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ImmunityBio, Inc. is a clinical stage immunotherapy company. It develops next generation therapies that drive immunogenic mechanisms for defeating cancers and infectious diseases. The company's immunotherapy platform activates both the innate and adaptive immune systems to create long term immunological memory. ImmunityBio was founded by Patrick Soon-Shiong in 2014 and is headquartered in San Diego, CA.

ImmunityBio Inc

ImmunityBio (IBRX) is soaring after Dr. Patrick Soon-Shiong's compelling presentation underscored Anktiva's cancer-curing potential, fueling fervent community discussion about an impending short squeeze and speculation regarding a supportive mention during the State of the Union address.

SoFi Technologies, Inc. is a financial service platform, which engages in the provision of student loan refinancing options to the private student loan market. It operates through the following segments: Lending, Technology Platform, and Financial Services. The Lending segment offers personal loans, student loans, home loan products, and related servicing activities. The Technology Platform segment focuses on technology products and solutions revenue. The Financial Services segment includes the SoFi Money product, SoFi Invest product, SoFi Credit Card product, SoFi Relay personal finance management product, and other financial services such as lead generation and content for other financial services institutions. The company was founded in 2011 and is headquartered in San Francisco, CA.

SoFi Technologies Inc

SoFi Technologies is trending following Jim Cramer's positive mention, which has sparked an intense community debate over whether it signals a genuine rebound or a 'Cramer pump,' as investors weigh the company's strong fundamentals against recent dilution and broader fintech sector volatility.

Lucid Group, Inc. manufactures electric vehicles. It designs, develops, and builds energy storage systems for electric vehicles and supplies automakers with the battery pack system needed to power hybrid, plug-in, and electric vehicles. The company was founded in December 2007 and is headquartered in Newark, CA.

Lucid Group Inc

Lucid Group is trending due to a mixed Q4 earnings report showing a revenue beat but significant losses and ongoing cash burn, compounded by recent workforce reductions and persistent dilution concerns. The community is sharply divided, with many questioning the company's long-term viability and leadership, while others highlight revenue growth and institutional investment as reasons for optimism.

Navitas Semiconductor Corp. engages in the development of ultra-efficient gallium nitride (GaN) semiconductors. Its GaN power ICs integrate GaN power with drive, control and protection to enable charging, power density, and energy savings for mobile, consumer, enterprise, eMobility and new energy markets. The company was founded by Daniel Kinzer, Nick Fichtenbaum, Gene Sheridan, and Jason Zhang on August 12, 2020 and is headquartered in Torrance, CA.

Navitas Semiconductor Corp

Navitas Semiconductor is trending due to its advanced GaN and SiC power platforms, which are considered crucial for next-gen AI data centers and grid infrastructure, leading to optimism about potential 'generational gains' from hyperscaler engagements. However, the community is actively debating the high valuation and the urgent need for definitive, revenue-generating contracts to materialize from these promising evaluations.

Workday, Inc. engages in the provision of development of enterprise cloud applications for finance and human resources. It delivers financial management, human capital management and analytics applications designed for companies, educational institutions, and government agencies. The company was founded by David A. Duffield and Aneel Bhusri in 2005 and is headquartered in Pleasanton, CA.

Workday Inc - Ordinary Shares - Class A

Workday Inc

Workday is trending after its latest earnings report, which, despite a beat on Q4 estimates, disappointed investors with weaker-than-expected subscription revenue guidance for the upcoming fiscal year. This fuels community speculation about decelerating growth in the broader enterprise software sector and the potential disruptive influence of AI on established SaaS models.

MercadoLibre, Inc. engages in the development of an online commerce platform with a focus on e-commerce and related services. It operates through the following geographical segments: Brazil, Argentina, Mexico, and Other Countries. The Other Countries segment refers to Chile, Colombia, Costa Rica, Dominican Republic, Ecuador, Panama, Peru, Bolivia, Honduras, Nicaragua, El Salvador, Guatemala, Paraguay, Uruguay, and the United States of America. Its products provide a mechanism for buying, selling, and paying as well as collecting, generating leads, and comparing lists through e-commerce transactions. The company was founded by Marcos Eduardo Galperin on October 15, 1999 and is headquartered in Montevideo, Uruguay.

MercadoLibre Inc

MercadoLibre is trending after its latest earnings report, which showed robust revenue growth but also compressed margins due to heavy investments and strong competition from rivals like Amazon in Latin America, fueling a sharp community debate between short-term profitability concerns and long-term market dominance.

Cava Group, Inc. is a holding company, which engages in the category-defining Mediterranean fast-casual restaurant brand, bringing together healthful food and bold, satisfying flavors at scale. It operates through the following segments: CAVA and CAVA Foods. The CAVA segment includes the operations of all company-owned CAVA restaurants. The CAVA Foods segment includes the production of dips and spreads used in CAVA restaurants as well as sales from the consumer-packaged goods (CPG) business. The company was founded by Brett Schulman, Ike Grigoropoulus, Dimitri Moshovitis, and Theodore Xenohristos in 2010 and is headquartered in Washington, DC.

Cava Group Inc

CAVA Group Inc

CAVA is trending after its Q4 earnings surpassed expectations, showcasing robust revenue growth and continued restaurant expansion, signaling strong performance despite a challenging economic environment. This has ignited a debate among investors, with bulls emphasizing its growth trajectory and appeal over competitors, while bears warn of its high valuation and margin pressures.

HP Inc. is an information technology company, which engages in the provision of personal computing and other access devices, imaging and printing products, and related technologies, solutions, and services. It operates through the following segments: Personal Systems, Printing, and Corporate Investments. The Personal Systems segment offers commercial and consumer desktop and notebook personal computers, workstations, thin clients, commercial tablets and mobility devices, retail point-of-sale systems, displays and other related accessories, software, support, and services for the commercial and consumer markets. The Printing segment provides consumer and commercial printer hardware, supplies, solutions and services, and scanning devices. The Corporate Investments segment includes HP Labs and certain business incubation projects. The company was founded by William R. Hewlett and David Packard in 1939 and is headquartered in Palo Alto, CA.

HP Inc

HP Inc. is trending as its recent Q1 earnings, which saw a revenue and EPS beat alongside an "AI PC boom," are overshadowed by a cautious Q2 and full-year profit outlook, with the community actively debating significant cost pressures from memory chip shortages and tariffs against the company's attractive valuation and dividend.

PayPal Holdings, Inc. engages in the development of technology platforms that enable digital payments and simplifies commerce experiences on behalf of merchants and consumers worldwide. Its solutions include PayPal, PayPal Credit, Braintree, Venmo, Xoom, and Paydiant products. The firm also enables consumers to exchange funds with merchants using funding sources, which include bank account, PayPal account balance, PayPal Credit account, credit, and debit card or other stored value products. It operates through United States and Other Countries geographical segments. The company was founded in December 1998 and is headquartered in San Jose, CA.

PayPal Holdings Inc

PayPal is a top trending stock as rumors of a potential acquisition, specifically from fintech rival Stripe, fuel widespread speculation among the community about an impending bidding war from other major tech and financial players eyeing the undervalued payments platform.

Axon Enterprise, Inc. engages in the development, manufacture, and sale of conducted electrical weapons for personal defense. It operates through the TASER segment and Software and Sensors segment. The TASER segment sells conducted electrical weapons, accessories, and other related products and services. The Software and Sensors segment includes devices, wearables, applications, cloud, and mobile products. The company was founded by Patrick W. Smith and Thomas P. Smith on September 7, 1993 and is headquartered in Scottsdale, AZ.

Axon Enterprise Inc

Axon is surging after delivering stellar earnings that significantly surpassed analyst expectations and providing a robust outlook, sparking widespread bullish sentiment and igniting a perceived short squeeze following a recent downturn. The community is noting CEO Rick Smith's emphasis on Axon's integrated hardware and software model, positioning it distinctively amid broader software market selloffs.

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<ul class="summary-bullets"><li>The therapy is to treat adults and children with Friedreich’s ataxia, a progressive neurodegenerative disorder.</li><li>Preliminary findings from the open-label study show that nomlabofusp increased FXN levels in patients’ skin to amounts observed in asymptomatic carriers.&nbsp;</li><li>FDA agreed that skin FXN could serve as a novel surrogate endpoint, supporting the planned Biologics License Application submission.</li></ul>Larimar Therapeutics, Inc. (LRMR) announced on Tuesday that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation (BTD) to its frataxin (FXN) protein replacement therapy, nomlabofusp.&nbsp;The therapy is to treat adults and children with Friedreich’s ataxia (FA), a progressive neurodegenerative disorder causing nervous system damage.<h2 class="st-heading-2">FDA Endorses Skin FXN As Surrogate Endpoint</h2>The FDA’s decision follows encouraging clinical data from Larimar’s ongoing open-label study and a recent Support for Clinical Trials Advancing Rare Disease Therapeutics (START) pilot program meeting.&nbsp;The agency also agreed that skin FXN could serve as a novel surrogate endpoint reasonably likely to predict clinical benefit, supporting the planned Biologics License Application (BLA) submission targeted for June 2026. The FDA additionally confirmed that the planned analyses, reference population, and clinical endpoints are aligned with BLA requirements.Following the FDA’s decision,&nbsp;<a href="https://stocktwits.com/symbol/LRMR">Larimar stock</a> traded over 30% higher in Tuesday’s premarket. On Stocktwits, retail sentiment around the stock jumped to ‘extremely bullish’ from ‘bearish’ territory the previous day. Message volume shifted to ‘extremely high’ from ‘high’ levels in 24 hours.&nbsp;<figure class="image"><img src="https://news.stocktwits-cdn.com/Screenshot_2026_02_24_084542_png_18caaedccf.webp" alt="LRMR’s Sentiment Meter and Message Volume as of 08:30 a.m. ET on Feb. 24, 2026 | Source: Stocktwits" width="932" height="105"><figcaption>LRMR’s Sentiment Meter and Message Volume as of 08:30 a.m. ET on Feb. 24, 2026 | Source: Stocktwits</figcaption></figure><h2 class="st-heading-2">Encouraging Clinical Data</h2>Preliminary findings from the open-label study show that nomlabofusp increased FXN levels in patients’ skin to amounts observed in asymptomatic carriers.&nbsp;Improvements were seen across four key clinical measures, the modified Friedreich Ataxia Rating Scale (mFARS), FARS-Activities of Daily Living (ADL), 9-Hole Peg Test (9-HPT), and Modified Fatigue Impact Scale (MFIS) after one year of treatment.&nbsp;The results suggest that nomlabofusp could slow or reverse FA progression compared with the natural disease course observed in the Friedrich’s Ataxia Clinical Outcomes Measure Study (FACOMS).LRMR stock declined by over 7% in the last 12 months.&nbsp;Also See:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/intuit-stock-rallies-pre-market-today-anthropic-connection/cZRvyjtR4C7">Intuit Stock Rallies Pre-Market Today And There’s An Anthropic Connection</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

A researcher works in the clinical-stage biopharmaceutical company Xencors new laboratory in Pasadena.

Why Did Larimar Therapeutics’ Stock Surge Over 30% Pre-Market Today? 

The FDA has granted Breakthrough Therapy Designation to Larimar’s frataxin protein replacement therapy, nomlabofusp.

Equity

The FDA has granted Breakthrough Therapy Designation to Larimar’s frataxin protein replacement therapy, nomlabofusp.


<ul class="summary-bullets"><li>Investigators noted that tumor shrinkage deepened over time, mirroring patterns previously observed with lifileucel in melanoma.</li><li>The data comes from a clinical trial testing lifileucel in patients with advanced undifferentiated pleomorphic sarcoma (UPS) or dedifferentiated liposarcoma (DDLPS).</li><li>The company plans to consult with the U.S. Food and Drug Administration regarding a potential expedited review process.</li></ul>Iovance Biotherapeutics Inc. (IOVA) on Tuesday reported encouraging early results from a pilot study evaluating its tumor-infiltrating lymphocyte therapy, lifileucel, in patients with aggressive soft tissue sarcomas who had exhausted prior treatments.&nbsp;The company said the findings support plans to pursue a potential speedy approval pathway in the United States.<h2 class="st-heading-2">Early Trial Results Show Strong Responses</h2>The data comes from a clinical trial led by Memorial Sloan Kettering Cancer Center and backed by Iovance, testing lifileucel in patients with advanced undifferentiated pleomorphic sarcoma (UPS) or dedifferentiated liposarcoma (DDLPS) whose disease had progressed after at least one systemic therapy.Among the first six patients whose outcomes could be evaluated, half experienced a confirmed tumor response. Investigators noted that tumor shrinkage deepened over time, mirroring patterns previously observed with lifileucel in melanoma and other solid tumors.&nbsp;The company also reported strong fourth-quarter (Q4) earnings led by $65 million in&nbsp; Amtagvi revenue. Following the update,&nbsp;<a href="https://stocktwits.com/symbol/IOVA">Iovance stock</a> traded over 5% higher in Tuesday’s premarket. On Stocktwits, retail sentiment around the stock shifted to ‘extremely bullish’ from ‘bullish’ territory the previous day amid ‘high’ message volume levels.&nbsp;<h2 class="st-heading-2">Next Steps Toward Registration</h2>Based on the initial findings, Iovance said it intends to launch a single-arm registrational trial in the second quarter of 2026 for second-line advanced UPS and DDLPS. The company plans to consult with the U.S. Food and Drug Administration regarding a potential expedited review process.<blockquote>“In the first clinical trial of a TIL cell therapy in UPS and DDLPS, one-time treatment with lifileucel demonstrated compelling and unprecedented response rates with the potential to address a significant unmet need in patients who are refractory to frontline standard of care.”-Lauren Baker Banks, Sarcoma Medical Oncologist, Memorial Sloan Kettering Cancer Center</blockquote>In Q4, total product revenue was about $87 million, marking roughly 30% growth year-over-year. Gross margin for the quarter was approximately 50%, driven by improved operations and ongoing cost control efforts.IOVA stock has declined by over 47% in the last 12 months.&nbsp;Also See:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/vir-stock-surges-pre-market-today-analysts-cheer-strong-cancer-data-astellas-partnership/cZRvUqdR4C5">VIR Stock Surges 60% Pre-Market Today – Analysts Cheer Strong Cancer Data, Astellas Partnership</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, the Iovance Biotherapeutics company logo is seen displayed on a smartphone screen. (Photo Illustration by Piotr Swat/SOPA Images/LightRocket via Getty Images)

Why Did IOVA Stock Gain Pre-Market Today? 

The company announced encouraging early results from a pilot study evaluating its tumor-infiltrating lymphocyte therapy, lifileucel and reported strong fourth-quarter earnings. 

<ul class="summary-bullets"><li>Palvella said the study met its key secondary endpoint and all four additional secondary endpoints.</li><li>In the Phase 3 SELVA study, QTORIN rapamycin was generally well tolerated.&nbsp;</li><li>The company plans to submit an NDA to the U.S. FDA in the second half of 2026.</li></ul>Shares of Palvella Therapeutics Inc (PVLA) jumped nearly 37% on Tuesday, after the company reported positive topline results from its Phase 3 SELVA study, potentially paving the way for a FDA submission.&nbsp;The company said its lead candidate, QTORIN 3.9% rapamycin anhydrous gel, met its primary endpoint, showing a statistically significant improvement on the Microcystic Lymphatic Malformation Investigator Global Assessment scale.&nbsp;The study also met its key secondary endpoint and all four additional secondary endpoints, each demonstrating statistical significance in patients with microcystic lymphatic malformations (MLM), a rare vascular condition. MLM is a benign, fluid-filled cyst that can form under the skin, often on the neck or the head.<h2 class="st-heading-2">QTORIN Rapamycin Was Well Tolerated</h2>In the Phase 3 SELVA study, QTORIN rapamycin was generally well tolerated. Of the 50 patients who started treatment, 70% reported side effects, most of which were mild or moderate. Four serious adverse events were reported, but investigators said they were not related to the drug. The most common treatment-related issues were mild skin reactions at the application site.88% of the patients completed the 24-week study. Nearly all eligible participants chose to continue treatment in the extension phase.Based on these results, the company plans to submit a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) in the second half of 2026, with potential U.S. approval expected in the first half of 2027, the firm added.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>Retail sentiment on Stocktwits flipped to ‘extremely bullish’ following the update, from ‘neutral’ a day earlier. Message volume on the platform was ‘extremely high’.<img src="https://news.stocktwits-cdn.com/PVLA_jpg_d1bfdadf88.webp" alt="PVLA.jpg">Year-to-date, the stock has gained around 16%&nbsp;For updates and corrections, email newsroom[at]stocktwits[dot]com.

Why Did PVLA Stock Surge 37% Today?

The biotech company reported statistically significant Phase 3 data for QTORIN gel.

PVLA Stock Soars On Strong Phase 3 Results For Rare Vascular Disorder Treatment 

<ul class="summary-bullets"><li>Canaccord also lowered its price objective, cutting it to $80 from $105, while keeping a ‘Buy’ rating in place.</li><li>Analyst Catherine Ramsey Schulte said Baird updated its financial model to reflect the trial outcome but did not downgrade the stock.</li><li>Canaccord said it continues to view the broader data set from the U.K. initiative constructively.</li></ul>Grail Inc. (GRAL) stock remains in the spotlight after two Wall Street firms trimmed their price targets following disappointing data from a key U.K. study, even as both maintained bullish ratings.On Thursday, the company announced that its study of the Galleri blood test, used for yearly multi-cancer screening in England’s National Health Service, failed to achieve its main goal.<a href="https://stocktwits.com/symbol/GRAL">Grail stock</a> traded over 42% lower in Friday’s premarket. However, on Stocktwits, retail sentiment around the stock changed to ‘extremely bullish’ from ‘bullish’ territory the previous day amid ‘extremely high’ message volume levels.&nbsp;<figure class="image"><img src="https://news.stocktwits-cdn.com/Screenshot_2026_02_20_072336_png_b625b032ea.webp" alt="GRAL’s Sentiment Meter and Message Volume as of 07:00 a.m. ET on Feb. 20, 2026 | Source: Stocktwits" width="933" height="104"></figure><h2 class="st-heading-2">Target Cuts Follow Trial Update</h2>The outcome prompted analysts to revisit their financial assumptions and adjust expectations for the blood-based cancer screening test developer. Baird analyst Catherine Ramsey Schulte slashed the price target on Grail to $82 from $113 while reiterating an ‘Outperform’ rating, according to TheFly.&nbsp;Canaccord also lowered its price objective, cutting it to $80 from $105, while keeping a ‘Buy’ rating in place.<h2 class="st-heading-2">Canaccord Sees Market Overreaction</h2>Schulte said Baird updated its financial model to reflect the trial outcome but stopped short of downgrading the stock, signaling continued confidence in Grail’s long-term commercial prospects despite the setback.Canaccord acknowledged disappointment over the topline findings from the NHS-Galleri study and conceded that the regulatory and commercial path ahead may now appear less predictable.Still, the firm said that the steep after-hours drop, which approached 50%, is an ‘overreaction’. Canaccord said it continues to view the broader data set from the U.K. initiative constructively, even though the study did not achieve its principal goal.GRAL stock has gained over 112% in the last 12 months.&nbsp;Also See:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/why-did-kosmos-energy-stock-surge-pre-market-today/cZRNcfoR4xe">Why Did Kosmos Energy Stock Surge 10% Pre-Market Today?</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

The NYSE app is seen in the app store in this illustration photo taken in Warsaw, Poland.

Why Is GRAL Stock Down Today? Analysts Lower Targets After UK Trial Setback But Call Selloff Overdone

Baird analyst Catherine Ramsey Schulte slashed the price target on Grail to $82 from $113 while reiterating an ‘Outperform’ rating.

<ul class="summary-bullets"><li>Merck is currently seeking to fortify its drug portfolio before its blockbuster cancer therapy Keytruda begins to lose patent protection in 2028.</li><li>While there were reports of Merck looking to acquire cancer drugmaker Revolution Medicines in January for about $30 billion, a deal didn’t materialize.</li><li>MoonLake Therapeutics, headquartered in Switzerland, is developing its investigational therapy sonelokimab for the treatment of inflammatory diseases.</li></ul>Shares of MoonLake Immunotherapeutics (MLTX) garnered retail attention on Tuesday amid buyout speculation.On Stocktwits, a retail investor voiced optimism for either a buyout announcement or positive news from the U.S. Food and Drug Administration for the company this week.<stembedurl>https://www.stocktwits.com/Warren_8/message/645090086</stembedurl>Another user, however, said that MoonLake must increase its share price from current levels if it wants to be acquired.<stembedurl>https://www.stocktwits.com/Newcar/message/645134185</stembedurl>Some users also highlighted a potential takeover by pharma major Merck for MoonLake.<stembedurl>https://www.stocktwits.com/Bigpapa46/message/645006814</stembedurl>On Stocktwits, overall retail sentiment around MLTX improved from ‘extremely bearish’ to ‘bearish’ territory over the past 24 hours, while message volume remained at ‘low’ levels.Shares of the company closed 11% higher in the regular trading session. &nbsp;<h2 class="st-heading-2">Is Merck Looking To Acquire Companies?</h2>Merck is currently seeking to fortify its drug portfolio before its blockbuster cancer therapy Keytruda begins to lose patent protection in 2028. Keytruda generated approximately $29.5 billion in global sales for the full year 2024, accounting for about 46% of the company’s overall worldwide sales.The company entered into a deal to acquire Cidara Therapeutics for about $9.2 billion in November. It also agreed to buy respiratory drug developer Verona Pharma for $10 billion in July as part of a broader effort to maintain revenue momentum.While there were reports of Merck looking to acquire cancer drugmaker Revolution Medicines in January for about $30 billion, a deal didn’t materialize as the two companies failed to come to an agreement on price, The Wall Street Journal reported.<h2 class="st-heading-2">MoonLake’s Portfolio</h2>MoonLake Therapeutics, headquartered in Switzerland, is developing its investigational therapy sonelokimab for the treatment of inflammatory diseases such as hidradenitis suppurativa, psoriatic arthritis, axial spondyloarthritis and palmoplantar pustulosis.Earlier this month, the FDA granted Fast Track designation to sonelokimab in moderate-to-severe palmoplantar pustulosis. The company is also eyeing making an application to the FDA for approval of sonelokimab in hidradenitis suppurativa in the second half of 2026.The company is now slated to hold an investor day event on Feb. 23, 2026.<a href="https://stocktwits.com/symbol/MLTX">MLTX stock</a> has dropped 59% this year.&nbsp;Read More: <a href="https://stocktwits.com/news-articles/markets/equity/help-stock-rallies-after-experimental-depression-drug-reduces-symptoms-in-study/cZRWDUOR4HP">HELP Stock Rallies After Experimental Depression Drug Reduces Symptoms In Study: Retail Thinks Its ‘Time To Buy More’</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, the MoonLake Immunotherapeutics (Moon Lake) logo is seen displayed on a smartphone screen. (Photo Illustration by Thomas Fuller/SOPA Images/LightRocket via Getty Images)

MLTX Stock Gains As Retail Eyes Buyout From Big Pharma, Upcoming Investor Day Event

Some Stocktwits users voiced optimism for the inflammation-drug maker getting acquired by pharma giant Merck. 

<ul class="summary-bullets"><li>ImmunityBio began discussions with SFDA to expand the use of ANKTIVA in combination with checkpoint inhibitors for multiple tumor types.</li><li>ANKTIVA is already approved in Saudi Arabia for two indications: BCG-unresponsive non-muscle invasive bladder cancer and metastatic lung cancer.</li><li>Earlier this year, ImmunityBio established a wholly owned local subsidiary to support regulatory filings, commercialization, and clinical development.</li></ul>Shares of ImmunityBio, Inc. (IBRX) climbed about 6% in premarket trading on Tuesday after the Saudi Food and Drug Authority (SFDA) encouraged the company to submit a regulatory filing for its recombinant Bacillus Calmette-Guérin (rBCG), a move aimed at expanding treatment access in Saudi Arabia and easing the ongoing global shortage.&nbsp;The company said it expects to file the submission within the next few weeks. BCG is an immunotherapy drug used to treat early-stage bladder cancer.&nbsp;<h2 class="st-heading-2">Expanding ANKTIVA Across Tumor Types</h2>The company also began discussions with the SFDA to broaden the use of ANKTIVA in combination with checkpoint inhibitors for multiple tumor types beyond metastatic non-small cell lung cancer. ANKTIVA is an Interleukin-15 (IL-15) receptor agonist. IL-15 is an immune protein that helps develop and activate key cells that destroy cancer cells.The therapy <a href="https://stocktwits.com/news-articles/markets/equity/why-did-ibrx-stock-gain-retail-attention-today/cmULjP5R4eA">received</a> accelerated approval in Saudi Arabia in January 2026 for patients whose disease progressed after standard treatments. Data from the QUILT-3.055 Phase 2b trial showed the combination restored checkpoint inhibitor activity across cancers such as melanoma, renal, gastric, and cervical tumors, with a median overall survival of 14.1 months in relapsed lung cancer patients.<h2 class="st-heading-2">Strengthening Regional Presence</h2>ANKTIVA is already approved in Saudi Arabia for two indications: BCG-unresponsive non-muscle invasive bladder cancer and metastatic lung cancer. ImmunityBio has also established a wholly owned local subsidiary to support regulatory filings, commercialization, and clinical development across the Middle East and North Africa.“Saudi Arabia was the first country in the world to grant approval for ANKTIVA in metastatic lung cancer. The QUILT-3.055 basket trial provides data that ANKTIVA rescues checkpoint activity across multiple tumor types, and we look forward to working with the SFDA to extend this approach to additional malignancies,” said Patrick Soon-Shiong, Executive Chairman and Global Chief Scientific and Medical Officer of ImmunityBio.Soon-Shiong <a href="https://stocktwits.com/news-articles/markets/equity/anktiva-vs-keytruda-immunity-bio-exec-chair-slams-fda-for-double-standards-in-approvals/cZRW7FaR4M8">recently criticized</a> the U.S. Food and Drug Administration (FDA), claiming the agency accelerated approval for Merck &amp; Co.’s cancer therapy Keytruda while limiting ANKTIVA to a single bladder cancer indication.Speaking on The Roger Stone Show, Soon-Shiong argued that regulatory delays are creating a bottleneck that could restrict patient access to a treatment he believes has significant life-saving potential.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>Despite the premarket movement, retail sentiment for <a href="https://stocktwits.com/symbol/IBRX">IBRX</a> on Stocktwits remained ‘bearish’ over the past 24 hours.<img src="https://news.stocktwits-cdn.com/IBRX_jpg_242ebbcbd6.webp" alt="IBRX.jpg">However, chatter was more bullish, with one user looking to buy more shares because the ‘price is attractive.’<stembedurl>https://stocktwits.com/Deggie/message/645099523</stembedurl>Another user expects a strong rebound following a slight dip at market open.<stembedurl>https://stocktwits.com/Wowsuchboolish/message/645100328</stembedurl>The stock has seen strong buying interest so far this year, gaining more than 210%.Read also: <a href="https://stocktwits.com/news-articles/markets/equity/gold-silver-prices-fall-peter-schiff-buy-the-dips/cZRWkdSR4ua">Peter Schiff&nbsp;Signals ‘Buy The Dips’ As Gold, Silver Extend Fall – PAAS, AG, HL Stocks Down Over 3.5% Premarket</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, an ImmunityBio company logo is seen displayed on a smartphone screen. (Photo Illustration by Piotr Swat/SOPA Images/LightRocket via Getty Images)

IBRX Stock Jumps 6% Pre-Market On BCG Update In Saudi Arabia – Retail Says Share Price Is ‘Attractive’

The Saudi Food and Drug Authority encouraged the company to submit a regulatory filing for its recombinant Bacillus Calmette-Guérin, which the company expects to submit within weeks.

<ul class="summary-bullets"><li>After the adjustment, Intensity Therapeutics stock will begin trading on February 19, retaining the ticker symbol INTS.</li><li>The stock consolidation will reduce the total shares outstanding from approximately 63.3 million to about 2.53 million.</li><li>In January, the company said it raised more than $20 million in 2025, extending its cash runway into the second quarter of 2027.&nbsp;</li></ul>Intensity Therapeutics, Inc. (INTS) on Friday announced a 1-for-25 reverse stock split approved by its board and shareholders, aiming to boost the per-share price of its common stock to meet Nasdaq’s minimum listing requirements.The reverse split, scheduled to take effect at 4:01 p.m. ET on February 18, will consolidate every 25 existing shares into a single new share.<h2 class="st-heading-2">Changes After The Reverse Split</h2>After the adjustment, Intensity Therapeutics stock will begin trading on February 19, under a new CUSIP number 45828J 202 while retaining the ticker symbol INTS.Following the announcement,&nbsp;<a href="https://stocktwits.com/symbol/INTS">Intensity Therapeutics stock&nbsp;</a>traded 25% lower on Friday morning.&nbsp;On Stocktwits, retail sentiment around the stock remained in ‘bullish’ territory amid ‘high’ message volume levels.&nbsp;Intensity is a late-stage biotech company developing its own cancer treatments. It uses a special drug-linking technology to create therapies that aim to destroy tumors and help the immune system better detect cancer.<h2 class="st-heading-2">Impact on Shareholders</h2>The stock consolidation will reduce the total shares outstanding from approximately 63.3 million to about 2.53 million. No fractional shares will be issued; instead, shareholders entitled to a fraction will receive cash payments based on the adjusted closing price on February 18.Alongside the split, the company will make proportional changes to stock options, warrants, convertible securities, and shares issued under its stock incentive programs. The total number of authorized shares will remain unchanged.In January, the company outlined its 2025 achievements and mapped out priorities for 2026 as it advances INT230-6, its lead cancer therapy designed to destroy tumors and stimulate immune response. Intensity raised more than $20 million in 2025, extending its cash runway into the second quarter of 2027.&nbsp;INTS stock has declined by over 87% in the last 12 months.&nbsp;Also See:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/tesla-stock-slips-premarket-ev-headwinds-mount-wall-street-sees-upside-physical-ai-future/cZR5NHfR4sm">Tesla Stock Slips Premarket As EV Headwinds Mount — But One Wall Street Firm Sees Over 30% Upside On A ‘Physical AI’ Future</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

ProKidney (PROK) is developing rilparencel, an autologous cellular therapy aimed at slowing kidney function decline in patients with chronic kidney disease/ Photo credit: Getty Images

Why Did INTS Stock Plummet 25% Today? 

Intensity Therapeutics announced a 1-for-25 reverse stock split, consolidating every 25 existing shares into a single new share.

<ul class="summary-bullets"><li>The company stated that the global REZOLVE-AD Phase 2b study included 393 patients with moderate-to-severe atopic dermatitis.</li><li>Nektar stated that patients receiving monthly and quarterly dosing regimens resulted in sustained disease control for EASI-75, EASI-90, and other indicators.</li><li>The company also noted that it observed an increase in patients who achieved EASI-100 in the 24 micrograms per kilogram dosing regimens in the monthly and quarterly time periods.</li></ul>Nektar Therapeutics Inc. (NKTR) shares rose more than 42% in Tuesday’s opening trade after the company reported positive results from its long-term atopic dermatitis trial.Nektar announced positive results from the 36-week blinded maintenance period of the 52-week REZOLVE-AD study of its experimental drug, rezpegaldesleukin.Retail sentiment around&nbsp;<a href="https://stocktwits.com/symbol/NKTR">Nektar Therapeutics</a> trended in the ‘extremely bullish’ territory at the time of writing, with message volumes at ‘extremely high’ levels. The NKTR stock was among the top ten trending tickers on the platform.<h2 class="st-heading-2">Nektar’s Findings In The Trial</h2>The company stated that the global REZOLVE-AD Phase 2b study included 393 patients with moderate-to-severe atopic dermatitis.Nektar stated that patients receiving monthly and quarterly dosing regimens achieved sustained disease control as measured by EASI-75, EASI-90, the validated Investigator Global Assessment of Atopic Dermatitis (vIGA-AD) response, and the Itch Numerical Rating Scale (NRS) response.The company also noted an increase in patients achieving EASI-100 on the 24 micrograms per kilogram dosing regimens during the monthly and quarterly periods.EASI refers to the Eczema Area and Severity Index. It quantifies the severity and extent of eczema symptoms across body regions. EASI-75 points to a greater than or equal to 75% improvement from baseline, while EASI-90 refers to a 90% or more improvement. Similarly, EASI 100 denotes a 100% improvement over baseline.<h2 class="st-heading-2">Retail Gives A Thumbs Up</h2>One bullish user observed that “patience does pay off,” while adding that they are not selling the stock.<stembedurl>https://stocktwits.com/aristocks/message/644554531</stembedurl>Another user stated that there is nothing to “even remotely” criticize Nektar for, following the announcement of the trial results.<stembedurl>https://stocktwits.com/clarksonhockey/message/644552638</stembedurl><a href="https://stocktwits.com/symbol/NKTR">NKTR stock</a> is up 24% year-to-date and 204% over the past 12 months.Also See:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/why-is-fisv-stock-falling-today/cZbU3sOR4Yp">Why Is FISV Stock Falling Today?</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

Low-angle view of a logo on a facade at the headquarters of Nektar Therapeutics, on October 29, 2018. (Photo by Smith Collection/Gado/Getty Images)

NKTR Stock Soars After Nektar Reports Positive Atopic Dermatitis Trial Results

Nektar announced positive results from the 36-week blinded maintenance period of the 52-week REZOLVE-AD study of its experimental drug, rezpegaldesleukin.

<ul class="summary-bullets"><li>Oscar Health’s Q4 total revenue came in at $2.81 billion, below estimates of $3.12 billion, according to Fiscal.ai data.</li><li>The company’s medical loss ratio was 95.1% compared to 88.1% last year.</li><li>Oscar Health expects to return to profitability in 2026, eyeing earnings from operations in the range of $250 million to $450 million.</li></ul>Oscar Health (OSCR) shares traded nearly 5% higher on Tuesday morning after the company projected fiscal 2026 revenue well above the FY2025 level reported alongside its fourth-quarter results.<h2 class="st-heading-2">Q4 Snapshot</h2>The company forecast fiscal 2026 revenue between $18.7 billion and $19 billion, compared with $11.70 billion in fiscal 2025. However, the health insurer’s fourth-quarter (Q4) total revenue came in at $2.81 billion, significantly below the Street estimates of $3.12 billion, according to Fiscal.ai data. Oscar also reported a loss of $1.24 per share, wider than the estimates of a loss of $0.92 per share.The company’s medical loss ratio (MLR) was 95.1%, meaning 95.1% of total premiums paid by policyholders went toward claims, with the remaining 4.9% retained by the insurer. It was 88.1% last year.As of Feb. 1, 2026, Oscar served about 3.4 million members.<h2 class="st-heading-2">Firm Eyes Profitability In 2026</h2>CFO Scott Blackley said in a call with analysts that the firm expects to meaningfully improve financial performance and return to profitability in 2026.“We expect earnings from operations to be in the range of $250 million to $450 million, a significant improvement of nearly $750 million year-over-year, implying an operating margin of approximately 1.9% at the midpoint. Adjusted EBITDA is expected to be approximately $115 million higher than earnings from operations,” Blackley said.Oscar Health posted a net loss in five of the last six quarters, according to Koyfin data.On February 6, the company secured a $475 million, three-year revolving credit facility, which Blackley said will provide flexibility to support long-term growth and expand adoption in the individual market.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>Retail sentiment on Stocktwits flipped to ‘extremely bullish’ from ‘bearish’ a day back, amid ‘extremely high’ message volumes. <a href="https://stocktwits.com/symbol/OSCR">OSCR</a> was among the top trending tickers at the time of writing.<img src="https://news.stocktwits-cdn.com/OSCR_jpg_b3b9347c93.webp" alt="OSCR.jpg">One user was bullish about the guidance, expecting the stock price to double over the coming weeks.<stembedurl>https://stocktwits.com/eatsleeptrades/message/644543099</stembedurl>Another user highlighted that they are adding to their position.<stembedurl>https://stocktwits.com/Buyhighsellatlow/message/644556418</stembedurl>Year-to-date, the stock has declined around 10%Read also: <a href="https://stocktwits.com/news-articles/markets/equity/sidu-stock-gains-pre-market-partnership-with-simera/cZbUI6iR4YC">SIDU Stock Gained 5% In Pre-Market Today – What Is The Deal With Simera Sense About?</a>For updates and corrections, email newsroom[at]stocktwits[dot]com

In this photo illustration, the logo of Oscar Health, Inc. is displayed on a smartphone screen on May 04, 2025, in Chongqing, China.  (Photo illustration by Cheng Xin/Getty Images)

Why Is OSCR Stock Rising Today? 

The company expects fiscal 2026 revenue to be between $18.7 billion and $19 billion, compared with $11.70 billion in fiscal 2025.

Should You Invest in the Vanguard Health Care ETF (VHT)?

Vanguard Group, Inc. - Vanguard Health Care ETF

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Miss EPS and revenue

Ahead of earnings, sentiment is split between blowout AI growth and concerns around macro pressure, positioning, and post-ER volatility. How do you see it playing out?

Current Price	$291.93
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52-Week Low	$234.11
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