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A project grown out of the community's love and passion for the weed culture. Launched around early 2025, $weedcoin, “Like Bitcoin but way higher,” emphasizes its alignment with cannabis culture and a laid-back vibe. Unlike other Weed communities, this project leans heavily into community engagement over technical utility, aiming to build a “stoner community” through social media presence and decentralized governance. We also aim to focus on onboarding web2 businesses and users onto web3 through the token.

Weedcoin

Weedcoin is capturing market attention as a culture-focused crypto project on Solana that leverages cannabis-related narratives and community engagement ahead of seasonal industry milestones. Supporters emphasize its long-term development and grassroots approach, positioning the token as a decentralized alternative to traditional cannabis market equities.

Trump Media & Technology Group Corp. engages in operating social media and in the technology business. Its brands include TRUTH Social, TMTG+, and TMTG News. It operates through the Media and Truth.Fi segments. The Media segment includes products and services such as advertisement through the Truth Social platform. The Truth.Fi segment relates to customized exchange-traded funds or exchange-traded products invested in America First principles, and bitcoin and similar cryptocurrencies or crypto-related securities. The company was founded on March 28, 2024 and is headquartered in Sarasota, FL.

Trump Media & Technology Group Corp.

DJT is trending as investors react to a high-stakes, prime-time address where the administration outlined plans for an intensified military campaign in Iran. The community is sharply divided, with intense debate occurring over the potential for prolonged conflict, its impact on global energy prices, and broader concerns regarding the administration's leadership and stability.

United States Oil Fund LP - United States Oil Fund

United States Oil Fund

United States Oil Fund (USO) is experiencing high volatility as market participants weigh conflicting signals regarding a potential ceasefire against President Trump's recent vows to intensify military actions in Iran. The community remains deeply divided, with many traders aggressively betting on further supply disruptions and sustained high energy prices, while others warn of potential market manipulation and a possible correction if the geopolitical situation de-escalates.

SPDR S&P 500 ETF TRUST - Units of undivided interest in SPDR Trust Series 1

Market sentiment for the S&P 500 has soured following a presidential address that signaled a prolonged military conflict in Iran, contradicting earlier hopes for rapid de-escalation and a swift end to hostilities. Investors are now actively debating the economic implications of surging oil prices, with many in the community expressing frustration over market volatility and skepticism regarding the administration's strategic objectives.

Kelly Services, Inc. engages in the provision of talent solutions. It operates through the following segments: Professional and Industrial, Science, Engineering, and Technology, Education, Outsourcing and Consulting, and International. The Professional and Industrial segment includes the provision of administrative, accounting and finance, light industrial, contact center staffing, and other workforce solutions. The Science, Engineering, and Technology segment focuses on staffing, outcome-based, permanent placement services, clinical research, and telecommunications. The Education segment involves offering education and therapy services talent through staffing, permanent placement, and executive search services to Pre-K-12 school districts and organizations. The Outsourcing and Consulting segment consists of global talent supply chain and workforce solutions, including Managed Service Provider (MSP), Recruitment Process Outsourcing (RPO), Payroll Process Outsourcing (PPO), and executive coaching programs. The company was founded by William Russell Kelly on October 7, 1946 and is headquartered in Troy, MI.

Kelly Services, Inc. - Ordinary Shares - Class B

Kelly Services (KELYB) is trending as investors bet on a short squeeze fueled by an extremely low public float of approximately 255,000 shares, following a significant stake acquisition by Hunt Equity. Community sentiment remains deeply divided between those anticipating a repeat of recent parabolic price spikes and those frustrated by heavy shorting, dark pool volume, and frequent trading halts.

Invesco QQQ Trust Series 1 - Units of beneficial interest

The Invesco QQQ Trust is experiencing significant volatility as market participants weigh geopolitical tensions against President Trump's recent statements regarding a prolonged escalation in the Middle East. Traders are actively debating whether current price action represents a bear trap or a necessary correction, with many expressing skepticism toward the sustainability of recent rallies given persistent macro headwinds and energy supply concerns.

“This Is Fine” is unique as a meme for two reasons. One, while sometimes modified, it’s most commonly used in an unaltered state. Second, it’s still popular and used, despite now being nearly nine years old. $Fine is a both a meme and culture coin, meaning it is heavily focused on the use of memes and community engagement.  You can get involved with $Fine by purchasing tokens on Uniswap, participating in community discussions on Telegram, Twitter or medium, and spreading the word about $Fine through memes. You can sell your $fine tokens on Uniswap, but the project encourages holding onto them and participating in the community to drive the price up.  Longevity and Unaltered State:  One of the distinctive aspects of the $Fine token is its association with the "This Is Fine" meme. Unlike other memes that often undergo modifications or alterations over time, the $Fine meme is primarily used in its original, unaltered state. This contributes to its enduring popularity and recognition. Enduring Popularity:  Remarkably, despite being almost a decade old, the "This Is Fine" meme remains popular and widely used. This enduring popularity serves as a testament to its cultural significance and the impact it has had on internet culture. Meme and Culture Coin:  $Fine transcends the traditional notion of a cryptocurrency and is categorized as a "meme and culture coin." This designation indicates a strong emphasis on leveraging memes and fostering community engagement as integral components of the project's identity and development.

Refinable

Investors are actively discussing the potential of this meme coin, highlighting its low market cap and wide holder distribution as key factors that could support a significant price rally. The community is heavily focused on the project's ties to established developers and the anticipation of new catalysts like AI meme-generation tools, while also expressing frustration over the lack of an accurate, dedicated ticker page on the platform.

Kratos Defense & Security Solutions, Inc. engages in the provision of mission critical products, services and solutions for United States national security priorities. It operates through the Kratos Government Solutions (KGS) and Unmanned Systems (US) segments. The KGS segment consists of an aggregation of KGS operating segments, including microwave electronic products, space, satellite and cyber, training solutions. The US segment refers to the unmanned aerial, unmanned ground, unmanned seaborne and related command, control and communications system businesses. The company was founded on December 19, 1994, and is headquartered in Round Rock, TX.

Kratos Defense & Security Solutions Inc

Kratos Defense & Security Solutions is trending as investors grapple with recent insider activity and a massive capital raise aimed at scaling production to meet surging demand for unmanned aerial systems and hypersonic testing. While some market participants are reacting with caution to short-term volatility and guidance, the broader community remains highly bullish, citing the company's critical role in a rapidly evolving defense landscape and its strong position within key future war pillars like autonomous drones.

Applied Digital Corporation

Applied Digital is trending amid high volatility, as investors weigh potential geopolitical catalysts and ongoing uncertainty surrounding the Iran conflict against strong institutional support and anticipation of upcoming earnings. The community is actively debating the impact of future hyperscaler lease announcements, with many viewing the current price action as a de-risking event driven by macro factors rather than a shift in long-term company fundamentals.

Vine Hill Capital Investment Corp. is a blank check company, which was created for the purpose of effecting a merger, capital stock exchange, asset acquisition, stock purchase, reorganization, or similar business combination with one or more businesses. The company was founded on May 24, 2024 and is headquartered in Fort Lauderdale, FL.

CoinShares Plc.

CoinShares is experiencing heightened volatility following its recent SPAC merger and transition to a Nasdaq listing, with investors debating whether the current valuation reflects a discount or ongoing geopolitical headwinds. The community remains focused on potential float discrepancies and the firm's long-term integration within the crypto-asset management sector.

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<ul class="summary-bullets"><li>Due to continued war and strikes in the middle-east region, Brent crude is expected to cross $100 per barrel resulting in a bull run in oil stocks.&nbsp;</li><li>Pennzoil Quaker State Company DBA SOPUS Products, a wholly owned subsidiary of Shell USA, will sell Jiffy Lube International to an affiliate of Monomoy Capital Partners for $1.3 billion.&nbsp;</li><li>Shell will retain its Pennzoil Quaker State, Rotella and other Shell lubricants brands.</li></ul><p>U.S. listed shares of Shell jumped more than 2% on Monday helped by rising oil prices as well as the oil producer divesting Jiffy Lube International and Premium Velocity Auto for $1.3 billion.&nbsp;</p><p>Pennzoil Quaker State Company DBA SOPUS Products, a wholly owned subsidiary of Shell USA, Inc., that comprises Shell's United States lubricants business, has entered an agreement to sell Jiffy Lube International and its subsidiary Premium Velocity Auto business to an affiliate of Monomoy Capital Partners for $1.3 billion.&nbsp;</p><p>Shell is the leading deep-water operator and largest producer of oil and gas in the U.S. Gulf of America and the largest buyer of U.S. LNG.&nbsp;</p><h2 class="st-heading-2">Details</h2><p>The sale includes the Jiffy Lube brand and a network of franchised stores which are owned and operated by independent franchisees, in addition to franchised stores that are owned and operated by PVA.&nbsp;</p><p>Shell will retain its Pennzoil Quaker State, Rotella and other Shell lubricants brands, along with marketing, manufacturing and distribution of lubricants in the U.S. and Canada that serve consumer, commercial and industrial sectors.</p><p>"By capitalizing on a strong market opportunity, this divestment allows us to monetize an asset that is not central to Shell's lubricant's portfolio in the US and reinvest in opportunities that generate higher returns," said Machteld de Haan, President, Downstream, Renewables and Energy Solutions, Shell plc.</p><p>The transaction is expected to close in the second half of 2026, subject to regulatory approval and other closing conditions.</p><h2 class="st-heading-2">Oil Stocks In Focus&nbsp;</h2><p>Oil stocks have been in focus ever since war broke out between U.S.-Israel and Iran as it has led to blockade of a critical sea route of Strait of Hormuz through which almost 20% of global crude and LNG passes.&nbsp;</p><p>Due to continued war and strikes in the middle-east region, Brent crude is expected to cross $100 per barrel resulting in a bull run in oil stocks.&nbsp;</p><h2 class="st-heading-2">How Did Stocktwits Users React?</h2><p>Retail sentiment around SHEL trended in ‘neutral’ territory amid ‘high’ message volume.&nbsp;</p><p>Shares in the company have risen 17% year-to-date.&nbsp;</p><p><i>For updates and corrections, email newsroom[at]stocktwits[dot]com.</i></p>

The Shell logo displayed at a Shell gas station in Edmonton, Alberta, Canada, on March 22, 2025. 

Shell Stock Hits 52-Week High – Here’s Why

Rise in oil prices amid the ongoing conflict in the middle-east has spiked Brent crude and other energy product prices. 

Equity

Rise in oil prices amid the ongoing conflict in the middle-east has spiked Brent crude and other energy product prices. 


<ul class="summary-bullets"><li>A Novo executive noted that many customers are unaware that the company already makes oral semaglutide for type 2 diabetes under the name Rybelsus, sparking the branding change.</li><li>Novo also said on Wednesday that it has filed an application with the FDA seeking approval for Ozempic tablets 25 mg in adults with type 2 diabetes.</li></ul><p>Danish drugmaker Novo Nordisk (NVO) said on Wednesday that the U.S. Food and Drug Administration has approved naming pill versions of some doses of its semaglutide for the treatment of type 2 diabetes as Ozempic pills.</p><p>Novo has been selling oral semaglutide for diabetes since 2019. However, it was previously called Rybelsus and was available at 3 mg, 7 mg, and 14 mg doses. Ozempic pills will be available in doses 1.5 mg, 4 mg, and 9 mg.</p><h2 class="st-heading-2">Why The Name Change?</h2><p>“By bringing the oral and injectable options under the Ozempic name, we’re helping make it clear that both contain semaglutide from Novo Nordisk and are approved to treat type 2 diabetes. The medicine and how it works remain the same; this simply makes the choices clearer to understand. There’s only One Ozempic…now in two presentations.” <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.novonordisk-us.com/media/news-archive/news-details.html?id=916488">said</a> Ed Cinca, Senior Vice President of Marketing &amp; Patient Solutions at Novo Nordisk.</p><p>Cinca also noted that many customers are unaware that the company already makes oral semaglutide for type 2 diabetes under the name Rybelsus, sparking the branding change.</p><h2 class="st-heading-2">Launch Timeline</h2><p>The Ozempic pill will be launched in Q2 2026. The new formulation offers the same efficacy and safety profile as the originally approved formulation, the company said, while adding that the new doses were approved based on a bioequivalence study and the clinical trial program for Rybelsus tablets.</p><p>Novo got the approval of the U.S. Food and Drug Administration (FDA) for the Wegovy pill in December last year and launched it in early January. The weight-loss drug has had a great kickstart so far.</p><p>Novo also said on Wednesday that it has filed an application with the FDA seeking approval for Ozempic tablets 25 mg in adults with type 2 diabetes. The company now expects the agency to provide a decision on the application by 2026-end.</p><h2 class="st-heading-2">Flat Growth In Diabetes Segment</h2><p>Novo on Tuesday said that sales from its diabetes segment remained more-or-less flat on a reported basis in 2025 at DKK 207.11 billion while sales from its obesity segment increased 26% in Danish kroner to DKK 82.35 billion.</p><p>The company now expects adjusted sales to fall between 5% and 13%, and operating profit could decline by up to 13%. The company flagged concerns for the year including fierce competition, lower realized prices, and expiry of patent on the active ingredient in its best-selling Wegovy and Ozempic drugs in a few markets outside the U.S.</p><h2 class="st-heading-2">How Did Stocktwits Users React?</h2><p>On Stocktwits, retail sentiment around NVO stock stayed within the ‘bullish’ territory while message volume increased from ‘high’ to ‘extremely high’ levels.</p><p><a href="https://stocktwits.com/symbol/NVO">NVO stock</a> has fallen 43% over the past 12 months.&nbsp;</p><p>Read More: <a href="https://stocktwits.com/news-articles/markets/equity/rklb-asts-stocks-dip-amid-selloff-after-spacex-xai-merger-spurred-rally/cZbj9ElR4NO">RKLB, ASTS Stocks Dip Amid Selloff After SpaceX-xAI Merger Spurred Rally</a></p><p><i>For updates and corrections, email newsroom[at]stocktwits[dot]com.</i></p>

In this photo illustration, the logo of Novo Nordisk is displayed on a smartphone screen on September 10, 2025 in Chongqing, China. 

Novo Nordisk To Launch Ozempic Pills Following Flat Growth In Diabetes Segment In 2025

The Ozempic pill will be launched in Q2 2026 and be available in doses 1.5 mg, 4 mg, and 9 mg.

<ul class="summary-bullets"><li>The company flagged concerns for the year including fierce competition, lower realized prices, and expiry of patent on the active ingredient in its best-selling Wegovy and Ozempic drugs in a few markets outside the U.S.&nbsp;</li><li>The updated guidance comes on the heels of the company reporting full-year 2025 net sales of DKK309.06 billion, below an analyst estimate of DKK346.97 billion.</li><li>Novo’s sales from its diabetes segment remained more-or-less flat on a reported basis in 2025 at DKK207.11 billion while sales from its obesity segment increased 26% in Danish kroner to DKK82.35 billion.</li></ul><p>Shares of Danish drugmaker Novo Nordisk (NVO) plummeted 14% on Tuesday after the company said that it sees fiscal 2026 adjusted sales down 5% to 13% as it gears up to face pricing headwinds and a competitive market.</p><p>The company <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://ml-eu.globenewswire.com/Resource/Download/7c7c1d6f-42c0-4e8f-821c-93ff9a0858c0">flagged </a>concerns for the year including fierce competition, lower realized prices, and expiry of patent on the active ingredient in its best-selling Wegovy and Ozempic drugs in a few markets outside the U.S.</p><p>Novo also sees adjusted operating profit fall as much as 13% in fiscal 2026 at constant exchange rates.</p><h2 class="st-heading-2">2025 Earnings</h2><p>The updated guidance comes on the heels of the company reporting full-year 2025 net sales of DKK309.06 billion ($48.94 billion), up 6% year-over-year on a reported basis, but below an analyst estimate of DKK346.97 billion.</p><p>Diluted earnings per share for the year came in at DKK23.03, up from DKK22.63 in 2024, and below a Wall Street estimate of DKK23.4.</p><p>Operating profit, meanwhile, decreased by 1% in Danish kroner to DKK127.66billion.</p><h2 class="st-heading-2">Executive Take</h2><p>CEO Mike Doustdar said that 2025 was a "challenging year” for the company.</p><p>“However, we are very encouraged by the promising early uptake from the US launch of Wegovy pill, and we remain confident in our ability to drive volume growth over the coming years,” Doustdar said.</p><p>“Also for this year, we look forward to regulatory decisions for next-generation treatments, such as Mim8 within haemophilia and CagriSema within obesity, as well as a number of exciting R&amp;D read-outs, including phase 3 read-outs for etavopivat and ziltivekimab," he added.</p><p>Novo got the approval of the U.S. Food and Drug Administration (FDA) for the Wegovy pill in December last year and launched it in early January. The drug has had a great kickstart so far.</p><p>In contrast, rival Eli Lilly and Co. (LLY) is still awaiting FDA approval on its oral weight-loss drug, giving Novo a few months of solid head start to cement its position in the market. However, Lilly is currently overtaking Novo in injectable weight loss drugs. &nbsp;</p><h2 class="st-heading-2">Blockbuster Drug Sales</h2><p>Novo said on Tuesday that sales from its diabetes segment remained more-or-less flat on a reported basis in 2025 at DKK 207.11 billion while sales from its obesity segment increased 26% in Danish kroner to DKK 82.35 billion.</p><p>Sales of the company’s blockbuster diabetes drug Ozempic came in at DKK130.11 billion for the year, while Wegovy sales came in at DKK79.11 billion.</p><h2 class="st-heading-2">How Did Stocktwits Users React?</h2><p>On Stocktwits, retail sentiment around NVO stock rose from ‘neutral’ to ‘bullish’ territory over the past 24 hours, while message volume rose from ‘low’ to ‘high’ levels.</p><p><a href="https://stocktwits.com/symbol/NVO">NVO stock</a> has dropped about 39% over the past 12 months.</p><p>Read More: <a href="https://stocktwits.com/news-articles/markets/equity/tesla-continues-to-rejig-lineup-in-run-up-to-vehicle-autonomy/cZb0GTWR4mS">Tesla Continues To Rejig Lineup In Run Up To Vehicle Autonomy</a></p><p><i>For updates and corrections, email newsroom[at]stocktwits[dot]com.</i></p><p><i>Exchange Rate: DKK1= $0.16</i></p>

Novo Nordisk Shares Tumble On 2025 Earnings Miss, Weak Sales Forecast And Competition Concerns

The drugmaker now expects fiscal 2026 adjusted sales down 5% to 13%.

<ul class="summary-bullets"><li>Keefe kept a price target of $3 up from $2.50 on the stock.&nbsp;</li><li>Keefe has concerns around Bitfarms's rising leverage and elevated capex.&nbsp;</li><li>The firm said it does not expect a leasing agreement to materialize for BITF until the second half of 2026.</li></ul><p>Shares of Bitfarms were down more than 1% during after hours of trading on Monday after an analyst raised liquidity concerns for the firm.&nbsp;</p><p>Shares in the company closed down 5.5% on Monday.&nbsp;</p><h2 class="st-heading-2">Liquidity Risks</h2><p>Keefe Bruyette downgraded Bitfarms to ‘Market Perform’ from ‘Outperform’ with a price target of $3, up from $2.50.&nbsp;</p><p>The firm said it does not expect a leasing agreement to materialize for the company until the second half of 2026. The stock already discounts a Sharon deal, said Keefe, which also has concerns around Bitfarms's rising leverage and elevated capex.&nbsp;</p><p>Keefe said it would get more constructive on the shares with greater clarity on the company's liquidity and 2026 capex.</p><h2 class="st-heading-2">Capital Raises</h2><p>Bitfarms in October had said that it has closed its offering of $588 million aggregate principal amount of 1.375% convertible senior notes due 2031. It said that Interest coupon will be payable semi-annually in arrears on January 15 and July 15 of each year, beginning on July 15, 2026.</p><p>Bitfarms had also converted a private debt facility for up to $300 million from Macquarie Group’s Commodities and Global Markets business, to an up to $300 million project-specific financing facility for the development of its data center campus in Panther Creek, Pennsylvania.</p><h2 class="st-heading-2">AI Data Center Push</h2><p>Bitfarm in 2024 had entered into the definitive lease agreement and assumed control of its newest data center in Sharon, Pennsylvania, initially announced on June 13, 2024.</p><p>This site represented Bitfarms’ first mega-site in the U.S. with access to up to 120 MW.&nbsp;</p><p>Bitfarms has planned to wind down its Bitcoin mining operations by 2027, and its transition will begin with its 18-megawatt site in Washington State.</p><h2 class="st-heading-2">LatAm Exit Deal</h2><p>BITF earlier in the month said it has entered into a share purchase agreement to sell its 70 MW site in Paso Pe, Paraguay, to the Sympatheia Power Fund (SPF), a crypto infrastructure fund managed by Singapore-based Hawksburn Capital.</p><p>The deal was valued at $30 million. Bitfarms would receive $9 million in cash upon closing, expected in Q1 2026, and up to $21 million over 10 months following closing, based on certain payment milestones, it had stated.</p><h2 class="st-heading-2">How Did Stocktwits Users React?</h2><p>Retail sentiment around BITF trended in ‘bearish’ territory amid ‘low’ message volume.</p><p>Shares in the company have risen 65% over the past 12 months.&nbsp;<br>&nbsp;</p>

In this photo illustration, the Bitfarms Ltd logo is seen on a smartphone screen. 

Why Bitfarms Stock Is Down After Hours?

Keefe Bruyette downgraded Bitfarms to ‘Market Perform’ from ‘Outperform’. 

<ul class="summary-bullets"><li>Reuters noted that oral Wegovy’s debut is stronger than observed with Novo’s injectable Wegovy or its rival Eli Lilly and Company’s Zepbound.&nbsp;</li><li>Novo’s rival Lilly, meanwhile, is looking forward to getting FDA approval for its oral obesity drug Orforglipron by April.</li></ul><p>Danish drugmaker Novo Nordisk’s (NVO) Wegovy pill reportedly hit over 18,000 U.S. prescriptions in the first full week after its launch, marking a strong start for the oral weight-loss pill. &nbsp;</p><p>Reuters <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.reuters.com/business/healthcare-pharmaceuticals/novos-wegovy-pill-tracks-18410-prescriptions-first-full-week-since-launch-2026-01-23/">reported</a> on Friday, citing IQVIA data shared by analysts, that Novo’s weight-loss pill was prescribed 18,410 times in the week ended January 16. As per the report, this is a stronger debut than observed with Novo’s injectable Wegovy or its rival Eli Lilly and Company’s Zepbound.</p><p>Last week, it was reported that the Wegovy pill hit 3,071 U.S. prescriptions in just the first four days after its launch on Jan 5.</p><p>NVO shares traded marginally in the green on Friday at the time of writing.</p><h2 class="st-heading-2">Wegovy Pill Approval</h2><p>Oral obesity pills are expected to be the next major innovation in the obesity market, doing away with needles and offering customers more flexibility and ease.</p><p>The U.S. Food and Drug Administration (FDA) approved the Wegovy pill to reduce body weight and maintain weight reduction for a longer term in December.</p><p>The Wegovy pill is now the first FDA-approved oral GLP-1 class drug for weight management and marks a crucial step forward for the company in its ongoing efforts to protect market share from rival Eli Lilly, whose injectable GLP-1 drug Zepbound is fast taking over Wegovy’s market dominance. The company launched the Wegovy pill earlier this month, starting at $149 a month.</p><p>Novo’s rival Lilly, meanwhile, is looking forward to getting FDA approval for its oral obesity drug Orforglipron by April. Novo now has a few months’ head start against Lilly to cement its customer base.</p><p>On Thursday, Goldman Sachs raised its price target on Novo Nordisk to DKK 436 from DKK 352 while keeping a ‘Buy’ rating on the shares. The firm believes investor focus in the first half of 2026 will be the launch for Novo's Wegovy pill. The weight loss pill should contribute to positive earnings momentum in the near term, the analyst told investors, as per TheFly.</p><h2 class="st-heading-2">How Did Stocktwits Users React?</h2><p>On Stocktwits, retail sentiment around NVO stock stayed within the ‘bullish’ territory, while message volume fell from ‘high’ to ‘normal’ levels.</p><p><a href="https://stocktwits.com/symbol/NVO">NVO shares</a> have fallen 23% over the past 12 months.</p><p>Read More: <a href="https://stocktwits.com/news-articles/markets/equity/bhc-stock-plummets-on-failed-liver-cirrhosis-trial/cmyRgOmR4gz">Tesla’s Market Share Dives In EV Stronghold California In 2025, Paving Way For Asian Rival’s Growth</a></p><p><i>For updates and corrections, email newsroom[at]stocktwits[dot]com.</i></p>

Novo Nordisk In Green After Oral Wegovy Clocks Over 18K Prescriptions In A Week

Reuters reported on Friday, citing IQVIA data shared by analysts, that Novo’s weight-loss pill was prescribed 18,410 times in the week ended January 16.

<ul class="summary-bullets"><li>CEO Thomas J. Appio said that the company is “disappointed in the results.”</li><li>The experimental therapy, however, was safe and well-tolerated, the company said.</li><li>Rifaximin is already approved in the U.S. and marketed as Xifaxan.</li></ul><p>Shares of Bausch Health Companies Inc. (BHC) fell 10% on Friday after the company said that its late-stage program evaluating amorphous-rifaximin solid soluble dispersion (SSD) in adults with liver cirrhosis failed to meet its primary goal.</p><p>The clinical program <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://ir.bauschhealth.com/news-releases/2026/01-23-2026-124516159">evaluated</a> rifaximin SSD for the delay of the first episode of hepatic encephalopathy (HE) in adults with liver cirrhosis who experienced no prior episodes. The program consisted of two global trials involving more than 1000 patients.</p><p>Hepatic encephalopathy is a serious brain dysfunction caused by liver failure, where the liver can't remove toxins from the blood, allowing them to build up and affect the brain, causing confusion, personality changes, slurred speech, and lethargy, potentially leading to coma.</p><h2 class="st-heading-2">Executive Takeaway</h2><p>CEO Thomas J. Appio said that the company is “disappointed in the results.” The experimental therapy, however, was safe and well-tolerated, the company said.</p><p>“We are currently reviewing the full dataset to determine potential new development opportunities," he said while adding that the company remains committed to bringing new treatments to patients across hepatology and other therapeutic areas.</p><p>Rifaximin is already approved in the U.S. and marketed as Xifaxan which is slated to lose exclusivity in 2028. The recent trials were evaluating a new variant of the compound.</p><h2 class="st-heading-2">How Did Stocktwits Users React?</h2><p>On Stocktwits, retail sentiment around BHC stock rose from ‘bearish’ to ‘bullish’ territory over the past 24 hours, while retail chatter rose from ‘high’ to ‘extremely high’ levels.</p><p>A Stocktwits user expressed anticipation for the company’s quarterly report in February, saying the company “lost &nbsp;a &nbsp;Battle but not &nbsp;the &nbsp;war.”</p><p><stembedurl>https://www.stocktwits.com/Valmaro/message/642700352</stembedurl></p><p>Another user, however, opined that the trial failure is “a serious blow” to the company’s future prospects.</p><p><stembedurl>https://www.stocktwits.com/Contrarian_Dan/message/642693387</stembedurl></p><p><a href="https://stocktwits.com/symbol/BHC">BHC stock</a> has dropped 24% over the past 12 months.&nbsp;</p><p>Read More: <a href="https://stocktwits.com/news-articles/markets/equity/tesla-market-share-dives-in-ev-stronghold-california-in-2025-paving-way-for-asian-rivals-growth/cmUCgvWR4X8">Tesla’s Market Share Dives In EV Stronghold California In 2025, Paving Way For Asian Rival’s Growth</a></p><p><i>For updates and corrections, email newsroom[at]stocktwits[dot]com.</i></p>

 In this photo illustration, the Bausch Health logo is displayed on the screen of a tablet. (Photo Illustration by Sheldon Cooper/SOPA Images/LightRocket via Getty Images)

BHC Stock Plummets On Failed Liver Cirrhosis Trial: Retail Says ‘Lost Battle But Not The War’

The failed clinical program evaluated rifaximin SSD for the delay of the first episode of hepatic encephalopathy (HE) in adults with liver cirrhosis who experienced no prior episodes.

<ul class="summary-bullets"><li>Novo and Aspect have been collaborating since 2023 to develop cellular medicines.</li><li>Under the deal, Aspect has acquired rights to stem cell-derived islet cell and hypoimmune cell engineering technologies from Novo Nordisk and will now lead their development.&nbsp;</li><li>Novo, in turn, will make an additional equity investment in Aspect and provide research funding.</li></ul><p>Danish drugmaker Novo Nordisk (NVO) said on Tuesday that it is looking to develop new medicines for diabetes as part of its new partnership with Canadian biotech firm Aspect Biosystems.</p><p>Novo and Aspect have been collaborating since 2023 to develop cellular medicines. The companies <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.novonordisk.com/content/nncorp/global/en/news-and-media/news-and-ir-materials/news-details.html?id=916478">said</a> that the new partnership phase builds on the momentum achieved in the existing collaboration.</p><h2 class="st-heading-2">Deal Terms</h2><p>Under the deal, Aspect has acquired rights to stem cell-derived islet cell and hypoimmune cell engineering technologies from Novo Nordisk. This refers to technology allowing for making insulin-producing cells from stem cells for diabetes treatment and modifying cells to evade the immune system, thereby avoiding immune rejection. The privately-held company will now lead its development, manufacturing and commercialisation.</p><p>Novo, in turn, will make an additional equity investment in Aspect and provide research funding. It will also retain rights to expand its role in late-stage development and commercialisation as well. &nbsp;</p><p>Novo Nordisk will be eligible to receive royalties and milestone payments on future product sales from Aspect. However, the companies didn’t provide the financial terms of the agreement.</p><h2 class="st-heading-2">Novo On Lookout For More</h2><p>Last week, Novo said it is on the lookout for merger and acquisition deals to boost its drug portfolio.</p><p>Novo’s CEO Mike Doustdar said during the annual JP Morgan Healthcare conference that the company will continue searching for molecules, assets, and companies that are complementary to its portfolio. Doustdar said that the company can afford any amount for an asset, provided it is worth it.</p><p>Novo’s best-selling drugs now include Wegovy and Ozempic for weight loss and diabetes, respectively.</p><h2 class="st-heading-2">How Did Stocktwits Users React?</h2><p>On Stocktwits, retail sentiment around NVO stayed within the ‘bullish’ territory over the past 24 hours, while message volume stayed at ‘high’ levels.</p><p><a href="https://stocktwits.com/symbol/NVO">NVO shares</a> have fallen 25% over the past 12 months.&nbsp;</p><p>Read More: <a href="https://stocktwits.com/news-articles/markets/equity/lululemon-stock-slips-after-reportedly-removing-see-through-leggings-from-website/cmUuHw8R4OO">Lululemon Stock Slips 6% After Reportedly Removing “See-Through” Leggings From Website</a></p><p><i>For updates and corrections, email newsroom[at]stocktwits[dot]com.</i></p>

Novo Nordisk Inks Deal With Canada’s Aspect Biosystems To Find More Diabetes Meds Besides Ozempic

Novo and Aspect have been collaborating since 2023 to develop cellular medicines, and said that the new partnership phase builds on the momentum achieved in the existing collaboration.

<ul class="summary-bullets"><li>While the study also showed an improvement in other key aspects such as complete response rates and duration of response, it did not demonstrate a statistically significant improvement in overall survival.&nbsp;</li><li>Diffuse Large B-Cell Lymphoma (DLBCL) is the most common and aggressive type of non-Hodgkin lymphoma.</li><li>The company said it now intends to engage with regulatory authorities to discuss the next steps for the drug together with its partner AbbVie.</li></ul><p><br>Genmab A/S (GMAB) said on Friday that its late-stage trial evaluating drug Epcoritamab demonstrated an improvement in progression-free survival in certain patients with relapsed or refractory (R/R) diffuse large B-cell lymphoma.</p><p>While the study also showed an improvement in other key aspects such as complete response rates and duration of response, it did not demonstrate a statistically significant improvement in overall survival, the company <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/news-release/2026/01/16/3220513/0/en/Genmab-Announces-Topline-Results-for-Epcoritamab-DuoBody-CD3xCD20-from-Phase-3-EPCORE-DLBCL-1-Trial-in-Patients-with-Relapsed-Refractory-Diffuse-Large-B-cell-Lymphoma-DLBCL.html">said.</a> While progression-free survival represents the time a patient lives with cancer without it getting worse or dying, overall survival is the length of time from diagnosis or treatment start until death from any cause.</p><h2 class="st-heading-2">Study Details</h2><p>Genmab enrolled 483 patients with relapsed or refractory (R/R) diffuse large B-cell lymphoma in the trial who had undergone at least one prior line of therapy. These patients were ineligible for high-dose chemotherapy, the company said.</p><p>Diffuse Large B-Cell Lymphoma (DLBCL) is the most common and aggressive type of non-Hodgkin lymphoma, a blood cancer involving rapid growth of large B-lymphocytes in the lymphatic system, lymph nodes, and other organs, often presenting as fast-growing masses or swollen nodes with symptoms like fever, night sweats, and weight loss. According to Genmab, there are approximately 25,000 new cases of DLBCL diagnosed each year in the U.S.</p><p>The company said it intends to now engage with regulatory authorities to discuss the next steps for the drug together with its partner AbbVie. Epcoritamab, being co-developed by Genmab and AbbVie, is already approved in several countries for the treatment of certain lymphomas.</p><p>Shares of GMAB fell 5% at the time of writing.</p><h2 class="st-heading-2">How Did Stocktwits Users React?</h2><p>On Stocktwits, retail sentiment around GMAB stock stayed within the ‘bearish’ territory coupled with ‘high’ message volume.</p><p>Meanwhile, sentiment around ABBV shares rose from ‘bearish’ to ‘neutral’ territory over the past 24 hours, while message volume stayed at ‘extremely high’ levels.</p><p>A Stocktwits user sees GMAB stock plummet down to $20 from current levels.</p><p><stembedurl>https://www.stocktwits.com/nopumpdump/message/642093162</stembedurl></p><p><a href="https://stocktwits.com/symbol/GMAB">GMAB stock</a> has gained 51% over the past 12 months while <a href="https://stocktwits.com/symbol/ABBV">ABBV shares</a> added 24%.&nbsp;</p><p>Read More: <a href="https://stocktwits.com/news-articles/markets/equity/nvo-shares-rise-on-strong-kickstart-for-wegoy-pill-in-us/cmUlCCgR4Bq">NVO Shares Rise On Strong Kickstart For Wegovy Pill In US: Retail Eyes Up To $110 As ‘Fair Value’</a></p><p><i>For updates and corrections, email newsroom[at]stocktwits[dot]com.</i></p>

In this photo illustration, the Genmab logo is displayed on the screen of a tablet. (Photo Illustration by Sheldon Cooper/SOPA Images/LightRocket via Getty Images)

Genmab Stock Drops On Mixed Results From Late-Stage Trial Of Lymphoma Drug

Epcoritamab demonstrated an improvement in progression-free survival in certain patients with relapsed or refractory (R/R) diffuse large B-cell lymphoma, the company said.

Epcoritamab demonstrated an improvement in progression-free survival in certain patients with relapsed or refractory diffuse large B-cell lymphoma, the company said.


<ul class="summary-bullets"><li>If approved, Ianalumab could become the first targeted treatment for Sjögren’s disease.&nbsp;</li><li>The Breakthrough Therapy designation was granted to Novartis on the basis of clinical evidence supporting the drug’s potential.</li><li>In Novartis’ late-stage trials evaluating the efficacy and safety of Ianalumab in patients with Sjögren’s disease, the drug delivered a clinically meaningful benefit.</li></ul><p>Shares of Novartis (NVS) rose 1% on Friday after the U.S. Food and Drug Administration granted its drug Ianalumab a breakthrough therapy designation in the treatment of Sjögren’s disease.</p><p>Sjögren’s disease is a systemic, chronic autoimmune disorder that causes inflammation and tissue damage, impacting the entire body. It primarily affects exocrine glands, leading to excessive dryness, with over 90% of patients experiencing dry eyes and dry mouth.</p><p>According to Novartis, 50% of people with Sjögren’s are undiagnosed, though it is the second-most prevalent rheumatic autoimmune disease.</p><p>Novartis looks to submit data from its many trials of Ianalumab with health authorities starting in early 2026 for potential approval. If approved, it could become the first targeted treatment for Sjögren’s disease, as per Novartis.</p><h2 class="st-heading-2">The Designation</h2><p>The Breakthrough Therapy designation, <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.novartis.com/news/media-releases/novartis-ianalumab-receives-fda-breakthrough-therapy-designation-sjogrens-disease">granted</a> to Novartis on the basis of clinical evidence supporting the drug’s potential, is intended to expedite the review of medicines that treat a serious or life-threatening condition. Ianalumab was previously awarded the FDA’s Fast Track designation in 2016.</p><p>In Novartis’ late-stage trials that evaluated the efficacy and safety of Ianalumab in patients with Sjögren’s disease, the drug delivered a clinically meaningful benefit, showing improvement in disease activity and reductions in patient burden. Further, the drug demonstrated a favorable safety profile with an overall incidence of adverse events comparable to placebo.</p><h2 class="st-heading-2">How Did Stocktwits Users React?</h2><p>On Stocktwits, retail sentiment around NVS stock stayed within the ‘neutral’ territory over the past 24 hours, while message volume stayed at ‘high’ levels.</p><p><a href="https://stocktwits.com/symbol/NVS">NVS stock</a> has gained nearly 48% over the past 12 months.&nbsp;</p><p>Read More: <a href="https://stocktwits.com/news-articles/markets/equity/nvo-shares-rise-on-strong-kickstart-for-wegoy-pill-in-us/cmUlCCgR4Bq">NVO Shares Rise On Strong Kickstart For Wegovy Pill In US: Retail Eyes Up To $110 As ‘Fair Value’</a></p><p><i>For updates and corrections, email newsroom[at]stocktwits[dot]com.</i></p>

In this photo illustration, the Novartis company logo is seen displayed on a smartphone screen. (Photo Illustration by Piotr Swat/SOPA Images/LightRocket via Getty Images)

NVS Stock Rises After FDA Grants Breakthrough Therapy Designation For Autoimmune Disorder Treatment

Novartis looks to submit data from its many trials of Ianalumab with health authorities starting in early 2026 for potential approval.

<ul class="summary-bullets"><li>The company added that the acquisition will embed Modella AI’s multi-modal foundation models and AI agents into AstraZeneca’s oncology research and development environment.</li><li>Separately, AstraZeneca announced that the first patient has been dosed in a late-stage trial evaluating Datroway compared to docetaxel in patients with certain types of lung cancer.</li></ul><p>Pharmaceutical giant AstraZeneca (AZN) has purchased Boston-based biomedical AI company Modella AI for an undisclosed sum, according to a statement from the startup on Tuesday.</p><p>Modella <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.businesswire.com/news/home/20260113561240/en/Modella-AI-Announces-Acquisition-by-AstraZeneca-to-Advance-AI-Driven-Oncology-RD-at-Global-Scale">said</a> that the buyout is aimed at expanding the two companies’ existing collaboration for advancing the application of artificial intelligence across the drugmaker’s cancer drug portfolio.</p><p>The company added that the acquisition will embed Modella AI’s multi-modal foundation models and AI agents into AstraZeneca’s oncology research and development environment. This would allow for the generation of new insights and allow for greater automation across workflows, the company said.</p><p>Shares of AZN traded marginally in the green at the time of writing.</p><h2 class="st-heading-2">Partnership To Acquisition</h2><p>Modella announced a multi-year deal with AstraZeneca in 2025 aimed at integrating its generative and agentic AI platform into AstraZeneca’s oncology research and development organization.</p><p>The collaboration was aimed at supporting efforts to accelerate clinical development and enhancing biomarker discovery.</p><h2 class="st-heading-2">First Patient Dosing In New Late-Stage Trial</h2><p>Separately, AstraZeneca announced earlier on Tuesday that the first patient has been dosed in a late-stage trial evaluating Datroway compared to docetaxel in patients with certain types of locally advanced or metastatic nonsquamous non-small cell lung cancer. Lung cancer is the most common cancer globally.</p><p>Datroway, meanwhile, is a cancer drug jointly developed and commercialized by AstraZeneca and Daiichi Sankyo.</p><h2 class="st-heading-2">How Did Stocktwits Users React?</h2><p>On Stocktwits, retail sentiment around AZN stock stayed within the ‘extremely bullish’ territory over the past 24 hours, while message volume stayed at ‘extremely high’ levels.</p><p>A Stocktwits user opined that AstraZeneca must try to acquire smaller drugmaker Omeros Corp.</p><p><stembedurl>https://www.stocktwits.com/resq1/message/641646825</stembedurl></p><p><a href="https://stocktwits.com/symbol/AZN">AZN stock</a> has gained 43% over the past 12 months.&nbsp;</p><p>Read More: <a href="https://stocktwits.com/news-articles/markets/equity/fund-manager-flags-concerns-about-tesla-dwindling-delivery-numbers-high-pe-ratio/cmUXXNkR4Ia">Fund Manager Flags Concerns About Tesla’s Dwindling Delivery Numbers, Notes High P/E Ratio</a></p><p><i>For updates and corrections, email newsroom[at]stocktwits[dot]com.</i></p>

The international biopharmaceutical company AstraZeneca office building in Shanghai, China on June 27, 2025. 

AstraZeneca Buys Boston-Based Startup In Fresh AI Push For Cancer Pipeline

Modella said that the buyout is aimed at expanding the two companies’ existing collaboration for advancing the application of artificial intelligence across the drugmaker’s cancer drug portfolio. 

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