SPDR Dow Jones Industrial Average ETF

SPDR S&P 500 ETF Trust

Invesco QQQ Trust Series 1

SSgA Active Trust - SPDR S&P 500 ETF Trust

The SPDR S&P 500 ETF Trust is trending amidst intense market volatility driven by escalating geopolitical tensions surrounding discussions of tariffs linked to Greenland. Community sentiment is sharply divided, with some investors anticipating a significant market downturn due to uncertainty and potential European retaliation, while others expect a swift "buy the dip" rebound, referencing past instances where tariff-related drops quickly reversed.

Bitcoin is the world's first decentralized cryptocurrency, created in 2009 by the pseudonymous Satoshi Nakamoto. It enables peer-to-peer electronic cash transactions without intermediaries like banks or governments, operating on a blockchain secured by Proof of Work mining and the SHA-256 cryptographic algorithm.   With a fixed supply cap of 21 million coins and programmatic halvings every four years that reduce miner rewards, Bitcoin is designed as a deflationary digital asset often called "digital gold." Its value stems from solving the double-spending problem without trusted intermediaries, creating the first truly scarce digital asset with censorship resistance and permissionless access that no government, corporation, or individual can control.  Bitcoin operates as a decentralized peer-to-peer network where transactions are recorded on a public ledger called the blockchain, distributed across thousands of computers globally. Transactions are grouped into blocks added approximately every 10 minutes through mining, where specialized computers compete to solve complex mathematical puzzles.   Bitcoin has achieved mainstream adoption through multiple vectors. The January 2024 SEC approval of 11 spot Bitcoin ETFs opened Bitcoin investment to traditional finance participants, and corporations like Strategy (formerly MicroStrategy) are using Bitcoin as a treasury reserve asset to protect against currency debasement, offering MSTR holders amplified exposure to Bitcoin.   The Bitcoin ecosystem continues to evolve with innovations like Ordinals, which emerged in January 2023 to enable NFT-like functionality directly on Bitcoin, and BRC-20 tokens, an experimental standard for creating fungible tokens using Ordinal inscriptions. BTCFi (Bitcoin Finance) represents emerging financial applications extending beyond Bitcoin's traditional role, with protocols like Babylon allowing Bitcoin holders to stake BTC to secure Proof of Stake chains.

Bitcoin

Bitcoin is trending due to heightened geopolitical tensions stemming from discussions between the U.S. and European nations regarding potential tariffs and Greenland. This situation has driven a risk-off sentiment across the crypto market, sparking community debates about Bitcoin's role as a safe haven asset, even as some investors see current price movements as a chance to accumulate.

SPDR Gold Trust - SPDR Gold Shares

SPDR Gold Shares ETF

SPDR Gold Shares (GLD) is trending significantly as renewed geopolitical tensions intensify, primarily driven by discussions around potential US tariffs on European countries concerning Greenland. This has sparked community debate regarding gold's role as a safe-haven asset, with many anticipating further upside amid broader uncertainty and concerns over currency debasement, while others caution about an overextended rally. The ongoing criticism of the Federal Reserve's independence adds another layer of market uncertainty supporting precious metals.

United States Commodity Funds LLC - United States Natural Gas Fund

United States Natural Gas Fund, LP

United States Natural Gas Fund ($UNG) is trending as an intensifying Arctic air invasion across large parts of the US is forecast to drive a significant surge in heating demand. The community is buzzing about a potential short squeeze, given extreme short interest and the sudden shift to frigid weather, though acknowledging the commodity's notorious volatility. This immediate weather catalyst is compounded by emerging long-term demand narratives surrounding AI data centers.

Intel Corp. engages in the design, manufacture, and sale of computer products and technologies. It delivers computer, networking, data storage, and communications platforms. The firm operates through the following segments: Client Computing Group (CCG), Data Center and AI (DCAI), Network and Edge (NEX), Mobileye, Accelerated Computing Systems and Graphics (AXG), Intel Foundry Services (IFS), and All Other. The CCG segment consists of platforms designed for notebooks, 2-in-1 systems, desktops, tablets, phones, wireless and wired connectivity products, and mobile communication components. The DCAI segment delivers solutions to cloud service providers and enterprise customers, along with silicon devices for communications service providers and high-performance computing customers. The NEX segment offers computing system solutions from inflexible fixed-function hardware to general-purpose compute, acceleration, and networking devices running cloud native software on programmable hardware. The Mobileye segment develops driving assistance and self-driving solutions. The AXG segment provides products and technologies designed to help customers solve the toughest computational problems. Its products include CPUs for high-performance computing and GPUs targeted for a range of workloads and platforms, from gaming and content creation on client devices to delivering media and gaming in the cloud, and the most demanding high-performance computing and AI workloads on supercomputers. The IFS segment refers to full stack solutions created from the foundry industry ecosystem. The All Other segment represents results from other non-reportable segments and corporate-related charges. The company was founded by Robert Norton Noyce and Gordon Earle Moore on July 18, 1968 and is headquartered in Santa Clara, CA.

Intel Corp.

Intel Corp

Intel is currently trending due to strong anticipation ahead of its upcoming earnings report, coupled with widespread speculation about major government foundry contracts and a potential significant client win for its advanced chip manufacturing. The community is actively discussing Intel's potential comeback and its perceived undervaluation compared to industry peers, driven by the broader narrative of domestic semiconductor manufacturing and surging demand for AI and server chips.

Invesco Capital Management LLC - Invesco QQQ Trust Series 1

The Invesco QQQ Trust is trending as renewed tariff threats and geopolitical statements from former President Trump regarding European allies and Greenland ignite market concern. While many anticipate a market dip, a strong 'buy the dip' sentiment persists among some traders, recalling past swift recoveries in the tech-heavy index.

ImmunityBio, Inc. is a clinical stage immunotherapy company. It develops next generation therapies that drive immunogenic mechanisms for defeating cancers and infectious diseases. The company's immunotherapy platform activates both the innate and adaptive immune systems to create long term immunological memory. ImmunityBio was founded by Patrick Soon-Shiong in 2014 and is headquartered in San Diego, CA.

ImmunityBio Inc

ImmunityBio is currently trending following recent international approvals for its cancer immunotherapies, notably in Saudi Arabia for lung cancer, alongside updated positive clinical study results. The community is enthusiastically discussing the potential of Anktiva to revolutionize cancer treatment and is vocal about perceived US FDA delays, which is fueling significant speculation around a short squeeze. Investors are expressing strong optimism regarding Dr. Soon-Shiong's strategic vision and the company's considerable growth trajectory.

Memecoin on Injective taken over by the community.

Nonja

NONJA CRYPTO is trending as a high-conviction meme on the Injective blockchain, currently energized by a governance proposal aiming to significantly boost $INJ's deflation rate and strong institutional interest. The community widely views $NONJA as a resilient and "unruggable" asset, boasting burned liquidity and an active base, making it the go-to leveraged play for Injective's anticipated growth during the next market cycle. Many believe $NONJA is well-positioned for outsized returns as the underlying chain continues to mature and gain recognition.

VanEck ETF Trust - VanEck Junior Gold Miners ETF

VanEck Junior Gold Miners ETF

The VanEck Junior Gold Miners ETF ($GDXJ) is trending as gold and silver prices surge, with the community largely viewing junior miners as a leveraged play on this rally. Many anticipate significant upside and undervaluation in the sector, driven by global economic uncertainties and expectations of continued demand for precious metals.

Coinbase Global, Inc. engages in the provision of a trusted platform that serves as a compliant on-ramp to the onchain economy and enables users to engage in a wide variety of activities with their crypto assets in both proprietary and third-party product experiences enabled by access to decentralized applications. It offers consumers primary financial account for the cryptoeconomy, institutions a full-service prime brokerage platform with access to deep pools of liquidity across the crypto marketplace, and developers a suite of products granting access to build onchain. The company was founded by Brian Armstrong and Fred Ernest Ehrsam in May 2012 and is headquartered in New York, NY.

Coinbase Global Inc - Ordinary Shares - Class A

Coinbase Global Inc

Coinbase is trending due to significant uncertainty surrounding the Digital Asset Market Clarity Act, after its CEO withdrew support over concerns about stablecoin rewards and other provisions, leading to the Senate postponing a key hearing. Community discussion reflects frustration with the stock's underperformance despite broader crypto movements, with many debating if the CEO's stance is a strategic long-term win or a short-term blow for vital revenue streams.

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Nifty 50

Nifty Bank

Reliance Industries Ltd.

Zomato Ltd.

Tata Consultancy Services

Tata Motors Ltd.

HDFC Bank Ltd.

ITC Ltd.

Adani Enterprises Ltd

Axis Bank Ltd

Bajaj Finance Ltd

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SPDR S&P 500 ETF

Apple Inc.

Tesla Inc

Microsoft Corporation

NVIDIA Corp

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Galmed Announces Acceptance of a Late-Breaking Abstract to be Presented at HEP-DART 2025 Meeting

Galmed Announces Acceptance of a Late-Breaking Abstract to be Presented at HEP-DART 2025 Meeting Galmed Announces Acceptance of a Late-Breaking Abstract to be Presented at HEP-DART 2025 Meeting PR...

Galmed Announces Grant of New Use Patents for the combination of Aramchol and Madrigal Pharmaceuticals' Rezdiffra (Resmetirom) for MASH

Galmed Announces Grant of New Use Patents for the combination of Aramchol and Madrigal Pharmaceuticals' Rezdiffra (Resmetirom) for MASH Galmed Announces Grant of New Use Patents for the combination...

Galmed Issues CEO Letter to Shareholders

Galmed Issues CEO Letter to Shareholders Galmed Issues CEO Letter to Shareholders PR Newswire TEL AVIV, Israel, Dec. 1, 2025 TEL AVIV, Israel, Dec. 1, 2025 /PRNewswire/ -- Galmed Pharmaceuticals Ltd...

Galmed Pharmaceuticals Reports Third Quarter 2025 Financial Results and Provides Business Update

Galmed Pharmaceuticals Reports Third Quarter 2025 Financial Results and Provides Business Update Galmed Pharmaceuticals Reports Third Quarter 2025 Financial Results and Provides Business Update PR...

Galmed Announces Meaningful Top Line Results from AM-001 Study of Aramchol Meglumine

Galmed Announces Meaningful Top Line Results from AM-001 Study of Aramchol Meglumine Galmed Announces Meaningful Top Line Results from AM-001 Study of Aramchol Meglumine PR Newswire RAMAT-GAN...

<ul class="summary-bullets"><li>Galmed reported new data showing that its Aramchol–Stivarga–Metformin combination improved tumor cell killing in GI cancer models.</li><li>The company plans to begin Phase 1b trials in early 2026 as key Stivarga patents near expiration.</li><li>Stocktwits users focused on possible dilution, SEC filings, and the timing of upcoming earnings.</li></ul>Galmed Pharmaceuticals shares&nbsp;rose on Monday, following four sessions of losses, after the company reported top-line results showing that a three-drug combination of Aramchol, Stivarga and Metformin significantly improved tumor-cell killing in gastrointestinal cancers.The stock closed up 1% at $1.05 before slipping 4.6% in after-hours trading.<h2 class="st-heading-2">Top-Line Results Highlight Triple-Drug Effect</h2>Galmed said the regimen of Aramchol, Stivarga and Metformin demonstrated a significant synergistic effect, improving tumor-cell killing both in vivo and in vitro. The company said the combination&nbsp;could be developed as a fixed-dose therapy that could strengthen the effect of Stivarga, Bayer’s top-selling cancer drug.According to the company, the combination may serve as a life-cycle IP strategy for Stivarga as key patents expire in Europe in August 2028 and in the U.S. in July 2032. Two new U.S. patent applications have been submitted.Galmed said the Aramchol-Stivarga combination is expected to enter Phase 1b clinical trials in early 2026 for metastatic colorectal cancer, hepatocellular carcinoma and cholangiocarcinoma, with a planned expansion cohort including Metformin.<h2 class="st-heading-2">Study Builds On Prior Findings</h2>An earlier May study reported that Aramchol enhanced the efficacy of regorafenib in gastrointestinal cancer models. In that study, Aramchol&nbsp;enhanced the breakdown of cellular material triggered by regorafenib and affected several cell-signaling pathways linked to tumor growth. The combination also reduced tumor growth in liver cancer models without harming normal tissue.The newly announced results include additional data on&nbsp;the use of Aramchol in combination with regorafenib and Metformin. The study reported that Aramchol showed anti-tumor activity on its own and when&nbsp;combined with the other two drugs, and that the three-drug combination produced a reinforcing effect, supporting further development as a combined treatment.<h2 class="st-heading-2">Clinical Path Ahead</h2>Allen Baharaff said a fixed-dose combination with Aramchol “could potentially become a life-cycle IP strategy for regorafenib to help delay the generic competition.”Baharaff said the company is preparing to initiate its Phase 1b study at VCU Massey Comprehensive Cancer Center in early 2026. He added that positive findings could support accelerated development of Aramchol across three gastrointestinal cancer indications and expand the company’s pipeline.<h2 class="st-heading-2">Stocktwits Users Flag Possible Dilution</h2>On Stocktwits, retail sentiment for Galmed was ‘extremely bullish’ amid a 12,950% surge in 24-hour message volume.<figure class="image"><img style="aspect-ratio:968/143;" src="https://news.stocktwits-cdn.com/glmd_ss_jpg_a183d03fe6.webp" alt="glmd ss.jpg" width="968" height="143"><figcaption>GLMD sentiment and message volume as of November 17 | Source: Stocktwits</figcaption></figure>One user said, “Now let's wait for SEC filing. Crossed my fingers. I will tell you, if no dilution SEC is filed today after market close or before market opens, then get ready for another run and this would be epic run”<stembedurl>https://stocktwits.com/madan_shatri/message/636516948</stembedurl>Another user commented that they anticipated earnings “any day” and suggested the stock might attempt “a runup” before a potential offering.<stembedurl>https://stocktwits.com/Jonsie/message/636511939</stembedurl>Galmed’s stock has declined 67% so far in 2025.For updates and corrections, email newsroom[at]stocktwits[dot]com.

 In this photo illustration, the Galmed Pharmaceuticals logo is displayed on the screen of a tablet. (Photo Illustration by Sheldon Cooper/SOPA Images/LightRocket via Getty Images)

Galmed Pharmaceuticals Stock Snaps 4-Day Losing Streak On Triple-Drug Cancer Breakthrough — Retail Sees Dilution Risks

Galmed reported new data showing that its Aramchol–Stivarga–Metformin combination improved tumor cell killing in GI cancer models.

Equity

Galmed Announces Top-line Results in Oncology MoA Studies: A 3-drug combination of Aramchol, Stivarga and Metformin Significantly Enhanced GI Tumor Cells, Killing In-vivo and In-vitro

Galmed Announces Top-line Results in Oncology MoA Studies: A 3-drug combination of Aramchol, Stivarga and Metformin Significantly Enhanced GI Tumor Cells, Killing In-vivo and In-vitro Galmed...

Galmed Pharmaceuticals Reports Second Quarter 2025 Financial Results and Provides Business Update

Galmed Pharmaceuticals Reports Second Quarter 2025 Financial Results and Provides Business Update Galmed Pharmaceuticals Reports Second Quarter 2025 Financial Results and Provides Business Update PR...

Galmed Pharmaceuticals (GLMD) shares rose sharply on Tuesday after the company reported positive preclinical data showing that its experimental drug Aramchol enhances the effectiveness of Regorafenib in liver and colon cancer models.Following the announcement, Galmed's stock rose by 10.6%, closing at $1.46 per share.&nbsp;According to the company, Aramchol improved the anti-tumor activity of Regorafenib — a multi-kinase inhibitor approved for liver and colorectal cancers — in both in-vitro and in-vivo settings.&nbsp;The combination also activated ATM and AMPK pathways while inhibiting mTORC1 and mTORC2, mechanisms known to play roles in cancer cell survival.Aramchol was also shown to work in combination with other kinase inhibitors like Sorafenib and Lenvatinib, though Regorafenib exhibited the strongest synergistic effects.&nbsp;The dual treatment suppressed tumor growth in hepatoma models without causing toxicity to normal tissues, the company said.Retail sentiment spiked following the update.&nbsp;On Stocktwits, message volume surged 4,480% over 24 hours, with sentiment marked as ‘extremely bullish.’Some retail investors suggested the stock could double from a previous $1.31 entry level.&nbsp;<stembedurl>https://stocktwits.com/debbiekatz/message/613719065</stembedurl>Others speculated the price could climb to the $2.50–$3.00 range, reflecting confidence ahead of the next trading session.<stembedurl>https://stocktwits.com/ZCOCSTOCK/message/613738896</stembedurl>Galmed said it expects to initiate a Phase 1b trial of Aramchol in combination with Regorafenib by the fourth quarter of 2025.The oncology update comes on the heels of another strategic development.&nbsp;Last week, Galmed signed a binding term sheet with Entomus s.r.o. for the licensing of a proprietary Self-Emulsifying Drug Delivery System (SEDDS) formulation.&nbsp;The technology enables sublingual absorption of peptides such as GLP-1, a key target in metabolic disorders.&nbsp;A definitive agreement outlining milestones and royalty terms is expected within 90 days.Shares of Galmed have fallen 56% so far this year.For updates and corrections, email newsroom[at]stocktwits[dot]com.

RBC said Medicaid spending was politically harder to unwind than the Journal suggested, adding that many small and rural hospitals depend on these payments to stay afloat. | Image source: Getty Images

Galmed Pharma Shares Jump 10% On Cancer Drug Data: Retail Traders Turn ‘Extremely Bullish’

The company reported that Aramchol, its experimental liver drug, enhanced Regorafenib’s anti-tumor effects without causing toxicity in preclinical models.

Galmed Pharmaceuticals Ltd. is a clinical-stage drug development biopharmaceutical company, which engages in the development of oral therapy for the treatment of non-alcoholic steato-hepatitis (NASH). Its product candidate, Aramchol, is a synthetic fatty acid-bile acid conjugate molecule for the oral treatment of NASH in patients who are overweight or obese and have prediabetes or type II diabetes mellitus. The company was founded by Allen Baharaff and Tuvia Gilat in 2000 and is headquartered in Tel Aviv, Israel.

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