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BioNTech SE operates as immunotherapy company, which engages therapies for cancer and other serious diseases. Its product pipeline include BNT162b2, BNT161, BNT164, FixVac, iNeST, RiboMabs, CAR-T Cells, TCRs and Next-Gen CP Immunomodulators. The company was founded by Christopher Huber, Oezlem Tuereci, and Ugur Sahin on June 2, 2008 and is headquartered in Mainz, Germany.

BioNTech SE - ADR

Attention centers on BioNTechs Nov. 3 earnings and pipeline update, with traders weighing oncology readouts and whether management can convert its pipeline into meaningful progress. Bulls point to ESMO data and potential pipeline guidance, while skeptics cite mixed or failed trial results and leadership-transition concerns.

Twilio, Inc. engages in the development of communications software, cloud-based platforms, and services. It operates through Twilio Communications and Twilio Segments. The Twilio Communications segment includes the platforms Messaging and Voice. The Twilio Segment involves Segment, Engage, Flex, Email, and others. The company was founded by John Wolthuis, Jeffery G. Lawson, and Evan Cooke in March 2008 and is headquartered in San Francisco, CA.

Twilio Inc - Ordinary Shares Class A

Twilio Inc

Twilios Q3 results beat expectations and its full-year outlook rose, but a softer Q4 organic-growth outlook signaling deceleration overshadowed the positives and fueled a sharp selloff. Traders are split between viewing the drop as an overreaction to guidance and seeing it as a justified repricing amid slower messaging growth.

Novo Nordisk A/S is a global healthcare company, which engages in the discovery, development, manufacturing and marketing of pharmaceutical products. It operates through the Diabetes and Obesity Care and Rare Disease segments. The Diabetes and Obesity Care segment includes diabetes, obesity, cardiovascular, and emerging therapy areas. The Rare Disease segment refers to rare blood disorders, rare endocrine disorders, and hormone replacement therapy. The company was founded by Harald Pedersen and Thorvald Pedersen in 1923 is headquartered in Bagsværd, Denmark.

Novo Nordisk - ADR

Novo Nordisk A/S

Novos upcoming Q3 report is the main near-term focus, with traders watching whether oral Wegovy demand and company guidance can improve sentiment amid pressure from Eli Lillys obesity-drug competition. Some expect a stronger report to support a recovery, while others doubt positive results will overcome concerns about management execution and the stocks prolonged weakness.

Amgen, Inc. is a biotechnology company, which engages in the discovery, development, manufacture, and marketing of human therapeutics. The company was founded by William K. Bowes, Jr., Franklin Pitcher Johnson, Jr., George B. Rathmann, and Joseph Rubinfeld on April 8, 1980 and is headquartered in Thousand Oaks, CA.

AMGEN Inc.

Amgens positive Phase 3 IMDELLTRAIMFINZI lung-cancer results, which showed a lower risk of death, are fueling bullish attention alongside fresh highs and strong momentum. Traders are also watching the upcoming earnings report and a Sjgrens disease data update, with some interpreting put activity as hedging rather than outright bearishness.

Icahn Enterprises LP is a holding company. It operates through the following segments: Investment, Automotive, Energy, Food Packaging, Real Estate, Home Fashion, Pharma, and Holding Company. The Investment segment consists of various private investment funds. The Automotive segment holds ownership in Icahn Automotive Group, LLC. The Energy segment refers to petroleum refining and marketing businesses. The Food Packaging segment involves the production and sale of cellulosic, fibrous, and plastic casings for the processed meat and poultry industry. The Real Estate segment offers rental real estate, property development, and resort activities. The Home Fashion segment deals with manufacturing, sourcing, marketing, distributing, and selling home fashion consumer products. The Pharma segments operate through Vivus, Inc., a specialized pharmaceutical company. The Holding Company segment manages acquisition and investment in operating businesses. The company was founded on February 17, 1987 and is headquartered in Sunny Isles Beach, FL.

Icahn Enterprises L P - Unit

Icahn Enterprises, L.P.

IEP is drawing attention ahead of its earnings call, with traders focused on the distributions sustainability and an unusual overlap in timing with CVR Energys results. The falling share price has fueled fears of a distribution cut and questions about losses, debt and hedging, while some holders argue CVR Energy and asset-sale proceeds could support the partnership.

Rolls-Royce Holdings Plc designs, develops, manufactures, and services integrated power systems for use in the air, on land, and at sea. The company operates its business through following segments: Civil Aerospace, Power Systems, and Defense. The Civil Aerospace segment offers commercial aero engines and aftermarket services. The Power Systems segment includes engines, power systems and nuclear systems for civil power generation. The Defense segment consists of military aero engines, naval engines, submarines and aftermarket services. The company was founded in March 1906 and is headquartered in London, the United Kingdom.

Rolls-Royce Holdings Plc - ADR

Rolls-Royces sharp pullback is prompting debate over whether oil and jet-fuel concerns, broader market weakness, and aerospace-sector signals are driving the selling despite no widely cited deterioration in company fundamentals. Traders also point to the UK government-backed narrowbody engine development programme as a long-term positive, though some are frustrated that it has not offset the recent weakness.

Cameco Corp. engages in the provision of uranium. It operates through the following segments: Uranium and Fuel Services. The Uranium segment is involved in the exploration for, mining, milling, purchase, and sale of uranium concentrate. The Fuel Services segment deals with the refining, conversion, and fabrication of uranium concentrate and the purchase and sale of conversion services. The company was founded in 1988 and is headquartered in Saskatoon, Canada.

Cameco Corp.

Cameco shares are under pressure after lower Q3 results and narrower 2026 production guidance, with traders also pointing to Cigar Lake production concerns and heavy bearish options activity. The selloff has prompted debate between near-term worries about operations and valuation and the longer-term uranium-demand and nuclear-growth thesis.

Roblox Corp. engages in the provision of online gaming services. Its platform consists of Roblox Client, Roblox Studio, and Roblox Cloud. Roblox Client is an application that allows users to explore 3D digital worlds. Roblox Studio is the toolset that allows developers and creators to build, publish, and operate 3D experiences and other content accessed with Roblox Client. Roblox Cloud includes the services and infrastructure that power the human co-experience platforms. The company was founded by Erik Cassel and David B. Baszucki in March 2004 and is headquartered in San Mateo, CA.

Roblox Corporation - Ordinary Shares - Class A

Roblox Corp.

Robloxs quarterly report and weaker-than-expected outlook for holiday-quarter bookings, alongside a daily-user miss, triggered a sharp selloff despite some headline results beating estimates. Traders are split between viewing the drop as a buying opportunity near support and warning that slowing engagement and bookings point to weaker growth.

Karman Holdings, Inc. engages in the design, testing, manufacturing, and sale of dependable missile systems. It offers Payload Protection & Deployment Systems, Aerodynamic Interstage Systems, and Propulsion Systems. The company was founded on August 20, 2020 and is headquartered in Huntington Beach, CA.

Karman Holdings Inc.

Karman Holdings Ord Shs

KRMN is drawing attention amid a volatile bounce in defense and drone stocks, which traders describe as a rotation back into the sector; they also cite the companys missile-defense and space exposure, backlog, and contract prospects. Optimism about a recovery is countered by concerns over the prolonged decline and valuation, while some traders attribute the latest pullback to broad-market weakness.

Hims & Hers Health, Inc. operates a telehealth consultation platform. It connects consumers to healthcare professionals, enabling them to access medical care for mental health, sexual health, dermatology and primary care. The company was founded in 2017 and is headquartered in San Francisco, CA.

Hims & Hers Health Inc - Ordinary Shares - Class A

Hims & Hers Health Inc

HHSs temporary policy allowing compounding pharmacies to produce six peptides while regulators review them is driving attention, with traders viewing it as a potential new growth opportunity for Hims & Hers. Reactions are split: some expect the company to benefit from its peptide preparations, while others say the share-price response has been muted and want to see proof of commercial execution.

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iShares Trust - iShares TLT Premium Income+ ETF

Neutral Sentiment

Hold rates steady

Cut 25 bps

Hike 25 bps

Fed decision day is here - Kevin Warsh chairs his first FOMC meeting with markets pricing a hold at 3.50%-3.75% but watching for a hawkish shift. Vote on what you expect to be decided today, then drop your prediction for the first rate cut or hike in the comments.

What do you expect the Fed to decide at its FOMC meeting today? 
 
Drop a comment with when you expect the first cut/hike to be.

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iShares 20+ Year Treasury Bond BuyWrite Strategy ETF

$TLTW switch from monthly to weekly options has started.

Four option expirations 2% above yesterdays closing price of TLT …@$81.57

Note:  these are sold thru private placement and are European style options that can only be exercised on maturity date.

Martin killoran

$TLTW new series of options sold at close of business last Friday.
TLT closed at $81.34 ….option sold at strike price of $82.97….1.02% above closing price.
For Nov 20 at .56 cents

$TLTW  changes kick in tonight…..

BlackRock has announced a significant change to TLTW, your iShares 20+ Year Treasury Bond BuyWrite Strategy ETF. The fund is changing its name to iShares TLT Premium Income+ ETF and adopting a revised options strategy around October 15, 2026. The implementation date was postponed from the original September target.

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