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ImmunityBio, Inc. is a clinical stage immunotherapy company. It develops next generation therapies that drive immunogenic mechanisms for defeating cancers and infectious diseases. The company's immunotherapy platform activates both the innate and adaptive immune systems to create long term immunological memory. ImmunityBio was founded by Patrick Soon-Shiong in 2014 and is headquartered in San Diego, CA.

ImmunityBio Inc

The community is buzzing around ImmunityBio (IBRX) as founder Dr. Patrick Soon-Shiong appears in highly anticipated prime-time interviews to discuss breakthrough cancer treatments, with investors actively debating the potential for a significant short squeeze and an impactful business update next week that could challenge traditional pharma.

Applied Optoelectronics, Inc. engages in the design and manufacture of optical communications products. Its products include optical devices, such as laser diodes, photodiodes, related modules and circuitry, and equipment for applications in fiber-to-the-home, cable television, point to point communications, and wireless. The company was founded by Chih Hsiang Lin on February 28, 1997 and is headquartered in Sugar Land, TX.

Applied Optoelectronics Inc

Applied Optoelectronics is surging following a strong earnings beat and upbeat guidance for AI/data center demand for its 400G and 800G transceivers, alongside significant analyst price target upgrades. The rally is fueled by short-squeeze momentum and optimism for future growth, though community discussion also reflects concerns over the company's valuation and a recent equity offering.

Vanguard Group, Inc. - Vanguard Total Stock Market ETF

Vanguard Total Stock Market ETF

Vanguard Total Stock Market ETF ($VTI) is generating significant discussion as a bellwether for the U.S. market, with investors observing strong inflows and its proximity to all-time highs. The community is weighing these positive signals against prevailing political and economic uncertainties, prompting ongoing debate about diversification and market direction.

A project grown out of the community's love and passion for the weed culture. Launched around early 2025, $weedcoin, “Like Bitcoin but way higher,” emphasizes its alignment with cannabis culture and a laid-back vibe. Unlike other Weed communities, this project leans heavily into community engagement over technical utility, aiming to build a “stoner community” through social media presence and decentralized governance. We also aim to focus on onboarding web2 businesses and users onto web3 through the token.

Weedcoin

WEEDCOIN is gaining significant attention as its community rallies around the approaching 4/20 festivities, emphasizing its robust culture, unity, and long-term belief, positioning it as a decentralized payment solution for the evolving global cannabis industry.

Eos Energy Enterprises, Inc. designs, manufactures, and deploys battery storage solutions for the electricity industry. It offers the Eos Znyth DC battery system product which designs to meet the requirements of the grid-scale energy storage market. The company was founded in 2008 and is headquartered in Edison, NJ.

Eos Energy Enterprises Inc - Ordinary Shares - Class A

Eos Energy is trending after a substantial earnings and revenue miss, coupled with weak 2026 guidance, has sent the stock plummeting, leading to widespread investor frustration and calls for management accountability. While many fear further downside due to perceived incompetence and potential dilution, a segment of the community views the steep decline as an overreaction, highlighting the company's growing backlog and role in the crucial energy storage market.

Aardvark Therapeutics, Inc. operates as a biotechnology company. It engages in the development of a novel, small-molecule therapeutics for the treatment of metabolic diseases. The company was founded by Tien Lee in 2017 and is headquartered in San Diego, CA.

Aardvark Therapeutics Inc.

Aardvark Therapeutics Inc

Aardvark Therapeutics is a top trending stock after voluntarily pausing its Phase 3 trial for ARD-101 due to cardiac safety signals, sparking widespread investor concern and negative sentiment around its pipeline and competitive position in Prader-Willi Syndrome treatment.

Hawaiian Electric Industries, Inc. is a holding company, which engages in electric utility and non-regulated renewable and sustainable infrastructure businesses. The company was founded by C. Dudley Pratt Jr. in 1981 and is headquartered in Honolulu, HI.

Hawaiian Electric Industries, Inc.

Hawaiian Electric is trending as investors assess recent earnings reports and ongoing legislative efforts to cap wildfire liabilities against concerns of significant share dilution and the substantial cost of its $1.99 billion settlement. The community is sharply divided between bulls anticipating a strong recovery fueled by institutional accumulation and bears warning of sustained selling pressure from future capital raises.

Soleno Therapeutics, Inc. operates as clinical-stage biopharmaceutical company, which engages in the development and commercialization of novel therapeutics for the treatment of rare diseases. It focuses on the treatment of metabolic and neurobehavioral disorder. It offers its lead candidate, Diazoxide Choline Controlled-Release (DCCR), an oral tablet for the treatment of Prader-Willi Syndrome (PWS). The company was founded on August 25, 1999 and is headquartered in Redwood City, CA.

Soleno Therapeutics Inc

Soleno Therapeutics is trending sharply following the FDA approval of VYKAT XR, the first therapy for Prader-Willi Syndrome, a catalyst amplified by competitor trial failures which is sparking intense community debate over its significant market potential and valuation amid ongoing short-seller challenges.

SPDR Series Trust - State Street SPDR S&P Regional Banking ETF

SPDR S&P Regional Banking ETF

Regional banks are a major talking point amid heightened concerns over rising credit stress, recent bad loan disclosures by several institutions, and the closure of a small bank, igniting fears of a broader banking crisis. Yet, the community remains divided as others highlight the sector's technical resilience, ongoing consolidation, and potential benefits from future rate cuts or regulatory adjustments.

SSgA Active Trust - State Street Health Care Select Sector SPDR ETF

Health Care Select Sector SPDR Fund

The Health Care Select Sector SPDR Fund ($XLV) is trending due to significant market rotation into defensive sectors amid broader market volatility, with many observing its strong performance and potential for a breakout to new highs. Simultaneously, President Trump's proposed 100% tariffs on branded pharmaceuticals are a major talking point, raising concerns about potential impacts on drugmakers and supply chains within the sector.

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ITC Ltd.

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Shares of video-streaming platform Roku rose over 9% on Friday after Guggenheim reportedly upgraded the stock to ‘Buy’ from ‘Neutral’ while keeping a price target of $75.The brokerage expects investor enthusiasm to continue into the third quarter as the firm makes progress toward expanding video inventory advertising sales through third-party demand-side platforms and improved home screen monetization.Guggenheim also said its revised rating reflects the firm’s financial estimates being ahead of consensus for 2024 and 2025 and its attractive relative valuation.The brokerage, however, noted that its primary concerns remain unchanged. One of the firm’s worries is that leadership has been slow to take advantage of its dominant position in the connected TV marketplace. Guggenheim also noted that competition in the advertising and CTV marketplaces could pressure financial performance.Following the upgrade, retail sentiment on Roku shifted into ‘bullish’ territory (84/100) from ‘neutral’ zone a day ago, accompanied by high message volume (81/100). &nbsp;<figure class="image"><a href="https://stocktwits.com/symbol/ROKU"><img style="aspect-ratio:1898/520;" src="https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/Screenshot_2024_08_23_at_10_23_13_AM_9db781beab.png" alt="Roku sentiment meter as of 10:07 a.m. ET on August 23, 2024" width="1898" height="520"></a><figcaption>Roku sentiment meter as of 10:07 a.m. ET on August 23, 2024</figcaption></figure>During the second quarter of fiscal year 2024, Roku reported a 14% year-over-year (YoY) rise in &nbsp;its net revenue at $965.20 million. However, the company’s average revenue per user (ARPU) remained flat at $40.68 YoY.The company said continued growth in scale and engagement, along with the execution of its monetization initiatives has positioned it strongly in the ongoing shift to streaming. For the second half of 2024, the firm expects these initiatives to help accelerate revenue from advertising activities.For the third quarter, the company estimates 11% YoY growth in its total net revenue at $1.01 billion with Platform revenue growing 9% YoY and Devices revenue growing 24% YoY.Stocktwits users are enthusiastic about the upgrade. A bullish user believes the stock may cross the $99 mark by the end of the year.<stembedurl>https://stocktwits.com/stanfrombrooklyn/message/583920998</stembedurl>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;

Guggenheim expects investor enthusiasm to continue into the third quarter 

Roku Soars 9% After Guggenheim Upgrade: Here’s What Retail Is Thinking

Guggenheim said its revised rating reflects the firm’s financial estimates being ahead of consensus for 2024 and 2025 and its attractive relative valuation. 

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