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Pyth Network is a decentralised oracle network designed to provide real-time financial market data to decentralised applications (dApps) across multiple blockchains. It allows developer to secure smart contracts with reliable, low-latency market data from institutional sources, and build apps with high-fidelity oracle feeds designed for mission-critical systems.

Pyth Network

Pyth Network is trending as the U.S. Department of Commerce selected it to verify and distribute economic data on-chain, marking a significant step for decentralized data adoption. The community is discussing the potential impact of this government partnership and comparing Pyth to other oracle services. Many believe this news and the increased volume could lead to a substantial price increase.

BrokeCoin is a meme-meets-utility cryptocurrency project operating under the ethos of Transparency, Community, and Respect. Formally registered as an LLC in Wyoming, USA, BrokeCoin is building an expansive ecosystem that combines light-hearted spirit of meme culture with real-world crypto utilities—spanning gaming, staking, NFTs, web services, and an e-commerce platform. Brokecoin believes in developing useful and interesting meme-inspired utilities to both service the crypto industry, and generate value for holders.

Brokecoin

Brokecoin is trending as the community rallies around upcoming airdrops and the imminent launch of the staking platform. Community members are actively celebrating recent gains and expressing excitement for new utilities. The coin's accessibility on centralized exchanges is also a key talking point.

Dog (Bitcoin) is a fully decentralized memecoin on the Bitcoin blockchain, backed by a community dedicated to onboarding millions of people to Bitcoin.  Dog is secured by the Bitcoin blockchain and exists on Bitcoin L1, marking a significant innovation compared to Bitcoin with just BTC. Dog is a Bitcoin Runes token with a minimal on-chain footprint, native to Bitcoin, and stored in UTXOs, just like Bitcoin.   What is the project about?  Dog does not do any paid promotion and is fully decentralized just like Bitcoin. Every influencer who chooses to post about Dog either received the airdrop or bought on secondary. Dog leverages the CC0 license to ensure that Dog is not owned by any single entity but rather by everyone. This had lead to the "DOG Army" independently creating art, apps, lotteries, plushies, websites, podcast, magazines, X account, IRL meetups, clothing lines, PFP collections, Telegram groups, and TikTok/Instagram about Dog.  What makes your project unique?  Dog was airdropped in the fairest memecoin launch ever. In early 2024, the Bitcoin Ordinals ecosystem came together in a full volunteer initiative that rewarded early adopters of the Ordinals Protocol. There was no team allocation, and 100% of the supply was airdropped for free. The airdrop algorithm favored neither whales nor influencers; it was determined by the community and made open-source for maximum transparency.

Dog (Bitcoin)

$DOG.X is trending as a Bitcoin-native meme coin built on the Runes protocol, sparking discussions about its role in driving on-chain activity and benefiting miners through transaction fees. The community highlights its unique position within the Bitcoin ecosystem, with some noting significant holdings by entities like $CBLO. Despite some skepticism, many see potential for substantial growth, drawing comparisons to previous meme coin successes.

The mission of the Worldcoin project is to build the world’s largest identity and financial network as a public utility, giving ownership to everyone. A key component of the Worldcoin project is the development of the foundational infrastructure that will be important for a world where AI plays an increasingly large role.  The Worldcoin system revolves around World ID, a privacy-preserving global identity network. World ID enables users to verify their humanness online while maintaining their privacy through zero-knowledge proofs.  Using World ID, individuals will be able to prove that they are a real, unique human to any platform that integrates with the protocol, including to web3 systems, social networking sites, and governmental programs. This will enable fair airdrops or token/NFT sales, provide protection against bots/sybil attacks on social media, and enable the fairer distribution of limited governmental resources. Furthermore, World ID can also enable global democratic processes and novel forms of governance (e.g., via quadratic voting), and it may eventually show a path to AI-funded UBI. The Worldcoin token (WLD), alongside World ID, will let users participate in governing the Worldcoin protocol.   To engage with the Worldcoin protocol, individuals must first download a first wallet app that supports the creation of a World ID. Users visit a physical imaging device called the Orb to get their World ID Orb-verified. Orbs are operated by a network of independent local businesses called Orb Operators. The Orb uses multispectral sensors to verify humanness and uniqueness to issue an Orb-verified World ID, with all images being promptly deleted on-device per default (absent explicit consent to Data Custody). All Orb-verified World IDs holders are entitled to claim recurring grants of free WLD tokens, subject to certain availability restrictions. The WLD token is designed as a utility token with governance properties.

Worldcoin

Worldcoin is experiencing increased attention as the community speculates on potential breakouts and upcoming developments related to Sam Altman's projects. The crypto's association with Altman and its unique use case related to AI are key points of discussion. However, concerns remain around its tokenomics, use case and the overall concept of iris-scanning for identification.

Brewski

Brewski.X is trending as the community highlights unusual whale activity and labels it a potential runner. The token appears to be resonating with a patriotic theme, referencing American spirit and camaraderie. Chatter includes mentions of other meme coins and potential pumps.

Kaspa is a proof-of-work cryptocurrency which implements the GHOSTDAG protocol. Unlike traditional blockchains, GHOSTDAG does not orphan blocks created in parallel, rather allows them to coexist and orders them in consensus. Whereby our blockchain is actually a blockDAG; you can see GHOSTDAG in action in a real time blockDAG visualizer). This generalization of Nakamoto consensus allows for secure operation while maintaining very high block rates (currently one block per second, aiming for 10/sec, dreaming of 100/sec) and minuscule confirmation times dominated by internet latency (cf. chapter 6 of the the paper for some initial benchmarks). The Kaspa implementation includes a lot of cool features and subprotocols including Reachability to query the DAG's topology, Block data pruning (with near-future plans for block header pruning), SPV proofs, and later subnetwork support which will make future implementation of layer 2 solutions much easier.

Kaspa

Kaspa is trending as the community anticipates the upcoming Crescendo hard fork and smart contract capabilities, leading to speculation about potential listings on major exchanges. Despite some concerns about the recent price action and comparisons to other projects, many holders remain bullish, citing Kaspa's technology, scalability, and potential for real-world applications. Discussions also revolve around the impact of macro factors and potential partnerships on Kaspa's future.

Numeraire

Numeraire is trending as community members discuss its potential for significant gains, fueled by news of JP Morgan's investment in Numerai, an AI-based crypto hedge fund; this move doubled Numerai's AUM and sparked bullish sentiment, with some anticipating a run to previous highs. Traders are closely watching key price levels, citing unusual volume and buying pressure, while also debating its utility and potential within the broader AI and decentralized finance (DeFi) landscape.

Merging the worlds of decentralized computation and gaming to scale compute while you have a blast!  $GMRX: A token for our entire economy and our fully-built, plug-and-play cloud computing, games distribution and gamer experiences platform.  Decentralized computation:  1. Targeting the 1.6 billion desktop gamers globally.  2. Biggest active decentralized GPU sharing network.  3. Automatic GPU monetization (AI, Render & Mining Jobs).  Gaming:  1. We own Gaimin Gladiators, one of the top esports organizations in the world.  2. Integrated web2 and web3 gaming platform with NFT functionality and in-app marketplace.

Gaimin

Gaimin ($GMRX.X) is trending amid discussions about its platform downloads and upcoming utility features. The community is focused on the potential release of 'PRO,' which is rumored to provide the highest payouts for mining. Some users are also pointing to Gaimin as a future mover due to its AI, DePIN, and gaming applications.

This platform is engineered to unlock the full potential of Real-World Assets (RWAs) by bringing them onto the XRP Ledger with unparalleled efficiency. Our purpose is to democratize access to high-value assets by providing a streamlined, end-to-end solution for tokenization. Functionally, we offer tools for asset verification, compliant legal wrapping, and the minting of RWA tokens. The project's core utility is twofold: for asset owners, it unlocks immediate liquidity and access to global capital markets; for investors, it offers fractional, transparent, and liquid access to investment classes like private equity and infrastructure bonds. We leverage the XRPL's native speed and built-in DEX to ensure low-cost transactions and instant settlement, setting a new standard for RWA interoperability and finance.

VOLT

VOLT ($XVM.X) is trending as the community discusses its potential as the next big Real World Asset (RWA) coin. Investors are excited about its early stage and are speculating about significant market cap growth, while also inquiring about where to purchase it. Some users are reporting issues sending the coin to a ledger wallet.

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Direxion Daily S&P Biotech Bull 3X Shares

LABU is trending due to discussions around market sentiment, technical analysis, and potential impacts from upcoming economic reports like CPI and PPI. Community members are weighing bullish and bearish scenarios, with some focusing on Elliot Wave patterns and key price levels for potential entry or exit points. Additionally, potential policy changes, such as pharmaceutical tariffs and their implications for the biotech sector, are being closely monitored.

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OptiNose (OPTN) Reports Q1 Loss, Tops Revenue Estimates

Karyopharm Therapeutics (KPTI) Reports Q1 Loss, Lags Revenue Estimates

Crinetics Pharmaceuticals, Inc. (CRNX) Reports Q1 Loss, Tops Revenue Estimates

Shares of Optinose, Inc. (OPTN) rocketed about 55% on Thursday after privately held Paratek Pharmaceuticals <a target="_blank" rel="noopener noreferrer nofollow" href="https://ir.optinose.com/news-releases/news-release-details/paratek-pharmaceuticals-acquire-optinose-creating-significant">announced</a> that it would buy the company for up to $330 million.The two companies have entered into a definitive merger agreement, under which Paratek will acquire Optinose and its product XHANCE, a drug-device combination product approved for the treatment of Chronic rhinosinusitis.Paratek will acquire Optinose's outstanding shares for $9 apiece in cash, representing a 50% premium to Optinose’s closing trading price of $6 on March 19, and up to $5 per share in contingent value rights (CVRs) if XHANCE achieves certain net revenue milestones.Paratek said in a statement that the boards of both companies have unanimously approved the transaction. It added that the transaction is expected to close as early as mid-2025, subject to customary closing conditions and approval by Optinose shareholders.Upon completion of the transaction, Optinose will be delisted from the NASDAQ Global market.Following the announcement, Optinose also <a target="_blank" rel="noopener noreferrer nofollow" href="https://ir.optinose.com/news-releases/news-release-details/optinose-cancels-fourth-quarter-and-full-year-2024-earnings-call">canceled</a> its earnings call for the fourth quarter of 2024, which was originally scheduled for March 20.Optinose CEO Ramy Mahmoud said that Paratek, with its commercial and medical capabilities, has the potential to increase awareness for Optinose’s XHANCE.“We are excited about the many ways in which this transaction creates opportunities for XHANCE to help more patients achieve better symptom control while creating near- and long-term value for Optinose's shareholders," he said.Paratek, meanwhile, said that the acquisition will help the company expand its portfolio.On Stocktwits, retail investor sentiment flipped from ‘extremely bearish’ to ‘extremely bullish’ (100/100) territory within the past 24 hours, coupled with ‘extremely high’ message volume.<figure class="image"><img style="aspect-ratio:810/181;" src="https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/Screenshot_2025_03_20_115139_png_df0e5340e2.webp" alt="Optinose’s Sentiment Meter and Message Volume as of 11:50 a.m. ET on March 20, 2025 | Source: Stocktwits" width="810" height="181"><figcaption>Optinose’s Sentiment Meter and Message Volume as of 11:50 a.m. ET on March 20, 2025 | Source: Stocktwits</figcaption></figure><a href="https://stocktwits.com/symbol/OPTN">Optinose shares</a> are up over 38% in 2025 but have lost over 60% in the past 12 months.Also See: <a href="https://stocktwits.com/news-articles/markets/equity/geo-stock-rises-on-ice-contract/ch7Nru4RbPQ">GEO Stock Rises On Immigration And Customs Contract With Annualized Revenue Potential Of $70M: Retail’s On The Fence</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

Retail investors on Stocktwits — where Altimmune has over 36,000 followers — have long speculated that the company could be a takeover target. | Image source: Getty Images

Optinose Shares Soar After Merger Agreement With Paratek Pharmaceuticals: Retail Sentiment Takes Flight 

Paratek will acquire Optniose's outstanding shares for $9 apiece in cash, representing a 50% premium to the stock’s closing trading price of $6 on March 19.

Equity

Paratek will acquire Optinose's outstanding shares for $9 apiece in cash, representing a 50% premium to the stock’s closing trading price of $6 on March 19, and up to $5 per share in contingent value rights if XHANCE achieves certain net revenue milestones.


Insights Ahead: OptiNose's Quarterly Earnings

Optinose to Present at the Needham Virtual Healthcare Conference

YARDLEY, Pa., April 04, 2024 (GLOBE NEWSWIRE) -- Optinose (NASDAQ:OPTN), a pharmaceutical company focused on patients treated by ear, nose and throat (ENT) and allergy specialists, today announced...

Ramy A. Mahmoud Sells 19,198 Shares of OptiNose, Inc. (NASDAQ:OPTN) Stock

OptiNose, Inc. (NASDAQ:OPTN  Get Free Report) CEO Ramy A. Mahmoud sold 19,198 shares of the stock in a transaction that occurred on Monday, March 18th. The shares were sold at an average price...

Lake Street Capital Boosts OptiNose (NASDAQ:OPTN) Price Target to $4.00

OptiNose (NASDAQ:OPTN  Free Report) had its price target raised by Lake Street Capital from $3.00 to $4.00 in a research note issued to investors on Monday, Benzinga reports. The brokerage...

OptiNose (NASDAQ:OPTN) PT Raised to $4.00

OptiNose (NASDAQ:OPTN  Free Report) had its price target raised by Lake Street Capital from $3.00 to $4.00 in a report published on Monday, Benzinga reports. The brokerage currently has a buy...

Optinose price target raised by $1 at Lake Street, here's why

See the rest of the story here.

thefly.com provides the latest financial news as it breaks. Known as a leader in market intelligence, The Fly's real-time, streaming news feed keeps individual...

OptiNose, Inc. operates as a pharmaceutical company. The firm engages in the development and commercialization of products for patients treated by ear, nose, throat, and allergy specialists. Its products include the XHANCE and ONZETRA Xsail. The company was founded by Per Gisle Djupesland and Helena Kyttari Djupesland in October 2000 and is headquartered in Yardley, PA.

Fiscal Period	Estimated	Reported	Surprise	Result
Q2 '25	-$0.40	--	--	N/A
Q1 '25	-$0.74	--	--	N/A
Q4 '24	-$0.61	-$0.03	95.05%	BEAT
Q3 '24	-$0.05	$0.00	100.00%	BEAT
Q2 '24	-$0.08	-$0.07	9.50%	BEAT

OPTN
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