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Avalanche is a high throughput smart contract blockchain&nbsp;platform. Validators secure the network through a proof-of-stake consensus protocol. It is said to be fast, low cost, and environmental friendly.

Avalanche

Avalanche is currently facing intense selling pressure and negative sentiment as investors express frustration over prolonged stagnant price action and its consistent underperformance compared to other assets. The community is actively debating the project's long-term utility versus its speculative nature, while many are focused on the impact of upcoming legislative developments and potential accumulation opportunities during this period of high volatility.

ASML Holding NV engages in the development, production, marketing, sales, upgrading and servicing of advanced semiconductor equipment systems. It includes lithography, metrology and inspection systems. The company was founded on April 1, 1984 and is headquartered in Veldhoven, the Netherlands.

ASML Holding NV - New York Shares

ASML Holding NV

ASML Holding NV is currently trending as investors weigh strong AI-driven demand and a record backlog against potential headwinds from new U.S. export controls and broader semiconductor market volatility. Community sentiment remains mixed, with bullish long-term investors pointing to the company's EUV lithography monopoly, while others express caution regarding valuation premiums and geopolitical risks impacting the global supply chain.

The Goldman Sachs Group, Inc. engages in the provision of financial services. It operates through the following business segments: Global Banking and Markets, Asset and Wealth Management, and Platform Solutions. The Global Banking and Markets segment includes investment banking, global investments, and equity and debt investments. The Asset and Wealth Management segment relates to the direct-to-consumer banking business which includes lending, deposit-taking, and investing. The Platform Solutions segment includes consumer platforms such as partnerships offering credit cards and point-of-sale financing, and transaction banking. The company was founded by Marcus Goldman in 1869 and is headquartered in New York, NY.

Goldman Sachs Group, Inc.

Goldman Sachs is currently at the center of market attention as investors monitor its exposure to private credit stress and potential shifts in bank capital requirements. The community is actively debating its valuation relative to growth prospects, with many traders closely watching technical levels ahead of the upcoming earnings cycle and broader sentiment on the banking sector.

Back in 2011, long before “crypto Twitter”, NFTs, or VC-backed chains existed, users of the BitcoinTalk forum came up with a new currency - not to launch a network, but to make fun of btc.... and so: The first memecoin/memecurrency was born.  On May 23, 2011, a Something Awful poster cracked, “Has anyone called them buttcoins yet?”. It was sophomoric and perfect. Within weeks the gag metastasized into Buttcoin.org, a parody blog that described a “peer to peer butt” economy while cataloging mining fiascos, exchange blowups, and MLM-adjacent “innovations”.

Buttcoin

Buttcoin is trending as the community leans into its legacy as a long-standing parody project, with supporters highlighting its early origins and the goal of achieving billion-dollar status. Discussion centers on the project's shift from a joke to an on-chain asset, with the community actively comparing its potential to the broader cryptocurrency market while leveraging the humor inherent in its branding.

Maulcoin

Maulcoin is trending as its community aggressively rallies behind the project's organic growth and 'join the dark side' branding, with members actively pushing for social engagement and new listings to drive the next wave of price appreciation. Investors are heavily focused on holding through dips and hitting specific market cap milestones that trigger community-wide airdrops, highlighting a strong collective sentiment centered on long-term accumulation rather than short-term gains.

Algorand is a scalable, secure, and decentralized digital currency and smart contract platform. Its protocol uses a variation of Proof-of-Stake (PoS) called Pure PoS (PPoS) to secure the network and reach consensus on block production. Developers can build decentralized applications (dApps) using familiar programming languages, including Python, which Algorand supports natively. Its infrastructure enables various use cases, including payment systems, digital identity solutions, supply-chain tracking, and financial services. The protocol's architecture allows for tokenization of assets and the development of smart contracts, while its technical specifications support both retail users seeking basic transaction capabilities and enterprises requiring more, complex, blockchain solutions.

Algorand

Algorand is seeing heightened social engagement as the community reacts to a recent Google research paper that cites its protocol as a benchmark for quantum-resistant security, while investors remain split between long-term optimism regarding its enterprise utility and frustration over extended price volatility.

Bitcoin is the world's first decentralized cryptocurrency, created in 2009 by the pseudonymous Satoshi Nakamoto. It enables peer-to-peer electronic cash transactions without intermediaries like banks or governments, operating on a blockchain secured by Proof of Work mining and the SHA-256 cryptographic algorithm.   With a fixed supply cap of 21 million coins and programmatic halvings every four years that reduce miner rewards, Bitcoin is designed as a deflationary digital asset often called "digital gold." Its value stems from solving the double-spending problem without trusted intermediaries, creating the first truly scarce digital asset with censorship resistance and permissionless access that no government, corporation, or individual can control.  Bitcoin operates as a decentralized peer-to-peer network where transactions are recorded on a public ledger called the blockchain, distributed across thousands of computers globally. Transactions are grouped into blocks added approximately every 10 minutes through mining, where specialized computers compete to solve complex mathematical puzzles.   Bitcoin has achieved mainstream adoption through multiple vectors. The January 2024 SEC approval of 11 spot Bitcoin ETFs opened Bitcoin investment to traditional finance participants, and corporations like Strategy (formerly MicroStrategy) are using Bitcoin as a treasury reserve asset to protect against currency debasement, offering MSTR holders amplified exposure to Bitcoin.   The Bitcoin ecosystem continues to evolve with innovations like Ordinals, which emerged in January 2023 to enable NFT-like functionality directly on Bitcoin, and BRC-20 tokens, an experimental standard for creating fungible tokens using Ordinal inscriptions. BTCFi (Bitcoin Finance) represents emerging financial applications extending beyond Bitcoin's traditional role, with protocols like Babylon allowing Bitcoin holders to stake BTC to secure Proof of Stake chains.

Bitcoin

Bitcoin is currently facing heightened volatility and bearish sentiment as traders react to the breakdown of US-Iran negotiations and ongoing uncertainty surrounding the Strait of Hormuz. While some market participants anticipate a potential capitulation event and further downside, others remain focused on long-term accumulation, highlighting a significant divergence between technical sell-signals and institutional conviction.

S&P Global, Inc. engages in the provision of transparent and independent ratings, benchmarks, analytics, and data to the capital and commodity markets worldwide. It operates through the following segments: Market Intelligence, Ratings, Mobility, Indices, and Engineering Solutions. The Market Intelligence segment provides multi-asset-class data and analytics integrated with purpose-built workflow solutions. The Ratings segment is involved in credit ratings, research, and analytics, offering investors and other market participants information, ratings, and benchmarks. The Mobility segment offers solutions serving the full automotive value chain including vehicle manufacturers, automotive suppliers, mobility service providers, retailers, consumers, and finance and insurance companies. The Engineering Solutions segment engages in advanced knowledge discovery technologies, research tools, and software-based engineering decision engines to advance innovation, maximize productivity, improve quality, and reduce risk. The company was founded by James H. McGraw and John A. Hill in 1917 and is headquartered in New York, NY.

S&P Global Inc

S&P Global is currently drawing investor attention as it partners with major financial institutions to launch a new credit default swap index designed to hedge against default risks in the private credit and banking sectors. Market participants are closely watching these developments, with community discussions heavily focused on the company's role as a resilient, institutional-grade compounder that provides critical infrastructure and downside protection in an uncertain macro environment.

Ethereum is a global, open-source platform for decentralized applications. In other words, it is a decentralized blockchain platform that enables developers to build and deploy smart contracts and applications without central authority control. Unlike Bitcoin, which primarily functions as digital currency, Ethereum operates as a programmable global computer where developers can create any type of decentralized service.   The platform hosts over $14 billion in DeFi applications with hundreds of thousands of active users across financial protocols, NFT marketplaces, and gaming platforms. Its transition to Proof of Stake in September 2022 reduced energy consumption by over 99%, addressing environmental concerns while strengthening network security.  The network operates through thousands of independent validator nodes that process transactions and execute smart contracts on the Ethereum Virtual Machine. Smart contracts are self-executing programs written in Solidity that automatically carry out agreements when conditions are met, eliminating intermediaries like banks or brokers.   Validators stake ETH as collateral to propose and validate blocks, earning rewards for honest participation while facing penalties for malicious behavior. The EIP-1559 upgrade introduced a dynamic base fee mechanism that burns ETH with each transaction, creating deflationary pressure during high network activity when more ETH is burned than issued to validators.  Vitalik Buterin proposed Ethereum in 2013, but seven co-founders helped build it, including Gavin Wood who created Solidity and the EVM technical specification, and Joseph Lubin who founded ConsenSys. The project launched in July 2015 after raising over $18 million through crowdfunding, quickly becoming the largest blockchain developer community. Major milestones include the 2020 Beacon Chain launch, the 2021 London hard fork implementing fee burning, and the 2022 Merge to Proof of Stake.   Ether (ETH) serves multiple functions: paying transaction fees (gas), staking to secure the network and earn 3-5% annual yields, serving as collateral in DeFi protocols, and purchasing NFTs and digital assets. The asset is increasingly adopted by traditional institutions, with publicly traded companies adding ETH to corporate treasuries to generate staking yields while maintaining blockchain exposure, and in 2024, the SEC approved spot Ethereum ETFs, allowing traditional investors to gain exposure through conventional brokerage accounts.  Ethereum's roadmap focuses on dramatically increasing transaction capacity to over 100,000 per second, reducing confirmation times, and enhancing decentralization while maintaining security against future threats like quantum computing.

Ethereum

Ethereum is facing intense volatility as the market digests the fallout from stalled negotiations in the Strait of Hormuz, with community sentiment deeply divided between fears of further geopolitical escalation and optimism for a broader crypto recovery. While some traders are bracing for a potential downturn due to rising energy costs and macro uncertainty, others are actively tracking ETF inflows and technical indicators for signs of a sustained breakout.

Fortuna Mining Corp. engages in the exploration, extraction and processing of precious and base metal in Latin America. It operates through the following segments: Minera Bateas S.A.C (Bateas), Compania Minera Cuzcatlan S.A. de C.V. (Cuzcatian), Mansfield Minera S.A. (Mansfield), and Corporate. The Beates segment operates the Caylloma silver, lead, and zinc mine. The Cuzcatlan segment handles the San Jose silver-gold mine. The Mansfield segment constructs the Lindero mine. The Corporate segment represents the corporate stewardship. The company was founded by Jorge Alberto Ganoza Durant, Simon T. P. Ridgway, and Mario David Szotlender on September 4, 1990 and is headquartered in Vancouver, Canada.

Fortuna Mining Corp.

Fortuna Silver Mines Inc.

Fortuna Mining is attracting investor interest as shareholders look ahead to earnings, driven by optimism over record gold production, high metal prices, and a strong balance sheet. The community is actively discussing the companys share buyback initiatives and potential undervaluation compared to peers, while navigating frustration over broader volatility in the mining sector.

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<ul class="summary-bullets"><li>Kazia stated that in murine triple-negative breast cancer preclinical models, NDL2 reduced primary tumor volume by 49% as monotherapy.</li><li>In combination with the anti-PD-1 therapy, the treatment reduced the volume of the primary tumor by 73%.</li><li>In patients with lung metastases, Kazia stated that NDL2, combined with anti-PD-1 therapy, reduced the primary tumor’s volume by 50%.</li></ul><p>Kazia Therapeutics Inc.’s (KZIA) shares rose more than 6% in Friday’s pre-market trade after the company announced new preclinical and translational data for NDL2, a protein degrader.</p><p>The Sydney, Australia-based oncology-focused pharmaceutical company stated that across multiple preclinical models and patient-derived samples, NDL2 demonstrated reversal of immune exhaustion, suppression of metastatic biology, and enhanced anti-tumor activity. This includes the combination of NDL2 with anti-PD-1 therapy, which uses monoclonal bodies such as nivolumab or pembrolizumab to block the PD-1 protein on T-cells.</p><p>Retail sentiment on Stocktwits around&nbsp;<a href="https://stocktwits.com/symbol/KZIA">Kazia Therapeutics</a> was in the ‘bullish’ territory at the time of writing, while message volume was at ‘high’ levels.</p><h2 class="st-heading-2">Highlights Of New NDL2 Data</h2><p>Kazia stated that in murine triple-negative breast cancer (TNBC) preclinical models, NDL2 reduced primary tumor volume by 49% as monotherapy. In combination with the anti-PD-1 therapy, the treatment reduced the volume of the primary tumor by 73%.</p><p>In patients with lung metastases, Kazia stated that NDL2, combined with anti-PD-1 therapy, reduced the primary tumor’s volume by 50%.</p><p>The company added that no toxicity or hemolysis was observed, while noting that the immune checkpoint function at the cell surface was preserved, and the plasma stability was favorable.</p><h2 class="st-heading-2">What Is NDL2 Aimed At?</h2><p>Kazia is currently developing the NDL2 protein degrader to selectively eliminate nuclear PD-L1 (Programmed Death-Ligand 1).</p><p>PD-L1 is a protein found on the surface of many cancer cells as well as some normal cells. The protein helps these cells evade the immune system.</p><p><a href="https://stocktwits.com/symbol/KZIA">KZIA stock</a> is down 6% year-to-date and 12% over the past 12 months.</p><p>Also See:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/sofi-stock-rises-after-sofi-technologies-reports-1b-quarterly-revenue-first-time/cmySKHPR4ST"><strong>SOFI Stock Rises Pre-Market After SoFi Technologies Reports $1B Quarterly Revenue For The First Time</strong></a></p><p><i>For updates and corrections, email newsroom[at]stocktwits[dot]com.</i></p>

Representative image of a trending stock chart.

KZIA Stock Is Rising Today — What Does Its Data For Nuclear PD-L1 Degrader Show?

Kazia stated that across multiple preclinical models and patient-derived samples, NDL2 demonstrated reversal of immune exhaustion, suppression of metastatic biology, and enhanced anti-tumor activity.

Equity

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Kazia Therapeutics Reports Encouraging Preliminary Clinical Responses in Ongoing Phase 1b Study of Paxalisib in Late-Stage Metastatic Triple-Negative Breast Cancer

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Kazia Therapeutics Highlights New Clinical and Translational Findings Demonstrating Paxalisib's Ability to Reinvigorate Anti-Tumor Immunity Across Multiple Advanced Breast Cancer Populations including TNBC and HER2+

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What's Going On With Cancer Firm Kazia Therapeutics

Kazia announced a private placement of $50 million in equity securities. Proceeds will fund clinical development and extend cash runway.read more...

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<ul class="summary-bullets"><li>The patient remains on therapy and under active clinical monitoring, the company said.</li><li>In October, Kazia had announced that it observed an 86% reduction in tumor burden after only three weeks of treatment in the same patient.</li><li>Kazia also raised concerns on Tuesday regarding a potential suspension or delisting of its shares from the Nasdaq.</li></ul><p>Shares of cancer drug developer Kazia Therapeutics Limited (KZIA) were in the spotlight on Wednesday after the company said that a stage IV triple-negative breast cancer patient treated with a combination of its lead program Paxalisib with Pembrolizumab and standard chemotherapy has achieved an initial immune-complete response.</p><p>An immune-complete response means the complete disappearance of all signs of cancer following immunotherapy. It is also known as complete remission.</p><p>KZIA shares traded 42% higher on Wednesday morning at the time of writing.</p><h2 class="st-heading-2">Data And Takeaways</h2><p>As per Kazia, complete responses in stage IV metastatic TNBC are exceedingly uncommon and may suggest enhanced biological activity of the combination regimen, warranting continued follow-up.</p><p>In October, Kazia had announced that it observed an 86% reduction in tumor burden after only three weeks of treatment in the same patient. After about three months of therapy, a scan performed demonstrated complete metabolic resolution of all previously identified lesions, consistent with an initial immune-complete response, the company said.</p><p>The patient remains on therapy and under active clinical monitoring, the company <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.prnewswire.com/news-releases/kazia-therapeutics-achieves-initial-icr-immune-complete-response-in-metastatic-tnbc-and-delivers-q4-business-update-with-breakthroughs-across-breast-cancer-immuno-oncology-and-gbm-regulatory-strategy-302618635.html">added</a>. Kazia now plans to conduct a follow-up scan to confirm the initial scan.</p><h2 class="st-heading-2">Executive Commentary</h2><p>"Observing an initial complete response in a patient with metastatic triple-negative breast cancer is an extremely encouraging clinical finding," said CEO John Friend.</p><p>Paxalisib was licensed from Genentech in late 2016 and is being developed to treat multiple forms of cancer. The company now intends to request a meeting with the U.S. Food and Drug Administration to discuss the overall survival Paxalisib findings from its completed clinical studies and to discuss the elements needed for an application submission for Paxalisib in newly diagnosed glioblastoma.</p><h2 class="st-heading-2">Delisting Concerns</h2><p>Kazia on Tuesday also raised concerns about a potential suspension or delisting of its shares from Nasdaq, as it is not in compliance with certain listing rules. The company said it intends to request a hearing before a Nasdaq panel in a timely manner to stay any suspension or delisting action pending the outcome of the hearing.</p><p>The company is now also evaluating corporate and market-based options to regain compliance.</p><h2 class="st-heading-2">How Did Stocktwits Users React?</h2><p>On Stocktwits, retail sentiment around <a href="https://stocktwits.com/symbol/KZIA">KZIA stock</a> jumped from ‘bearish’ to ‘extremely bullish’ territory over the past 24 hours, while message volume rose from ‘low’ to ‘extremely high’ levels.</p><figure class="image"><img style="aspect-ratio:585/56;" src="data:image/png;base64,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" width="585" height="56" alt="KZIA's Sentiment Meter and Message Volume as of 9:23 a.m. ET on Nov. 19, 2025 | Source: Stocktwits"><figcaption>KZIA's Sentiment Meter and Message Volume as of 9:23 a.m. ET on Nov. 19, 2025 | Source: Stocktwits</figcaption></figure><p>KZIA stock is down by 8% this year and by about 71% over the past 12 months.</p><p>Also See: <a href="https://stocktwits.com/news-articles/markets/equity/alkermes-to-acquire-avadel-for-up-to-2.37-billion-after-lundbeck-proposal/cLPoIyoREB2">Race For Avadel Heats Up: Alkermes Raises Offer To Secure $2.37B Deal After Lundbeck Challenge</a></p><p><i>For updates and corrections, email newsroom[at]stocktwits[dot]com</i></p>

Rising stock market chart on a trading board background.

KZIA Stock Soars After Stage IV Cancer Patient Shows Initial Complete Remission On Its Drug Combination

Kazia now plans to conduct a follow-up scan to confirm the initial scan. 

Kazia Therapeutics Ltd. is an oncology-focused biotechnology company, which engages in the business of pharmaceutical drug development. It focuses on its Paxalisib program, which is designed to treat brain cancer. The company was founded by Graham Edmund Kelly in March 1994 and is headquartered in Sydney, Australia.

Current Price	$8.82
Prev Close	$9.10
Open	$9.10
Dividend Yield	0.00%
50-Day Moving Average	$7.23
Beta	1.26
Avg. Volume	134,147.20
PE Ratio	-1.29

52-Week High	$17.40
52-Week Low	$2.86
Market Capitalization	$99.98M
EPS (Annual)	-$12.23
Price to Book	3.23
Revenue Per Employee	N/A

KZIA
Kazia Therapeutics

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KZIAKazia Therapeutics