Ministry of Defense, coupled with its presence at the Singapore Airshow and upcoming investor events. The community is actively discussing strong institutional interest and the company's pivotal role in the rapidly growing defense and AI sectors, fueled by broader market tailwinds from increased global defense spending.

Strategy, Inc. engages in the provision of enterprise analytics and mobility software. The firm designs, develops, markets, and sells software platforms through licensing arrangements and cloud-based subscriptions and related services. Its product packages include Hyper. The company was founded by Michael J. Saylor and Sanjeev K. Bansal on November 17, 1989, and is headquartered in Vienna, VA.

Strategy Inc. - Ordinary Shares - Class A

Strategy

MicroStrategy (MSTR) is trending after MSCI shelved plans to exclude digital-asset treasury companies from its indexes, removing a significant structural overhang. This news has sparked intense debate, with bulls anticipating a potential short squeeze and a re-rating based on its Bitcoin holdings, while bears emphasize ongoing share dilution concerns and Bitcoin's recent weakness.

SU Group Holdings Ltd. engages in the provision of security-related engineering services, and security guarding and screening services. It operates through the Security-Related Engineering Services and Security Guarding and Screening Services segments. The company was founded by Ming Chan in 1998 and is headquartered in Hong Kong.

SU Group Holdings Ltd. - Ordinary Shares - Class A

SU Group Holdings Ltd

SU Group Holdings Ltd (SUGP) is trending due to intense community discussion centered on its ultra-low share float and significant short interest, leading to strong speculation about a potential short squeeze. Traders are keenly drawing comparisons to past high-volatility runners like SMX, with sentiment further fueled by its presence on the Reg SHO list, high cost to borrow, and anticipation of upcoming earnings and contract news as potential catalysts for a substantial price move.

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OptiNose (OPTN) Reports Q1 Loss, Tops Revenue Estimates

Karyopharm Therapeutics (KPTI) Reports Q1 Loss, Lags Revenue Estimates

Crinetics Pharmaceuticals, Inc. (CRNX) Reports Q1 Loss, Tops Revenue Estimates

Shares of Optinose, Inc. (OPTN) rocketed about 55% on Thursday after privately held Paratek Pharmaceuticals <a target="_blank" rel="noopener noreferrer nofollow" href="https://ir.optinose.com/news-releases/news-release-details/paratek-pharmaceuticals-acquire-optinose-creating-significant">announced</a> that it would buy the company for up to $330 million.The two companies have entered into a definitive merger agreement, under which Paratek will acquire Optinose and its product XHANCE, a drug-device combination product approved for the treatment of Chronic rhinosinusitis.Paratek will acquire Optinose's outstanding shares for $9 apiece in cash, representing a 50% premium to Optinose’s closing trading price of $6 on March 19, and up to $5 per share in contingent value rights (CVRs) if XHANCE achieves certain net revenue milestones.Paratek said in a statement that the boards of both companies have unanimously approved the transaction. It added that the transaction is expected to close as early as mid-2025, subject to customary closing conditions and approval by Optinose shareholders.Upon completion of the transaction, Optinose will be delisted from the NASDAQ Global market.Following the announcement, Optinose also <a target="_blank" rel="noopener noreferrer nofollow" href="https://ir.optinose.com/news-releases/news-release-details/optinose-cancels-fourth-quarter-and-full-year-2024-earnings-call">canceled</a> its earnings call for the fourth quarter of 2024, which was originally scheduled for March 20.Optinose CEO Ramy Mahmoud said that Paratek, with its commercial and medical capabilities, has the potential to increase awareness for Optinose’s XHANCE.“We are excited about the many ways in which this transaction creates opportunities for XHANCE to help more patients achieve better symptom control while creating near- and long-term value for Optinose's shareholders," he said.Paratek, meanwhile, said that the acquisition will help the company expand its portfolio.On Stocktwits, retail investor sentiment flipped from ‘extremely bearish’ to ‘extremely bullish’ (100/100) territory within the past 24 hours, coupled with ‘extremely high’ message volume.<figure class="image"><img style="aspect-ratio:810/181;" src="https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/Screenshot_2025_03_20_115139_png_df0e5340e2.webp" alt="Optinose’s Sentiment Meter and Message Volume as of 11:50 a.m. ET on March 20, 2025 | Source: Stocktwits" width="810" height="181"><figcaption>Optinose’s Sentiment Meter and Message Volume as of 11:50 a.m. ET on March 20, 2025 | Source: Stocktwits</figcaption></figure><a href="https://stocktwits.com/symbol/OPTN">Optinose shares</a> are up over 38% in 2025 but have lost over 60% in the past 12 months.Also See: <a href="https://stocktwits.com/news-articles/markets/equity/geo-stock-rises-on-ice-contract/ch7Nru4RbPQ">GEO Stock Rises On Immigration And Customs Contract With Annualized Revenue Potential Of $70M: Retail’s On The Fence</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

Retail investors on Stocktwits — where Altimmune has over 36,000 followers — have long speculated that the company could be a takeover target. | Image source: Getty Images

Optinose Shares Soar After Merger Agreement With Paratek Pharmaceuticals: Retail Sentiment Takes Flight 

Paratek will acquire Optniose's outstanding shares for $9 apiece in cash, representing a 50% premium to the stock’s closing trading price of $6 on March 19.

Equity

Paratek will acquire Optinose's outstanding shares for $9 apiece in cash, representing a 50% premium to the stock’s closing trading price of $6 on March 19, and up to $5 per share in contingent value rights if XHANCE achieves certain net revenue milestones.


OptiNose, Inc. operates as a pharmaceutical company. The firm engages in the development and commercialization of products for patients treated by ear, nose, throat, and allergy specialists. Its products include the XHANCE and ONZETRA Xsail. The company was founded by Per Gisle Djupesland and Helena Kyttari Djupesland in October 2000 and is headquartered in Yardley, PA.

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A few major private companies are being discussed as potential IPO candidates in 2026 — including SpaceX, Discord, Databricks, OpenAI, Anthropic, and Deel. IPO timelines can shift, but if one of these listings happens this year, which are you most excited to watch?

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