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Applied Digital Corp. is a technology company, which engages in the provision of development and operation of data centers which provide computing power. It operates through the Data Center Hosting Business and HPC Hosting Business segments. The Data Center Hosting Business segment provides energized infrastructure services to crypto mining customers. The HPC Hosting Business segment focuses on the designing, constructing, and operating data centers tailored to support high power density applications like HPC and AI. The company was founded by Wesley Carl Cummins and Jason Zhang in May 2001 and is headquartered in Dallas, TX.

Applied Digital Corporation

APLD is trending after a strong earnings report and news of a massive AI lease deal, positioning the company as a key player in AI infrastructure. The community is excited about the potential for a short squeeze and analysts raising price targets, while also debating entry points and long-term prospects. Bullish sentiment is fueled by the company's growth in the AI data center space, with some comparing it to other high-flying stocks in the sector.

SEALSQ Corp. is a holding company, which engages in the security of microcontrollers. It operates through the following geographical segments: North America, Europe, Middle East, Africa, Asia Pacific, and Latin America. It focuses on authentication process, digital certification, and covering individual patents of semiconductors. The company was founded on April 1, 2022 and is headquartered in Cointrin, Switzerland.

SEALSQ Corp

SEALSQ ($LAES) is surging due to a strategic partnership focused on developing quantum-resistant chips for U.S. defense applications, fueling speculation about lucrative government contracts. The community is buzzing about the company's growth potential and comparing it to other players in the quantum computing space, with some investors believing LAES is undervalued and predicting a significant climb.

TeraWulf, Inc. owns and operates fully integrated environmentally clean bitcoin mining facilities in the United States. TeraWulf will generate domestically produced bitcoin powered by nuclear, hydro and solar energy. The company was founded by Paul Prager and Nazar Khan on February 8, 2021 and is headquartered in Easton, MD.

TeraWulf Inc

TeraWulf is trending due to its potential for a short squeeze, driven by high short interest and growing optimism around its shift towards AI and high-performance computing. Community members highlight Google's backing and the company's advantageous position in the data center sector. Discussions also focus on TeraWulf's potential to catch up with sector peers like CIFR and IREN.

CleanSpark, Inc. is a bitcoin mining technology company, which engages in the management of data centers. Its operations include College Park, Norcross, Washington, Sandersville, Dalton, and Massena. The company was founded by S. Matthew Schultz and Bryan Huber on October 15, 1987 and is headquartered in Henderson, NV.

Cleanspark Inc

Cleanspark is trending as the community discusses its potential for significant growth, drawing comparisons to IREN's valuation and anticipating news related to AI/HPC ventures. Bullish sentiment is fueled by the company's strong Bitcoin holdings, infrastructure ownership, and a recent mining update, with many expecting a run to higher price targets. Additionally, some are speculating on government involvement and the potential for a short squeeze.

RAGE GUY (RAGE) is a cryptocurrency inspired by the Rage Guy meme, one of the earliest and most recognizable characters from internet rage comics. The project captures the cultural legacy of early meme history and brings it onto the blockchain in tokenized form. It is designed as a community-driven digital asset that celebrates internet culture, nostalgia, and the role memes play in shaping online communities.

Rage Guy

RAGE CRYPTO is gaining traction as community members express excitement, referencing an imminent listing on Moonshot and calling for others to "RAGE" harder. Fueling the hype, some are alluding to potential breakouts and increased liquidity, while others point to the project's roots in OG internet meme culture. The community's focus remains on strong community building and promoting the idea of everyone making it.

One and one Green Technologies. Inc - Ordinary Shares - Class A

YDDL is trending due to its recent IPO and subsequent volatile price action, with the stock experiencing significant gains and drops. The community is actively discussing its low float, high insider ownership, and potential for both further gains and significant losses, with some expressing concerns about it being a pump and dump. Some traders are also looking at other AI and Green Tech names like $APLD and $HIVE.

GSR III Acquisition Corp engages in the merger, share exchange, asset acquisition, share purchase or reorganization with one or more businesses. The company was founded on May 10, 2023 and is headquartered in Austin, Texas.

GSR III Acquisition Corp. - Ordinary Shares- Class A

GSR III Acquisition Corp. Ordinary Shares

GSRT is trending due to the imminent ticker change to NKLR following its merger with Terra Innovatum, a micro-modular nuclear reactor developer; the change is expected to occur soon. Community members are excited about the potential, drawing comparisons to OKLO and highlighting the growing demand for nuclear energy. Discussions also include the stock's valuation relative to its peers and expectations for increased volume and volatility post-ticker change.

MARA Holdings, Inc. is a digital asset technology company, which engages in mining cryptocurrencies with a focus on the Bitcoin ecosystem. It also deals with owning and operating bitcoin mining facilities or data centers, selling proprietary software or technology to third parties operating in the Bitcoin ecosystem, offering advisory and consulting services to support Bitcoin mining ventures in domestic and international jurisdictions, and generating electricity from renewable energy resources or methane gas capture to power Bitcoin mining projects. The company was founded on February 23, 2010 and is headquartered in Hallandale Beach, FL.

MARA Holdings Inc.

Marathon Digital Holdings Inc

MARA is trending as traders discuss its potential for a short squeeze, given its high short interest and Bitcoin's recent price movements. Community members are debating the company's management and future prospects in AI, with some expressing frustration over its performance compared to other miners like CLSK and IREN, while others highlight its large Bitcoin holdings and potential for growth.

SU Group Holdings Ltd. engages in the provision of security-related engineering services, and security guarding and screening services. It operates through the Security-Related Engineering Services and Security Guarding and Screening Services segments. The company was founded by Ming Chan in 1998 and is headquartered in Hong Kong.

SU Group Holdings Ltd. - Ordinary Shares - Class A

SU Group Holdings Ltd.

SUGP is trending due to a recently announced record-breaking hospital contract, sparking significant community interest and a volatile trading environment. Community members are actively discussing the stock's potential for a multi-day run, citing its low float and strong fundamentals, while also debating the likelihood of further price manipulation. The stock's association with other Hong Kong plays is also contributing to the buzz.

The 401jk (just kidding) meme is a satirical punch in the gut in the face of the concept of retirement and also the 401k. The 401k total holdings are valued at around $12 trillion USD and it is the most popular retirement savings plan in the US. As time passes forevermore true retirement, or as we like to call it real freedom will only become much harder and harder for people to attain.  Through meme fueled laser focus and cyperphunk ideology the 401jK meme retirement fund token and community aim to point out the absurdities of how rigged our current system is, and how only insiders and those with power are starting the benefit from the increased centralization of cryptocurrency.........while also aiming to flip the $12 trillion USD 401k system to achieve freedom before our backs and knees are breaking.

401jK

401JK is trending as community members rally behind its narrative of disrupting traditional retirement systems. The coin's ticker and meme-driven approach are generating excitement, with many believing it has the potential for significant growth. Discussions revolve around its strong community, chart consolidation, and the idea of achieving early retirement.

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4 Reasons to Buy Pharma ETFs Now for a Healthy Portfolio

Pharma's Trump-Pfizer boost sparks momentum, making ETFs PPH, IHE, PJP & XPH attractive for defensive, undervalued growth plays.

Trump Slams 100% Tariff on Imported Drugs: Pharma ETFs Take a Hit

Trump's 100% tariff on imported drugs jolts markets, slamming pharma giants and dragging ETFs like XPH, FTXH, IHE, and PPH lower.     

White House Press Secretary Karoline Leavitt said on Thursday that President Donald Trump is set to send out letters to 17 pharmaceutical company CEOs in the U.S., including Eli Lilly (LLY), giving them 60 days to address the global pricing disparity of drugs.“Other nations have been free-loading on U.S. innovation for far too long, and it is time they pay their fair share,” said Leavitt, reading out one of the letters, addressed to Eli Lilly CEO David A. Ricks.<a href="http://stocktwits.com/symbol/LLY">Eli Lilly’s stock</a> dipped more than 1% in afternoon trade after the news broke. On Stocktwits, retail sentiment around the pharmaceutical giant remained in ‘bullish’ territory over the past day.Other pharma stocks also took a hit. Moderna (MRNA) extended its downtrend, dipping nearly 7%, AstraZeneca (AZN) slipped more than 3% and Pfizer (PFE) was down over 1%.&nbsp;The warning comes after Trump signed an executive order delivering ‘most favored nation’ prescription drug pricing for U.S. patients in May.The letter alleges that most of the proposals that the Trump administration has received to resolve the issue of drug pricing promised “more of the same, shifting blame, and requesting policy changes that would result in billions of dollars in handouts to the industry.”It outlines that drug makers have 60 days to achieve the following goals:- Extend the ‘most favored nation’ pricing to Medicaid- Guarantee ‘most favored nation’ pricing for newly launched drugs- Return increased revenues abroad to American patients and taxpayers- Provided for direct purchasing at ‘most favored nation’ pricing“But if you refuse to step up, we will deploy every tool in our arsenal to protect American families from continued abusive drug pricing practices,” warned the letter, adding that the Trump administration, U.S. Health Secretary Robert Kennedy Jr. and Centers for Medicare and Medicaid Services (CMS) administrator Mehmet Oz stand ready to implement these terms.&nbsp;According to the letter, the companies have till September 29 to comply.&nbsp;The VanEck Pharmaceutical ETF (PPH) dropped more than 2%, while the iShares U.S. Pharmaceutics ETF (IHE) edged 0.8% lower.&nbsp;Read also:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/sec-chair-unveils-project-crypto-to-back-trump-push-for-us-crypto-dominance/choLhyMRdG4">SEC Chair Unveils ‘Project Crypto’ To Back Trump’s Push For US Crypto Dominance</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.&nbsp;

Donald Trump gestures during a meeting with British Prime Minister Keir Starmer (not pictured) on July 28, 2025 in Turnberry, Scotland. (Photo by Christopher Furlong/Getty Images)

Trump To Issue 60-Day Warning Letters To Drugmakers Over Pricing 

The U.S. President is expected to send out these letters through his social media platform, Truth Social.

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ETFs on the Move Post U.S.-China Trade Deal

Morgan Stanley’s Wilson addresses 8 key investor questions

Sandoz CEO Richard Saynor has reportedly stated that the proposal to introduce a Europe-wide list price for new medicines is "deeply flawed."Saynor <a target="_blank" rel="noopener noreferrer nofollow" href="https://www.reuters.com/business/healthcare-pharmaceuticals/sandoz-ceo-slams-eu-wide-drug-price-proposal-warns-us-tariffs-will-hurt-patient-2025-04-28/">told</a> Reuters that the proposal, put forth by Novartis and Sanofi in a<a target="_blank" rel="noopener noreferrer nofollow" href="https://www.ft.com/content/de921b3c-988c-4d60-aca1-def85c70d299"> letter</a> to the Financial Times on Wednesday, overlooks the structural drivers of high drug prices in the United States and will not address global pricing inequities."It made me smile, made me laugh," Saynor said of the proposal.Sanofi and Novartis, in a proposal submitted last week, alleged that European price controls on medicines hinder innovation and proposed a Europe-wide list price for new medicines within the range of U.S. net prices.Saynor believes that the Trump administration will drive down prices for brand-name medicines. Some form of U.S. price reform, he said, is inevitable. &nbsp;However, big pharmaceutical companies should not hike prices in Europe to compensate, he added.U.S. patients have long borne a disproportionate share of costs for innovative medicines, while large drugmakers maintain high margins, the Sandoz CEO argued, citing Amgen’s autoimmune treatment Enbrel, which costs $70,000 per patient per year in the U.S. compared to $7,000 per patient in Europe.Switzerland-based Sandoz makes generic and biosimilar drugs, which are also sold in the U.S.The company's North America President, Keren Haruvi, has been meeting with White House officials nearly every week to discuss pharmaceutical imports and the U.S. reliance on foreign drug production, Saynor said, according to Reuters.Sandoz could be forced to withdraw some products from the U.S. market if significant tariffs are imposed, he added.Earlier this month, Sandoz <a href="https://stocktwits.com/news-articles/markets/equity/sandoz-files-antitrust-lawsuit-against-amgen-seeks-damages/chfCP48Rbac">filed</a> an antitrust lawsuit against Amgen, Inc., (AMGN), alleging that the latter is blocking competition to its drug Enbrel by unlawfully purchasing certain patent rights.Sandoz’s Erelzi is a biosimilar of Amgen’s Enbrel, a medicine used to treat a range of inflammatory diseases.Sandoz alleged that Amgen blocked competition from more cost-effective biosimilar competitors, including Erelzi, which received approval from the U.S. Food and Drug Administration (FDA) in 2016, using certain patent rights to entrench its position in the market.Many Americans could benefit from the cost savings and expanded access resulting from the introduction of high-quality, more affordable biosimilar options, the company said.Also See: <a href="https://stocktwits.com/news-articles/markets/equity/hsbc-double-downgrades-eli-lilly/chQx6M5RbhN">Eli Lilly Stock Gets A Double Downgrade And Price Target Cut By HSBC Over Valuation, Competition Concerns</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, the Swiss pharmaceuticals company Sandoz Group AG logo seen displayed in front of business webpage. (Photo Illustration by Timon Schneider/SOPA Images/LightRocket via Getty Images)

Sandoz CEO Richard Saynor Slams Proposal For Europe-Wide List Price For New Medicines, Says Report

Saynor told Reuters that the proposal, put forth by Novartis and Sanofi in a letter to the Financial Times on Wednesday, overlooks the structural drivers of high drug prices in the United States and will not address global pricing inequities.

Investors are most bearish in 30 years, BofA survey finds

Investing.com -- Investor sentiment has deteriorated to its most bearish point in three decades, according to the latest BofA Global Fund Manager Survey (FMS).

Pharma stocks up on US tariff exemptions but analyst flags a $46B import cost risk

Investing.com -- Pharmaceutical stocks saw brief relief Thursday after U.S. President Donald Trump left drug products off the list of newly announced tariffs. However, industry leaders and analysts cautioned that the sector is not in the clear, as targeted levies may still be on the horizon.

Shares of Xeris Biopharma Inc. surged more than 9.5% on Thursday, reaching their highest level since June 2021, driven by a better-than-expected revenue forecast for 2025 that fueled investor optimism.&nbsp;The rally came despite a slightly wider-than-expected quarterly loss, with retail sentiment increasingly bullish following the earnings release.Xeris reported an adjusted fourth-quarter loss of $0.03 per share, narrowly missing Wall Street expectations of a $0.02 loss.&nbsp;However, revenue for the period was $60.01 million, exceeding the consensus estimate of $58.54 million.&nbsp;The company's full-year guidance emerged as the key driver of market enthusiasm. Xeris expects 2025 revenue of $255 million to $275 million, significantly higher than the $239.77 million analysts had expected.CEO John Shannon described 2024 as an "exceptional" year, as revenue surpassed $203 million to a record high.&nbsp;CFO Steven Pieper said record quarterly revenue of more than $60 million in&nbsp;Q4 contributed to a positive cash flow of $2 million and adjusted&nbsp;earnings before interest, taxes, depreciation, and amortization (EBITDA) of over $8 million.&nbsp;He added that the 2025 revenue outlook represents more than 30% growth at the midpoint.Xeris currently markets three key products: Recorlev for endogenous Cushing's syndrome, Gvoke for severe hypoglycemia, and Keveyis for primary periodic paralysis.&nbsp;It is also advancing a pipeline of development programs, led by XP-8121, a Phase 3-ready, once-weekly subcutaneous injection for hypothyroidism, alongside several early-stage programs leveraging its technology platforms.On Stocktwits, sentiment for Xeris turned 'extremely bullish' (89/100) and reached its highest score in a year, with message volume surging by 780% in the 24 hours to Thursday's close.&nbsp;<figure class="image"><img style="aspect-ratio:1316/302;" src="https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/XERS_sentiment_and_message_volume_as_of_March_6_14ecb19082.png" alt="XERS sentiment and message volume as of March 6.png" width="1316" height="302"><figcaption>XERS sentiment and message volume as of March 6 | source: Stocktwits</figcaption></figure>One user noted that the stock's long period of stagnation, "like 40 qtrs in the desert," had finally given way to momentum.&nbsp;<stembedurl>https://stocktwits.com/NobVega/message/607012972</stembedurl>Another speculated about the possibility of a buyout, suggesting that Xeris could attract an acquisition offer by the end of the year.<stembedurl>https://stocktwits.com/Finwizard61/message/607030000</stembedurl>Short interest in Xeris last stood at 6.9%, according to Koyfin data. The company's stock, which was falling after-hours on Thursday, has gained nearly 22% since the start of the year.&nbsp;For updates and corrections, email newsroom[at]stocktwits[dot]com.

Representative image of a stock chart on black background. | Image source: Getty Images

Xeris Biopharma Stock Soars To Nearly 4-Year High On Strong 2025 Outlook, Retail Bulls Charge In

The company expects full-year revenue of $255 million to $275 million, significantly higher than the $239.77 million analysts had expected.

Shares of Esperion Therapeutics (ESPR) surged over 12% on Tuesday, marking their best session since early December, as the pharmaceutical company posted a strong fourth-quarter report that exceeded expectations.Esperion reported a quarterly loss of $0.11 per share, better than a consensus estimate of a $0.16 loss.&nbsp;Revenue came in at $69.1 million, surpassing expectations of $61.58 million.&nbsp;CEO Sheldon Koenig said Esperion expects to drive further revenue gains and reach operating profitability through the expansion of its bempedoic acid products in the U.S. and Europe, as well as global expansion into key markets like Japan.Effective Jan. 29, 2025, the U.S. Department of Defense added Esperion’s NEXLETOL (bempedoic acid) and NEXLIZET (bempedoic acid and ezetimibe) to its Uniform Formulary as preferred agents, covering nine million lives.&nbsp;The company also expanded its prescriber base, now reaching over 25,000 healthcare practitioners — a 10% increase from Q3.Esperion has initiated the development of two triple-combination products in the U.S., incorporating bempedoic acid, ezetimibe, and either atorvastatin or rosuvastatin.&nbsp;The company believes these formulations could offer low-density lipoprotein cholesterol (LDL-C) reductions exceeding 60%, positioning them as competitive alternatives to existing and emerging injectable and oral cholesterol-lowering therapies.Esperion said its Japanese partner, Otsuka Pharmaceutical Co., Ltd., has submitted a New Drug Application for bempedoic acid in the Asian country for the treatment of hypercholesterolemia and familial hypercholesterolemia.&nbsp;Otsuka anticipates approval and National Health Insurance pricing in the second half of 2025.H.C. Wainwright &amp; Co. reportedly maintained its $16.00 price target on Esperion, implying an 800% upside from current levels, according to Dow Jones newswires.On Stocktwits, sentiment remained ‘extremely bullish’ as message volume spiked 13% in the 24 hours to Tuesday's close.&nbsp;<figure class="image"><img style="aspect-ratio:1316/316;" src="https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/ESPR_sentiment_and_message_volume_as_on_March_4_4d838f95e8.png" alt="ESPR sentiment and message volume as on March 4.png" width="1316" height="316"><figcaption>ESPR sentiment and message volume as on March 4 | source: Stocktwits</figcaption></figure>One user speculated on the potential for growing royalties from international markets like Japan, Australia, and Israel.<stembedurl>https://stocktwits.com/theDeathStar/message/606790322</stembedurl>Another user suggested Otsuka could expand its partnership or buyout Esperion — rather than Daiichi Sankyo — on the back of its $20 billion cash reserves and stated plans for acquisitions this year.<stembedurl>https://stocktwits.com/djohnson591/message/606725247</stembedurl>Esperion originally signed a licensing agreement with Daiichi Sankyo Europe in 2019, granting exclusive rights to commercialize bempedoic acid products in the European Economic Area and Switzerland.<a href="https://stocktwits.com/symbol/ESPR">Esperion shares</a> remain down more than 20% year-to-date.For updates and corrections, email newsroom[at]stocktwits[dot]com.

Rising stock market chart on a trading board background.

Esperion Therapeutics Retail Bulls Charge In As Stock Notches Best Day In 3 Months On Impressive Q4

CEO Sheldon Koenig expects to drive further revenue gains and reach operating profitability through the expansion of its bempedoic acid products in the U.S. and Europe and global expansion into key markets.

SPDR Series Trust - SPDR Pharmaceuticals ETF

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