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SLV is experiencing extreme volatility as the CME has again raised margin requirements, fueling a heated debate among investors. Bulls contend this is a desperate attempt to suppress prices ahead of anticipated industrial demand and China's impending export restrictions on silver. Conversely, bears view the current action as a "pump and dump," warning of a significant correction similar to past cycles.

Vanda Pharmaceuticals, Inc. engages in the development and commercialization of therapies for high unmet medical needs. The firm intends to treat schizophrenia, jet lag disorder, atopic dermatitis, central nervous system disorders, and circadian rhythm sleep disorder. Its product portfolio includes HETLIOZ, Fanapt, Tradipitant, Trichostatin, and AQW051. The company was founded by Mihael Hristos Polymeropoulos and Argeris N. Karabelas in 2002 and is headquartered in Washington, DC.

Vanda Pharmaceuticals Inc

Vanda Pharmaceuticals is trending significantly after securing FDA approval for tradipitant, a novel motion sickness drug and the first in nearly 40 years. This approval, coupled with compelling data demonstrating tradipitant's effectiveness in reducing GLP-1 induced nausea and vomiting, has ignited widespread community discussion about its blockbuster potential as an add-on therapy for the rapidly expanding weight-loss drug market. Traders are actively debating potential acquisition interest from major pharmaceutical companies and anticipating substantial upside across VNDA's pipeline.

Litecoin is a peer-to-peer cryptocurrency created by Charlie Lee. It was created based on the Bitcoin protocol but differs in terms of the hashing algorithm used. Litecoin uses the memory intensive Scrypt proof of work mining algorithm. Scrypt allows consumer-grade hardware such as GPU to mine those coins.  Why Litecoin? Litecoin is a cryptocurrency that has evolved from Bitcoin after its own popularity in the industry, this alternative, or ‘altcoin’ has emerged to allow investors to diversify their digital currency package, according to Investopedia. Litecoin is one of the most prominent altcoins and was created by former Google employee and Director of Engineering at Coinbase, Charlie Lee. Litecoin was the first to alter Bitcoin and the most significant difference is that it takes 2.5 minutes for Litecoin to generate a block, or transaction, in comparison to Bitcoin's 10 minutes.  ‘While this matters little to traders, miners who use hardware to run Bitcoin's network cannot switch over to Litecoin. This keeps bigger mining conglomerates away from Litecoin because they cannot easily optimize their profits by swapping to another coin, contributing to a more decentralized experience. Litecoin also has bigger blocks, and more coins in circulation, making it more affordable and swift when transacting,’ Investopedia explained.  As explained above, Litecoin can transact a lot faster than Bitcoin, but there are also a number of other characteristics that investors need to know before trading. Litecoin can handle higher volumes of transactions because of the capability of transacting faster and if Bitcoin attempted to transact on the scale of its altcoin, a code update would be needed. However, Litecoin’s blocks would be larger, but with more ‘orphaned blocks'. The faster block time of litecoin reduces the risk of double spending attacks - this is theoretical in the case of both networks having the same hashing power.  Litecoin Technical Details: The transaction confirmation time taken for Litecoin is about 2.5 minutes on average (as compared to Bitcoin's 10 minutes). The Litecoin network is scheduled to cap at 84 million currency units.   Litecoin has inspired many other popular alternative currencies (eg. Dogecoin) because of its Scrypt hashing algorithm in order to prevent ASIC miners from mining those coins. However it is said that by the end of this year, Scrypt ASIC will enter the mass market.

Litecoin

Litecoin is buzzing as its community fiercely debates current price stability, with many emphasizing its robust support levels and long-term potential as "digital silver." Despite sentiment around perceived market manipulation, enthusiasts remain confident, highlighting future developments like MWEB privacy and Omnichain integration as key drivers. The widespread call to "buy the dip" underscores a strong conviction for significant future appreciation.

Webull Corp. engages in the provision of financial services. It offers trading, wealth management product distribution, market data and information, user community, and investor education. The company was founded by An Quan Wang in 2016 and is headquartered in St. Petersburg, FL.

Webull Corp. - Ordinary Shares - Class A

Webull Corp

Webull (BULL NASDAQ) is trending due to a fierce debate fueled by year-end tax loss selling and ongoing dilution from early SPAC investors, driving its price downward. The community is deeply split, with proponents viewing current levels as a significant "buy the dip" for a profitable, expanding fintech platform, while critics see a "falling knife" hindered by competition and supply overhang. Many anticipate a rebound in the coming period, drawing parallels to the early trajectories of other major brokerage platforms.

Redwire Corp. manufactures and supplies space equipment. It offers critical space solutions and reliability components for the next generation space economy with IP for solar power generation and in-space 3D printing and manufacturing. It assists its customers in solving challenges of future space missions. The company was founded in 2020 and is headquartered in Jacksonville, FL.

Redwire Corporation

Redwire Corp

Redwire (RDW) is trending following an eight-figure contract win for spacecraft docking systems and a reiterated "Buy" rating from analysts, fueling bullish sentiment around its role in the expanding space and defense sectors. The community is actively discussing the stock's high short interest, with many anticipating a potential short squeeze, while others remain cautious due to historical dilution concerns. This debate underscores RDW's perceived position as an undervalued player in the burgeoning space infrastructure market.

Corcept Therapeutics, Inc. is a commercial-stage pharmaceutical company, which engages in the business of discovering and developing pharmaceutical products and medications to treat severe endocrinologic, oncologic, metabolic, and neurologic disorders by modulating the effects of the hormone cortisol. The company was founded by David B. Singer and Joseph K. Belanoff on May 13, 1998 and is headquartered in Redwood City, CA.

Corcept Therapeutics Inc

Corcept Therapeutics (CORT) is experiencing high volatility as investors await an upcoming FDA decision for Relacorilant in Cushing's syndrome, alongside recent positive Phase 3 data for its ovarian cancer treatment. The community is sharply divided, with bullish investors anticipating significant market expansion and a potential short squeeze, while others express caution regarding valuation and regulatory risks. This dynamic biotech remains a focal point for those weighing transformative pipeline potential against immediate market pressures.

Eli Lilly & Co. engages in the discovery, development, manufacture, and sale of pharmaceutical products. The firm's products consist of diabetes, oncology, immunology, neuroscience, and other products and therapies. The company was founded by Eli Lilly in May 1876 and is headquartered in Indianapolis, IN.

Lilly(Eli) & Co

Eli Lilly is trending following strong Phase 3 data for its next-generation obesity drug, retatrutide, showing significant weight loss and pain reduction, alongside positive results for oral orforglipron in weight maintenance. This solidifies investor confidence in its dominant GLP-1 pipeline, even as the community discusses potential acquisitions and its ongoing competition in the rapidly expanding weight-loss market.

Ekso Bionics Holdings, Inc. engages in the provision of design, development, and sale of exoskeleton technology that currently has applications in healthcare and industrial markets. The company was founded on January 30, 2012 and is headquartered in San Rafael, CA.

Ekso Bionics Holdings Inc

Ekso Bionics is trending with exceptionally high trading volume following news of a proposed business combination with Applied Digital's cloud division to form the AI compute platform ChronoScale. The community is actively debating the implications of this AI-focused pivot, with discussions centered on its low float, potential for a short squeeze, and the significant gains already seen. While many anticipate further upside, some express caution regarding the long-term value for current shareholders due to potential dilution from the deal.

Interactive Brokers Group, Inc. is an investment holding company, which engages in broker or dealer and proprietary trading businesses. It offers custody and service accounts for hedge and mutual funds, exchange-traded funds, registered investment advisors, proprietary trading groups, introducing brokers, and individual investors. The company was founded by Thomas Pechy Peterffy in 1977 and is headquartered in Greenwich, CT.

Interactive Brokers Group Inc - Ordinary Shares - Class A

Interactive Brokers Group Inc 

Interactive Brokers is a trending topic following its S&P 500 inclusion and a strong Q3 earnings beat, which showcased robust client growth and trading activity. Despite numerous analyst upgrades and a bullish long-term outlook for its tech-led global expansion, community discussion reflects mixed reactions to the stock's immediate price performance, often contrasting it with competitors in the evolving brokerage landscape.

AGNC Investment Corp. engages in the operation of a real estate investment trust. The firm invests in residential mortgage pass-through securities and collateralized mortgage obligations for which the principal and interest payments are guaranteed by the United States government-sponsored enterprise or by the United States government agency. It also invests in other types of mortgage and mortgage-related securities, such as credit risk transfer securities and non-Agency residential and commercial mortgage-backed securities, where repayment of principal and interest is not guaranteed by the United States government-sponsored enterprise or by the United States Government agency, and other assets related to the housing, mortgage, or real estate markets. The company was founded on January 7, 2008 and is headquartered in Bethesda, MD.

AGNC Investment Corp

AGNC Investment Corp. is trending amid widespread anticipation of future interest rate cuts, a catalyst broadly perceived as bullish for the mREIT sector. The community is actively discussing the stock's consistent high monthly dividend and expresses confidence in its potential for both price appreciation and stable income, with many noting its perceived resilience in a volatile market despite some technical indicators suggesting overbought conditions.

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Instil Bio, Inc. (TIL) Is Up 4.07% in One Week: What You Should Know 

Wall Street Analysts Think Instil Bio (TIL) Could Surge 246.68%: Read This Before Placing a Bet

Are You Looking for a Top Momentum Pick? Why Instil Bio, Inc. (TIL) is a Great Choice

Summit Therapeutics Stock Nosedives on Mixed NSCLC Study Results

Instil Bio (TIL) Upgraded to Buy: What Does It Mean for the Stock?

Wall Street Analysts Believe Instil Bio (TIL) Could Rally 343.63%: Here's is How to Trade

<a href="https://stocktwits.com/symbol/TIL">Instil Bio’s stock</a> surged over 25% on Tuesday to levels last seen in early December after Jefferies upgraded the&nbsp;shares to ‘Buy’ from ‘Hold,’ with a new price target of $52 — more than double its current level.&nbsp;The upgrade reflects Jefferies’ confidence in the potential of Instil’s lead asset, SYN-2510, a novel PD-L1xVEGF bispecific antibody targeting multiple solid tumor cancers.Jefferies highlighted SYN-2510 as an “early mover” in the competitive cancer drug space, with significant upside expected from its planned clinical trials.&nbsp;A U.S. Phase 1b/2 study in non-small cell lung cancer (NSCLC) is scheduled to begin in the second half of 2025, focusing on driver gene mutation-negative non-squamous and squamous NSCLC patients.&nbsp;This trial will explore SYN-2510 in combination with chemotherapy, a promising strategy in frontline treatment settings.SYN-2510 is part of a global registrational strategy with China’s ImmuneOnco Biopharmaceuticals.&nbsp;In late 2024, ImmuneOnco started a Phase 1b/2 chemo combination study in China for frontline NSCLC. The collaboration aims to generate clinical proof-of-concept data in multiple solid tumors, with updates anticipated in early 2025.&nbsp;If successful, both companies may initiate joint randomized Phase 3 chemotherapy combination trials for NSCLC and triple-negative breast cancer (TNBC) in 2025.<figure class="image"><img style="aspect-ratio:1318/324;" src="https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/TIL_sentiment_and_message_volume_Jan_7_premarket_960267c1cd.png" alt="TIL sentiment and message volume Jan 7 premarket.png" width="1318" height="324"><figcaption>TIL sentiment and message volume Jan 7 as of 11:45 am ET | source: Stocktwits</figcaption></figure>Retail investors on Stocktwits reacted positively, pushing sentiment to ‘extremely bullish’ and boosting its message volume.&nbsp;<stembedurl>https://stocktwits.com/Blackcoupe369/message/599159968</stembedurl>Jefferies also noted that the stock is trading at cash value, which, combined with SYN-2510’s potential, suggests substantial growth opportunities.Instil reported $122.9 million in cash reserves as of September 2024, saying it was sufficient to fund its operations through at least 2026.&nbsp;The stock has climbed over 240% in the past year, driven by optimism around its innovative cancer therapies and impending trials, making it a standout player in the small-cap oncology space.For updates and corrections, email newsroom[at]stocktwits[dot]com.

Woman examining laboratory samples - stock photo | Image source: Getty Images

Instil Bio Stock Soars After Jefferies Upgrade On 'Early Mover' Cancer Drug Candidate: Retail Jubilant

Jefferies highlighted SYN-2510 as an “early mover” in the competitive cancer drug space, with significant upside expected from its planned clinical trials.

Equity

Shares of Instil Bio Inc. (TIL) skyrocketed over 60% on Friday, placing it among the top five gainers on U.S. stock exchanges and one of the top 20 trending tickers on Stocktwits, where message volume jumped 340%.The surge came after Baird raised its price target on the stock to $180, implying a 146% upside, while maintaining an ‘Outperform’ rating.Baird’s optimism is growing enthusiasm for Instil’s PD-L1xVEGF bispecific antibody, driven by positive data from peers like Akeso’s ivonescimab and Summit’s BNT327 in the same space.Analysts noted recent results and data released ahead of the European Society for Medical Oncology (ESMO) meeting have increased faith in this drug class for treating cancers like triple-negative breast, RCC, and head and neck.Baird expects continued momentum in this therapeutic area at ESMO, seeing further growth opportunities for Instil Bio. Despite the recent rally, the brokerage believes the stock remains undervalued, suggesting more room for gains.Baird’s price target hike follows H.C. Wainwright’s upgrade a day earlier, when it raised its price target from $25 to $40 with a ‘Buy’ rating. Wainwright expressed increased confidence in Instil’s SYN-2510, highlighting its strong antitumor synergy compared to traditional VEGF blockers and PD-L1 antibodies.Instil also announced a restructuring plan last week, including shutting down operations in Manchester, U.K., and laying off its remaining workforce there. The restructuring will cost up to $5.5 million, including $2.2 million in asset impairments and $2 million in severance.<figure class="image"><a href="https://stocktwits.com/symbol/TIL"><img style="aspect-ratio:1320/324;" src="https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/TIL_sentiment_and_message_volume_Sep_13_0d4fea2fed.png" alt="TIL sentiment and message volume Sep 13.png" width="1320" height="324"></a><figcaption>TIL sentiment and message volume Sep 13</figcaption></figure>Despite bullish analyst notes, retail investors remain wary. Sentiment on Stocktwits is ‘extremely bearish,’ with users questioning the sustainability of the stock’s rapid ascent.“$TIL 13$ last week, now 77$,” noted one user.<stembedurl>https://stocktwits.com/patbourque/message/585998096</stembedurl>Another warned, “$TIL from $9 to $70 in a few days!!! This is not going to go well next week.”<stembedurl>https://stocktwits.com/ProBulish/message/585995548</stembedurl>Adding to concerns, Instil’s fundamentals look shaky. The company reported zero revenue in the latest quarter, only $6.78 million in cash, and holds a $52.1 million mortgage construction loan on its Tarzana, California property, with an option to draw an additional $32.9 million.Instil Bio has soared 624% in the last month, and retail investors are exercising caution for now.Read next: <a href="https://stocktwits.com/news/markets/equity/mstr-stock-rises-on-bitcoin-buy-retail-bullish/c7z62Y5R5B">MicroStrategy Stock Surges On $1B Bitcoin Buy Amid Crypto Dip: Retail Bulls Rejoice</a> &nbsp;

Instil Bio Soars On Baird’s Price Target Boost: Retail Remains On Sidelines Amid Wild Surge

Despite a recent rally in Instil Bio shares, Baird believes the stock remains undervalued, suggesting more room for gains.

Instil Bio, Inc. is a clinical-stage biopharmaceutical company engaged in developing a cell therapy pipeline of autologous tumor infiltrating lymphocyte therapies for the treatment of patients with cancer. The company was founded in August 2018 and is headquartered in Dallas, TX.

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