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ImmunityBio, Inc. is a clinical stage immunotherapy company. It develops next generation therapies that drive immunogenic mechanisms for defeating cancers and infectious diseases. The company's immunotherapy platform activates both the innate and adaptive immune systems to create long term immunological memory. ImmunityBio was founded by Patrick Soon-Shiong in 2014 and is headquartered in San Diego, CA.

ImmunityBio Inc

ImmunityBio is generating significant buzz following positive regulatory advancements for its ANKTIVA therapy, with the FDA outlining a path to resubmission for papillary bladder cancer that requires no new clinical trials. This news, combined with recent international approvals, is fueling strong community sentiment around the potential for a "cancer cure" and intense discussions anticipating a substantial short squeeze.

SSgA Active Trust - SPDR S&P 500 ETF Trust

The SPY is trending as market participants react to heightened geopolitical tensions, specifically former President Trump's recent tariff threats against NATO allies over Greenland and an anticipated Supreme Court ruling on presidential tariff authority. This has sparked a fierce debate among investors, with some advocating to "buy the dip" and anticipating a rapid "Taco Trade" rebound, while others warn of a significant market correction. Adding to the volatility are concerns surrounding Japan's bond market instability, creating a complex and uncertain trading environment.

Novavax, Inc. Is a biotechnology company, which engages in the discovery, development, and commercialization of recombinant vaccines. The company was founded in 1987 and is headquartered in Gaithersburg, MD.

Novavax, Inc.

Novavax Inc

Novavax is trending after announcing a non-exclusive license agreement with Pfizer for its Matrix-M adjuvant, providing significant validation for the technology. This deal, building on previous collaborations, is driving community excitement and fueling discussions about the adjuvant's potential applications and the company's future partnerships amidst notable short interest.

Invesco Capital Management LLC - Invesco QQQ Trust Series 1

QQQ is trending as former President Trump's renewed threats of tariffs on NATO allies, particularly over the acquisition of Greenland, spark fears of a trade war with Europe. This escalating geopolitical tension is causing widespread market jitters and calls for caution, though many investors are also discussing it as a potential "buy the dip" opportunity for growth stocks.

SPDR Gold Trust - SPDR Gold Shares

SPDR Gold Shares ETF

SPDR Gold Shares ETF (GLD) is trending strongly as renewed geopolitical tensions, including recent tariff threats concerning European countries over Greenland, fuel a broad flight to safety. The community views gold as a crucial hedge against eroding fiat currency confidence and economic instability, driving prices to consistent new highs. Many are discussing significant further appreciation as these global uncertainties persist.

Netflix, Inc. engages in providing entertainment services. It also offers activities for leisure time, entertainment video, video gaming, and other sources of entertainment. It operates through the United States and International geographic segments. The company was founded by Marc Randolph and Wilmot Reed Hastings on August 29, 1997 and is headquartered in Los Gatos, CA.

Netflix Inc.

Netflix Inc

Netflix is currently a major talking point among investors, primarily driven by its upcoming earnings report and the proposed all-cash acquisition of Warner Bros. Discovery assets, which has sparked a debate over potential growth versus debt concerns. The community is closely watching for strong ad-tier performance and subscriber metrics, particularly after a previous tax-related earnings miss, with sentiment split on whether recent oversold conditions signal a significant rebound or continued volatility.

BlackRock Institutional Trust Company N.A. - iShares 20+ Year Treasury Bond ETF

iShares 20+ Year Treasury Bond ETF

TLT is trending amid intense debate surrounding the Federal Reserve's independence, fueled by a federal probe into its Chair and the administration's aggressive policy maneuvers impacting bond markets. Investors are actively discussing whether long-term treasuries offer a crucial hedge against a potential economic slowdown or face further headwinds from escalating national debt and geopolitical uncertainty.

AppLovin Corp. engages in the development and operation of a mobile marketing platform. It offers AppDiscovery, MAX, Adjust, and SparkLabs. Its software-based platform caters to mobile application developers to improve the marketing and monetization of applications. The company was founded by Andrew Karam, John Krystynak, and Adam Foroughi in 2011 and is headquartered in Palo Alto, CA.

Applovin Corp - Ordinary Shares - Class A

Applovin Corp

Applovin ($APP) is experiencing significant volatility and a notable price decline following a new short report alleging the company's involvement in money laundering. This report has sparked intense debate among investors, with many attributing the drop to market manipulation and viewing it as a buying opportunity, while others express concern over the serious accusations despite recent bullish analyst upgrades.

Corvus Pharmaceuticals, Inc. engages in the development of immune modulator product candidates with the potential to treat solid cancers, T-cell lymphomas, autoimmune diseases, and infectious diseases. Its product pipeline includes B Cell Activator and Anti-CD73, Adenosine Production Inhibitor Anti-CD73, ITK Inhibitor, A2AR Inhibitor, Anti-CXCR2, and A2BR Inhibitor. The company was founded by Richard A. Miller, Peter A. Thompson, Joseph J. Buggy, and Erik Verner on January 27, 2014 and is headquartered in South San Francisco, CA.

Corvus Pharmaceuticals Inc

Corvus Pharmaceuticals is trending due to overwhelmingly positive data from its Phase 1 clinical trial of soquelitinib for atopic dermatitis, with community discussions highlighting its strong efficacy in treatment-resistant patients. Investors are actively debating the potential for this novel oral ITK inhibitor to disrupt the significant atopic dermatitis market, fueling speculation of future partnerships or an acquisition and validating its broader immune-modulating platform.

ServiceNow, Inc. engages in the provision of an end-to-end workflow automation platform for digital businesses. Its Now Platform is a cloud-based solution embedded with artificial intelligence (AI) and machine learning (ML). The company was founded by Frederic B. Luddy in June 2004 and is headquartered in Santa Clara, CA.

ServiceNow Inc

ServiceNow is trending amidst a broader software sector selloff, with community discussion centered on whether AI advancements pose a threat or opportunity. Recent news of a key OpenAI partnership and the strategic acquisition of cybersecurity firm Armis, alongside positive analyst reiterations, fuels debate over the stock's oversold status.

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INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Instil Bio, Inc. - TIL

INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Instil Bio, Inc. - TIL INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Instil Bio...

Instil Bio Pulls Plug On Lead Drug Development

Instil Bio stock falls after the company ends development of its lead cancer drug and exits a licensing deal, raising new questions about its pipeline and next steps.read more...

Instil Bio, Inc. (TIL) Is Up 4.07% in One Week: What You Should Know 

Wall Street Analysts Think Instil Bio (TIL) Could Surge 246.68%: Read This Before Placing a Bet

Are You Looking for a Top Momentum Pick? Why Instil Bio, Inc. (TIL) is a Great Choice

Summit Therapeutics Stock Nosedives on Mixed NSCLC Study Results

Instil Bio (TIL) Upgraded to Buy: What Does It Mean for the Stock?

Wall Street Analysts Believe Instil Bio (TIL) Could Rally 343.63%: Here's is How to Trade

<a href="https://stocktwits.com/symbol/TIL">Instil Bio’s stock</a> surged over 25% on Tuesday to levels last seen in early December after Jefferies upgraded the&nbsp;shares to ‘Buy’ from ‘Hold,’ with a new price target of $52 — more than double its current level.&nbsp;The upgrade reflects Jefferies’ confidence in the potential of Instil’s lead asset, SYN-2510, a novel PD-L1xVEGF bispecific antibody targeting multiple solid tumor cancers.Jefferies highlighted SYN-2510 as an “early mover” in the competitive cancer drug space, with significant upside expected from its planned clinical trials.&nbsp;A U.S. Phase 1b/2 study in non-small cell lung cancer (NSCLC) is scheduled to begin in the second half of 2025, focusing on driver gene mutation-negative non-squamous and squamous NSCLC patients.&nbsp;This trial will explore SYN-2510 in combination with chemotherapy, a promising strategy in frontline treatment settings.SYN-2510 is part of a global registrational strategy with China’s ImmuneOnco Biopharmaceuticals.&nbsp;In late 2024, ImmuneOnco started a Phase 1b/2 chemo combination study in China for frontline NSCLC. The collaboration aims to generate clinical proof-of-concept data in multiple solid tumors, with updates anticipated in early 2025.&nbsp;If successful, both companies may initiate joint randomized Phase 3 chemotherapy combination trials for NSCLC and triple-negative breast cancer (TNBC) in 2025.<figure class="image"><img style="aspect-ratio:1318/324;" src="https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/TIL_sentiment_and_message_volume_Jan_7_premarket_960267c1cd.png" alt="TIL sentiment and message volume Jan 7 premarket.png" width="1318" height="324"><figcaption>TIL sentiment and message volume Jan 7 as of 11:45 am ET | source: Stocktwits</figcaption></figure>Retail investors on Stocktwits reacted positively, pushing sentiment to ‘extremely bullish’ and boosting its message volume.&nbsp;<stembedurl>https://stocktwits.com/Blackcoupe369/message/599159968</stembedurl>Jefferies also noted that the stock is trading at cash value, which, combined with SYN-2510’s potential, suggests substantial growth opportunities.Instil reported $122.9 million in cash reserves as of September 2024, saying it was sufficient to fund its operations through at least 2026.&nbsp;The stock has climbed over 240% in the past year, driven by optimism around its innovative cancer therapies and impending trials, making it a standout player in the small-cap oncology space.For updates and corrections, email newsroom[at]stocktwits[dot]com.

Woman examining laboratory samples - stock photo | Image source: Getty Images

Instil Bio Stock Soars After Jefferies Upgrade On 'Early Mover' Cancer Drug Candidate: Retail Jubilant

Jefferies highlighted SYN-2510 as an “early mover” in the competitive cancer drug space, with significant upside expected from its planned clinical trials.

Equity

Shares of Instil Bio Inc. (TIL) skyrocketed over 60% on Friday, placing it among the top five gainers on U.S. stock exchanges and one of the top 20 trending tickers on Stocktwits, where message volume jumped 340%.The surge came after Baird raised its price target on the stock to $180, implying a 146% upside, while maintaining an ‘Outperform’ rating.Baird’s optimism is growing enthusiasm for Instil’s PD-L1xVEGF bispecific antibody, driven by positive data from peers like Akeso’s ivonescimab and Summit’s BNT327 in the same space.Analysts noted recent results and data released ahead of the European Society for Medical Oncology (ESMO) meeting have increased faith in this drug class for treating cancers like triple-negative breast, RCC, and head and neck.Baird expects continued momentum in this therapeutic area at ESMO, seeing further growth opportunities for Instil Bio. Despite the recent rally, the brokerage believes the stock remains undervalued, suggesting more room for gains.Baird’s price target hike follows H.C. Wainwright’s upgrade a day earlier, when it raised its price target from $25 to $40 with a ‘Buy’ rating. Wainwright expressed increased confidence in Instil’s SYN-2510, highlighting its strong antitumor synergy compared to traditional VEGF blockers and PD-L1 antibodies.Instil also announced a restructuring plan last week, including shutting down operations in Manchester, U.K., and laying off its remaining workforce there. The restructuring will cost up to $5.5 million, including $2.2 million in asset impairments and $2 million in severance.<figure class="image"><a href="https://stocktwits.com/symbol/TIL"><img style="aspect-ratio:1320/324;" src="https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/TIL_sentiment_and_message_volume_Sep_13_0d4fea2fed.png" alt="TIL sentiment and message volume Sep 13.png" width="1320" height="324"></a><figcaption>TIL sentiment and message volume Sep 13</figcaption></figure>Despite bullish analyst notes, retail investors remain wary. Sentiment on Stocktwits is ‘extremely bearish,’ with users questioning the sustainability of the stock’s rapid ascent.“$TIL 13$ last week, now 77$,” noted one user.<stembedurl>https://stocktwits.com/patbourque/message/585998096</stembedurl>Another warned, “$TIL from $9 to $70 in a few days!!! This is not going to go well next week.”<stembedurl>https://stocktwits.com/ProBulish/message/585995548</stembedurl>Adding to concerns, Instil’s fundamentals look shaky. The company reported zero revenue in the latest quarter, only $6.78 million in cash, and holds a $52.1 million mortgage construction loan on its Tarzana, California property, with an option to draw an additional $32.9 million.Instil Bio has soared 624% in the last month, and retail investors are exercising caution for now.Read next: <a href="https://stocktwits.com/news/markets/equity/mstr-stock-rises-on-bitcoin-buy-retail-bullish/c7z62Y5R5B">MicroStrategy Stock Surges On $1B Bitcoin Buy Amid Crypto Dip: Retail Bulls Rejoice</a> &nbsp;

Instil Bio Soars On Baird’s Price Target Boost: Retail Remains On Sidelines Amid Wild Surge

Despite a recent rally in Instil Bio shares, Baird believes the stock remains undervalued, suggesting more room for gains.

Instil Bio, Inc. is a clinical-stage biopharmaceutical company engaged in developing a cell therapy pipeline of autologous tumor infiltrating lymphocyte therapies for the treatment of patients with cancer. The company was founded in August 2018 and is headquartered in Dallas, TX.

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