SPDR Dow Jones Industrial Average ETF

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Netflix, Inc. engages in providing entertainment services. It also offers activities for leisure time, entertainment video, video gaming, and other sources of entertainment. It operates through the United States and International geographic segments. The company was founded by Marc Randolph and Wilmot Reed Hastings on August 29, 1997 and is headquartered in Los Gatos, CA.

Netflix Inc.

Netflix Inc

Netflix is generating considerable buzz around its potential acquisition of Warner Bros. Discovery, with speculation focusing on a revised all-cash offer amidst legal challenges from Paramount Skydance. This highly anticipated deal, alongside upcoming earnings, has polarized the community between those expecting a significant pre-earnings rally and others anticipating further volatility and potential downside, fueled by concerns over market manipulation and political opposition.

Warner Bros. Discovery, Inc. is a premier global media and entertainment company, which engages in the provision of a differentiated portfolio of content, brands, and franchises across television, film, streaming, and gaming. It operates through the following segments: Studios, Networks, Direct-to-Consumer (DTC), and Corporate. The Studios segment includes producing and releasing feature films for initial exhibition in theaters, producing and initial licensing television programs to networks services as well as third parties, distributing films and television programs to various third party, internal television, and streaming services, distribution through the home entertainment market related consumer products, and themed experience licensing and interactive gaming. The Networks segment focuses on domestic and international television networks. The DTC segment is involved in premium pay-television and streaming services. The company was founded on June 17, 1985 and is headquartered in New York, NY.

Warner Bros. Discovery Inc - Ordinary Shares - Class A

Warner Bros Discovery Inc

Warner Bros. Discovery (WBD) is trending as it navigates an escalating takeover battle, with its board reportedly favoring Netflix's acquisition proposal over Paramount Skydance's (PSKY) all-cash offer, despite a personal financing guarantee. The community is buzzing with debate, weighing PSKY's perceived superior value and the potential for a significantly higher bid from either contender to secure market dominance in the evolving media landscape. Shareholders are closely watching for definitive developments in this strategic consolidation.

UiPath, Inc. engages in the development and provision of a software platform to automate business processes. The firm serves the public, healthcare, telecommunication, finance, and banking industries. It also offers accounts payable automation, claims processing automation, contact center automation, and finance and accounting automation. The company was founded by Daniel Dines and Marius Tirca in 2005 and is headquartered in New York, NY.

UiPath Inc - Ordinary Shares - Class A

UiPath Inc

UiPath is trending due to a significant sell-off, with community discussion centering on ongoing CEO stock sales and potential competitive impacts from new AI agents like Anthropic's Claude Cowork. Despite this, many investors view the sharp dip as a strong buying opportunity, banking on the company's solid fundamentals, evolving leadership in agentic automation, and strategic partnerships to drive future growth.

Moderna, Inc. engages in the development of transformative medicines based on messenger ribonucleic acid. The firm's product pipeline includes the following modalities: prophylactic vaccines, cancer vaccines, intratumoral immuno-oncology, localized regenerative therapeutics, systemic secreted therapeutics, inhaled pulmonary therapeutics and systemic intracellular therapeutics. It operates through the following geographical segments: United States, Europe, and Rest of World. The company was founded by Noubar B. Afeyan, Robert S. Langer, Jr., Derrick J. Rossi, and Kenneth R. Chien in 2010 and is headquartered in Cambridge, MA.

Moderna Inc

Moderna is trending as the community reacts to positive developments concerning its pipeline, including global regulatory submissions for its seasonal flu vaccine and plans for a combined flu and COVID vaccine. Bulls are emphasizing the company's long-term potential in oncology and the possibility of a short squeeze, while others remain skeptical about its valuation and future revenue growth.

Candel Therapeutics, Inc. is a clinical stage biotechnology company, which engages in the development and commercialization of viral immunotherapies. Its pipeline includes CAN-2409 and CAN-3110. The company was founded by Estuardo Aguilar-Cordova in 2002 and is headquartered in Needham, MA.

Candel Therapeutics Inc

Candel Therapeutics (CADL) is trending amid intense community speculation regarding an imminent major partnership or acquisition, with Novartis frequently mentioned as a potential suitor. This excitement is amplified by the upcoming J.P. Morgan Healthcare Conference, a hub for anticipated biopharma M&A, and recent FDA flexibility on CMC requirements, which could accelerate the BLA submission for its lead prostate cancer drug, CAN-2409. The community is actively debating the company's current low valuation against its promising clinical data, eagerly anticipating a transformative deal or further clarity on its expedited regulatory path.

Adobe, Inc. is a global technology company, which engages in the provision of digital marketing and media solutions. It operates through the following segments: Digital Media, Digital Experience, and Publishing and Advertising. The Digital Media segment offers products and services that enable individuals, teams, businesses, and enterprises to create, publish, and promote content anywhere and accelerate productivity by transforming view, share, engage with and collaborate on documents and creative content. The Digital Experience segment focuses on integrated platform and set of products, services, and solutions that enable businesses to create, manage, execute, measure, monetize, and optimize customer experiences that span from analytics to commerce. The Publishing and Advertising segment includes legacy products and services that address diverse market opportunities, including eLearning solutions, technical document publishing, web conferencing, document and forms platform, web app development, high-end printing, and Adobe Advertising offerings. The company was founded by Charles M. Geschke and John E. Warnock in December 1982 and is headquartered in San Jose, CA.

Adobe Inc

Adobe is trending amid a wave of analyst downgrades and intensified debate around increasing AI-driven competition, notably from Apple's new creative software suite. While many investors see the stock as deeply undervalued given strong fundamentals and ongoing share buybacks, others express deep concern that AI advancements will erode Adobe's long-term market dominance. The community is sharply divided between those who believe the current dip is a prime buying opportunity and those who view it as a signal of structural weakness for the software giant.

🔥 COCK Token – The Ultimate Cross-Chain MemeFi Powerhouse 🔥  In just under 20 days, $COCK has smashed expectations, broken ATHs, and built a project that’s shaking up Cardano and the entire crypto space. 🐓 What Makes $COCK Special?      The Name: Love it or hate it, the energy and engagement it generates are undeniable. The nuance in language and wild appeal set us apart.     #MEMEFI Pioneer: We’re not just another meme coin. $COCK is leading a movement by combining DeFi mechanics, game theory, and community engagement into a groundbreaking ecosystem.     COCKARENA: At the core of our ecosystem is the COCKARENA, a PvP HODL game. Players battle it out, and early exit fees fuel redistributions, burns, and the treasury. This ensures price appreciation and long-term sustainability for loyal holders.  🎰 The COCK Casino  Our casino isn’t just fun—it’s a serious revenue stream for the FLOCK.      Games: Bonanza, Crash, Blackjack, and Roulette (coming soon!).     Impact: Over 7,834 ADA in profits generated within days, directly supporting rewards, burns, and reinvestment.  💰 COCK-ARENA Loans  Unlock liquidity without selling your tokens.      Loan Terms: Borrow up to 30% of your holdings while continuing to earn rewards in the arena.     Investor Focus: Perfect for savvy investors staying in the game while tapping into their holdings.  🤝 Our Insane Partnerships  We’re bridging gaps, building alliances, and breaking barriers across the crypto space. Key Partners:      DANZO: Powering #MEMEFI with Arena, Casino, and Loans.     KLENEK: Interactive training room.     HSKN (Charles Hoskilien): Supporting and starting COCKPIN with 115 AIR NODES for DePIN aggregation. Plans to add APEX and Earth Nodes through a crypto company incorporated in Costa Rica.     ELITE CATS / SNEKKIES / HOT / BANK: Rewarding NFT holders with COCK-LOCK tokens and vice versa.     OCKZ: COCKSOCKS, Golden Cock Ticket (1M COCK), airdrop rewards, and whitelist perks for holders of 200 ADA worth of $COCK.     OLI Partnership:         Content Creation: Lux and the team are crafting engaging educational content about memes and MemeFi for OLi's platform.         Strategic Investment: The OLi Community Trust will invest in $COCK, distributing 100% of rewards to $OLI holders.         Community Reach: Over 22,000 learners will discover $COCK through OLi's gamified ecosystem.     Hi-Rez the Rapper: Expanding reach in marketing and entertainment.     KUNO, CALEB, CADEN, FITY, ROVER, WhaleInsider: Influential collaborators driving crypto adoption and growth.     Cardano Girls: Helping us understand and communicate effectively with ADA’s female audience.     WallStreetBets: Breaking barriers and increasing engagement.     Antonio Brown: Endorsing, supporting, and even playing in the casino and arena!     Advisors:         BERIS, HECKTHESNEK, RTB, CRYPTOGENIUS: Trusted names advising and supporting the project.  Future Partnerships:  More collaborations are in the pipeline to continue expanding engagement and bring new eyes to ADA and CNTs. 🔥 Unmatched Results in Just 20 Days      Supply Burned: 1.65%, worth 148K ADA!     Arena Fees Collected: 54M COCK, worth over 500K ADA, fueling rewards, burns, and partnerships.     Staked COCK-LOCK: 11M COCK-LOCK in the liquid staking platform, with more coming.     Casino Revenue: Skyrocketing profits directly rewarding holders and growing the treasury.     Top Blast Contests: Generated over 120K ADA in volume, rewarding participants with over 50K ADA in prizes.  🌍 Our Vision  To be the most decentralized, rewarding, and innovative token on Cardano while fostering cross-chain collaboration and onboarding the masses.      Breaking Barriers: We’re bringing BTC, ETH, SOL, and other chains into the fold.     Community-Driven: Focused on building bridges and showcasing that crypto can be fun, rewarding, and sustainable.     Expansion: This is just the beginning. With more burns, rewards, and partnerships on the way, $COCK is set to redefine what’s possible in the MemeFi space.  💎 Time in the arena &gt; Timing the market. The FLOCK is unstoppable. Let’s keep breaking walls for Cardano and onboard new users as we take $COCK to new heights.

CockCardano

CockCardano ($COCK) is a vibrant Cardano-based meme coin trending due to its unique real-world asset (RWA) venture, CockyWings, which sells chicken wings. The enthusiastic 'Flock' community is actively engaged, highlighting the project's innovative staking features, consistent building, and strong potential within the broader Cardano ecosystem.

Paramount Skydance Corp. is a next-generation global media and entertainment company that engages in providing content creation and distribution services. It operates through the following business segments: Studios, Direct-to-Consumer, and TV Media. Its portfolio unites brands including Paramount Pictures, Paramount Television, CBS, CBS News, Nickelodeon, MTV, BET, Comedy Central, Showtime, Paramount Plus, Pluto TV, and Skydance’s Animation, Film, Television, Interactive/Games, and Sports divisions. The company was founded on June 3, 2024 and is headquartered in New York, NY.

Paramount Skydance Corp. - Ordinary Shares - Class B

Paramount Skydance is at the center of a contentious takeover bid for Warner Bros. Discovery, persistently pushing its all-cash offer while challenging Netflix's rival deal. The community is intensely debating WBD's repeated rejections, with many questioning if the board is prioritizing personal interests over shareholder value, especially as PSKY escalates with a lawsuit seeking financial transparency and plans to nominate new directors. This ongoing media M&A drama is further complicated by anticipated regulatory scrutiny for the alternative Netflix bid.

Intel Corp. engages in the design, manufacture, and sale of computer products and technologies. It delivers computer, networking, data storage, and communications platforms. The firm operates through the following segments: Client Computing Group (CCG), Data Center and AI (DCAI), Network and Edge (NEX), Mobileye, Accelerated Computing Systems and Graphics (AXG), Intel Foundry Services (IFS), and All Other. The CCG segment consists of platforms designed for notebooks, 2-in-1 systems, desktops, tablets, phones, wireless and wired connectivity products, and mobile communication components. The DCAI segment delivers solutions to cloud service providers and enterprise customers, along with silicon devices for communications service providers and high-performance computing customers. The NEX segment offers computing system solutions from inflexible fixed-function hardware to general-purpose compute, acceleration, and networking devices running cloud native software on programmable hardware. The Mobileye segment develops driving assistance and self-driving solutions. The AXG segment provides products and technologies designed to help customers solve the toughest computational problems. Its products include CPUs for high-performance computing and GPUs targeted for a range of workloads and platforms, from gaming and content creation on client devices to delivering media and gaming in the cloud, and the most demanding high-performance computing and AI workloads on supercomputers. The IFS segment refers to full stack solutions created from the foundry industry ecosystem. The All Other segment represents results from other non-reportable segments and corporate-related charges. The company was founded by Robert Norton Noyce and Gordon Earle Moore on July 18, 1968 and is headquartered in Santa Clara, CA.

Intel Corp.

Intel Corp

Intel is trending significantly higher following a major analyst upgrade that cited robust hyperscaler demand for its server CPUs, leading to a near sell-out of 2026 supply and potential price increases. The community is actively debating strong bullish momentum and short squeeze potential, while skeptics warn of unsustainable hype given historical performance.

SSgA Active Trust - SPDR Dow Jones Industrial Average ETF

DIA is highly active as a criminal investigation into Fed Chair Powell sparks significant debate about central bank independence and potential market volatility. This catalyst combines with Trump administration actions on tariffs and Venezuela, leading the community to intensely discuss geopolitical risks, the likelihood of a market sell-off, and whether defensive rotations will hold.

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Microsoft Corporation

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<ul class="summary-bullets"><li>The timeline extension comes on the heels of the FDA requesting additional information to assess Filspari’s clinical benefit.</li><li>The company submitted responses and the agency determined that the responses constitute a major amendment to the application.&nbsp;</li><li>The FDA is now expected to decide on the application by April 13, 2026.</li></ul>Shares of Travere Therapeutics, Inc., (TVTX) traded 19% lower on Tuesday after the company announced that U.S. Food and Drug Administration (FDA) has extended the review timeline for its application seeking approval of Filspari in focal segmental glomerulosclerosis.The FDA is now <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://ir.travere.com/press-releases/news-details/2026/Travere-Therapeutics-Announces-FDA-Extends-Review-of-sNDA-for-FILSPARI-sparsentan-in-FSGS/default.aspx">expected</a> to decide on the application by April 13, 2026. The agency was initially expected to rule on the application by Jan. 13.<h2 class="st-heading-2">Why The Delay?</h2>The timeline extension comes on the heels of the FDA requesting additional information to assess Filspari’s clinical benefit. The company submitted responses, and the agency determined that the responses constitute a major amendment to the application, and extended the review timeline, the company said. The agency requested no additional information on the safety or manufacturing of Filspari, it added.According to Travere, Filspari would be the first medication indicated for focal segmental glomerulosclerosis if approved. FSGS is a kidney disease causing sclerosis, or scarring in some filters of the kidneys, leading to protein leakage, swelling, and potentially kidney failure.CEO Eric Dube said that the company remains committed to working with the FDA during the extension period and making preparations for a potential commercial launch.Filspari is also approved by the FDA to slow kidney function decline in adults with IgA nephropathy, a chronic autoimmune kidney disease where deposits of the immunoglobulin A (IgA) antibody build up in the kidney's filters, causing inflammation, scarring, and damage.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>On Stocktwits, retail sentiment around TVTX stock jumped from ‘bullish’ to ‘extremely bullish’ territory over the past 24 hours, while message volume rose from ‘high’ to ‘extremely high’ levels.A Stocktwits user opined that the FDA would eventually reject the drug.<stembedurl>https://www.stocktwits.com/Steve_TheBull_Rogers/message/641686497</stembedurl>Another opined that the FDA wouldn’t have extended the review timeline if it was planning on a rejection.<stembedurl>https://www.stocktwits.com/apux/message/641686139</stembedurl><a href="https://stocktwits.com/symbol/TVTX">TVTX stock</a> has gained 48% over the past 12 months.&nbsp;Read More: <a href="https://stocktwits.com/news-articles/markets/equity/fund-manager-flags-concerns-about-tesla-dwindling-delivery-numbers-high-pe-ratio/cmUXXNkR4Ia">Fund Manager Flags Concerns About Tesla’s Dwindling Delivery Numbers, Notes High P/E Ratio</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, the Travere Therapeutics logo is seen displayed on a smartphone screen. (Photo Illustration by Thomas Fuller/SOPA Images/LightRocket via Getty Images)

Travere Therapeutics Stock Slumps After FDA Extends Drug Review Timeline To April: Retail Is Divided On Eventual Approval

According to Travere, Filspari would be the first medication indicated for focal segmental glomerulosclerosis if approved. 

Equity

According to Travere, Filspari would be the first medication indicated for focal segmental glomerulosclerosis if approved. 


<ul class="summary-bullets"><li>Company CEO Doug Ingram said that the company “faced and overcame challenges in 2025.”</li><li>Elevidys, a medicine intended for the treatment of Duchenne muscular dystrophy (DMD), created safety concerns following the death of two patients after treatment.</li><li>Analysts on average expect the company to report total revenue of $2.12 billion for full year 2025.</li></ul> Shares of Sarepta Therapeutics Inc. (SRPT) sank 12% on Monday after the company said that it expects full year 2025 net product revenue of $1.86 billion, marking only slight growth from the $1.79 billion reported for full year 2024.Net product revenue refers to the company’s revenue from its products and does not include collaboration, contract manufacturing or royalty revenue.Analysts on average expect the company to report total revenue of $2.12 billion for full year 2025, according to data from Fiscal AI.<h2 class="st-heading-2">Results Breakdown</h2>Sarepta <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://investorrelations.sarepta.com/news-releases/news-release-details/sarepta-reports-preliminary-fourth-quarter-and-full-year-2025">now sees</a> revenue from its top-selling gene therapy Elevidys for the full year to come to $898.7 million, including fourth quarter revenue of $110.4 million. The company said that the therapy’s revenue in the three months through the end of December was impacted by the year-end flu season and the need to reschedule six patient infusions into 2026.Revenue from the company’s other therapies for the full year is now expected at $965.6 million.Company CEO Doug Ingram said that the company “faced and overcame challenges in 2025.” “We have important initiatives in 2026 to continue the success of our approved therapies, particularly ELEVIDYS. We previously set a yearly sales floor for ELEVIDYS of $500.0 million. We reconfirm that floor and our intentions to exceed it,” Ingram said on Monday.The company further added that it had $953.8 million in preliminary cash, cash equivalents, restricted cash and investments as of 2025-end. The company will announce its full financial results in late February.<h2 class="st-heading-2">Elevidys Safety Concerns And Other Setbacks</h2>The preliminary numbers come in light of a challenging year for the company. Elevidys, a medicine intended for the treatment of Duchenne muscular dystrophy (DMD), created safety concerns following the death of two patients after treatment. Both non-ambulatory patients suffered from acute liver failure. DMD is a severe, inherited genetic disorder that causes progressive muscle weakness and degeneration.While Sarepta resumed shipments to DMD patients who can walk after a temporary pause, it is now developing a risk-mitigation approach for patients who cannot walk to resume shipments in the particular patient segment.In November, the company also announced that its two approved therapies Amondys 45 and Vyondys 53 in DMD failed in a key confirmatory trial aimed at a traditional full approval for the two. The company, however, continues to eye traditional approval based on the positive risk-benefits of the therapies and real-world evidence.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>On Stocktwits, retail sentiment around SRPT rose from ‘bullish’ to ‘extremely bullish’ territory over the past 24 hours while message volume increased from 'high’ to 'extremely high' levels.A Stocktwits user dismissed the sell-off and opined that the “Elevidys story isn’t broken.” They also noted that the company has enough cash to cover liabilities.<stembedurl>https://www.stocktwits.com/Initiator1/message/641562456</stembedurl>Another dismissed the selloff as a "minor setback."<stembedurl>https://www.stocktwits.com/ZzyzxResearch/message/641561010</stembedurl><a href="https://stocktwits.com/symbol/SRPT">SRPT stock</a> is down 82% over the past 12 months.Read More: <a href="https://stocktwits.com/news-articles/markets/equity/why-did-lvlu-stock-surge-today/cmUaI8XR4Eo">Why Did LVLU Stock More Than Double Today?</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, the Sarepta Therapeutics logo is seen displayed on a smartphone screen. (Photo Illustration by Thomas Fuller/SOPA Images/LightRocket via Getty Images)

SRPT Stock Tumbles 12% On Lackluster Preliminary Revenue Numbers Due To Elevidys Safety Concerns

Sarepta now sees revenue from its top-selling gene therapy Elevidys for the full year to come to $898.7 million.

<ul class="summary-bullets"><li>The company last year in a social media post said that its BlueBird 7 will ship to the Cape Canaveral launch site in October.</li><li>AST said it remains on track to complete 40 phased arrays by early 2026.</li><li>One bullish user predicted the stock price to touch $113 if the current rally breaks the $102 mark.</li></ul>AST SpaceMobile (ASTS) shares soared more than 10% on Friday and were among top trending stocks on Stocktwits as retail investment was buoyed by a recent upgrade from Bank of America.&nbsp;Investors were actively discussing the stock's potential breakout, and the firm's development announcement regarding its BlueBird’s launch in December and the expected fleet to be <a href="https://stocktwits.com/18KGold/message/641353923">launched</a> in 2026, as well as the company's long-term <a href="https://stocktwits.com/StockAnalyst_SA/message/641359044">potential</a> in space communications.&nbsp;Bank of America raised the firm's price target on AST SpaceMobile to $100 from $85 and keeps a ‘Neutral’ rating.BofA in a note said that it is ‘neutral’ on data centers, ‘bullish’ on towers, and projects growing interest in Low-Earth-Orbit (LEO) satellite providers in 2026, as per TheFly.&nbsp;Earlier, Scotiabank had downgraded AST SpaceMobile to ‘Underperform’ from ‘Sector Perform’ with a $45.60 price target.&nbsp;<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>Retail sentiment around ASTS trended in ‘extremely bullish’ territory amid ‘high’ message volumes.&nbsp;One user predicted that Elon Musk may try to buy the firm from the proceeds of SpaceX IPO.&nbsp;<stembedurl>https://stocktwits.com/Longdriver/message/641351687</stembedurl>Another user predicted the stock price to touch $113 if the current rally breaks the $102 mark.&nbsp;<stembedurl>https://stocktwits.com/A1stocks42/message/641349592</stembedurl><h2 class="st-heading-2">Starlink Challenger</h2>BlueBird 6 is AST SpaceMobile’s first next-generation satellite that aims to provide 4G/5G to standard phones and potentially challenge Elon Musk’s Starlink.It was launched last month from India’s Satish Dhawan Space Centre in Sriharikota. The company has said that it is the largest commercial communications array ever deployed in Low-Earth-Orbit.&nbsp;The company last year said in a social media <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://x.com/AST_SpaceMobile/status/1973140310478688452">post</a> that its BlueBird 7 will ship to the Cape Canaveral launch site in October. It added that BlueBirds 8-16 are in various stages of production, with launches planned every 1-2 months on average during 2025 and 2026.&nbsp; AST said it remains on track to complete 40 phased arrays by early 2026. It expects 45-60 satellites in orbit by year-end 2026.&nbsp;Shares of AST SpaceMobile have surged nearly 120% in the past six months.&nbsp;For updates and corrections, email newsroom[at]stocktwits[dot]com. &nbsp;

In this photo illustration, the AST SpaceMobile (Space Mobile) logo is seen displayed on a smartphone screen. (Photo Illustration by Thomas Fuller/SOPA Images/LightRocket via Getty Images)

AST SpaceMobile Has Rallied 120% In Past 6 Months, Retail Still Seeing Upside Potential

Bank of America raised the firm's price target on AST SpaceMobile to $100 from $85 and keeps a ‘Neutral’ rating.

<ul class="summary-bullets"><li>Imcivree is Rhythm’s only approved drug and the company is now looking forward to an FDA approval for the drug in the treatment of acquired hypothalamic obesity.</li><li>The FDA is expected to rule on the company’s application by March 20, 2026.</li><li>The company is also exploring the drug’s potential in treating other rare diseases including congenital hypothalamic obesity and Prader-Willi Syndrome.</li></ul>Shares of Rhythm Pharmaceuticals, Inc. (RYTM) jumped 4% on Friday after the company reported preliminary full-year Imcivree revenue of approximately $194 million, marking a growth of about 50% from FY24.Fourth quarter Imcivree revenue is expected to be about $57 million, marking a quarter-on-quarter growth of 11%. Imcivree is Rhythm’s only approved drug and the company is now looking forward to an approval from the U.S. Food and Drug Administration (FDA) for the drug in the treatment of <a href="https://stocktwits.com/news-articles/markets/equity/rhythm-pharma-experimental-drug-yields-weight-reduction-in-brain-damage-related-obesity/chFy2A1R5KT">acquired hypothalamic obesity.</a>The FDA is expected to rule on the company’s application by March 20, 2026.<h2 class="st-heading-2">Imcivree’s Current Use</h2>Imcivree is currently approved by the FDA to reduce excess body weight and maintain weight reduction long term in adult and pediatric patients two years and older with syndromic or monogenic obesity due to Bardet-Biedl syndrome. Bardet-Biedl syndrome is a rare genetic disorder affecting multiple body systems, characterized by vision loss, obesity, kidney problems, genital abnormalities, and learning disabilities.About 70% of the drug’s revenue for the year and the fourth quarter came from U.S. sales, Rhythm said. The company is also exploring the drug’s potential in treating other rare diseases including congenital hypothalamic obesity and <a href="https://stocktwits.com/news-articles/markets/equity/rhythm-pharmaceuticals-stock-rises-after-positive-study-data-for-setmelanotide-in-treating-genetic-disorder/cLIxj7cREFG">Prader-Willi Syndrome</a> in addition to advancing its other experimental drugs Bivamelagon and RM-718 in acquired hypothalamic obesity.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>On Stocktwits, retail sentiment around RYTM stock stayed within the ‘bearish’ territory over the past 24 hours, while message volume stayed at ‘low’ levels.A Stocktwits user opined that the preliminary revenue numbers put speculation of slowing revenue growth to rest.<stembedurl>https://www.stocktwits.com/Stonky_Mcprofitface/message/641320511</stembedurl><a href="https://stocktwits.com/symbol/RYTM">RYTM stock</a> has gained 80% over the past 12 months.&nbsp;Read More: <a href="https://stocktwits.com/news-articles/markets/equity/general-motors-incurs-7.1-billion-in-charges-in-q4/cmUbl4LR451">General Motors Incurs $7.1B In Charges In Q4 Pertaining To Slowing EV Demand, China Business Restructuring</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, the Rhythm Pharmaceuticals company logo is seen displayed on a smartphone screen. (Photo Illustration by Piotr Swat/SOPA Images/LightRocket via Getty Images)

RYTM Stock Jumps 4% On Imcivree Revenue Growth: Firm Awaits Approval In Acquired Hypothalamic Obesity By March

Fourth quarter Imcivree revenue is expected to be about $57 million, marking a quarter-on-quarter growth of 11%.

<ul class="summary-bullets"><li>KalVista launched Ekterly in the U.S. in July for the treatment of acute attacks of hereditary angioedema in adults and children aged 12 years and older.</li><li>Through the full year 2025, the company recorded global Ekterly revenue of $49 million.</li><li>Kalvista now plans to file a new drug application with the FDA for the drug in pediatric HAE patients aged 2 to 11 years in the third quarter of 2026.</li></ul>Shares of KalVista Pharmaceuticals, Inc. (KALV) jumped 14% after hours on Thursday after the company said that it recorded about $35 million in revenue from its one and only approved drug Ekterly in the fourth quarter, merely months after launch.KalVista <a href="https://stocktwits.com/news-articles/markets/equity/kalvista-gets-fda-approval-for-drug-in-treating-swelling-disorder/chFtmFCR57B">launched</a> Ekterly in the U.S. in July for the treatment of acute attacks of hereditary angioedema in adults and children aged 12 years and older. The company said that in the three months through the end of December, prescription refills surpassed initial prescriptions as the primary driver of revenue.Hereditary angioedema (HAE) is a rare genetic disease caused by deficiency or dysfunction of a protein called the C1 esterase inhibitor, where patients experience painful and debilitating attacks of tissue swelling in various locations of the body that can be life-threatening depending on the area affected.<h2 class="st-heading-2">Ekterly’s Edge</h2>Ekterly is the first and only oral on-demand treatment for HAE, KalVista said, setting it apart from other on-demand HAE treatment options approved in the U.S., which require intravenous or subcutaneous administration.Through the full year 2025, the company recorded global Ekterly revenue of $49 million. The drug is now approved in seven global markets including the U.S., United Kingdom, European Union, Switzerland, Australia, Singapore and Japan.“Fundamental demand has remained strong, with some effects from seasonal variability, and we are encouraged by the continued high level of interest in switching to EKTERLY,” CEO Ben Palleiko said. “Internationally, we are seeing strong uptake in Germany, with early prescribing behaviors mirroring the positive trends we observed in the US, and we expect to expand into other major markets during 2026.”Kalvista now plans to file a new drug application with the FDA for the drug in pediatric HAE patients aged 2 to 11 years in the third quarter of 2026. The company envisions launching the drug for the younger population in the U.S. in 2027.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>On Stocktwits, retail sentiment around KalVista jumped from ‘bullish’ to ‘extremely bullish’ territory over the past 24 hours, while message volume stayed at ‘high’ levels.A Stocktwits user applauded the numbers as an “incredible start to Ekterly sales.” “This has a squeeze written all over it,” the user added.<stembedurl>https://www.stocktwits.com/pblegend66/message/641279255</stembedurl>Another user highlighted the drug’s potential and noted that the company could make as much as $340 million in revenue from the drug.<stembedurl>https://www.stocktwits.com/Biocontrol/message/641276040</stembedurl><a href="https://stocktwits.com/symbol/KALV">KALV stock</a> has gained 92% over the past 12 months.Read More: <a href="https://stocktwits.com/news-articles/markets/equity/general-motors-incurs-7.1-billion-in-charges-in-q4/cmUbl4LR451">General Motors Incurs $7.1B In Charges In Q4 Pertaining To Slowing EV Demand, China Business Restructuring</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

Rising stock market chart on a trading board background.

KalVista Pharmaceuticals Stock Rallies After Hours On Strong Genetic Disorder Drug Sales Kickstart

Ekterly is the first and only oral on-demand treatment for HAE, KalVista said, setting it apart from other on-demand HAE treatment options approved in the U.S.

<ul class="summary-bullets"><li>MannKind is now eyeing a potential approval of its Afrezza inhalation powder for children and adolescents living with type 1 or type 2 diabetes.</li><li>H.C. Wainwright reiterated a ‘Buy’ rating on MannKind with an $11 price target after the company’s update.</li><li>The firm said it is positive on MannKind's outlook over the next two years, saying "very little value is ascribed to the multiple tailwinds that could be validated in 2026."</li></ul>MannKind Corporation (MNKD) on Thursday said that it expects two high potential launches going into 2026, driving investor optimism and sending shares up 2%.&nbsp; “With two high-potential launches on the horizon, 2026 is shaping up to be a catalyst-rich year that positions MannKind for long-term value creation,” CEO Michael Castagna<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/news-release/2026/01/08/3215359/29517/en/MannKind-Provides-Business-Updates-and-2026-Growth-Drivers.html"> said,</a> while adding that the company closed 2025 “on a high note” with its acquisition of scPharmaceuticals.<h2 class="st-heading-2">MannKind’s Potential Launches</h2>MannKind is now eyeing a potential approval of its Afrezza inhalation powder for children and adolescents living with type 1 or type 2 diabetes. The U.S. Food and Drug Administration is expected to rule on the application by May 29 and if approved, it would be the first needle-free insulin option for pediatric patients in over 100 years of insulin therapy, the company said.The company is also eyeing approval for its FUROSCIX ReadyFlow Autoinjector, developed to deliver a subcutaneous furosemide injection in under 10 seconds as an investigational alternative to the FDA-approved FUROSCIX On-body Infusor. Furosemide is used for treatment of edema in adult patients with chronic heart failure (CHF) or chronic kidney disease (CKD).<h2 class="st-heading-2">Analyst Weighs In</h2>H.C. Wainwright reiterated a ‘Buy’ rating on MannKind with an $11 price target after the company’s update. The price target represents a potential upside of about 88% from the stock's closing price on Wednesday.&nbsp;The firm said it is positive on MannKind's outlook over the next two years, saying "very little value is ascribed to the multiple tailwinds that could be validated in 2026."<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>On Stocktwits, retail sentiment around MNKD shares jumped from ‘neutral’ to ‘bullish’ territory over the past 24 hours while message volume rose from ‘normal’ to ‘high’ levels.A Stocktwits user dismissed the company’s Thursday update as “another pump and dump.”<stembedurl>https://www.stocktwits.com/Kool_Aid_Mann/message/641251643</stembedurl><a href="https://stocktwits.com/symbol/MNKD">MNKD stock</a> has dropped 3% over the past 12 months.&nbsp;Read More: <a href="https://stocktwits.com/news-articles/markets/equity/ford-stock-rallies-on-piper-sandler-upgrade-plans-to-launch-autonomous-driving-on-30000-ev/cmUbiTNR45X">Ford Stock Rallies On Piper Sandler Upgrade, Plans To Launch Autonomous Driving On $30,000 EV</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

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MannKind Rallies On Optimism Of Two Imminent Product Launches: Analyst Sees ‘Multiple Headwinds’ For Stock In 2026

The company’s CEO Michael Castagna said that with two high-potential launches on the horizon, 2026 is shaping up to be a catalyst-rich year that positions MannKind for long-term value creation. 

<ul class="summary-bullets"><li>Archer plans to showcase the technology at its recently acquired Hawthorne Municipal Airport facility in Los Angeles.</li><li>IGX Thor is an advanced safety-capable AI computing module.</li><li>Archer said the AI platform will also have applications across manufacturing, fleet operations, and pilot training.</li></ul>Archer Aviation (ACHR) shares rose 5% on Thursday after the company unveiled a major artificial intelligence initiative at the Consumer Electronics Show (CES) 2026, deepening its partnership with NVIDIA to develop next-generation aviation technologies.Archer will integrate NVIDIA’s IGX Thor platform into future versions of its Midnight electric air taxi. IGX Thor is an advanced safety-capable AI computing module, designed for real-time performance.Archer plans to showcase the technology at its recently acquired Hawthorne Municipal Airport facility in Los Angeles, which is expected to serve as the operational hub for its planned LA air taxi network. Archer will also deploy the airport as a testing ground for next-generation aviation technologies.<h2 class="st-heading-2">Partnership Details</h2>The partnership will focus on three areas: enhancing pilot safety through real-time environmental sensing and predictive awareness, enabling smoother integration into complex airspace with AI-driven traffic and routing systems, and building autonomy-ready flight controls that can support future semi-autonomous and autonomous operations. Archer said the AI platform will also have applications across manufacturing, fleet operations, and pilot training.The announcement comes as Archer remains in the spotlight following recent efforts to partner with U.S. cities under the federal eVTOL Integration Pilot Program (eIPP), which aims to support the rollout of air taxis this year. Its applications include public-private partnerships across California, Texas, Florida, Georgia, and New York.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>Retail sentiment on Stocktwits turned ‘extremely bullish’ from ‘bullish’ a day earlier, amid ‘high’ message volumes. <a href="https://stocktwits.com/symbol/ACHR">ACHR</a> was among the top trending tickers on the platform at the time of writing. &nbsp;<img src="https://news.stocktwits-cdn.com/archr_jpg_294883a2ff.webp" alt="archr.jpg">One user stated that the stock should break and hold above the $9 resistance for further rally.<stembedurl>https://stocktwits.com/fuegie/message/641222039</stembedurl>Over the past year, ACHR shares have declined more than 17%.Read Also: <a href="https://stocktwits.com/news-articles/markets/equity/why-did-elvn-stock-shoot-up-60-percent-today/cmUbQNvR45E">ELVN Stock Shot Up 60% Today – What’s Driving The Rally?</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

The Midnight electric vertical takeoff and landing (EVTOL) aircraft from the American company Archer Aviation at the 54th International Paris Air Show (SIAE) on June 23, 2023 at Le Bourget. (Photo by Thierry NECTOUX/Gamma-Rapho)

ACHR Stock Gained 5% Today – Why Investors Are Enthusiastic About Its Partnership With NVIDIA? 

Archer will integrate NVIDIA’s IGX Thor platform into future versions of its Midnight electric air taxi.

<ul class="summary-bullets"><li>As of Dec. 22, 2025, 60 heavily pretreated patients were enrolled, and ELVN-001 delivered strong efficacy by 24 weeks.</li><li>Enliven plans to present additional Phase 1 data in mid-2026.</li><li>The company plans to initiate the Phase 3 ENABLE-2 trial in the second half of 2026.</li></ul>Enliven Therapeutics (ELVN) stock surged as high as 60% on Thursday after the company reported positive initial data from its ongoing Phase 1b ENABLE clinical trial evaluating ELVN-001 in patients with chronic myeloid leukemia (CML).<a href="https://stocktwits.com/symbol/ELVN">ELVN shares</a> jumped to their highest levels in more than a year on Thursday before paring some of those gains.ELVN-001 is a highly selective small-molecule inhibitor designed to directly target the BCR::ABL gene fusion, the key disease driver in CML. As of Dec. 22, 2025, 60 heavily pretreated patients had been enrolled in the study, with more than half having received four or more prior tyrosine kinase inhibitors (TKIs), including Asciminib and Ponatinib medications. ELVN-001 showed strong efficacy by 24 weeks.In the initial 80 mg once-daily cohort, 38% of patients achieved a major molecular response (MMR), while 16% reached a deep molecular response (DMR). In the randomized 60 mg and 120 mg cohorts, MMR and DMR rates rose to 53% and 35%, respectively. All patients who entered the study already in MMR maintained or improved their responses.The drug demonstrated consistent activity across doses from 60 mg to 120 mg, with no clear dose-response differences observed. Importantly, ELVN-001 was well tolerated, with no maximum tolerated dose identified and no new safety concerns reported.<h2 class="st-heading-2">2026 Pipeline</h2>Enliven plans to present additional Phase 1 data in mid-2026, align with the FDA on dose selection and Phase 3 design, and initiate the Phase 3 ENABLE-2 trial in the second half of 2026.“Momentum has been building over the last year leading to significant interest in our Phase 3 clinical trial from sites all around the world. We are preparing for upcoming regulatory interactions with the FDA to align on dose selection and support initiation of the Phase 3 trial in the second half of 2026,” said Helen Collins, M.D., Chief Medical Officer of Enliven.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>Retail sentiment on Stocktwits turned ‘extremely bullish’ from ‘bullish’ a day earlier, amid ‘extremely high’ message volumes.<img src="https://news.stocktwits-cdn.com/ELVN_jpg_83e5ce76dc.webp" alt="ELVN.jpg">One user sees $30 as a key resistance point.<stembedurl>https://stocktwits.com/Aburose/message/641205036</stembedurl>The stock has fallen around 1.5% over the past year.Read also: <a href="https://stocktwits.com/news-articles/markets/equity/why-did-crmd-stock-crash-28-today/cmUbayOR45b">Why Did CRMD Stock Crash 28% Today?</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

ELVN Stock Shot Up 60% Today – What’s Driving The Rally?

The company reported positive initial data from its ongoing Phase 1b clinical trial evaluating ELVN-001 in patients with chronic myeloid leukemia.

<ul class="summary-bullets"><li>The company posted revenue of $126.6 million beating analyst estimates of $81.2 million, according to data from Fiscal.ai.</li><li>Applied Digital has signed leases with two hyperscalers across two campuses in North Dakota with CoreWeave and a U.S. based investment-grade hyperscaler.</li><li>Its adjusted earnings per share came in at breakeven ($0.00). Analysts had expected a loss of $0.12 per share.</li></ul>Applied Digital on Wednesday reported that its second quarter (Q2) revenue more than tripled helped by robust growth in its high-performance computing business.&nbsp;The company posted revenue of $126.6 million, a 250% jump from the prior year comparable period. It also beat analyst estimates of $81.2 million, according to data from Fiscal.ai.“The Dakotas represent a compelling region for hyperscalers due to their cool climate and abundant energy. We believe our first-mover advantage, combined with our proven ability to execute technically complex data center construction, positions Applied Digital with a strong competitive advantage,” said Wes Cummins, Chairman and Chief Executive Officer. &nbsp;&nbsp;The company’s adjusted earnings per share came in at breakeven ($0.00). Analysts had expected a loss of $0.12 per share.&nbsp;Shares in Applied Digital were up nearly 1% in after-market hours of trading.&nbsp;<h2 class="st-heading-2">Strong High-Performance Computing Business</h2>Applied Digital’s HPC hosting business contributed $85 million to the company’s revenue. Its data center hosting contributed $41.6 million, up 15% year-over-year.&nbsp;Applied Digital’s High-Performance Computing (HPC) Hosting Business designs, builds, and operates next-generation data centers, providing massive computing power to support HPC applications in a cost-effective model.It said operations have commenced at its first HPC data center at Polaris Forge 1 with 100 MW of capacity. A second 150 MW HPC data center is under construction at the same campus and is expected to come online in calendar 2026, while a third 150 MW facility is anticipated in calendar 2027.<h2 class="st-heading-2">Lease Agreements</h2>Applied Digital has signed leases with two hyperscalers across two campuses in North Dakota with CoreWeave and a U.S. based investment-grade hyperscaler. These lease agreements bring total leased capacity to 600 MW and aggregate prospective lease revenue to approximately $16 billion before exercise of any renewal options.CoreWeave paid about $85.0 million this quarter, including $73.0 million for tenant fit-out activities and Applied Digital recognized $12.0 million in partial-quarter lease revenue, it said in a statement.&nbsp;<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>Retail sentiment around APLD trended in ‘extremely bullish’ territory amid ‘extremely high’ message volume.&nbsp;Shares in Applied Digital have rallied nearly 200% over the past year.&nbsp;For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, a smartphone displays the logo of Applied Digital Corporation (NASDAQ: APLD) on July 28, 2025, in Chongqing, China. 

Applied Digital Posts 250% Jump In Its Quarterly Revenue

Applied Digital’s HPC hosting business contributed $85 million. Its data center hosting contributed $41.6 million, up 15% year-over-year. 

<ul class="summary-bullets"><li>Joby first announced its plans to double production in 2027 in December.</li><li>Company CEO JoeBen Bevirt also noted that the new facility can serve as a base for significant future growth.</li><li>The investment comes amid easing in the U.S. regulatory environment pertaining to eVTOLS.</li></ul> Shares of Joby Aviation, Inc. (JOBY) declined over 1% on Wednesday after the eVTOL maker said that it has inked a deal to acquire a manufacturing facility in Dayton, Ohio, for $61.5 million.The new facility spans more than 700,000 feet and is ready for immediate use, the California-based company <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://ir.jobyaviation.com/news-events/press-releases/detail/169/joby-to-expand-manufacturing-footprint-with-acquisition-of">said</a>. The deal is part of Joby’s ambitions to double production to four aircrafts per month in 2027.Operations at the new facility, purchased from Capstone STS LLC, are expected to begin this year. Joby already has facilities in California and Ohio and the new facility can serve as a base for “significant future growth,” CEO JoeBen Bevirt noted.<h2 class="st-heading-2">Joby Eyes Manufacturing At Scale</h2>Last year, Joby, which has received millions from Japanese automaker Toyota to support production, completed an expanded manufacturing facility in Marina and started propeller blade production in Ohio. Joby first announced its plans to double production in 2027 in December. The company also said at the time that it has begun procurement of the capital equipment required to double manufacturing capacity.Joby’s investment to expand manufacturing capacity came on the heels of U.S. Secretary of Transportation Sean Duffy unveiling a strategy aimed at improving support for the deployment and integration of electric air taxis. In September, Duffy also announced a new pilot program to allow some aircraft designs to demonstrate eVTOL use cases, such as passenger transportation, cargo delivery, and emergency response, ahead of achieving type certification. The Federal Aviation Administration is expected to deploy the pilot program in 2026.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>On Stocktwits, retail sentiment around JOBY stock stayed within the ‘extremely bullish’ territory over the past 24 hours, while message volume stayed at ‘high’ levels.<a href="https://stocktwits.com/symbol/JOBY">JOBY stock</a> has gained 57% over the past 12 months.&nbsp;Read More: <a href="https://stocktwits.com/news-articles/markets/equity/tesla-too-good-a-company-to-be-shorted-says-gary-black/cmxyKEtR4cP">Tesla Is ‘Too Good A Company’ To Be Shorted, Says Gary Black: Eyes Multiple ‘Easy’ Fixes At EV Giant</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, the logo of Joby Aviation, Inc. is displayed on a smartphone screen with a stock market chart in the background, on May 04, 2025, in Chongqing, China. (Photo illustration by Cheng Xin/Getty Images)

Joby Inks $61.5 Million Deal To Acquire Another Ready-To-Use Facility In Ohio As It Eyes Doubling eVTOL Production

The new facility spans more than 700,000 feet and is ready for immediate use, the California-based company said.

iShares Trust - iShares ESG Aware 60/40 Balanced Allocation ETF

Short-Term Volatility, Then Markets Move On

Sustained Risk-Off Until Fed Path Is Clear

Little Impact — Fundamentals Still Rule

Other – Comment Below

Markets pulled back after reports that the DOJ opened a criminal investigation into Federal Reserve Chair Jerome Powell, raising concerns about central bank independence. With rate cuts, inflation, and political pressure all in focus, how do you think this standoff will impact markets in 2026?

How Will the Powell Investigation Impact Markets in 2026?

Current Price	$35.89
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